DE1518222A1 - Phenylalkylaminoguanidine - Google Patents

Phenylalkylaminoguanidine

Info

Publication number
DE1518222A1
DE1518222A1 DE19651518222 DE1518222A DE1518222A1 DE 1518222 A1 DE1518222 A1 DE 1518222A1 DE 19651518222 DE19651518222 DE 19651518222 DE 1518222 A DE1518222 A DE 1518222A DE 1518222 A1 DE1518222 A1 DE 1518222A1
Authority
DE
Germany
Prior art keywords
acid addition
addition salts
derivative according
formula
ethylaminoguanidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE19651518222
Other languages
German (de)
English (en)
Inventor
Bream John B
White Trevor G
Picard Dr Claude W
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wander AG
Original Assignee
Wander AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wander AG filed Critical Wander AG
Publication of DE1518222A1 publication Critical patent/DE1518222A1/de
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
    • C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE19651518222 1964-05-05 1965-04-27 Phenylalkylaminoguanidine Pending DE1518222A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH585464A CH448057A (de) 1964-05-05 1964-05-05 Verfahren zur Herstellung von Phenylalkylaminoguanidinen

Publications (1)

Publication Number Publication Date
DE1518222A1 true DE1518222A1 (de) 1969-06-12

Family

ID=4300408

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19651518222 Pending DE1518222A1 (de) 1964-05-05 1965-04-27 Phenylalkylaminoguanidine

Country Status (15)

Country Link
JP (1) JPS4842627B1 (fr)
AT (3) AT255434B (fr)
BE (1) BE663481A (fr)
BR (1) BR6569419D0 (fr)
CH (3) CH491873A (fr)
CS (1) CS151461B2 (fr)
DE (1) DE1518222A1 (fr)
DK (2) DK107288C (fr)
ES (1) ES312384A1 (fr)
FI (1) FI42316B (fr)
FR (1) FR4399M (fr)
GB (1) GB1096348A (fr)
IL (1) IL23443A (fr)
NL (1) NL6505684A (fr)
SE (2) SE371640B (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445339A1 (de) * 1983-12-12 1985-06-13 Biogál Gyógyszergyár, Debrecen 3,3-disubstituierte 1-(phenylamino)-guanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0325936A2 (fr) * 1988-01-16 1989-08-02 Ono Pharmaceutical Co., Ltd. Dérivés d'aminoguanidine et agents inhibiteurs pour la réaction de maillard les contenant comme ingrédient actives
WO1998023565A2 (fr) * 1996-11-26 1998-06-04 3-Dimensional Pharmaceuticals, Inc. Aminoguanidines et alcoxyguanidines utilisees en tant qu'inhibiteurs de proteases
US6635637B2 (en) 2000-08-04 2003-10-21 Dimensional Pharmaceuticals, Inc. Cyclic oxyguanidine protease inhibitors

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR200F (fr) * 1965-11-15
US3541218A (en) * 1969-06-18 1970-11-17 Lilly Co Eli Omicron-fluorobenzylaminoguanidine for diabetes
JPS5051717U (fr) * 1973-09-06 1975-05-19
JPS5391735U (fr) * 1976-12-27 1978-07-27
JPS54121027U (fr) * 1978-02-13 1979-08-24
JPS5625169A (en) * 1979-06-01 1981-03-10 Wellcome Found Triazine derivative
JPS5625170A (en) * 1979-06-01 1981-03-10 Wellcome Found Triazine derivative
FR2549049B1 (fr) * 1983-07-13 1986-06-20 Chauvin Blache Lab Nouvelles amidines, leur procede de preparation et leur application therapeutique
CA2250426C (fr) * 1996-03-29 2006-05-02 3-Dimensional Pharmaceuticals, Inc. Amidinohydrazones utilises en qualite d'inhibiteurs de protease

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3445339A1 (de) * 1983-12-12 1985-06-13 Biogál Gyógyszergyár, Debrecen 3,3-disubstituierte 1-(phenylamino)-guanidinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
EP0325936A2 (fr) * 1988-01-16 1989-08-02 Ono Pharmaceutical Co., Ltd. Dérivés d'aminoguanidine et agents inhibiteurs pour la réaction de maillard les contenant comme ingrédient actives
EP0325936A3 (fr) * 1988-01-16 1990-01-17 Ono Pharmaceutical Co., Ltd. Dérivés d'aminoguanidine et agents inhibiteurs pour la réaction de maillard les contenant comme ingrédient actives
WO1998023565A2 (fr) * 1996-11-26 1998-06-04 3-Dimensional Pharmaceuticals, Inc. Aminoguanidines et alcoxyguanidines utilisees en tant qu'inhibiteurs de proteases
WO1998023565A3 (fr) * 1996-11-26 1998-07-30 Dimensional Pharm Inc Aminoguanidines et alcoxyguanidines utilisees en tant qu'inhibiteurs de proteases
US6235778B1 (en) 1996-11-26 2001-05-22 3-Dimensional Pharmaceuticals, Inc. Aminoguanidines and alkoxyguanidines as protease inhibitors
US6518310B2 (en) 1996-11-26 2003-02-11 3-Dimensional Pharmaceuticals, Inc. Aminoguanidines and alkoxyguanidines as protease inhibitors
US6638931B1 (en) 1996-11-26 2003-10-28 3-Dimensional Pharmaceuticals, Inc. Aminoguanidines and alkoxyguanidines as protease inhibitors
US6706765B2 (en) 1996-11-26 2004-03-16 3-Dimensional Pharmaceuticals, Inc. Aminoguanidines and alkoxyguanidines as protease inhibitors
US6730783B2 (en) 1996-11-26 2004-05-04 3-Dimensional Pharmaceuticals, Inc. Process for preparing aminoguanidines and alkoxyguanidines as protease inhibitors
US6635637B2 (en) 2000-08-04 2003-10-21 Dimensional Pharmaceuticals, Inc. Cyclic oxyguanidine protease inhibitors

Also Published As

Publication number Publication date
CH511216A (de) 1971-08-15
JPS4842627B1 (fr) 1973-12-13
BE663481A (fr)
AT255434B (de) 1967-07-10
GB1096348A (en) 1967-12-29
AT255433B (de) 1967-07-10
CH448057A (de) 1967-12-15
FI42316B (fr) 1970-03-31
DK107288C (da) 1967-05-16
AT255432B (de) 1967-07-10
FR4399M (fr) 1966-09-05
BR6569419D0 (pt) 1973-08-02
ES312384A1 (es) 1966-03-01
DK111887B (da) 1968-10-21
NL6505684A (fr) 1965-11-08
SE317057B (fr) 1969-11-10
IL23443A (en) 1968-09-26
CS151461B2 (fr) 1973-10-19
CH491873A (de) 1970-06-15
SE371640B (fr) 1974-11-25

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