ATE246360T1 - Partikel, die eine zusammensetzung beinhalten, die eine chemilumineszierende verbindung umfassen - Google Patents

Partikel, die eine zusammensetzung beinhalten, die eine chemilumineszierende verbindung umfassen

Info

Publication number
ATE246360T1
ATE246360T1 AT99121551T AT99121551T ATE246360T1 AT E246360 T1 ATE246360 T1 AT E246360T1 AT 99121551 T AT99121551 T AT 99121551T AT 99121551 T AT99121551 T AT 99121551T AT E246360 T1 ATE246360 T1 AT E246360T1
Authority
AT
Austria
Prior art keywords
analyte
pacc
medium
chemiluminescent compound
sbp
Prior art date
Application number
AT99121551T
Other languages
English (en)
Inventor
Edwin F Ullman
Hrair Kirakossian
John S Pease
Daniel B Wagner
Yuri Daniloff
Original Assignee
Dade Behring Marburg Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/704,569 external-priority patent/US6251581B1/en
Priority claimed from US07/718,490 external-priority patent/US5340716A/en
Application filed by Dade Behring Marburg Gmbh filed Critical Dade Behring Marburg Gmbh
Application granted granted Critical
Publication of ATE246360T1 publication Critical patent/ATE246360T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54346Nanoparticles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D265/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/281,4-Oxazines; Hydrogenated 1,4-oxazines
    • C07D265/301,4-Oxazines; Hydrogenated 1,4-oxazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/121,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D327/00Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06Six-membered rings
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/5436Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand physically entrapped within the solid phase
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • G01N33/56977HLA or MHC typing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G01N33/587Nanoparticles

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Nanotechnology (AREA)
  • Zoology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Luminescent Compositions (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
AT99121551T 1991-05-22 1992-05-21 Partikel, die eine zusammensetzung beinhalten, die eine chemilumineszierende verbindung umfassen ATE246360T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/704,569 US6251581B1 (en) 1991-05-22 1991-05-22 Assay method utilizing induced luminescence
US07/718,490 US5340716A (en) 1991-06-20 1991-06-20 Assay method utilizing photoactivated chemiluminescent label

Publications (1)

Publication Number Publication Date
ATE246360T1 true ATE246360T1 (de) 2003-08-15

Family

ID=27107346

Family Applications (3)

Application Number Title Priority Date Filing Date
AT92304630T ATE208039T1 (de) 1991-05-22 1992-05-21 Bestimmungsmethoden unter verwendung von induzierter lumineszenz
AT99121547T ATE350665T1 (de) 1991-05-22 1992-05-21 Homogenes testsystem zur bestimmung eines analytes
AT99121551T ATE246360T1 (de) 1991-05-22 1992-05-21 Partikel, die eine zusammensetzung beinhalten, die eine chemilumineszierende verbindung umfassen

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT92304630T ATE208039T1 (de) 1991-05-22 1992-05-21 Bestimmungsmethoden unter verwendung von induzierter lumineszenz
AT99121547T ATE350665T1 (de) 1991-05-22 1992-05-21 Homogenes testsystem zur bestimmung eines analytes

Country Status (10)

