DE68927948D1 - Trehalosderivate - Google Patents

Trehalosderivate

Info

Publication number
DE68927948D1
DE68927948D1 DE68927948T DE68927948T DE68927948D1 DE 68927948 D1 DE68927948 D1 DE 68927948D1 DE 68927948 T DE68927948 T DE 68927948T DE 68927948 T DE68927948 T DE 68927948T DE 68927948 D1 DE68927948 D1 DE 68927948D1
Authority
DE
Germany
Prior art keywords
trehalos
derivatives
trehalos derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE68927948T
Other languages
English (en)
Other versions
DE68927948T2 (de
Inventor
Junji Yoshinaga
Takeshi Shogaki
Takoa Kakita
Hiromi Ozeki
Yoshiko Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sawai Pharmaceutical Co Ltd
Original Assignee
Sawai Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sawai Pharmaceutical Co Ltd filed Critical Sawai Pharmaceutical Co Ltd
Publication of DE68927948D1 publication Critical patent/DE68927948D1/de
Application granted granted Critical
Publication of DE68927948T2 publication Critical patent/DE68927948T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE68927948T 1988-08-26 1989-08-17 Trehalosderivate Expired - Lifetime DE68927948T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP21330788 1988-08-26
JP9279189 1989-04-11

Publications (2)

Publication Number Publication Date
DE68927948D1 true DE68927948D1 (de) 1997-05-15
DE68927948T2 DE68927948T2 (de) 1997-08-28

Family

ID=26434171

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68927948T Expired - Lifetime DE68927948T2 (de) 1988-08-26 1989-08-17 Trehalosderivate

Country Status (4)

Country Link
US (1) US5049664A (de)
EP (1) EP0356154B1 (de)
JP (1) JP2930983B2 (de)
DE (1) DE68927948T2 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721109A (en) * 1989-01-18 1998-02-24 Sawai Pharmaceutical Co., Ltd. Method for diagnosing infection caused by acid-fast bacterium
GB2282596B (en) * 1993-10-06 1998-04-15 Ciba Geigy Ag Water-soluble retinoids
US6586006B2 (en) 1994-08-04 2003-07-01 Elan Drug Delivery Limited Solid delivery systems for controlled release of molecules incorporated therein and methods of making same
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
WO1996008979A1 (en) 1994-09-22 1996-03-28 Quadrant Holdings Cambridge Limited Compositions for use in rehydration and nutrition during athletic exercise and methods of making same
JPH08157491A (ja) * 1994-11-30 1996-06-18 Hayashibara Biochem Lab Inc トレハロース誘導体の製造方法
US6964771B1 (en) 1995-06-07 2005-11-15 Elan Drug Delivery Limited Method for stably incorporating substances within dry, foamed glass matrices
US20060165606A1 (en) 1997-09-29 2006-07-27 Nektar Therapeutics Pulmonary delivery particles comprising water insoluble or crystalline active agents
US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
US6352722B1 (en) 1997-12-23 2002-03-05 Quadrant Holdings Cambridge Limited Derivatized carbohydrates, compositions comprised thereof and methods of use thereof
US7442388B2 (en) 2000-05-10 2008-10-28 Weers Jeffry G Phospholipid-based powders for drug delivery
US7871598B1 (en) 2000-05-10 2011-01-18 Novartis Ag Stable metal ion-lipid powdered pharmaceutical compositions for drug delivery and methods of use
US8404217B2 (en) 2000-05-10 2013-03-26 Novartis Ag Formulation for pulmonary administration of antifungal agents, and associated methods of manufacture and use
EP1338638A4 (de) * 2000-09-19 2005-03-23 Hayashibara Biochem Lab Aggregatbildner
CA2468958C (en) 2001-12-19 2012-07-03 Nektar Therapeutics Pulmonary delivery of aminoglycosides
CN101316575B (zh) * 2005-11-30 2011-04-20 日清奥利友集团株式会社 海藻糖脂肪酸酯组合物
WO2007111214A1 (ja) * 2006-03-27 2007-10-04 Otsuka Chemical Co., Ltd. トレハロース化合物および該化合物を含有する医薬
CA3116307C (en) 2010-02-23 2023-10-17 University Of Washington Artificial mycolic acid membranes
FR2980794B1 (fr) * 2011-10-03 2014-11-07 Univ Bordeaux 1 Preparation de polyurethanes et polyesters a partir de composes de type glycolipide
US20130331353A1 (en) * 2012-06-07 2013-12-12 Union College Cell-permeable variants of trehalose and methods for the protection of living cells
US10414787B2 (en) 2013-03-14 2019-09-17 Mars, Incorporated Flavor composition containing HMG glucosides
CN105085585B (zh) * 2014-05-11 2019-02-05 扬州蓝色生物医药科技有限公司 一种鼠李糖苷类化合物及其作为抗多药耐药肿瘤药物的应用
CN103985192B (zh) * 2014-05-30 2016-04-20 广州广电运通金融电子股份有限公司 循环一体机及其分钞装置
CA3134882A1 (en) * 2019-03-29 2020-10-08 Nagase & Co., Ltd. Novel compound and use of same

