WO2011093389A1 - Contenant de stockage de médicament - Google Patents

Contenant de stockage de médicament Download PDF

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Publication number
WO2011093389A1
WO2011093389A1 PCT/JP2011/051630 JP2011051630W WO2011093389A1 WO 2011093389 A1 WO2011093389 A1 WO 2011093389A1 JP 2011051630 W JP2011051630 W JP 2011051630W WO 2011093389 A1 WO2011093389 A1 WO 2011093389A1
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WO
WIPO (PCT)
Prior art keywords
medicine
container
container body
wall
mouth
Prior art date
Application number
PCT/JP2011/051630
Other languages
English (en)
Japanese (ja)
Inventor
伸吾 小山
真司 八巻
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Publication of WO2011093389A1 publication Critical patent/WO2011093389A1/fr

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/02Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/0292Foldable bottles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/05Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
    • A61J1/10Bag-type containers

Definitions

  • the present invention relates to a medicine container.
  • the medicine storage bag placement portion (stage) of the freeze-drying apparatus It is placed on the top in a collapsed state. In this state, the medicine storage bag placement unit is cooled together with the medicine storage bag. Thereby, the liquid composition in the medicine storage bag is freeze-dried, and a powder medicine is generated in the medicine storage bag.
  • An object of the present invention is to provide a medicine container that is suitable for upright and can efficiently produce medicine in the upright state.
  • the present invention provides: A container body having a mouth through which liquid can enter and exit on the distal end side and made of a flexible material, and stored in the container body and dissolved by the liquid flowing in through the mouth.
  • a medicine container comprising a medicine
  • the container body defines a storage space for storing the medicine, and has a pair of wall portions facing each other, One wall portion of the pair of wall portions is formed in at least a part of the wall portion, and is deformed when the liquid is filled in the storage space to increase a volume of the storage space.
  • Have The other wall portion of the pair of wall portions is a medicine storage container characterized in that an average thickness thereof is larger than an average thickness of the deformable portion.
  • the average thickness of the other wall portion is 1.4 to 20 times the average thickness of the deformed portion.
  • a gap is formed between the one wall portion and the other wall portion in an initial state where the liquid is not yet filled in the container body. Is preferred.
  • the mouth portion has a cylindrical shape, When the mouth portion is viewed from the distal end side, a part of the outer peripheral surface of the base end portion of the mouth portion and the surface of the other wall portion are on the same straight line, or the base end portion of the mouth portion It is preferable that a part of the inner peripheral surface and the back surface of the other wall portion are on the same straight line.
  • the container body is manufactured by blow molding.
  • the medicine container of the present invention it is preferable that the medicine is dried by freeze-drying.
  • the deforming portion is formed in the vicinity of the central portion of the one wall portion.
  • a valve body made of an elastic material and having an openable / closable opening / closing portion is attached to the mouth portion.
  • FIG. 1 is a perspective view (a diagram showing an initial state) showing a medicine container of the present invention.
  • FIG. 2 is a cross-sectional view taken along line AA in FIG. 3 is a cross-sectional view taken along line BB in FIG.
  • FIG. 4 is a cross-sectional view of the medicine container shown in FIG.
  • FIG. 5 is a cross-sectional view taken along the line CC in FIG.
  • FIG. 1 is a perspective view showing a medicine container of the present invention
  • FIG. 2 is a cross-sectional view taken along line AA in FIG. 1
  • FIG. 3 is a cross-sectional view taken along line BB in FIG. 1
  • FIG. 5 is a cross-sectional view taken along the line CC in FIG. 2.
  • the upper side in FIGS. 1 and 2 is referred to as “tip”, “up” or “upper”, and the lower side is referred to as “base”, “lower” or “lower”.
  • the drug container 1 is composed of a hollow container body 2 and a powdery medicine Q stored in the container body 2.
  • the drug container 1 shown in FIG. The medicine Q is stored in the container body 2 in advance in the initial state (unused state) shown in FIG.
  • This medicine Q is dissolved by, for example, a solution R filled from a syringe (not shown) through the mouth portion 7 of the container body 2.
  • the drug Q dissolved in the solution R is referred to as “medical solution P”.
  • the state shown in FIG. 4 in which the container body 2 is filled with the solution R is referred to as a “solution-filled state”.
  • the container body 2 is composed of a body part 3 having a storage space 31 for storing the medicine Q, and a mouth part 7 provided at the front end part of the body part 3.
  • the “initial state” is referred to unless otherwise specified.
  • the volume of the storage space 31 in the initial state is not particularly limited, but is preferably 1 to 50 mL, for example, and more preferably 3 to 30 mL.
  • the body portion 3 includes a first wall portion 32a and a second wall portion (the other wall portion) 32b facing each other, and outer peripheries of the first wall portion 32a and the second wall portion 32b. And a frame portion 33 provided on the side.
  • a storage space 31 is defined by the first wall portion 32 a, the second wall portion 32 b, and the frame portion 33.
  • the first wall 32a is recessed near the center.
  • This recessed portion (hereinafter referred to as “deformation portion 35”) is a portion that is deformed when the storage space 31 is filled with the solution R and increases the volume of the storage space 31.
  • the recessed deformed portion 35 has a top portion 322 located at the bottom thereof and an inclined portion 323 formed on the outer peripheral side of the top portion 322.
  • the inclined portion 323 is a portion formed to be inclined from the frame portion 33 side toward the top portion 322.
  • the thickness (thickness) is gradually reduced to satisfy t a1 ⁇ t a2 ⁇ t a3 ⁇ t a4 (see FIG. 2) and t b1 ⁇ t b2 ⁇ t b3 ⁇ t b4 (see FIG. 3).
  • the thickness t a4 (t b4 ) of the second wall portion 32 b is 1.4 to 20 times the thickness t a1 (t b1 ) of the deformed portion 35, particularly the top portion 322.
  • it is 2.0 to 10 times.
  • the container body 2 having such a thickness relationship has mechanical strength maintained up to the frame portion 33 having a thickness of t a3 (t b3 ). Further, the container body 2 has a structure in which when the solution R is filled, the container body 2 starts to be deformed from an intermediate portion 324 between the frame portion 33 and the inclined portion 323 (a portion of the thickness t a2 (t b2 )).
  • the solution R filled through the mouth 7 mainly passes the top portion 322 upward in the drawing. Push up.
  • the intermediate portion 324 is a portion that is easily deformed as described above, the deformable portion 35 is easily protruded from the recessed state shown in FIG. Will increase in volume.
  • the storage space 31 with the increased volume is filled with a sufficient amount of the drug Q, that is, the drug Q that can be dissolved without excess or deficiency, so that the drug solution P can be generated.
  • the second wall portion 32b is the thickest portion, that is, a portion where the average thickness is thicker than the average thickness of the deformable portion 35.
  • the container body 2 stands upright from the second wall portion 32b having the largest thickness so that the mouth portion 7 is positioned upward in the vertical direction, the container body 2 is maintained in the upright state (see FIG. 2). Therefore, when the container body 2 is regarded as a human body, the container body 2 functions like a “spine” and has a shape suitable for upright. Thereby, when the medicine storage container 1 in an upright state is placed on, for example, the stage 101 of the freeze-drying apparatus 10 described later, the medicine storage container 1 is stably placed on the stage 101 in the upright state. Placed.
  • the thickness of the second wall portion 32b is set to such an extent that the second wall portion 32b is not substantially deformed when the solution is filled (see FIG. 4). Thereby, the second wall 32b is prevented from being unintentionally deformed, for example, from the initial state to the solution filling state, so that the upright state of the container body 2 can be reliably maintained.
  • the gap 311 is formed. That is, in the initial state, the top portion 322 of the first wall portion 32a and the second wall portion 32b are provided so that the inner surfaces (rear surfaces) 321 face each other in a non-contact manner.
  • the solution R that has flowed in through the mouth portion 7 can pass through the gap 311, and thus quickly reaches the entire storage space 31. Thereby, the solution R can be easily and reliably filled, and thus the drug Q is dissolved in the solution R.
  • the gap distance d1 in the initial state is not particularly limited, but is preferably 0.5 to 25 mm, for example, and more preferably 1 to 15 mm.
  • the gap distance d1 is within such a numerical range, the container body 2 can be stably manufactured when the container body 2 is manufactured by blow molding.
  • a band-shaped frame portion 33 is provided on the outer peripheral side of the first wall portion 32a and the second wall portion 32b so as to surround these wall portions.
  • the shape of the medicine container 1 in the initial state is maintained by the frame portion 33, and thus the medicine container 1 is easily expanded when the solution R is filled. Further, the shape of the medicine container 1 in the state of being filled with the dissolution liquid is also maintained, and therefore, for example, the medicine container 1 can be easily grasped.
  • the frame portion 33 is formed with a flat bottom portion 336 at the base end portion thereof.
  • the container body 2 (including the body portion 3 and the cylindrical portion 72 of the mouth portion 7) as described above is made of a flexible material, that is, a soft resin material.
  • the soft resin material is not particularly limited.
  • EVA ethylene-vinyl acetate copolymer
  • PET polyethylene terephthalate
  • PBT polybutylene terephthalate
  • examples thereof include various thermoplastic elastomers such as polyester, soft polyvinyl chloride, polyvinylidene chloride, silicone, polyurethane, and polyamide elastomer, or any combination thereof (blend resin, polymer alloy, laminate, etc.).
  • drum 3 may be comprised by the single layer, and may be comprised by the laminated body by which the several
  • the container body 2 made of such a soft resin material is manufactured by blow molding.
  • the inner surface of the container body 2 can be made smooth.
  • the drug Q may be sandwiched near the fused portion and may not be in contact with the solution R. Such a problem can be prevented in the case of the container body 2 that has been made.
  • the mouth portion 7 through which the solution R flows and the solution P flows out is disposed on the distal end side of the drug container 1.
  • a valve body 5 having a self-occlusion property made of an elastic material is attached to the mouth portion 7.
  • a rubber stopper or the like that can be punctured with a needle may be used.
  • the mouth portion 7 includes a cylindrical portion 72 having a cylindrical shape protruding from the frame portion 33 and a lid portion 73 attached to the cylindrical portion 72.
  • the cylindrical portion 72 has a part of the outer peripheral surface 726 and the surface of the second wall portion 32 b in a cross-sectional view (the same applies when the mouth portion 7 is viewed from the distal end side).
  • 326 is on the same straight line, and a part of the inner peripheral surface 727 of the cylindrical part 72 and the inner surface 321 of the second wall part 32b are preferably on the same straight line. Thereby, the thickness of the 2nd wall part 32b is fully securable.
  • the tubular portion 72 has a valve body installation portion 721 formed therein.
  • the valve body setting portion 721 is divided into a second lumen portion 723 and a third lumen portion 724 that is located on the proximal end side and is smaller in diameter than the inner diameter of the second lumen portion 723. be able to.
  • bore part 724 is a little larger than the largest outer diameter of the trunk
  • an inner protrusion 725 made of a tubular body is provided at the center of the bottom surface 722 of the cylindrical portion 72.
  • the internal protrusion 725 supports the inside of the valve body 5 and causes the valve body 5 to buckle. Can be prevented. Further, when the solution R passes through the mouth portion 7, it is possible to prevent the solution R from staying.
  • the lid portion 73 has a lumen portion that accommodates the valve body 5 therein, and is connected to the cylindrical portion 72.
  • the lid portion 73 is made of, for example, a hard resin material.
  • a first lumen portion 731 into which a later-described head portion 50 of the valve body 5 can be inserted, and the first lumen portion 731 are communicated with and expanded from the first lumen portion 731.
  • a diameter fitting portion 733 is formed.
  • the first lumen portion 731 is formed so that its shape corresponds to the outer shape of the head 50 of the valve body 5.
  • the fitting part 733 is a part that fits to the outer peripheral part of the cylindrical part 72.
  • the lid part 73 and the cylindrical part 72 are connected in a liquid-tight manner, and accordingly, it is possible to prevent the dissolution liquid R inside the mouth part 7 from leaking between the lid part 73 and the cylindrical part 72. it can.
  • the first lumen portion 731 and the second lumen portion 723 communicate with each other, and the first lumen portion 731 and the second lumen portion are connected.
  • the valve body 5 can be installed in the space formed by the 723 and the third lumen portion 724.
  • a male screw portion 738 is formed on the outer periphery of the lid portion 73.
  • the male screw portion 738 is a portion that is screwed with the syringe when the syringe is connected to the mouth portion 7.
  • the inner lumen functions as a flow path through which the solution R can pass.
  • a valve body 5 is installed in the mouth portion 7.
  • the valve body 5 include various rubber materials such as isoprene rubber, and various thermoplastic elastomers such as polyolefin, and one or more of these can be used in combination.
  • an elastic material moderate elasticity can be obtained on the tip surface 511 of the valve body 5.
  • the valve body 5 includes a tubular body portion 55 and a head portion 50 provided integrally with one end portion of the body portion 55.
  • the head 50 has a bottomed cylindrical shape, and has a lumen portion 515 through which the solution R and the drug solution P can pass, and a slit (open / close) that reaches the lumen portion 515 from the flat distal end surface 511.
  • Part) 512 The slit 512 has a substantially single character shape. Since the shape of the slit 512 is so simple, the front end surface 511 is deformed when the vicinity of the slit 512 of the front end surface 511 is pressed, and thus the slit 512 is reliably opened. Further, when the pressing is released, the front end surface 511 is restored, so that the slit 512 is reliably closed. Thus, the valve body 5 has a self-occlusion property.
  • the mouth portion 7 can be easily and reliably sealed / unsealed.
  • the head portion 50 is inserted into the first lumen portion 731 of the lid portion 73, and the slit 512 is closed.
  • the trunk portion 55 is formed of a cylindrical body having a bellows shape. That is, the body 55 has a bellows shape in which the large-diameter ring portion 552 and the small-diameter ring portion 553 are alternately arranged in the axial direction in the outer shape. Such a body portion 55 functions as a deforming portion that urges the head portion 50 in a direction in which the head portion 50 is inserted into the first lumen portion 731 of the lid portion 73.
  • the medicine Q is accommodated in the container body 2 having the above-described configuration.
  • the drug Q is not particularly limited.
  • an anticancer drug, an immunosuppressive drug, or the like which is dangerous when a medical worker touches it accidentally, or a drug that needs to be dissolved when using antibiotics, hemostatic agents, etc.
  • Drugs that require dilution such as drugs for children, vaccines, heparin, drugs for children, etc.
  • the solution R for dissolving the drug Q is filled in the drug container 1 using a syringe as described above, and can be, for example, physiological saline.
  • Drug Q is obtained by drying a liquid composition containing the drug Q by freeze-drying.
  • the drug Q is produced in the container body 2 using the freeze-drying apparatus 10 as follows.
  • the freeze-drying apparatus 10 has a plate-like stage 101 (see FIG. 2).
  • the freeze-drying apparatus 10 is configured so that the stage 101 can be cooled.
  • the container body 2 is placed on the stage 101 in an upright state, and the liquid composition is filled in the storage space 31 in this state. Since the container main body 2 is suitable for upright as described above, the upright state is maintained, and therefore, the container body 2 is prevented from falling unintentionally. Then, the stage 101 is cooled together with the container body 2 on the stage 101. Since the container body 2 is in surface contact with the stage 101 via the flat bottom portion 336, the liquid composition in the storage space 31 is lyophilized to obtain the medicine Q.
  • the liquid Q in the storage space 31 can be freeze-dried in an upright state to efficiently manufacture the medicine Q.
  • the container body 2 is placed in an upright state on the stage 101.
  • the number of placement of the container main body 2 placed on the stage 101 is larger than when the container main body 2 is placed in a tilted state.
  • the medicine container 1 in the initial state shown in FIG. 1 and a syringe filled with the solution R are prepared.
  • This syringe is filled with a solution R having a sufficient amount to dissolve the drug Q in the drug container 1.
  • the syringe pusher is pressed.
  • the solution R in the syringe is injected into the drug container 1 through the mouth portion 7 of the drug container 1, and the drug container 1 is filled with the solution (see FIG. 4).
  • the injected dissolving solution R first flows down the storage space 31 along the frame portion 33 and then enters the gap 311. As a result, the entire storage space 31 is filled with the solution R.
  • the solution R since the solution R tries to spread the top portion 322 of the first wall portion 32a outward, the intermediate portion 324 starts to deform, and the volume of the storage space 31 increases. Increase.
  • the solution R can be easily and surely filled in the medicine container 1.
  • the filling amount of the solution R can be set to be equal to or less than the maximum volume of the storage space 31 of the medicine storage container 1.
  • the syringe from which the drug solution P has been aspirated can be used, for example, for drug solution administration to a patient.
  • medical agent storage container is arbitrary structures which can exhibit the same function. Can be substituted. Moreover, arbitrary components may be added.
  • the container body is not limited to those manufactured by blow molding, and may be manufactured by, for example, joining a pair of halves that form the container body.
  • the medicine container may be prefilled with an inert gas such as nitrogen.
  • an inert gas such as nitrogen.
  • the medicine to be stored is in a powder form in each of the above embodiments, but is not limited thereto, and may be in a tablet form, a gel form, or a liquid form, for example.
  • valve body is attached to the mouth portion of the medicine storage container in each of the embodiments described above, the present invention is not limited to this, and the valve body may be omitted.
  • the drug storage container of the present invention has a mouth part through which liquid can enter and exit on the tip side, a container body made of a flexible material, and housed in the container body, via the mouth part
  • a medicine storage container including a medicine dissolved by the flowed-in liquid, wherein the container main body defines a storage space for storing the medicine, and has a pair of wall portions facing each other, One wall portion of the wall portions is formed in at least a part thereof, and has a deformation portion that deforms when the storage space is filled with the liquid and increases the volume of the storage space, The other wall portion of the pair of wall portions has an average thickness that is greater than an average thickness of the deformable portion.
  • the medicine storage container When the container body stands upright so that the mouth portion is positioned vertically upward, the upright state is reliably maintained by the thicker wall portion of the pair of wall portions.
  • the medicine storage container When the medicine storage container is placed on a flat plate such as a table in the upright state, the medicine storage container is stably placed on the flat plate.
  • the medicine container is suitable for upright.
  • the freeze-drying apparatus When the medicine stored in the container body is obtained by freeze-drying a liquid composition containing the medicine, the freeze-drying apparatus has the above-described flat plate stage on the stage.
  • the medicine container filled with the liquid composition is placed in an upright state, and the medicine container is cooled together with the stage in this state. Thereby, the said liquid composition is cooled reliably and, therefore, a chemical
  • the medicine container can be efficiently produced by cooling the liquid composition in the container body in an upright state. Therefore, the medicine storage container of the present invention has industrial applicability.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ceramic Engineering (AREA)
  • Mechanical Engineering (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

L'invention porte sur un contenant de stockage de médicament comprenant : un corps de contenant constitué d'un matériau souple et ayant, sur le côté d'extrémité avant de celui-ci, une section d'embouchure par l'intermédiaire de laquelle un liquide peut entrer et sortir du corps de contenant ; et un médicament contenu à l'intérieur du corps de contenant et dissous par le liquide s'écoulant dans le corps de contenant à travers la section d'embouchure. Dans le contenant de stockage de médicament, le corps de contenant à une paire de sections de paroi définissant un espace de stockage pour stocker le médicament et tournées l'une vers l'autre. L'une des paires de sections de paroi a une section de déformation formée au niveau d'au moins une partie de ladite section de paroi et qui, lorsque le liquide est introduit dans l'espace de stockage, se déforme pour augmenter le volume de l'espace de stockage. L'épaisseur moyenne de l'autre section de paroi est supérieure à l'épaisseur moyenne de la section de déformation.
PCT/JP2011/051630 2010-01-28 2011-01-27 Contenant de stockage de médicament WO2011093389A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010-017472 2010-01-28
JP2010017472 2010-01-28

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WO2011093389A1 true WO2011093389A1 (fr) 2011-08-04

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Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013035543A1 (fr) * 2011-09-07 2013-03-14 テルモ株式会社 Contenant médical et procédé de fabrication d'un contenant médical
WO2013047030A1 (fr) * 2011-09-27 2013-04-04 テルモ株式会社 Récipient médical
WO2013047029A1 (fr) * 2011-09-27 2013-04-04 テルモ株式会社 Récipient médical
US20160207750A1 (en) * 2013-08-29 2016-07-21 Kronges Ag Method for producing containers filled with a liquid
CN112689606A (zh) * 2020-12-17 2021-04-20 深圳市宏讯实业有限公司 储料供料装置
EP3791121A4 (fr) * 2018-05-07 2022-01-05 Merck Sharp & Dohme Corp. Sac de lyophilisation

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11130033A (ja) * 1997-10-31 1999-05-18 Yoshino Kogyosho Co Ltd 合成樹脂製片壁薄肉容器
JP2002078774A (ja) * 2000-09-07 2002-03-19 Otsuka Pharmaceut Factory Inc 薬剤容器連結体
JP2002104355A (ja) * 2000-09-29 2002-04-10 Yoshino Kogyosho Co Ltd 合成樹脂製壜体
JP2010179063A (ja) * 2009-02-09 2010-08-19 Terumo Corp 薬剤収納容器

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11130033A (ja) * 1997-10-31 1999-05-18 Yoshino Kogyosho Co Ltd 合成樹脂製片壁薄肉容器
JP2002078774A (ja) * 2000-09-07 2002-03-19 Otsuka Pharmaceut Factory Inc 薬剤容器連結体
JP2002104355A (ja) * 2000-09-29 2002-04-10 Yoshino Kogyosho Co Ltd 合成樹脂製壜体
JP2010179063A (ja) * 2009-02-09 2010-08-19 Terumo Corp 薬剤収納容器

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013035543A1 (fr) * 2011-09-07 2013-03-14 テルモ株式会社 Contenant médical et procédé de fabrication d'un contenant médical
CN103796624A (zh) * 2011-09-07 2014-05-14 泰尔茂株式会社 医疗用容器和医疗用容器的制造方法
JPWO2013035543A1 (ja) * 2011-09-07 2015-03-23 テルモ株式会社 医療用容器および医療用容器の製造方法
CN103796624B (zh) * 2011-09-07 2016-05-18 泰尔茂株式会社 医疗用容器和医疗用容器的制造方法
US9700487B2 (en) 2011-09-07 2017-07-11 Terumo Kabushiki Kaisha Medical container and method of manufacturing the same
WO2013047030A1 (fr) * 2011-09-27 2013-04-04 テルモ株式会社 Récipient médical
WO2013047029A1 (fr) * 2011-09-27 2013-04-04 テルモ株式会社 Récipient médical
JPWO2013047029A1 (ja) * 2011-09-27 2015-03-26 テルモ株式会社 医療用容器
US9668938B2 (en) 2011-09-27 2017-06-06 Terumo Kabushiki Kaisha Medical container
US20160207750A1 (en) * 2013-08-29 2016-07-21 Kronges Ag Method for producing containers filled with a liquid
EP3791121A4 (fr) * 2018-05-07 2022-01-05 Merck Sharp & Dohme Corp. Sac de lyophilisation
CN112689606A (zh) * 2020-12-17 2021-04-20 深圳市宏讯实业有限公司 储料供料装置

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