SG10201510696RA - Heteroaryl compounds and uses thereof - Google Patents

Heteroaryl compounds and uses thereof

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Publication number
SG10201510696RA
SG10201510696RA SG10201510696RA SG10201510696RA SG10201510696RA SG 10201510696R A SG10201510696R A SG 10201510696RA SG 10201510696R A SG10201510696R A SG 10201510696RA SG 10201510696R A SG10201510696R A SG 10201510696RA SG 10201510696R A SG10201510696R A SG 10201510696RA
Authority
SG
Singapore
Prior art keywords
heteroaryl compounds
heteroaryl
compounds
Prior art date
Application number
SG10201510696RA
Inventor
Lixin Qiao
Juswinder Singh
Arthur F Kluge
William Frederick Westlin
Russell C Petter
Richland Wayne Tester
Deqiang Niu
Hormoz Mazdiyasni
Original Assignee
Celgene Avilomics Res Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Avilomics Res Inc filed Critical Celgene Avilomics Res Inc
Publication of SG10201510696RA publication Critical patent/SG10201510696RA/en

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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/538—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D487/18—Bridged systems
SG10201510696RA 2008-06-27 2009-06-26 Heteroaryl compounds and uses thereof SG10201510696RA (en)

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US7645008P 2008-06-27 2008-06-27
US14838809P 2009-01-29 2009-01-29
US17087409P 2009-04-20 2009-04-20

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SG10201510696RA true SG10201510696RA (en) 2016-01-28

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US (6) US8450335B2 (en)
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JP (4) JP2011526299A (en)
KR (3) KR101955914B1 (en)
CN (2) CN102083800A (en)
AU (1) AU2009262068C1 (en)
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CA (3) CA3031835C (en)
DK (1) DK2361248T3 (en)
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IL (3) IL209969A (en)
MX (3) MX360970B (en)
NZ (3) NZ589843A (en)
PH (1) PH12015501484A1 (en)
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