Country Link
EP (4) EP0984281B1 (de)
JP (1) JP3892912B2 (de)
AT (3) ATE208039T1 (de)
AU (1) AU657134B2 (de)
CA (1) CA2069145C (de)
DE (3) DE69233146T2 (de)
DK (1) DK0984282T3 (de)
ES (3) ES2280110T3 (de)
IL (1) IL101945A (de)
PT (1) PT984282E (de)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5578498A (en) 1991-05-22 1996-11-26 Behringwerke Ag Metal chelate containing compositions for use in chemiluminescent assays
US6251581B1 (en) 1991-05-22 2001-06-26 Dade Behring Marburg Gmbh Assay method utilizing induced luminescence
JP3464798B2 (ja) * 1992-07-31 2003-11-10 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング 光活性化化学発光基質
DE69417242T2 (de) * 1993-09-03 1999-07-08 Behringwerke AG, 35041 Marburg Fluoreszenz-sauerstoffkanalisation-immunteste
US5783453A (en) * 1995-06-29 1998-07-21 Chiron Diagnostics Corporation Non-separation specific binding chemiluminescent assay
EP0793970A1 (de) * 1996-03-08 1997-09-10 Rotkreuzstiftung Zentrallaboratorium Blutspendedienst Srk Photodynamische Inaktivierung von Viren
EP0852012B1 (de) * 1996-05-01 2006-07-26 Dade Behring Marburg GmbH Chemilumineszente zusammensetungen und ihre verwendung zum nachweis von wasserstoffperoxid
DE19756773A1 (de) 1997-12-19 1999-06-24 Dade Behring Marburg Gmbh Neues Verfahren und Diagnosemittel zur Hämostase-Diagnostik
DE19756782A1 (de) * 1997-12-19 1999-06-24 Dade Behring Marburg Gmbh Nachweis und Bestimmung festphasenassoziierter Faktoren
WO1999042838A1 (en) 1998-02-18 1999-08-26 Dade Behring Inc. Chemiluminescent compositions for use in detection of multiple analytes
US6365346B1 (en) * 1998-02-18 2002-04-02 Dade Behring Inc. Quantitative determination of nucleic acid amplification products
DE19811017A1 (de) 1998-03-13 1999-09-16 Dade Behring Marburg Gmbh Neues Verfahren zur Bestimmung von Plasmaproteinen und Faktoren der Hämostase sowie ein neues, implantierbares Meßgerät
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes
AUPP405098A0 (en) * 1998-06-12 1998-07-02 Access Pharmaceuticals Australia Pty Limited Novel methods of preparation of vitamin b12 derivatives suitable for conjugation to pharmaceuticals
US6703248B1 (en) * 1999-12-15 2004-03-09 Dade Behring Marburg Gmbh Particles for diagnostic and therapeutic use
DE50015156D1 (de) 1999-12-22 2008-06-26 Dade Behring Marburg Gmbh Gegen Procalcitonin gerichtete Antikörper, ihre Herstellung und Verwendung
DE50014159D1 (de) 1999-12-22 2007-04-26 Dade Behring Marburg Gmbh Lösungen von humanem Procalcitonin
ATE397208T1 (de) * 2000-02-28 2008-06-15 Daiichi Pure Chemicals Co Ltd Messverfahren basierend auf fluoreszenz- energie- transfer mit einem donor langer fluoreszenzlebenszeit
WO2001067105A1 (en) 2000-03-06 2001-09-13 Dade Behring Marburg Gmbh Carriers coated with polysaccharides, their preparation and use
US6346384B1 (en) * 2000-03-27 2002-02-12 Dade Behring Inc. Real-time monitoring of PCR using LOCI
WO2001084157A2 (en) * 2000-05-04 2001-11-08 Dade Behring Marburg Gmbh Compositions for detection of multiple analytes
DE10064827A1 (de) 2000-12-22 2002-06-27 Dade Behring Marburg Gmbh Nachweisverfahren
JP2004535371A (ja) * 2001-03-16 2004-11-25 ユニバーシティ・オブ・ユタ・リサーチ・ファウンデーション 蛍光コバラミンおよびその使用
JP4206378B2 (ja) 2002-07-08 2009-01-07 哲雄 長野 蛍光プローブ
US6764819B2 (en) * 2002-07-16 2004-07-20 Emp Biotech Gmbh Method for chemiluminescent detection
US7696245B2 (en) 2003-03-28 2010-04-13 Sekisui Medical Co., Ltd. Fluorescent probe for zinc
JP2007512543A (ja) 2003-12-01 2007-05-17 デイド・ベーリング・マルブルク・ゲゼルシヤフト・ミツト・ベシユレンクテル・ハフツング ホモジニアスな検出方法
JP2005194244A (ja) 2004-01-09 2005-07-21 Shigenobu Yano 亜鉛イオン蛍光センサー
DE102005026163A1 (de) 2004-08-24 2006-03-02 Dade Behring Marburg Gmbh Gegen den Marburg I Polymorphismus der Faktor VII aktivierenden Protease (FSAP) gerichtete Antikörper, ihre Herstellung und Verwendung
