BE897473A - Nouveaux alcaloides de l'ergot de seigle leur preparation et leur utilisation comme medicaments - Google Patents

Nouveaux alcaloides de l'ergot de seigle leur preparation et leur utilisation comme medicaments Download PDF

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Publication number
BE897473A
BE897473A BE1/10847A BE1010847A BE897473A BE 897473 A BE897473 A BE 897473A BE 1/10847 A BE1/10847 A BE 1/10847A BE 1010847 A BE1010847 A BE 1010847A BE 897473 A BE897473 A BE 897473A
Authority
BE
Belgium
Prior art keywords
compound
group
formula
addition salt
compounds
Prior art date
Application number
BE1/10847A
Other languages
English (en)
French (fr)
Original Assignee
Sandoz Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Sa filed Critical Sandoz Sa
Publication of BE897473A publication Critical patent/BE897473A/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/02—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with hydrocarbon or substituted hydrocarbon radicals, attached in position 8
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
BE1/10847A 1982-08-09 1983-08-05 Nouveaux alcaloides de l'ergot de seigle leur preparation et leur utilisation comme medicaments BE897473A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH4772/82A CH649998A5 (de) 1982-08-09 1982-08-09 Ergolinderivate, ein verfahren zu ihrer herstellung und heilmittel, enthaltend diese ergolinderivate als wirkstoff.

Publications (1)

Publication Number Publication Date
BE897473A true BE897473A (fr) 1984-02-06

Family

ID=4282273

Family Applications (1)

Application Number Title Priority Date Filing Date
BE1/10847A BE897473A (fr) 1982-08-09 1983-08-05 Nouveaux alcaloides de l'ergot de seigle leur preparation et leur utilisation comme medicaments

Country Status (23)

Country Link
JP (1) JPS5948480A (da)
AT (1) AT383125B (da)
AU (1) AU563736B2 (da)
BE (1) BE897473A (da)
CA (1) CA1215972A (da)
CH (1) CH649998A5 (da)
DE (1) DE3327705A1 (da)
DK (1) DK361983A (da)
ES (1) ES8502992A1 (da)
FI (1) FI73679C (da)
FR (1) FR2531433B1 (da)
GB (1) GB2125041B (da)
GR (1) GR78923B (da)
HU (1) HU187600B (da)
IL (1) IL69450A (da)
IT (1) IT1168961B (da)
MY (1) MY8700166A (da)
NL (1) NL8302776A (da)
NZ (1) NZ205181A (da)
PH (1) PH20385A (da)
PT (1) PT77168B (da)
SE (1) SE8304315L (da)
ZA (1) ZA835850B (da)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675322A (en) * 1984-12-10 1987-06-23 Eli Lilly And Company 1-Substituted-6-n-propyl-8β-methylthio-methylergolines
HU193782B (en) * 1985-06-21 1987-11-30 Richter Gedeon Vegyeszet Process for producing 2-halogeno-nicergoline derivatives and acid additional salts thereof
FR2589734B1 (fr) * 1985-11-13 1988-09-02 Roussel Uclaf Utilisation de derives de l'ergoline a l'obtention d'un medicament a visee geriatrique
US4798834A (en) * 1987-08-31 1989-01-17 Eli Lilly And Company Optionally substituted (3β-9,10-didehydro-2,3-dihydro ergoline as serotonergic function enhancement
DE3913756A1 (de) * 1989-04-21 1990-10-25 Schering Ag 8(beta)-substituierte ergoline, verfahren zu ihrer herstellung und ihre verwendung
DE10212564B4 (de) * 2002-03-12 2007-04-19 Neurobiotec Gmbh 1-Allyl-ergotalkaloid-Derivate und ihre Verwendung zur Prophylaxe und Therapie von Migräne

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE41533B1 (en) * 1974-03-14 1980-01-30 Sandoz Ltd Thiomethyl ergolene derivatives
US3901894A (en) * 1974-06-06 1975-08-26 Lilly Co Eli 8-thiomethylergolines
US3959288A (en) * 1974-12-13 1976-05-25 Eli Lilly And Company 8-Oxymethylergolines and process therefor
US4166182A (en) * 1978-02-08 1979-08-28 Eli Lilly And Company 6-n-propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
US4382940A (en) * 1979-12-06 1983-05-10 Farmitalia Carlo Erba S.P.A. Ercoline derivatives and therapeutic compositions having CNS affecting activity

Also Published As

Publication number Publication date
DE3327705A1 (de) 1984-02-09
DK361983A (da) 1984-02-10
DK361983D0 (da) 1983-08-08
AU1767283A (en) 1984-02-16
FI73679B (fi) 1987-07-31
IT8322490A0 (it) 1983-08-09
ZA835850B (en) 1985-03-27
SE8304315L (sv) 1984-02-10
CH649998A5 (de) 1985-06-28
IT1168961B (it) 1987-05-20
IL69450A0 (en) 1983-11-30
HU187600B (en) 1986-01-28
PT77168A (en) 1983-09-01
FI832789A (fi) 1984-02-10
MY8700166A (en) 1987-12-31
PH20385A (en) 1986-12-08
ES524815A0 (es) 1985-02-01
ATA286383A (de) 1986-10-15
ES8502992A1 (es) 1985-02-01
SE8304315D0 (sv) 1983-08-08
CA1215972A (en) 1986-12-30
NZ205181A (en) 1986-07-11
FR2531433B1 (fr) 1985-10-18
FI832789A0 (fi) 1983-08-02
GB2125041B (en) 1986-04-23
FI73679C (fi) 1987-11-09
GR78923B (da) 1984-10-02
GB8321222D0 (en) 1983-09-07
FR2531433A1 (fr) 1984-02-10
NL8302776A (nl) 1984-03-01
AU563736B2 (en) 1987-07-23
JPS5948480A (ja) 1984-03-19
IL69450A (en) 1986-10-31
GB2125041A (en) 1984-02-29
AT383125B (de) 1987-05-25
PT77168B (en) 1986-03-27

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: SANDOZ S.A.

Effective date: 19870831