ATE86670T1 - Verwendung von oxidase-enzymsystemen in chemilumineszierenden tests. - Google Patents
Verwendung von oxidase-enzymsystemen in chemilumineszierenden tests.Info
- Publication number
- ATE86670T1 ATE86670T1 AT87401818T AT87401818T ATE86670T1 AT E86670 T1 ATE86670 T1 AT E86670T1 AT 87401818 T AT87401818 T AT 87401818T AT 87401818 T AT87401818 T AT 87401818T AT E86670 T1 ATE86670 T1 AT E86670T1
- Authority
- AT
- Austria
- Prior art keywords
- chemiluminescent
- oxidase
- reagent
- analyte
- oxidase enzyme
- Prior art date
Links
- 102000004316 Oxidoreductases Human genes 0.000 title abstract 4
- 108090000854 Oxidoreductases Proteins 0.000 title abstract 4
- 238000003556 assay Methods 0.000 title 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 3
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 abstract 2
- 239000012491 analyte Substances 0.000 abstract 2
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 abstract 1
- 108010093894 Xanthine oxidase Proteins 0.000 abstract 1
- 102100033220 Xanthine oxidase Human genes 0.000 abstract 1
- 238000004458 analytical method Methods 0.000 abstract 1
- 239000003623 enhancer Substances 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 230000000977 initiatory effect Effects 0.000 abstract 1
- 229910052742 iron Inorganic materials 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- HWYHZTIRURJOHG-UHFFFAOYSA-N luminol Chemical compound O=C1NNC(=O)C2=C1C(N)=CC=C2 HWYHZTIRURJOHG-UHFFFAOYSA-N 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 239000000523 sample Substances 0.000 abstract 1
- 230000009870 specific binding Effects 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6816—Hybridisation assays characterised by the detection means
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/531—Production of immunochemical test materials
- G01N33/532—Production of labelled immunochemicals
- G01N33/535—Production of labelled immunochemicals with enzyme label or co-enzymes, co-factors, enzyme inhibitors or enzyme substrates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/968—High energy substrates, e.g. fluorescent, chemiluminescent, radioactive
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Engineering & Computer Science (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8611415A FR2602592B1 (fr) | 1986-08-06 | 1986-08-06 | Utilisation du systeme enzymatique xanthine-oxydase en immuno-analyse, procedes de dosage correspondants et coffrets de reactifs necessaires pour la mise en oeuvre de ces procedes. |
| EP87401818A EP0256932B1 (de) | 1986-08-06 | 1987-08-05 | Verwendung von Oxidase-Enzymsystemen in chemilumineszierenden Tests |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE86670T1 true ATE86670T1 (de) | 1993-03-15 |
Family
ID=9338101
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT87401818T ATE86670T1 (de) | 1986-08-06 | 1987-08-05 | Verwendung von oxidase-enzymsystemen in chemilumineszierenden tests. |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US4933276A (de) |
| EP (1) | EP0256932B1 (de) |
| JP (1) | JPH0716438B2 (de) |
| AT (1) | ATE86670T1 (de) |
| DE (1) | DE3784589T2 (de) |
| FR (1) | FR2602592B1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0533764B1 (de) * | 1990-06-12 | 1997-08-06 | British Technology Group Ltd | Antioxidanttest |
| EP0480361A3 (en) * | 1990-10-11 | 1992-11-25 | Takeda Chemical Industries, Ltd. | Quantitation by chemiluminescence using photosenstive substance |
| GB9026538D0 (en) * | 1990-12-06 | 1991-01-23 | Knight Scient Ltd | Filtration arrangement |
| US5340714A (en) * | 1992-05-08 | 1994-08-23 | Monitor Diagnostics, Inc. | Use of nonmetallic tetrapyrrole molecules and novel signal solutions in chemiluminescent reactions and assays |
| JP3207933B2 (ja) * | 1992-09-09 | 2001-09-10 | 株式会社ヤトロン | アクリジニウム誘導体の発光方法及びそれを用いた検査対象物質の検出方法 |
| GB2289334B (en) * | 1994-05-10 | 1998-08-26 | Molecular Light Technology Lim | Enzyme linked chemiluminescent assay |
| US5565326A (en) | 1994-05-31 | 1996-10-15 | Johnson & Johnson Clinical Diagnostics, Inc. | Separation-free specific binding assays using anti-inhibitor antibodies |
