DE69232161D1 - Bestimmungsmethoden unter Verwendung von induzierter Lumineszenz - Google Patents

Bestimmungsmethoden unter Verwendung von induzierter Lumineszenz

Info

Publication number
DE69232161D1
DE69232161D1 DE69232161T DE69232161T DE69232161D1 DE 69232161 D1 DE69232161 D1 DE 69232161D1 DE 69232161 T DE69232161 T DE 69232161T DE 69232161 T DE69232161 T DE 69232161T DE 69232161 D1 DE69232161 D1 DE 69232161D1
Authority
DE
Germany
Prior art keywords
analyte
pacc
medium
sbp
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232161T
Other languages
English (en)
Other versions
DE69232161T2 (de
Inventor
Edwin F Ullman
Hrair Kirakossian
John S Pease
Daniel B Wagner
Yuri Daniloff
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Siemens Healthcare Diagnostics Products GmbH
Original Assignee
Dade Behring Marburg GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/704,569 external-priority patent/US6251581B1/en
Priority claimed from US07/718,490 external-priority patent/US5340716A/en
Application filed by Dade Behring Marburg GmbH filed Critical Dade Behring Marburg GmbH
Application granted granted Critical
Publication of DE69232161D1 publication Critical patent/DE69232161D1/de
Publication of DE69232161T2 publication Critical patent/DE69232161T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346—Nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/28—1,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/30—1,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/10—1,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/12—1,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • G01N33/56977—HLA or MHC typing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587—Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Nanotechnology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Luminescent Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
DE69232161T 1991-05-22 1992-05-21 Bestimmungsmethoden unter Verwendung von induzierter Lumineszenz Expired - Lifetime DE69232161T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/704,569 US6251581B1 (en) 1991-05-22 1991-05-22 Assay method utilizing induced luminescence
US07/718,490 US5340716A (en) 1991-06-20 1991-06-20 Assay method utilizing photoactivated chemiluminescent label

Publications (2)

Publication Number Publication Date
DE69232161D1 true DE69232161D1 (de) 2001-12-06
DE69232161T2 DE69232161T2 (de) 2002-05-16

Family

ID=27107346

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69233146T Expired - Lifetime DE69233146T2 (de) 1991-05-22 1992-05-21 Partikel, die eine Zusammensetzung beinhalten, die eine chemilumineszierende Verbindung umfassen
DE69233674T Expired - Lifetime DE69233674T2 (de) 1991-05-22 1992-05-21 Homogenes Testsystem zur Bestimmung eines Analytes
DE69232161T Expired - Lifetime DE69232161T2 (de) 1991-05-22 1992-05-21 Bestimmungsmethoden unter Verwendung von induzierter Lumineszenz

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69233146T Expired - Lifetime DE69233146T2 (de) 1991-05-22 1992-05-21 Partikel, die eine Zusammensetzung beinhalten, die eine chemilumineszierende Verbindung umfassen
DE69233674T Expired - Lifetime DE69233674T2 (de) 1991-05-22 1992-05-21 Homogenes Testsystem zur Bestimmung eines Analytes

Country Status (10)

Country Link
EP (4) EP0984282B1 (de)
JP (1) JP3892912B2 (de)
AT (3) ATE208039T1 (de)
AU (1) AU657134B2 (de)
CA (1) CA2069145C (de)
DE (3) DE69233146T2 (de)
DK (1) DK0984282T3 (de)
ES (3) ES2280110T3 (de)
IL (1) IL101945A (de)
PT (1) PT984282E (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
US5578498A (en) * 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
ATE162892T1 (de) * 1992-07-31 1998-02-15 Behringwerke Ag Photoaktivierbare chemiluminizierende matrices
CA2170873A1 (en) * 1993-09-03 1995-03-09 Dariush Davalian Fluorescent oxygen channeling immunoassays
US5783453A (en) * 1995-06-29 1998-07-21 Chiron Diagnostics Corporation Non-separation specific binding chemiluminescent assay
EP0793970A1 (de) * 1996-03-08 1997-09-10 Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk Photodynamische Inaktivierung von Viren
ES2270459T3 (es) * 1996-05-01 2007-04-01 Dade Behring Marburg Gmbh Composiciones quimioluminiscentes y su uso en la deteccion de peroxido de hidrogeno.
DE19756773A1 (de) 1997-12-19 1999-06-24 Dade Behring Marburg Gmbh Neues Verfahren und Diagnosemittel zur Hämostase-Diagnostik
DE19756782A1 (de) 1997-12-19 1999-06-24 Dade Behring Marburg Gmbh Nachweis und Bestimmung festphasenassoziierter Faktoren
WO1999042838A1 (en) 1998-02-18 1999-08-26 Dade Behring Inc. Chemiluminescent compositions for use in detection of multiple analytes
US6365346B1 (en) 1998-02-18 2002-04-02 Dade Behring Inc. Quantitative determination of nucleic acid amplification products
DE19811017A1 (de) 1998-03-13 1999-09-16 Dade Behring Marburg Gmbh Neues Verfahren zur Bestimmung von Plasmaproteinen und Faktoren der Hämostase sowie ein neues, implantierbares Meßgerät
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
AUPP405098A0 (en) * 1998-06-12 1998-07-02 Access Pharmaceuticals Australia Pty Limited Novel methods of preparation of vitamin b12 derivatives suitable for conjugation to pharmaceuticals
US6703248B1 (en) * 1999-12-15 2004-03-09 Dade Behring Marburg Gmbh Particles for diagnostic and therapeutic use
DE50015156D1 (de) 1999-12-22 2008-06-26 Dade Behring Marburg Gmbh Gegen Procalcitonin gerichtete Antikörper, ihre Herstellung und Verwendung
ES2280170T3 (es) 1999-12-22 2007-09-16 Dade Behring Marburg Gmbh Soluciones de procalcitonina humana.
AU2001235996B2 (en) * 2000-02-28 2004-12-02 Daiichi Pure Chemicals Co., Ltd Measuring method using long life fluorescence of excitation type
US7179660B1 (en) 2000-03-06 2007-02-20 Dade Behring Marburg Gmbh Carriers coated with polysaccharides, their preparation and use
US6346384B1 (en) * 2000-03-27 2002-02-12 Dade Behring Inc. Real-time monitoring of PCR using LOCI
EP2341349A1 (de) 2000-05-04 2011-07-06 Siemens Healthcare Diagnostics Products GmbH Verfahren zum Nachweis von Mehranalyten
DE10064827A1 (de) 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
AU2002258546B2 (en) * 2001-03-16 2006-09-07 University Of Utah Research Foundation Fluorescent cobalamins and uses thereof
WO2004005917A1 (ja) 2002-07-08 2004-01-15 Daiichi Pure Chemicals Co., Ltd. 蛍光プローブ
US6764819B2 (en) * 2002-07-16 2004-07-20 Emp Biotech Gmbh Method for chemiluminescent detection
US7696245B2 (en) 2003-03-28 2010-04-13 Sekisui Medical Co., Ltd. Fluorescent probe for zinc
EP1695083A1 (de) 2003-12-01 2006-08-30 Dade Behring Marburg GmbH Homogenes nachweisverfahren
JP2005194244A (ja) 2004-01-09 2005-07-21 Shigenobu Yano 亜鉛イオン蛍光センサー
DE102005026163A1 (de) 2004-08-24 2006-03-02 Dade Behring Marburg Gmbh Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung
DE102004042124B4 (de) * 2004-08-30 2006-07-06 Dade Behring Marburg Gmbh Homogenes Verfahren zur Bestimmung eines Analyten in Gegenwart eines Überschusses von kreuzreagierenden Substanzen
EP1807530A2 (de) * 2004-09-17 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Dreiwertiger metallvermittelter homogener lumineszenz-proximity-assay
US20060166376A1 (en) * 2005-01-21 2006-07-27 Craig Alan R Compositions for use as a signal generation component and methods of using same
US7682839B2 (en) * 2005-03-14 2010-03-23 Lumigen, Inc. Methods using novel chemiluminescent labels
IL168184A (en) * 2005-04-21 2011-11-30 Univ Ariel Res & Dev Co Ltd Use of a ligand-photosensitizer conjugate in combination with a chemiluminescent agent in the manufacture of a medicament for photodynamic therapy
DE102005022047A1 (de) 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
GB0520436D0 (en) * 2005-10-07 2005-11-16 Photobiotics Ltd Biological materials and uses thereof
US7732153B2 (en) * 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
JP5553615B2 (ja) * 2007-03-01 2014-07-16 アボット・ラボラトリーズ プロゾーン現象の低減を示すイムノアッセイ
DE102007017906A1 (de) 2007-04-17 2008-10-23 Dade Behring Marburg Gmbh Verfahren zur Bestimmung der Reaktions-Lag-Phase in einer analytabhängigen Reaktion
US7790401B2 (en) * 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
DE102008049601A1 (de) 2008-09-30 2010-04-01 Siemens Healthcare Diagnostics Products Gmbh Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay
EP2177624A1 (de) * 2008-10-02 2010-04-21 Siemens Healthcare Diagnostics Products GmbH Blutgerinnungs-Assays
JP5419775B2 (ja) * 2010-03-30 2014-02-19 日本電信電話株式会社 測定用基板、並びに、これを用いた生化学的結合形成および生化学的結合量の測定方法
EP2395354A1 (de) 2010-06-10 2011-12-14 Siemens Healthcare Diagnostics Products GmbH Homogener Aktivitätstest zur Bestimmung von enzymatischen Reaktionen
EP2471945A1 (de) 2010-12-30 2012-07-04 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Bestimmung von Inhibitoren der Gerinnung
RU2473885C2 (ru) * 2011-02-02 2013-01-27 Государственное образовательное учреждение высшего профессионального образования "Самарский государственный университет" Количественный анализ тиомочевины и флуоресцеина натрия при их совместном присутствии в пластовых водах
DE102011007546A1 (de) 2011-04-15 2012-10-18 Humboldt-Universität Zu Berlin Messvorrichtung für eine Messung einer Singulettsauerstoff-Lumineszenz
US20140235495A1 (en) 2011-09-23 2014-08-21 Siemens Healthcare Diagnostics Inc. Cell response assay for cancer and methods of producing and using same
EP2708892B1 (de) 2012-09-18 2015-04-15 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Bestimmung Plättchen-assoziierter Analyten
DE102012220083B3 (de) * 2012-11-05 2014-03-06 Technische Universität Dresden Verfahren und System zum direkten, strahlungslosen Energietransfer über flüssige Phasengrenzen
WO2014152322A1 (en) 2013-03-15 2014-09-25 Siemens Healthcare Diagnostics Inc. Heterogeneous luminescent oxygen channeling immunoassays
EP2790019A1 (de) 2013-04-10 2014-10-15 Siemens Healthcare Diagnostics Products GmbH High Dose Hook Erkennung
US10124072B2 (en) * 2013-09-18 2018-11-13 Caliper Life Sciences, Inc. In-vivo reactive species imaging
GB201319180D0 (en) * 2013-10-30 2013-12-11 Mast Group Ltd Nucleic acid probe
ES2614352T3 (es) 2014-03-11 2017-05-30 Siemens Healthcare Diagnostics Products Gmbh Método para la detección de moduladores de la interacción de GPIb-trombina
EP3123151B1 (de) * 2014-03-26 2018-11-28 Siemens Healthcare Diagnostics Inc. Lumineszentes sauerstoffkanalisierungs-immunassay mit drei antikörpern und verfahren zur herstellung und verwendung davon
