DK19789A - Dehydrocholcalciferolderivater - Google Patents

Dehydrocholcalciferolderivater

Info

Publication number
DK19789A
DK19789A DK019789A DK19789A DK19789A DK 19789 A DK19789 A DK 19789A DK 019789 A DK019789 A DK 019789A DK 19789 A DK19789 A DK 19789A DK 19789 A DK19789 A DK 19789A
Authority
DK
Denmark
Prior art keywords
dehydrocholcalciferol
derivatives
dehydrocholcalciferol derivatives
Prior art date
Application number
DK019789A
Other languages
English (en)
Other versions
DK19789D0 (da
DK169945B1 (da
Inventor
Bernard Michael Hennessy
Shian-Jan Shiuey
Gary Arthur Truitt
Milan Radoje Uskokovic
Enrico Giuseppe Baggiolini
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of DK19789D0 publication Critical patent/DK19789D0/da
Publication of DK19789A publication Critical patent/DK19789A/da
Application granted granted Critical
Publication of DK169945B1 publication Critical patent/DK169945B1/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK019789A 1988-01-20 1989-01-17 25-Hydroxy-vitamin-D3-derivater, fremgangsmåde til fremstilling deraf samt lægemiddel indeholdende disse forbindelser DK169945B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14593288A 1988-01-20 1988-01-20
US14593288 1988-01-20

Publications (3)

Publication Number Publication Date
DK19789D0 DK19789D0 (da) 1989-01-17
DK19789A true DK19789A (da) 1989-07-21
DK169945B1 DK169945B1 (da) 1995-04-10

Family

ID=22515181

Family Applications (1)

Application Number Title Priority Date Filing Date
DK019789A DK169945B1 (da) 1988-01-20 1989-01-17 25-Hydroxy-vitamin-D3-derivater, fremgangsmåde til fremstilling deraf samt lægemiddel indeholdende disse forbindelser

Country Status (23)

Country Link
EP (1) EP0325279B1 (da)
JP (1) JPH0764806B2 (da)
KR (1) KR960009119B1 (da)
AR (1) AR247551A1 (da)
AT (1) ATE74350T1 (da)
AU (1) AU622139B2 (da)
BG (1) BG60530B2 (da)
CA (1) CA1337529C (da)
DE (1) DE58901056D1 (da)
DK (1) DK169945B1 (da)
ES (1) ES2033467T3 (da)
FI (1) FI90764C (da)
GR (1) GR3004786T3 (da)
HU (1) HU201007B (da)
IE (1) IE60921B1 (da)
IL (1) IL88989A (da)
MC (1) MC1998A1 (da)
NO (1) NO175429C (da)
NZ (1) NZ227641A (da)
PH (1) PH25605A (da)
PT (1) PT89486B (da)
YU (1) YU47298B (da)
ZA (1) ZA8923B (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DE69005897D1 (de) * 1989-05-18 1994-02-24 Hoffmann La Roche Dehydrocholecalciferolderivate.
AU650751B2 (en) * 1991-05-28 1994-06-30 Wisconsin Alumni Research Foundation Novel synthesis of 19-nor vitamin D compounds
ES2091515T3 (es) * 1992-05-20 1996-11-01 Hoffmann La Roche Analogos fluorados de la vitamina d3.
CA2096105A1 (en) * 1992-10-07 1994-04-08 Enrico Giuseppe Baggiolini (Deceased) Vitamin d3 fluorinated analogs
US5753638A (en) * 1992-10-07 1998-05-19 Hoffmann-La Roche Inc. Method of treating hyperproliferative skin disease with Vitamin D3 fluorinated analogs
TW267161B (da) * 1992-11-20 1996-01-01 Hoffmann La Roche
US5401733A (en) * 1993-10-01 1995-03-28 Hoffmann-La Roche Inc. Stable and active metabolites of 1,25-dihydroxy-16-ene-cholecalciferol
US5428029A (en) * 1993-11-24 1995-06-27 Hoffmann-La Roche Inc. Vitamin D3 fluorinated analogs
TW403735B (en) * 1995-11-22 2000-09-01 Hoffmann La Roche 25-hydroxy-16-ene-26, 27-bishomo-cholecalciferol
AU708679B2 (en) * 1996-03-21 1999-08-12 F. Hoffmann-La Roche Ag 1,25-dihydroxy-16,22,23-trisdehydro-cholecalciferol derivatives
SG70009A1 (en) * 1996-05-23 2000-01-25 Hoffmann La Roche Vitamin d3 analogs
US5939408A (en) * 1996-05-23 1999-08-17 Hoffman-La Roche Inc. Vitamin D3 analogs
JPH10316652A (ja) * 1997-05-02 1998-12-02 Duphar Internatl Res Bv １６−デヒドロビタミンｄ化合物の製造方法
US6331642B1 (en) * 1999-07-12 2001-12-18 Hoffmann-La Roche Inc. Vitamin D3 analogs
US9221753B2 (en) * 2004-02-03 2015-12-29 Chugai Seiyaku Kabushiki Kaisha Process for the synthesis of vitamin D compounds and intermediates for the synthesis of the compounds
CA2605815A1 (en) * 2005-04-25 2006-11-02 Cytochroma Inc. Low-calcemic 16,23-diene 25-oxime analogs of 1alpha,25-dihydroxy vitamin d3
US20090137828A1 (en) * 2005-08-18 2009-05-28 Bioxell S.P.A. Synthesis of 1A-Fluoro-25-Hydroxy-16-23E-Diene-26,27-Bishomo-20-Epi-Cholecalciferol