| US5589344A (en) | 1994-06-15 | 1996-12-31 | Johnson & Johnson Clinical Diagnostics, Inc. | Test kit and method for competitive specific binding assay |
| US6319670B1 (en) | 1995-05-09 | 2001-11-20 | Meso Scale Technology Llp | Methods and apparatus for improved luminescence assays using microparticles |
| US5679519A (en) * | 1995-05-09 | 1997-10-21 | Oprandy; John J. | Multi-label complex for enhanced sensitivity in electrochemiluminescence assay |
| US5567302A (en) * | 1995-06-07 | 1996-10-22 | Molecular Devices Corporation | Electrochemical system for rapid detection of biochemical agents that catalyze a redox potential change |
| GB9514594D0 (en) * | 1995-07-17 | 1995-09-13 | Johnson & Johnson Clin Diag | Chemiluminescent analytical method |
| AU1429397A (en) * | 1995-12-29 | 1997-07-28 | A And D Assay, Incorporated | Labeled vitamin d compounds and the use thereof |
| US6001573A (en) * | 1996-06-14 | 1999-12-14 | Packard Bioscience B.V. | Use of porphyrins as a universal label |
| EP0812920A1 (de) * | 1996-06-14 | 1997-12-17 | Packard Instrument B.V. | Verwendung von Porphyrinen bei einem Verfahren zur Instrumental-Erkennung |
| US5856194A (en) | 1996-09-19 | 1999-01-05 | Abbott Laboratories | Method for determination of item of interest in a sample |
| US5795784A (en) | 1996-09-19 | 1998-08-18 | Abbott Laboratories | Method of performing a process for determining an item of interest in a sample |
| EP2060630B1 (de) | 1997-04-10 | 2012-10-24 | Stichting Katholieke Universiteit University Medical Centre Nijmegen | PCA3, PCA3-Gene und Verfahren zu ihrer Verwendung |
| JP4838932B2 (ja) * | 1997-08-21 | 2011-12-14 | メイン メディカル センター | 過酸化物に基づく化学発光の検量方法、並びにそのために用いる化合物 |
| DE19846148C2 (de) * | 1998-10-01 | 2002-10-10 | Igor Popov | Verfahren zur Beurteilung der oxidativen Modifikation proteinhaltiger Stoffe mittels Messung ihrer antiradikalen Aktivität |
| DE60027027T2 (de) | 1999-09-29 | 2006-11-30 | Diagnocure Inc. | Pca3 mrna in gutartigen und bösartigen prostatageweben |
| US6723851B2 (en) * | 2001-10-31 | 2004-04-20 | Quest Diagnostics Investment Incorporated | Chemiluminescent compounds and use thereof |
| CA2513780C (en) | 2003-02-07 | 2014-12-30 | Diagnocure Inc. | Method to detect prostate cancer from a urine sample |
| CA2491067A1 (en) | 2004-12-24 | 2006-06-24 | Stichting Katholieke Universiteit | Mrna rations in urinary sediments and/or urine as a prognostic marker for prostate cancer |
| US20070238140A1 (en) * | 2006-04-07 | 2007-10-11 | Pentoney Stephen L Jr | Method For Multiplex Bead-Based Assays Using Chemiluminescence and Fluorescence |
| JP6588262B2 (ja) | 2015-07-15 | 2019-10-09 | Ntn株式会社 | 等速自在継手の軸部材の鍛造方法 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4604364A (en) * | 1974-01-04 | 1986-08-05 | Kosak Kenneth M | Bioluminescent tracer composition and method of use in immunoassays |
| SE7811630L (sv) * | 1977-11-17 | 1979-05-18 | Welsh Nat School Med | Metod for uppteckt eller mengdbestemning av substanser med anvendning av merkningsteknik |
| US4363759A (en) * | 1978-04-10 | 1982-12-14 | Miles Laboratories, Inc. | Chemiluminescent-labeled haptens and antigens |
| US4235869A (en) * | 1978-05-16 | 1980-11-25 | Syva Company | Assay employing a labeled Fab-fragment ligand complex |
| DE2965849D1 (en) * | 1978-08-18 | 1983-08-18 | Kyowa Hakko Kogyo Kk | Method and test composition for the determination of a substrate for xanthine-oxidase, including a novel xanthine-oxidase and method for the preparation thereof |
| US4376825A (en) * | 1979-05-07 | 1983-03-15 | Syva Company | Enzyme amplification compounds for assays for androgens |
| US4375972A (en) * | 1979-10-17 | 1983-03-08 | Allied Corporation | Heterogeneous chemiluminescent immunoassays utilizing metallo porphyrin tag |
| JPS56109597A (en) * | 1980-02-01 | 1981-08-31 | Shoichi Shimizu | Detection with luciferin analog |
| US4486530A (en) | 1980-08-04 | 1984-12-04 | Hybritech Incorporated | Immunometric assays using monoclonal antibodies |
| US4358535A (en) * | 1980-12-08 | 1982-11-09 | Board Of Regents Of The University Of Washington | Specific DNA probes in diagnostic microbiology |