EP2955517A1 (de) 2014-06-10 2015-12-16 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Stabilisierung von Körperflüssigkeitsproben durch die Zugabe von Detergenz
AU2017370942A1 (en) * 2016-12-07 2019-06-13 Progenity Inc. Gastrointestinal tract detection methods, devices and systems
EP3413051B1 (de) 2017-06-09 2020-07-29 Siemens Healthcare Diagnostics Products GmbH Aktivierungstest zur diagnose einer heparin-induzierten thrombozytopenie
ES2862434T3 (es) 2017-08-02 2021-10-07 Siemens Healthcare Diagnostics Products Gmbh Prueba de unión para el diagnóstico de trombocitopenia inducida por heparina
WO2019043553A1 (en) * 2017-08-31 2019-03-07 3M Innovative Properties Company IDENTIFICATION OF MACHINE READABLE PERIODIC PATTERNS
EP3514541A1 (de) * 2018-01-17 2019-07-24 Siemens Healthcare Diagnostics Products GmbH Verfahren zur quantitativen bestimmung eines therapeutischen tnf-alpha inhibitors
CN108676555B (zh) * 2018-05-28 2020-11-20 青岛农业大学 一种含铕离子液体红光材料及制备方法和应用
CN110736737A (zh) * 2018-07-18 2020-01-31 博阳生物科技（上海）有限公司 一种用于化学发光检测的微球组合物及其应用
CN116577512A (zh) * 2019-07-19 2023-08-11 科美博阳诊断技术(上海)有限公司 一种供体试剂在诊断主体心肌损伤中的用途
CN113125705B (zh) * 2019-12-31 2023-08-04 科美诊断技术(苏州)有限公司 一种肌红蛋白的均相检测试剂盒及其应用
KR102526333B1 (ko) * 2020-03-19 2023-04-26 인더스트리얼 테크놀로지 리서치 인스티튜트 검출 시약, 검출 장치 및 1차 아미드 화합물의 검출 방법
CN111795960B (zh) * 2020-08-10 2022-08-09 齐齐哈尔大学 一种光谱法和比色法检测不同形式碘的分子平台及其制备方法和应用
EP4334700A1 (de) * 2021-05-07 2024-03-13 Seegene, Inc. Verfahren und system zur bestimmung der konzentration magnetischer kügelchen in einer suspension
EP4239338A1 (de) 2022-03-03 2023-09-06 Siemens Healthcare Diagnostics Products GmbH Globaltest zur feststellung des status des blutgerinnungssystems
EP4325224A1 (de) 2022-08-18 2024-02-21 Siemens Healthcare Diagnostics Products GmbH Thrombozytenaktivierungstest zur diagnose einer heparin-induzierten thrombozytopenie
CN116429752B (zh) * 2023-02-13 2024-07-19 科美博阳诊断技术(上海)有限公司 Afp检测试剂盒及其使用方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3720622A (en) * 1970-01-02 1973-03-13 American Cyanamid Co Generation of light from the decomposition of dioxetaneones in the presence of a fluorescer
AU517292B2 (en) * 1978-06-20 1981-07-23 Syva Co. Fluorescence quenching system
CA1190838A (en) * 1981-07-17 1985-07-23 Cavit Akin Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer
CA1273552A (en) * 1985-12-23 1990-09-04 Michael J. Heller Fluorescent stokes shift probes for polynucleotide hybridization assays
US4959182A (en) * 1986-07-17 1990-09-25 Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US5004565A (en) * 1986-07-17 1991-04-02 The Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US5616729A (en) * 1986-07-17 1997-04-01 Board Of Governors Of Wayne State University Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers
US4891324A (en) * 1987-01-07 1990-01-02 Syntex (U.S.A.) Inc. Particle with luminescer for assays
US4881191A (en) * 1987-01-13 1989-11-14 Hewlett-Packard Company Multichannel decimation/interpolation filter
AU636110B2 (en) * 1988-06-08 1993-04-22 Nichols Institute Diagnostics Assays utilizing sensitizer-induced production of detectable signal
EP0441948A4 (en) * 1989-09-06 1992-06-03 Tropix, Inc. Synthesis of stable, water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor
WO1991005605A1 (en) 1989-10-10 1991-05-02 Kosak Kenneth M Cyclodextrin labels for immunoassay and biochemical analysis
DE69125992T2 (de) * 1990-09-14 1997-08-21 Tosoh Corp Verfahren und Kit für Immunoassay

