CA2362306A1 - Chemical compounds - Google Patents

Chemical compounds Download PDF

Info

Publication number
CA2362306A1
CA2362306A1 CA002362306A CA2362306A CA2362306A1 CA 2362306 A1 CA2362306 A1 CA 2362306A1 CA 002362306 A CA002362306 A CA 002362306A CA 2362306 A CA2362306 A CA 2362306A CA 2362306 A1 CA2362306 A1 CA 2362306A1
Authority
CA
Canada
Prior art keywords
glucopyranose
benzylidene
deoxy
hydroxybenzylidene
galactopyranose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002362306A
Other languages
English (en)
French (fr)
Inventor
Camilla Bruno Dunsaed
Geir Sagvolden
Bernt Borretzen
Vidar Moen
Rolf Olaf Larsen
Erik Olai Pettersen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Norsk Hydro ASA
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2362306A1 publication Critical patent/CA2362306A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H9/00—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical
    • C07H9/02—Compounds containing a hetero ring sharing at least two hetero atoms with a saccharide radical the hetero ring containing only oxygen as ring hetero atoms
    • C07H9/04—Cyclic acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Pain & Pain Management (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
CA002362306A 1999-02-19 2000-02-18 Chemical compounds Abandoned CA2362306A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO990814A NO309305B1 (no) 1999-02-19 1999-02-19 Anvendelse av benzaldehydderivater ved fremstilling av farmasöytiske preparater for forebygging og/eller behandling av kreft, samt visse nye benzaldehydderivater
NO19990814 1999-02-19
PCT/NO2000/000059 WO2000048609A1 (en) 1999-02-19 2000-02-18 Chemical compounds

Publications (1)

Publication Number Publication Date
CA2362306A1 true CA2362306A1 (en) 2000-08-24

Family

ID=19902986

Family Applications (2)

Application Number Title Priority Date Filing Date
CA002363670A Abandoned CA2363670A1 (en) 1999-02-19 2000-02-18 Chemical compounds
CA002362306A Abandoned CA2362306A1 (en) 1999-02-19 2000-02-18 Chemical compounds

Family Applications Before (1)

Application Number Title Priority Date Filing Date
CA002363670A Abandoned CA2363670A1 (en) 1999-02-19 2000-02-18 Chemical compounds

Country Status (15)