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE549742A (de) *
FR2319373A1 (fr) * 1975-07-29 1977-02-25 Anvar Nouveau procede d'esterification selective des fonctions alcool primaire de diholosides et produits ainsi obtenus
US4243663A (en) * 1976-06-25 1981-01-06 Ichiro Azuma Glycolipid compositions for transplanted tumor immunotherapy
US4307229A (en) * 1979-11-07 1981-12-22 Avraham Liav 6,6'-Diesters of trehalose and process for the synthesis thereof
JPS58185599A (ja) * 1982-04-26 1983-10-29 Ss Pharmaceut Co Ltd α，α―トレハロース―６，６′―脂肪酸ジエステルの製造方法
JPS5946294A (ja) * 1982-09-10 1984-03-15 Ss Pharmaceut Co Ltd α，α−トレハロ−ス脂肪酸テトラエステル誘導体およびその製造法
GB2133399B (en) * 1982-10-08 1985-08-07 Ss Pharmaceutical Co A,a-trehalose-6,6'-middle chained aliphatic acid diester and a pharmaceutical agent containing the same
CA1202622A (en) * 1982-10-14 1986-04-01 Yoshihiro Nishikawa .alpha..alpha.-TREHALOSE-6,6'-MEDIUM CHAINED LENGHT ALIPHATIC ACID DIESTER AND A PHARMACEUTICAL AGENT CONTAINING THE SAME
DE3248167A1 (de) * 1982-12-27 1984-06-28 Wintershall Ag, 3100 Celle Trehaloselipidtetraester
JPS59157097A (ja) * 1983-02-28 1984-09-06 Ss Pharmaceut Co Ltd α．α―トレハロース脂肪酸テトラエステル誘導体
JPS59181297A (ja) * 1984-03-01 1984-10-15 Ss Pharmaceut Co Ltd α，α‐トレハロース‐６，６′‐中鎖脂肪酸ジエステル及びこれを含有する抗腫瘍剤
JPS60258195A (ja) * 1984-06-05 1985-12-20 Ss Pharmaceut Co Ltd α．α―トレハロース脂肪酸ジエステル誘導体
JPS61130298A (ja) * 1984-11-30 1986-06-18 Ss Pharmaceut Co Ltd α，α−トレハロ−ス脂肪酸ジアミド誘導体およびその製造法
JPS6253926A (ja) * 1985-05-30 1987-03-09 Ss Pharmaceut Co Ltd 抗癌剤
US4612304A (en) * 1985-06-11 1986-09-16 Ss Pharmaceutical Co., Ltd. Antitumor formulation containing lipopolysaccharide with trehalose derivatives
JPS61289038A (ja) * 1985-06-14 1986-12-19 Ss Pharmaceut Co Ltd 抗癌剤
JPS6219598A (ja) * 1985-07-18 1987-01-28 Ss Pharmaceut Co Ltd ２，３，２′，３′−テトラ−Ｏ−アルキル−α，α−トレハロ−ス誘導体
JPS6250478A (ja) * 1985-08-28 1987-03-05 Mitsubishi Electric Corp 黒色処理鋼板の製造方法
JPS6256499A (ja) * 1985-09-06 1987-03-12 Ss Pharmaceut Co Ltd α，α−トレハロ−スエ−テル誘導体
JPS6259117A (ja) * 1985-09-09 1987-03-14 Mazda Motor Corp 自動車のドア構造
JPS6272695A (ja) * 1985-09-25 1987-04-03 Ss Pharmaceut Co Ltd ４，４′−ジ−Ｏ−アルキル−α，α−トレハロ−ス誘導体
JPS62174094A (ja) * 1985-12-16 1987-07-30 Ss Pharmaceut Co Ltd α．α―トレハロース誘導体
WO1990008323A1 (en) * 1989-01-18 1990-07-26 Sawai Pharmaceutical Co., Ltd. Reagent for detecting antibody corresponding to acid-fast bacterium antigen and application thereof

Also Published As

Publication number Publication date
EP0356154A2 (de) 1990-02-28
EP0356154A3 (de) 1992-01-22
US5049664A (en) 1991-09-17
EP0356154B1 (de) 1997-04-09
DE68927948T2 (de) 1997-08-28
JP2930983B2 (ja) 1999-08-09
JPH0347193A (ja) 1991-02-28

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