| US4629690A (en) * | 1981-09-18 | 1986-12-16 | Syntex (U.S.A.) Inc. | Homogeneous enzyme specific binding assay on non-porous surface |
| EP0116454B1 (de) * | 1983-02-11 | 1987-04-29 | National Research Development Corporation | Erhöhte lumineszierende oder luminometrische Prüfung |
| EP0170652A4 (de) * | 1984-01-27 | 1988-08-23 | Molecular Biosystems Inc | Test für immobilisierte reportergruppen. |
| US4617261A (en) * | 1984-03-21 | 1986-10-14 | Cetus Corporation | Process for labeling nucleic acids and hybridization probes |
| US4563417A (en) * | 1984-08-31 | 1986-01-07 | Miles Laboratories, Inc. | Nucleic acid hybridization assay employing antibodies to intercalation complexes |
| US4657853A (en) * | 1984-09-14 | 1987-04-14 | E. I. Du Pont De Nemours And Company | Immunoassays utilizing covalent conjugates of polymerized enzyme and antibody |
| US4794073A (en) * | 1985-07-10 | 1988-12-27 | Molecular Diagnostics, Inc. | Detection of nucleic acid hybrids by prolonged chemiluminescence |
| US4835101A (en) * | 1986-02-10 | 1989-05-30 | Kallestad Diagnostics, Inc. | Luminescent analyses with enhanced storage stability |
-
1986
- 1986-08-06 FR FR8611415A patent/FR2602592B1/fr not_active Expired
-
1987
- 1987-08-04 US US07/081,159 patent/US4933276A/en not_active Expired - Fee Related
- 1987-08-05 DE DE8787401818T patent/DE3784589T2/de not_active Expired - Fee Related
- 1987-08-05 EP EP87401818A patent/EP0256932B1/de not_active Expired - Lifetime
- 1987-08-05 AT AT87401818T patent/ATE86670T1/de not_active IP Right Cessation
- 1987-08-06 JP JP62197256A patent/JPH0716438B2/ja not_active Expired - Lifetime
-
1990
- 1990-06-11 US US07/536,181 patent/US5108893A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63106543A (ja) | 1988-05-11 |
| US4933276A (en) | 1990-06-12 |
| JPH0716438B2 (ja) | 1995-03-01 |
| FR2602592B1 (fr) | 1989-06-30 |
| EP0256932A3 (en) | 1988-08-03 |
| DE3784589T2 (de) | 1993-07-29 |
| FR2602592A1 (fr) | 1988-02-12 |
| EP0256932A2 (de) | 1988-02-24 |
| US5108893A (en) | 1992-04-28 |
| DE3784589D1 (de) | 1993-04-15 |
| EP0256932B1 (de) | 1993-03-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE86670T1 (de) | Verwendung von oxidase-enzymsystemen in chemilumineszierenden tests. | |
| ATE63167T1 (de) | Heterogener spezifischer bindungstest unter verwendung eines anhaeufbaren bindungsreagens. | |
| DE69232161T2 (de) | Bestimmungsmethoden unter Verwendung von induzierter Lumineszenz | |
| DK0649535T3 (da) | Fremgangsmåde til at forbedre målepræcisionen i optisk biosensor assays med detektering af rumligt dæmpede bølger | |
| NO164866C (no) | Reagens og forsoeksinnretning til bestemmelse av tilstedevaerelsen av leukocytter, esterase og protease i en proeve. | |
| DE69214906D1 (de) | Homogene Immunotests unter Verwendung von Enzym-Inhibitoren | |
| YU46053B (sh) | Postopek za specifično določanje vsebnosti serumskega fruktozamina | |
| FI950507A (fi) | Määritysmenetelmä proteiinin määrittämiseksi biologisesta näytteestä | |
| DK0533719T3 (da) | Fremgangsmåde til påvisning og/eller bestemmelse af hormoner | |
| ATE193600T1 (de) | Verfahren zur stabilisierung von enzym-konjugaten | |
| FI875210A (fi) | Foerfarande och testanordning foer paovisning av ett aemne i ett prov. | |
| DE3850346D1 (de) | Verfahren zur Selbstdurchführung von Enzymkinetik. | |
| ES8606947A1 (es) | Un inmunoensayo marcado con un inhibidor de enzima | |
| ATE127588T1 (de) | Geminale diphenyl-derivate und ihre verwendung in immunotests. | |
| ES2070129T3 (es) | Ensayo de aglutinacion. | |
| ES2169211T3 (es) | Ensayos de proteccion de micelas. | |
| NO179468C (no) | Fremgangsmåte for å bestemme antistoff og assayreagenssett for dette | |
| ATE214428T1 (de) | Von enzymen katalysierte chemilumineszente detektion von proteinen und nukleinsäuren durch verwendung von hydroxyaryl-cyclischen diacylhydrazid-zusammensetzungen | |
| EP0379347A3 (de) | Enzym- markierter Rezeptor-Zusammensetzung,Diagnosesatz und Verwendung in einem Verfahren zum Nachweis |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |