UA80601C2 - The pyrimidin derivatives for the prevention of hiv infection - Google Patents

The pyrimidin derivatives for the prevention of hiv infection Download PDF

Info

Publication number: UA80601C2
Authority: UA; Ukraine
Prior art keywords: alkyl; group; substituted; cyano group; amino
Prior art date: 2003-02-07

Application number

UAA200508362A

Other languages

English (en)

Ukrainian (uk)

Inventor

Jan Heeres

Paulus Johannes Levi

Jonge Marc De

Lucien Maria Henricus Coimans

Frederick France Desire Deiert

Hendrick Maarten Vinckers

Jerome Emil George Guillemont

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-02-07

Filing date

2004-04-02

Publication date

2007-10-10

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32842658&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA80601(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-04-02 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2007-10-10 Publication of UA80601C2 publication Critical patent/UA80601C2/uk

Links

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Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/48—Two nitrogen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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UAA200508362A 2003-02-07 2004-04-02 The pyrimidin derivatives for the prevention of hiv infection UA80601C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP0301291		2003-02-07
PCT/EP2004/001011 WO2004069812A1 (en)	2003-02-07	2004-02-04	Pyrimidine derivatives for the prevention of hiv infection

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UA80601C2 true UA80601C2 (en)	2007-10-10

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UAA200508362A UA80601C2 (en)	2003-02-07	2004-04-02	The pyrimidin derivatives for the prevention of hiv infection

Country Status (22)

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US (2)	US20070021449A1 (ko)
EP (1)	EP1597237B1 (ko)
JP (2)	JP5602333B2 (ko)
KR (2)	KR20110132482A (ko)
CN (2)	CN102151270A (ko)
AP (1)	AP2065A (ko)
AU (1)	AU2004210081B2 (ko)
BR (1)	BRPI0407329A (ko)
CA (1)	CA2513527C (ko)
CL (1)	CL2004000192A1 (ko)
EA (1)	EA011164B1 (ko)
ES (1)	ES2598404T3 (ko)
HR (1)	HRP20050688B1 (ko)
IL (1)	IL170114A (ko)
MX (1)	MXPA05008364A (ko)
MY (1)	MY176490A (ko)
NO (1)	NO334178B1 (ko)
NZ (1)	NZ541902A (ko)
PL (1)	PL227577B1 (ko)
UA (1)	UA80601C2 (ko)
WO (1)	WO2004069812A1 (ko)
ZA (1)	ZA200506253B (ko)

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- 2004-02-04 US US10/544,735 patent/US20070021449A1/en not_active Abandoned
- 2004-02-04 NZ NZ541902A patent/NZ541902A/en not_active IP Right Cessation
- 2004-02-04 WO PCT/EP2004/001011 patent/WO2004069812A1/en active Application Filing
- 2004-02-04 EA EA200501265A patent/EA011164B1/ru unknown
- 2004-02-04 JP JP2006501729A patent/JP5602333B2/ja not_active Expired - Lifetime
- 2004-02-04 BR BR0407329-0A patent/BRPI0407329A/pt not_active Application Discontinuation
- 2004-02-04 AU AU2004210081A patent/AU2004210081B2/en not_active Expired
- 2004-02-04 AP AP2005003366A patent/AP2065A/en active
- 2004-02-05 MY MYPI20040342A patent/MY176490A/en unknown
- 2004-04-02 UA UAA200508362A patent/UA80601C2/uk unknown
2005
- 2005-08-01 HR HRP20050688AA patent/HRP20050688B1/hr not_active IP Right Cessation
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- 2005-08-04 IL IL170114A patent/IL170114A/en active IP Right Grant
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2009
- 2009-09-25 US US12/567,051 patent/US8828982B2/en active Active
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Also Published As

Publication number	Publication date
ES2598404T3 (es)	2017-01-27
JP2014144988A (ja)	2014-08-14
KR20050102094A (ko)	2005-10-25
US8828982B2 (en)	2014-09-09
CN1747937A (zh)	2006-03-15
AP2005003366A0 (en)	2005-09-30
EA200501265A1 (ru)	2006-02-24
NZ541902A (en)	2008-12-24
KR20110132482A (ko)	2011-12-07
KR101185048B1 (ko)	2012-09-21
WO2004069812A1 (en)	2004-08-19
CA2513527A1 (en)	2004-08-19
PL227577B1 (pl)	2017-12-29
MXPA05008364A (es)	2005-11-04
EP1597237B1 (en)	2016-07-27
HRP20050688B1 (hr)	2017-03-24
CA2513527C (en)	2012-08-14
IL170114A (en)	2011-09-27
NO20054143D0 (no)	2005-09-06
MY176490A (en)	2020-08-12
AU2004210081B2 (en)	2009-11-26
EA011164B1 (ru)	2009-02-27
NO334178B1 (no)	2014-01-06
US20100034810A1 (en)	2010-02-11
EP1597237A1 (en)	2005-11-23
AU2004210081A1 (en)	2004-08-19
US20070021449A1 (en)	2007-01-25
PL378144A1 (pl)	2006-03-06
JP2006516591A (ja)	2006-07-06
CL2004000192A1 (es)	2005-03-18
HRP20050688A2 (en)	2006-08-31
AP2065A (en)	2009-11-26
JP5602333B2 (ja)	2014-10-08
ZA200506253B (en)	2008-05-28
NO20054143L (no)	2005-09-06
BRPI0407329A (pt)	2006-01-10
JP5799133B2 (ja)	2015-10-21
CN102151270A (zh)	2011-08-17

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