DE102004042124B4 (de) * 2004-08-30 2006-07-06 Dade Behring Marburg Gmbh Homogenes Verfahren zur Bestimmung eines Analyten in Gegenwart eines Überschusses von kreuzreagierenden Substanzen
EP1807530A2 (de) * 2004-09-17 2007-07-18 Novartis Vaccines and Diagnostics, Inc. Dreiwertiger metallvermittelter homogener lumineszenz-proximity-assay
US20060166376A1 (en) * 2005-01-21 2006-07-27 Craig Alan R Compositions for use as a signal generation component and methods of using same
US7682839B2 (en) * 2005-03-14 2010-03-23 Lumigen, Inc. Methods using novel chemiluminescent labels
IL168184A (en) * 2005-04-21 2011-11-30 Univ Ariel Res & Dev Co Ltd Use of a ligand-photosensitizer conjugate in combination with a chemiluminescent agent in the manufacture of a medicament for photodynamic therapy
DE102005022047A1 (de) 2005-05-09 2006-11-30 Dade Behring Marburg Gmbh Bindungspartner des Plazentalen Wachstumsfaktors insbesondere gegen den Plazentalen Wachstumsfaktor gerichtete Antikörper, ihre Herstellung und Verwendung
GB0520436D0 (en) * 2005-10-07 2005-11-16 Photobiotics Ltd Biological materials and uses thereof
US7732153B2 (en) * 2006-05-09 2010-06-08 Beckman Coulter, Inc. Nonseparation assay methods
JP5553615B2 (ja) * 2007-03-01 2014-07-16 アボット・ラボラトリーズ プロゾーン現象の低減を示すイムノアッセイ
DE102007017906A1 (de) 2007-04-17 2008-10-23 Dade Behring Marburg Gmbh Verfahren zur Bestimmung der Reaktions-Lag-Phase in einer analytabhängigen Reaktion
US7790401B2 (en) * 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
US8682408B2 (en) 2008-03-28 2014-03-25 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US11730407B2 (en) 2008-03-28 2023-08-22 Dexcom, Inc. Polymer membranes for continuous analyte sensors
US8583204B2 (en) 2008-03-28 2013-11-12 Dexcom, Inc. Polymer membranes for continuous analyte sensors
DE102008049601A1 (de) 2008-09-30 2010-04-01 Siemens Healthcare Diagnostics Products Gmbh Antikörper zur Bestimmung des Prothrombin-Fragments F2/F1+2 in einem homogenen Immunoassay
EP2177624A1 (de) * 2008-10-02 2010-04-21 Siemens Healthcare Diagnostics Products GmbH Blutgerinnungs-Assays
JP5419775B2 (ja) * 2010-03-30 2014-02-19 日本電信電話株式会社 測定用基板、並びに、これを用いた生化学的結合形成および生化学的結合量の測定方法
EP2395354A1 (de) * 2010-06-10 2011-12-14 Siemens Healthcare Diagnostics Products GmbH Homogener Aktivitätstest zur Bestimmung von enzymatischen Reaktionen
EP2471945A1 (de) 2010-12-30 2012-07-04 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Bestimmung von Inhibitoren der Gerinnung
RU2473885C2 (ru) * 2011-02-02 2013-01-27 Государственное образовательное учреждение высшего профессионального образования "Самарский государственный университет" Количественный анализ тиомочевины и флуоресцеина натрия при их совместном присутствии в пластовых водах
DE102011007546A1 (de) 2011-04-15 2012-10-18 Humboldt-Universität Zu Berlin Messvorrichtung für eine Messung einer Singulettsauerstoff-Lumineszenz
EP2748337B1 (de) 2011-09-23 2019-08-07 Siemens Healthcare Diagnostics Inc. Zellreaktionstest für krebs sowie verfahren zu seiner herstellung und anwendung
EP2708892B1 (de) 2012-09-18 2015-04-15 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Bestimmung Plättchen-assoziierter Analyten
DE102012220083B3 (de) * 2012-11-05 2014-03-06 Technische Universität Dresden Verfahren und System zum direkten, strahlungslosen Energietransfer über flüssige Phasengrenzen
US10371643B2 (en) 2013-03-15 2019-08-06 Siemens Healthcare Diagnostics Inc. Luminescent oxygen channeling immunoassays
EP2790019A1 (de) 2013-04-10 2014-10-15 Siemens Healthcare Diagnostics Products GmbH High Dose Hook Erkennung
US10124072B2 (en) * 2013-09-18 2018-11-13 Caliper Life Sciences, Inc. In-vivo reactive species imaging
GB201319180D0 (en) * 2013-10-30 2013-12-11 Mast Group Ltd Nucleic acid probe
EP2919013B1 (de) 2014-03-11 2016-11-02 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Detektion von Modulatoren der GPIb-Thrombin-Interaktion
