CH649998A5 - Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff. - Google Patents

Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff. Download PDF

Info

Publication number
CH649998A5
CH649998A5 CH4772/82A CH477282A CH649998A5 CH 649998 A5 CH649998 A5 CH 649998A5 CH 4772/82 A CH4772/82 A CH 4772/82A CH 477282 A CH477282 A CH 477282A CH 649998 A5 CH649998 A5 CH 649998A5
Authority
CH
Switzerland
Prior art keywords
formula
compounds
ergol
derivatives
production
Prior art date
Application number
CH4772/82A
Other languages
German (de)
English (en)
Inventor
Peter Dr Gull
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Priority to CH4772/82A priority Critical patent/CH649998A5/de
Priority to DE19833327705 priority patent/DE3327705A1/de
Priority to FI832789A priority patent/FI73679C/fi
Priority to FR8313018A priority patent/FR2531433B1/fr
Priority to GB08321222A priority patent/GB2125041B/en
Priority to BE1/10847A priority patent/BE897473A/fr
Priority to NL8302776A priority patent/NL8302776A/nl
Priority to ES524815A priority patent/ES8502992A1/es
Priority to AT0286383A priority patent/AT383125B/de
Priority to PT77168A priority patent/PT77168B/pt
Priority to GR72165A priority patent/GR78923B/el
Priority to HU832798A priority patent/HU187600B/hu
Priority to AU17672/83A priority patent/AU563736B2/en
Priority to DK361983A priority patent/DK361983A/da
Priority to JP58144843A priority patent/JPS5948480A/ja
Priority to IL69450A priority patent/IL69450A/xx
Priority to NZ205181A priority patent/NZ205181A/en
Priority to CA000434064A priority patent/CA1215972A/en
Priority to SE8304315A priority patent/SE8304315L/xx
Priority to IT22490/83A priority patent/IT1168961B/it
Priority to PH29378A priority patent/PH20385A/en
Priority to ZA835850A priority patent/ZA835850B/xx
Publication of CH649998A5 publication Critical patent/CH649998A5/de
Priority to MY166/87A priority patent/MY8700166A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
CH4772/82A 1982-08-09 1982-08-09 Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff. CH649998A5 (de)

Priority Applications (23)

Application Number Priority Date Filing Date Title
CH4772/82A CH649998A5 (de) 1982-08-09 1982-08-09 Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
DE19833327705 DE3327705A1 (de) 1982-08-09 1983-08-01 Mutterkornalkaloide, ihre herstellung und verwendung
FI832789A FI73679C (fi) 1982-08-09 1983-08-02 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara ergolinderivat och mellanprodukt foer anvaendning vid foerfarandet.
FR8313018A FR2531433B1 (fr) 1982-08-09 1983-08-04 Nouveaux alcaloides de l'ergot de seigle, leur preparation et leur utilisation comme medicaments
GB08321222A GB2125041B (en) 1982-08-09 1983-08-05 Ergot alkaloids
BE1/10847A BE897473A (fr) 1982-08-09 1983-08-05 Nouveaux alcaloides de l'ergot de seigle leur preparation et leur utilisation comme medicaments
NL8302776A NL8302776A (nl) 1982-08-09 1983-08-05 Moederkoornalkaloiden en werkwijzen voor hun bereiding en toepassing.
HU832798A HU187600B (en) 1982-08-09 1983-08-08 Process for preparing 2-methyl-9,10-didehydro-ergolines
NZ205181A NZ205181A (en) 1982-08-09 1983-08-08 2-methyl-lyserg-8-yl ethers and thioethers,a method for their preparation and pharmaceutical compositions which contain them
PT77168A PT77168B (en) 1982-08-09 1983-08-08 Process for the preparation of ergot alkaloids
GR72165A GR78923B (da) 1982-08-09 1983-08-08
ES524815A ES8502992A1 (es) 1982-08-09 1983-08-08 Procedimiento para la preparacion de un (tio)-eter de 2-metil-liserg-8-ilo
AU17672/83A AU563736B2 (en) 1982-08-09 1983-08-08 Lysergic acid derivatives
DK361983A DK361983A (da) 1982-08-09 1983-08-08 Fremgangsmaade til fremstilling af meldroejealkaloider
JP58144843A JPS5948480A (ja) 1982-08-09 1983-08-08 麦角アルカロイド
IL69450A IL69450A (en) 1982-08-09 1983-08-08 2-methyl-8-lysergyl aryl ethers and thioethers,their production and pharmaceutical compositions containing them
AT0286383A AT383125B (de) 1982-08-09 1983-08-08 Verfahren zur herstellung von neuen mutterkornalkaloiden
CA000434064A CA1215972A (en) 1982-08-09 1983-08-08 Ergot alkaloids
SE8304315A SE8304315L (sv) 1982-08-09 1983-08-08 Mjoldrygealkaloider, deras framstellning och anvendning
IT22490/83A IT1168961B (it) 1982-08-09 1983-08-09 Alcaloidi della segale cornuta,loro preparazione e loro impiego come medicamenti
PH29378A PH20385A (en) 1982-08-09 1983-08-09 Ergot alkaloids, compositions containing the same and method of use thereof
ZA835850A ZA835850B (en) 1982-08-09 1983-08-09 Ergot alcaloids
MY166/87A MY8700166A (en) 1982-08-09 1987-12-30 Ergot alkaloids