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2384755A1 (fr) * 1977-03-24 1978-10-20 Wisconsin Alumni Res Found Derives de la vitamine d3 ayant une activite antivitamine d
DE2920092A1 (de) * 1978-05-19 1979-11-29 Wisconsin Alumni Res Found Antivitamin d-verbindungen und diese enthaltende pharmazeutische zusammensetzungen
US4360471A (en) * 1981-12-11 1982-11-23 Wisconsin Alumni Research Foundation 23-Dehydro-25-hydroxyvitamin D3
US4508651A (en) * 1983-03-21 1985-04-02 Hoffmann-La Roche Inc. Synthesis of 1α,25-dihydroxyergocalciferol
US4505906A (en) * 1984-01-30 1985-03-19 Wisconsin Alumni Research Foundation Hydroxyvitamin D2 isomers
US4612308A (en) * 1984-11-29 1986-09-16 Hoffmann-La Roche Inc. 25,26-Dehydro-1α,23(S,R)-dihydroxycholecalciferol and its epimers
US4898855A (en) * 1987-09-14 1990-02-06 Hoffman-La Roche Inc. Deuterated analogs of 1,25-dihydroxycholecalciferol
US4804502A (en) * 1988-01-20 1989-02-14 Hoffmann-La Roche Inc. Vitamin D compounds
DE69005897D1 (de) * 1989-05-18 1994-02-24 Hoffmann La Roche Dehydrocholecalciferolderivate.

Also Published As

Publication number Publication date
KR960009119B1 (en) 1996-07-13
IL88989A0 (en) 1989-08-15
FI90764B (fi) 1993-12-15
GR3004786T3 (da) 1993-04-28
ES2033467T3 (es) 1993-03-16
HUT49317A (en) 1989-09-28
IL88989A (en) 1993-08-18
FI90764C (fi) 1994-03-25
MC1998A1 (fr) 1990-01-26
CA1337529C (en) 1995-11-07
NO175429C (no) 1994-10-12
NZ227641A (en) 1991-06-25
AR247551A1 (es) 1995-01-31
IE890157L (en) 1989-07-20
PH25605A (en) 1991-08-08
BG60530B2 (bg) 1995-07-28
AU2864489A (en) 1989-07-20
YU11789A (en) 1991-04-30
EP0325279A1 (de) 1989-07-26
NO890239L (no) 1989-07-21
NO175429B (no) 1994-07-04
AU622139B2 (en) 1992-04-02
DK19789D0 (da) 1989-01-17
FI890283A0 (fi) 1989-01-19
ATE74350T1 (de) 1992-04-15
JPH0764806B2 (ja) 1995-07-12
DK169945B1 (da) 1995-04-10
ZA8923B (en) 1989-09-27
NO890239D0 (no) 1989-01-19
EP0325279B1 (de) 1992-04-01
PT89486A (pt) 1989-10-04
IE60921B1 (en) 1994-09-07
KR890011838A (ko) 1989-08-22
FI890283A (fi) 1989-07-21
JPH029861A (ja) 1990-01-12
HU201007B (en) 1990-09-28
YU47298B (sh) 1995-01-31
PT89486B (pt) 1993-12-31
DE58901056D1 (de) 1992-05-07

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

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