ES2713428T3 (es) * 2014-03-26 2019-05-21 Siemens Healthcare Diagnostics Inc Inmunoensayo de canalización de oxígeno luminiscente utilizando tres anticuerpos y métodos de producción y uso de los mismos
EP2955517A1 (de) 2014-06-10 2015-12-16 Siemens Healthcare Diagnostics Products GmbH Verfahren zur Stabilisierung von Körperflüssigkeitsproben durch die Zugabe von Detergenz
EP3551046B1 (de) * 2016-12-07 2023-07-19 Biora Therapeutics, Inc. Verfahren, vorrichtungen und systeme zur detektion des magen-darm-trakts
EP3413051B1 (de) 2017-06-09 2020-07-29 Siemens Healthcare Diagnostics Products GmbH Aktivierungstest zur diagnose einer heparin-induzierten thrombozytopenie
EP3438667B1 (de) 2017-08-02 2020-12-30 Siemens Healthcare Diagnostics Products GmbH Bindungstest zur diagnose einer heparin-induzierten thrombozytopenie
WO2019043553A1 (en) * 2017-08-31 2019-03-07 3M Innovative Properties Company IDENTIFICATION OF MACHINE READABLE PERIODIC PATTERNS
EP3514541A1 (de) 2018-01-17 2019-07-24 Siemens Healthcare Diagnostics Products GmbH Verfahren zur quantitativen bestimmung eines therapeutischen tnf-alpha inhibitors
CN108676555B (zh) * 2018-05-28 2020-11-20 青岛农业大学 一种含铕离子液体红光材料及制备方法和应用
CN116577319A (zh) * 2018-07-18 2023-08-11 上海索昕生物科技有限公司 一种用于化学发光检测的微球组合物及其应用
CN116593712A (zh) * 2019-07-19 2023-08-15 科美博阳诊断技术(上海)有限公司 一种供体试剂在诊断主体心肌损伤中的用途
CN113125705B (zh) * 2019-12-31 2023-08-04 科美诊断技术(苏州)有限公司 一种肌红蛋白的均相检测试剂盒及其应用
KR102526333B1 (ko) * 2020-03-19 2023-04-26 인더스트리얼 테크놀로지 리서치 인스티튜트 검출 시약, 검출 장치 및 1차 아미드 화합물의 검출 방법
CN111795960B (zh) * 2020-08-10 2022-08-09 齐齐哈尔大学 一种光谱法和比色法检测不同形式碘的分子平台及其制备方法和应用
WO2022235065A1 (en) * 2021-05-07 2022-11-10 Seegene, Inc. Method and system for determining magnetic bead concentration in suspension
EP4239338A1 (de) 2022-03-03 2023-09-06 Siemens Healthcare Diagnostics Products GmbH Globaltest zur feststellung des status des blutgerinnungssystems
EP4325224A1 (de) 2022-08-18 2024-02-21 Siemens Healthcare Diagnostics Products GmbH Thrombozytenaktivierungstest zur diagnose einer heparin-induzierten thrombozytopenie
CN116429752B (zh) * 2023-02-13 2024-07-19 科美博阳诊断技术(上海)有限公司 Afp检测试剂盒及其使用方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3720622A (en) * 1970-01-02 1973-03-13 American Cyanamid Co Generation of light from the decomposition of dioxetaneones in the presence of a fluorescer
AU517292B2 (en) * 1978-06-20 1981-07-23 Syva Co. Fluorescence quenching system
CA1190838A (en) * 1981-07-17 1985-07-23 Cavit Akin Homogeneous nucleic acid hybridization diagnostics by non-radiative energy transfer
CA1273552A (en) * 1985-12-23 1990-09-04 Michael J. Heller Fluorescent stokes shift probes for polynucleotide hybridization assays
US4959182A (en) * 1986-07-17 1990-09-25 Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US5616729A (en) * 1986-07-17 1997-04-01 Board Of Governors Of Wayne State University Enhanced chemiluminescence from 1,2-dioxetanes through energy transfer to tethered fluorescers
US5004565A (en) * 1986-07-17 1991-04-02 The Board Of Governors Of Wayne State University Method and compositions providing enhanced chemiluminescence from 1,2-dioxetanes
US4891324A (en) * 1987-01-07 1990-01-02 Syntex (U.S.A.) Inc. Particle with luminescer for assays
US4881191A (en) * 1987-01-13 1989-11-14 Hewlett-Packard Company Multichannel decimation/interpolation filter
JP2681061B2 (ja) * 1988-06-08 1997-11-19 ロンドン・ダイアグノスティック・インコーポレーテッド 検出可能なシグナルのセンシタイザー誘導発生を利用したアッセイ
WO1991003479A1 (en) * 1989-09-06 1991-03-21 Tropix, Inc. Synthesis of stable, water-soluble chemiluminescent 1,2-dioxetanes and intermediates therefor
WO1991005605A1 (en) 1989-10-10 1991-05-02 Kosak Kenneth M Cyclodextrin labels for immunoassay and biochemical analysis
DE69125992T2 (de) * 1990-09-14 1997-08-21 Tosoh Corp Verfahren und Kit für Immunoassay

