ZA200806226B - 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrim-idines as jak 2 modulators and methods of use - Google Patents

4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrim-idines as jak 2 modulators and methods of use

Info

Publication number
ZA200806226B
ZA200806226B ZA200806226A ZA200806226A ZA200806226B ZA 200806226 B ZA200806226 B ZA 200806226B ZA 200806226 A ZA200806226 A ZA 200806226A ZA 200806226 A ZA200806226 A ZA 200806226A ZA 200806226 B ZA200806226 B ZA 200806226B
Authority
ZA
South Africa
Prior art keywords
aryl
idines
pyrim
jak
pyrimidines
Prior art date
Application number
ZA200806226A
Other languages
English (en)
Inventor
Mann Grace
Brown S David
Du Hongwang
Adam A Galan
Johnson Henry William Beecroft
Kim Byung Gyu
Lee Matthew Sangyup
Noguchi Robin Tammiev
Shi Xian
Aay Naing
Chan Wai Ki Vicky
Epshteyn Sergey
Hunh Tai Phat
Kane Brian
Koltun Elena
Gary L Lewis
Pack Michael
Woolfrey John
Arcalas Arlyn
Chen Jeff
Forsyth Timothy Patrick
Ibrahim Mohamed Abdulkader
Kearney Patrick
Leahy James William
Lisa E Meyr
Ridgway Brian Hugh
Zhou Peiwen
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of ZA200806226B publication Critical patent/ZA200806226B/xx

Links

ZA200806226A 2006-01-30 2008-07-17 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrim-idines as jak 2 modulators and methods of use ZA200806226B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76342606P 2006-01-30 2006-01-30

Publications (1)

Publication Number Publication Date
ZA200806226B true ZA200806226B (en) 2009-09-30

Family

ID=40631426

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200806226A ZA200806226B (en) 2006-01-30 2008-07-17 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrim-idines as jak 2 modulators and methods of use

Country Status (2)

Country Link
CN (1) CN101421250A (xx)
ZA (1) ZA200806226B (xx)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2616458T3 (es) * 2011-04-19 2017-06-13 Nerviano Medical Sciences S.R.L. Pirimidil pirroles sustituidos activos como inhibidores de quinasas
KR102334260B1 (ko) * 2013-03-14 2021-12-02 스미토모 다이니폰 파마 온콜로지, 인크. Ｊａｋ2 및 ａｌｋ2 억제제 및 이들의 사용 방법
CN105377835B (zh) * 2013-07-11 2018-08-17 贝达药业股份有限公司 酪氨酸蛋白激酶调节剂及其应用方法
CN105399685B (zh) 2014-09-16 2018-05-22 深圳微芯生物科技有限责任公司 作为选择性jak3和/或jak1激酶抑制剂的芳杂环化合物的制备方法及其应用
CN105399686B (zh) * 2014-09-16 2018-05-22 深圳微芯生物科技有限责任公司 嘧啶衍生物、其制备方法及其应用
CN107793417B (zh) * 2016-09-05 2020-06-09 复旦大学 吡咯并[2,3-d]嘧啶类化合物及其盐，及制备方法和药用用途
WO2018067704A1 (en) * 2016-10-04 2018-04-12 Enanta Pharmaceuticals, Inc. Isoxazole analogs as fxr agonists and methods of use thereof
CN115925693A (zh) * 2017-01-17 2023-04-07 阿斯利康(瑞典)有限公司 Jak1选择性抑制剂
CN108794458A (zh) * 2018-07-31 2018-11-13 湖北欣瑞康医药科技有限公司 一种芳基取代嘧啶胺酰基化衍生物的制备方法
CN110305140B (zh) 2019-07-30 2020-08-04 上海勋和医药科技有限公司 二氢吡咯并嘧啶类选择性jak2抑制剂
CN112142675B (zh) * 2020-10-09 2021-11-30 嘉兴特科罗生物科技有限公司 一种作为jak激酶抑制剂的小分子化合物及其用途
CN112375042A (zh) * 2020-10-27 2021-02-19 安徽医科大学 三甲氧基苯乙烯基六元环类和吡唑并嘧啶类化合物、制剂及其制备与应用
CN113735859A (zh) * 2021-08-12 2021-12-03 安徽医科大学 一种激酶抑制剂

Also Published As

Publication number Publication date
CN101421250A (zh) 2009-04-29

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