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4772/82A CH649998A5 (de) 1982-08-09 1982-08-09 Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.

Publications (1)

Publication Number Publication Date
CH649998A5 true CH649998A5 (de) 1985-06-28

Family

ID=4282273

Family Applications (1)

Application Number Title Priority Date Filing Date
CH4772/82A CH649998A5 (de) 1982-08-09 1982-08-09 Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.

Country Status (23)

Country Link
JP (1) JPS5948480A (da)
AT (1) AT383125B (da)
AU (1) AU563736B2 (da)
BE (1) BE897473A (da)
CA (1) CA1215972A (da)
CH (1) CH649998A5 (da)
DE (1) DE3327705A1 (da)
DK (1) DK361983A (da)
ES (1) ES8502992A1 (da)
FI (1) FI73679C (da)
FR (1) FR2531433B1 (da)
GB (1) GB2125041B (da)
GR (1) GR78923B (da)
HU (1) HU187600B (da)
IL (1) IL69450A (da)
IT (1) IT1168961B (da)
MY (1) MY8700166A (da)
NL (1) NL8302776A (da)
NZ (1) NZ205181A (da)
PH (1) PH20385A (da)
PT (1) PT77168B (da)
SE (1) SE8304315L (da)
ZA (1) ZA835850B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
HU193782B (en) * 1985-06-21 1987-11-30 Richter Gedeon Vegyeszet Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof
FR2589734B1 (fr) * 1985-11-13 1988-09-02 Roussel Uclaf Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
US4798834A (en) * 1987-08-31 1989-01-17 Eli Lilly And Company Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement
DE3913756A1 (de) * 1989-04-21 1990-10-25 Schering Ag 8(beta)-substituierte ergoline, verfahren zu ihrer herstellung und ihre verwendung
DE10212564B4 (de) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41533B1 (en) * 1974-03-14 1980-01-30 Sandoz Ltd Thiomethyl ergolene derivatives
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity

Also Published As

Publication number Publication date
BE897473A (fr) 1984-02-06
DE3327705A1 (de) 1984-02-09
DK361983A (da) 1984-02-10
DK361983D0 (da) 1983-08-08
AU1767283A (en) 1984-02-16
FI73679B (fi) 1987-07-31
IT8322490A0 (it) 1983-08-09
ZA835850B (en) 1985-03-27
SE8304315L (sv) 1984-02-10
IT1168961B (it) 1987-05-20
IL69450A0 (en) 1983-11-30
HU187600B (en) 1986-01-28
PT77168A (en) 1983-09-01
FI832789A (fi) 1984-02-10
MY8700166A (en) 1987-12-31
PH20385A (en) 1986-12-08
ES524815A0 (es) 1985-02-01
ATA286383A (de) 1986-10-15
ES8502992A1 (es) 1985-02-01
SE8304315D0 (sv) 1983-08-08
CA1215972A (en) 1986-12-30
NZ205181A (en) 1986-07-11
FR2531433B1 (fr) 1985-10-18
FI832789A0 (fi) 1983-08-02
GB2125041B (en) 1986-04-23
FI73679C (fi) 1987-11-09
GR78923B (da) 1984-10-02
GB8321222D0 (en) 1983-09-07
FR2531433A1 (fr) 1984-02-10
NL8302776A (nl) 1984-03-01
AU563736B2 (en) 1987-07-23
JPS5948480A (ja) 1984-03-19
IL69450A (en) 1986-10-31
GB2125041A (en) 1984-02-29
AT383125B (de) 1987-05-25
PT77168B (en) 1986-03-27

Similar Documents

Publication Publication Date Title
EP0189370A2 (de) Spiro-dioxolane, -dithiolane und -oxothiolane
EP0161599A2 (de) Neue Benzazepinderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zu ihrer Herstellung
DE2602643A1 (de) 1,2-benzisothiazolinone-3, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
DE2523103A1 (de) Neue propargyl-2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
EP0665228B1 (de) Neue 3-Phenylsulfonyl-3,7-diazabicyclo(3,3,1)nonan-Verbindungen enthaltende Arzneimittel
CH649998A5 (de) Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.
DE2535599C2 (de) Substituierte Zimtsäureamide, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitungen, welche diese Verbindungen enthalten
AT391316B (de) Neue thienyloxy-alkylamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE2427272C3 (de) 1-(2-(β-Naphthyloxy)-äthyl)-3-methyl -pyrazolon-(5), Verfahren sowie Verwendung als Antithrombotikum
DE69512104T2 (de) Substituierte Sulfonamide, Verfahren zu deren Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
DE2549568A1 (de) 2,6-dimethyl-3-methoxycarbonyl-4- (2'-nitrophenyl)-1,4-dihydropyridin-5- carbonsaeureisobutylester, mehrere verfahren zu seiner herstellung sowie seine verwendung als coronartherapeutikum
DE2716172C2 (de) Bis(6-[(hexahydro-1H-azepin-1-yl)-methylenamino]-penicillanoyloxy)-methan, seine Herstellung und dieses enthaltendes Arzneimittel
DE1934392C3 (de) Neue 2-Pyridylthioamide und Verfahren zu ihrer Herstellung
DE1695812B2 (de) Dibenzo [cfl -1,2-thiazepin-derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zubereitung
DE3414801A1 (de) 4-(nitrophenyl)-tetrahydropyridine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
CH657366A5 (en) Ergot alkaloids, their preparation and use
DE2520131A1 (de) Stickstoffhaltige polycyclische verbindungen und verfahren zu deren herstellung
EP1270576B1 (de) 3-Phenyl-3,7-diazabicyclo(3,3,1)nonan-Verbindungen sowie Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2508251C2 (de) Derivate des Indols, Verfahren zu deren Herstellung sowie diese enthaltende Arzneimittel
DE2656227C2 (de) Basisch alkylierte Diphenyldisulfid-2,2'-biscarbonsäureamide, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel
DE2430510C3 (de) 16,17-Dihydroapovincaminsäureamide, Verfahren zu deren Herstellung und Arzneimittel, welche diese Verbingungen enthalten
DE3107599C2 (de) N-Cyan-N'-methyl-N"-{2-[(5-methylthio-imidazol-4-yl)-methylthio]-äthyl}-guanidin, Verfahren zu seiner Herstellung und diese Verbindung enthaltende Arzneimittel
DE2530768C3 (de) PhenoxyaUcylaminpyridyläther, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Präparate
EP0006451A1 (de) Neue Imidazo(1,2-a)imidazole, deren Säureadditionssalze, diese enthaltende Arzneimittel und Verfahren zu deren Herstellung
DD150060A5 (de) Verfahren zur herstellung von neuen phenthiazin-derivaten

Legal Events

Date Code Title Description
PL Patent ceased