Also Published As

Publication number Publication date
EP0984281B1 (de) 2007-01-03
AU657134B2 (en) 1995-03-02
JPH05180773A (ja) 1993-07-23
DK0984282T3 (da) 2003-11-17
PT984282E (pt) 2003-12-31
CA2069145C (en) 2007-07-31
EP0515194A3 (en) 1993-10-20
DE69232161T2 (de) 2002-05-16
EP0515194B1 (de) 2001-10-31
EP1418430A2 (de) 2004-05-12
ES2204050T3 (es) 2004-04-16
EP1418430A3 (de) 2004-09-01
ATE246360T1 (de) 2003-08-15
EP0984281A3 (de) 2000-06-07
DE69233674T2 (de) 2007-10-18
DE69233146D1 (de) 2003-09-04
AU1706892A (en) 1992-11-26
ATE208039T1 (de) 2001-11-15
EP0515194A2 (de) 1992-11-25
ES2168092T3 (es) 2002-06-01
DE69233146T2 (de) 2004-04-29
IL101945A0 (en) 1992-12-30
ES2280110T3 (es) 2007-09-01
EP0984282B1 (de) 2003-07-30
JP3892912B2 (ja) 2007-03-14
ATE350665T1 (de) 2007-01-15
CA2069145A1 (en) 1992-11-23
EP0984282A2 (de) 2000-03-08
EP0984282A3 (de) 2000-06-07
DE69233674D1 (de) 2007-02-15
EP0984281A2 (de) 2000-03-08
IL101945A (en) 1998-02-08

Similar Documents

Publication Publication Date Title
ATE208039T1 (de) Bestimmungsmethoden unter verwendung von induzierter lumineszenz
DE69616243D1 (de) Testvorrichtung mit einem stabilen Kopplungsfarbstoff zur Bestimmung von Analyten
DE69623458D1 (de) Einstufige immunochromatographische vorrichtung und verfahren zu ihrer verwendung
ATE365226T1 (de) Kupplungsfarbstoff zur spektrophotometrischen bestimmung von analyten
DE69521104D1 (de) Spezifische Bindungstests und Reagenzien dafür
ATE86670T1 (de) Verwendung von oxidase-enzymsystemen in chemilumineszierenden tests.
DK0402997T3 (da) Fremgangsmåde til bestemmelse af nukleinsyre
FI875210A (fi) Foerfarande och testanordning foer paovisning av ett aemne i ett prov.
ATE67599T1 (de) Heterogenes immunoassay.
EP0392808A3 (de) Enzymlumineszenztest
AU1718588A (en) Method for the determination of albumin in biological fluids
NO175024C (no) Agglutineringsreagens og dets anvendelse for detektering av et antigen, antistoffer eller andre analytter, samt prövesett omfattende reagensen
EP0368208A3 (de) Immunoassay-Verfahren und Testsatz dafür
DE69514607D1 (de) Verfahren zur Bestimmung von Harnstoff Stickstoff
ATE223049T1 (de) Stabilisierung von standardlösungen durch konjugate
HUT53230A (en) Method for radioimmunological detecting prostaglandin e down 2 content

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH, , DE

R071 Expiry of right

Ref document number: 515194

Country of ref document: EP