ZA200806226B - 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrim-idines as jak 2 modulators and methods of use - Google Patents

4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrim-idines as jak 2 modulators and methods of use

Info

Publication number
ZA200806226B
ZA200806226B ZA200806226A ZA200806226A ZA200806226B ZA 200806226 B ZA200806226 B ZA 200806226B ZA 200806226 A ZA200806226 A ZA 200806226A ZA 200806226 A ZA200806226 A ZA 200806226A ZA 200806226 B ZA200806226 B ZA 200806226B
Authority
ZA
South Africa
Prior art keywords
aryl
idines
pyrim
jak
pyrimidines
Prior art date
Application number
ZA200806226A
Inventor
Mann Grace
Brown S David
Du Hongwang
Adam A Galan
Johnson Henry William Beecroft
Kim Byung Gyu
Lee Matthew Sangyup
Noguchi Robin Tammiev
Shi Xian
Aay Naing
Chan Wai Ki Vicky
Epshteyn Sergey
Hunh Tai Phat
Kane Brian
Koltun Elena
Gary L Lewis
Pack Michael
Woolfrey John
Arcalas Arlyn
Chen Jeff
Forsyth Timothy Patrick
Ibrahim Mohamed Abdulkader
Kearney Patrick
Leahy James William
Lisa E Meyr
Ridgway Brian Hugh
Zhou Peiwen
Original Assignee
Exelixis Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exelixis Inc filed Critical Exelixis Inc
Publication of ZA200806226B publication Critical patent/ZA200806226B/en

Links

ZA200806226A 2006-01-30 2008-07-17 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrim-idines as jak 2 modulators and methods of use ZA200806226B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US76342606P 2006-01-30 2006-01-30

Publications (1)

Publication Number Publication Date
ZA200806226B true ZA200806226B (en) 2009-09-30

Family

ID=40631426

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200806226A ZA200806226B (en) 2006-01-30 2008-07-17 4-aryl-2-amino-pyrimidines or 4-aryl-2-aminoalkyl-pyrim-idines as jak 2 modulators and methods of use

Country Status (2)

Country Link
CN (1) CN101421250A (en)
ZA (1) ZA200806226B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112013026137B1 (en) * 2011-04-19 2020-12-01 Nerviano Medical Sciences S.R.L substituted pyrimidinyl-pyrroles as kinase inhibitors
ES2738493T3 (en) * 2013-03-14 2020-01-23 Tolero Pharmaceuticals Inc JAK2 and ALK2 inhibitors and methods for their use
CN105377835B (en) * 2013-07-11 2018-08-17 贝达药业股份有限公司 Tyrosine protein kinase conditioning agent and its application process
CN105399685B (en) * 2014-09-16 2018-05-22 深圳微芯生物科技有限责任公司 The alternatively preparation method and applications of the heteroaromatic compounds of property JAK3 and/or JAK1 kinase inhibitors
CN105399686B (en) * 2014-09-16 2018-05-22 深圳微芯生物科技有限责任公司 Pyrimidine derivatives, its preparation method and its application
CN107793417B (en) * 2016-09-05 2020-06-09 复旦大学 Pyrrolo [2,3-d ] pyrimidines and salts thereof, preparation method and medicinal application
WO2018067704A1 (en) * 2016-10-04 2018-04-12 Enanta Pharmaceuticals, Inc. Isoxazole analogs as fxr agonists and methods of use thereof
JP6986086B2 (en) * 2017-01-17 2021-12-22 アストラゼネカ・アクチエボラーグAstrazeneca Aktiebolag JAK1 Selective Inhibitor
CN108794458A (en) * 2018-07-31 2018-11-13 湖北欣瑞康医药科技有限公司 A kind of preparation method of aryl substituted pyrimidine amine acyl derivative
CN110305140B (en) 2019-07-30 2020-08-04 上海勋和医药科技有限公司 Dihydropyrrolopyrimidines selective JAK2 inhibitors
CN112142675B (en) * 2020-10-09 2021-11-30 嘉兴特科罗生物科技有限公司 Small molecule compound as JAK kinase inhibitor and application thereof
CN112375042A (en) * 2020-10-27 2021-02-19 安徽医科大学 Trimethoxy styryl six-membered ring and pyrazolopyrimidine compound, preparation and application thereof
CN113735859A (en) * 2021-08-12 2021-12-03 安徽医科大学 Kinase inhibitor

Also Published As

Publication number Publication date
CN101421250A (en) 2009-04-29

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