Also Published As

Publication number Publication date
DE69232161D1 (de) 2001-12-06
EP0984282A3 (de) 2000-06-07
CA2069145A1 (en) 1992-11-23
DE69232161T2 (de) 2002-05-16
EP0984281A3 (de) 2000-06-07
EP1418430A2 (de) 2004-05-12
CA2069145C (en) 2007-07-31
DE69233674T2 (de) 2007-10-18
EP0515194A2 (de) 1992-11-25
ATE208039T1 (de) 2001-11-15
DK0984282T3 (da) 2003-11-17
AU657134B2 (en) 1995-03-02
DE69233674D1 (de) 2007-02-15
JPH05180773A (ja) 1993-07-23
EP0515194B1 (de) 2001-10-31
ATE350665T1 (de) 2007-01-15
IL101945A (en) 1998-02-08
JP3892912B2 (ja) 2007-03-14
ES2280110T3 (es) 2007-09-01
AU1706892A (en) 1992-11-26
EP0515194A3 (en) 1993-10-20
EP0984281A2 (de) 2000-03-08
ES2204050T3 (es) 2004-04-16
EP1418430A3 (de) 2004-09-01
DE69233146T2 (de) 2004-04-29
DE69233146D1 (de) 2003-09-04
EP0984281B1 (de) 2007-01-03
PT984282E (pt) 2003-12-31
EP0984282B1 (de) 2003-07-30
ES2168092T3 (es) 2002-06-01
IL101945A0 (en) 1992-12-30
EP0984282A2 (de) 2000-03-08

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