Country Link
EP (2) EP1150690A1 (cs)
JP (2) JP2002537263A (cs)
CN (2) CN1347323A (cs)
AU (2) AU2834200A (cs)
BR (2) BR0008302A (cs)
CA (2) CA2363670A1 (cs)
CZ (2) CZ20012966A3 (cs)
HU (2) HUP0105281A2 (cs)
IL (2) IL144896A0 (cs)
MX (2) MXPA01008347A (cs)
NO (1) NO309305B1 (cs)
PL (2) PL350519A1 (cs)
RU (2) RU2001123124A (cs)
SK (2) SK11612001A3 (cs)
WO (2) WO2000048609A1 (cs)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002096921A1 (fr) * 2001-05-30 2002-12-05 Nisshin Seifun Group Inc. Nouveau derive glucose induisant l'apoptose, procede de production et utilisation comme medicament
DE10261807A1 (de) * 2002-12-19 2004-07-01 Turicum Drug Development Ag Deuterierte Catecholaminderivate sowie diese Verbindungen enthaltende Arzneimittel
TWI394750B (zh) * 2005-07-26 2013-05-01 Takeda Gmbh 同位素取代之質子泵抑制劑
AR054583A1 (es) * 2005-07-26 2007-06-27 Altana Pharma Ag Pantoprazol isotopicamente sustituido
CA2624179A1 (en) * 2005-10-06 2007-04-12 Auspex Pharmaceuticals, Inc. Deuterated inhibitors of gastric h+, k+-atpase with enhanced therapeutic properties
CN101157711B (zh) * 2007-09-28 2010-12-08 西安交通大学 一种具有抗肿瘤活性的化合物及其用途
CN102046180A (zh) * 2008-04-03 2011-05-04 同源3公司 用于免疫治疗的组合物和方法
CN101735284B (zh) * 2008-11-24 2012-05-23 上海医药工业研究院 一种4,6-o-苄叉-d-吡喃葡萄糖的制备方法
IL305990A (en) 2013-12-03 2023-11-01 Intra Cellular Therapies Inc Compressed gamma-carboline heterocyclic compounds are modified for use in the treatment of type I and/or type II bipolar disorders
ES2961843T3 (es) * 2014-04-04 2024-03-14 Intra Cellular Therapies Inc Gamma-carbolinas condensadas con heterociclo deuteradas como antagonistas de los receptores de 5-HT2A
JP6898072B2 (ja) * 2015-08-27 2021-07-07 秀行 佐谷 １４−３−３タンパク質活性調節剤
AU2017238842B2 (en) 2016-03-25 2019-06-20 Intra-Cellular Therapies, Inc. Organic compounds
WO2018071233A1 (en) 2016-10-12 2018-04-19 Intra-Cellular Therapies, Inc. Amorphous solid dispersions
IL268970B2 (en) 2017-03-24 2023-12-01 Intra Cellular Therapies Inc Oral preparations of heterocyclic gamma carboline derivatives fused for absorption through mucous membranes
KR20210052472A (ko) 2018-08-31 2021-05-10 인트라-셀룰라 써래피스, 인코퍼레이티드. 신규한 방법
CN112584837A (zh) 2018-08-31 2021-03-30 细胞内治疗公司 新方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB811510A (en) * 1954-12-20 1959-04-08 Gyogyszeripari Ki New nitrogen-containing derivatives of polyhydroxy compounds and process for the preparation thereof
JPS6112623A (ja) * 1984-06-28 1986-01-21 Kaken Pharmaceut Co Ltd エンケフアリナ−ゼ阻害剤
JPS6256423A (ja) * 1985-09-06 1987-03-12 Kaken Pharmaceut Co Ltd 悪液質治療改善剤
GB8705780D0 (en) * 1987-03-11 1987-04-15 Norsk Hydro As Anticancer compounds
JPH07145191A (ja) * 1993-11-24 1995-06-06 Japan Tobacco Inc ガラクトシルホスフォネート誘導体

Also Published As

Publication number Publication date
NO990814L (no) 2000-08-21
MXPA01008347A (es) 2004-03-10
BR0008302A (pt) 2002-08-27
NO309305B1 (no) 2001-01-15
EP1150689A1 (en) 2001-11-07
RU2001123124A (ru) 2004-02-20
SK11602001A3 (sk) 2002-02-05
AU2834200A (en) 2000-09-04
CN1347323A (zh) 2002-05-01
HUP0105281A2 (hu) 2002-05-29
CZ20012965A3 (cs) 2002-03-13
JP2002537263A (ja) 2002-11-05
NO990814D0 (no) 1999-02-19
HUP0105280A2 (hu) 2002-04-29
EP1150690A1 (en) 2001-11-07
BR0008297A (pt) 2002-05-28
JP2002537264A (ja) 2002-11-05
CA2363670A1 (en) 2000-08-24
IL144895A0 (en) 2002-06-30
AU2834100A (en) 2000-09-04
WO2000048610A1 (en) 2000-08-24
CN1347322A (zh) 2002-05-01
PL350519A1 (en) 2002-12-16
RU2001123035A (ru) 2004-03-20
SK11612001A3 (sk) 2002-04-04
IL144896A0 (en) 2002-06-30
WO2000048609A1 (en) 2000-08-24
PL350520A1 (en) 2002-12-16
CZ20012966A3 (cs) 2002-03-13
MXPA01008346A (es) 2003-06-06

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Legal Events

Date Code Title Description
FZDE Discontinued