TNSN07154A1 - Purine derivatives for use as adenosin a-2a receptor agonists - Google Patents

Purine derivatives for use as adenosin a-2a receptor agonists

Info

Publication number
TNSN07154A1
TNSN07154A1 TNP2007000154A TNSN07154A TNSN07154A1 TN SN07154 A1 TNSN07154 A1 TN SN07154A1 TN P2007000154 A TNP2007000154 A TN P2007000154A TN SN07154 A TNSN07154 A TN SN07154A TN SN07154 A1 TNSN07154 A1 TN SN07154A1
Authority
TN
Tunisia
Prior art keywords
adenosin
receptor agonists
purine derivatives
compounds
receptor
Prior art date
Application number
TNP2007000154A
Other languages
English (en)
Inventor
Robin Alec Fairhurst
Roger John Taylor
Paul Singh
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0423551A external-priority patent/GB0423551D0/en
Priority claimed from GB0514619A external-priority patent/GB0514619D0/en
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of TNSN07154A1 publication Critical patent/TNSN07154A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
    • C07D473/16—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
TNP2007000154A 2004-10-22 2007-04-20 Purine derivatives for use as adenosin a-2a receptor agonists TNSN07154A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0423551A GB0423551D0 (en) 2004-10-22 2004-10-22 Organic compounds
GB0514619A GB0514619D0 (en) 2005-07-15 2005-07-15 Organic compounds
PCT/EP2005/011344 WO2006045552A1 (fr) 2004-10-22 2005-10-21 Derives de purine utilises comme agonistes des recepteurs a-2a de l'adenosine

Publications (1)

Publication Number Publication Date
TNSN07154A1 true TNSN07154A1 (en) 2008-11-21

Family

ID=35589070

Family Applications (1)

Application Number Title Priority Date Filing Date
TNP2007000154A TNSN07154A1 (en) 2004-10-22 2007-04-20 Purine derivatives for use as adenosin a-2a receptor agonists

Country Status (21)

Country Link
US (1) US8163754B2 (fr)
EP (2) EP2292619A1 (fr)
JP (1) JP4904279B2 (fr)
KR (1) KR20070073798A (fr)
AR (1) AR051642A1 (fr)
AU (2) AU2005298878B2 (fr)
BR (1) BRPI0517455A (fr)
CA (1) CA2582434A1 (fr)
EC (1) ECSP077404A (fr)
ES (1) ES2394453T3 (fr)
GT (1) GT200500281A (fr)
IL (1) IL182528A0 (fr)
MA (1) MA28931B1 (fr)
MX (1) MX2007004735A (fr)
NO (1) NO20072122L (fr)
NZ (1) NZ554546A (fr)
PE (2) PE20100266A1 (fr)
RU (1) RU2403253C2 (fr)
TN (1) TNSN07154A1 (fr)
TW (1) TW200630366A (fr)
WO (1) WO2006045552A1 (fr)

Families Citing this family (17)

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GT200500281A (es) 2004-10-22 2006-04-24 Novartis Ag Compuestos organicos.
GB0500785D0 (en) 2005-01-14 2005-02-23 Novartis Ag Organic compounds
GB0607944D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
PT2013211E (pt) 2006-04-21 2012-06-21 Novartis Ag Derivados de purina para utilização como agonistas de receptores a2a de adenosina
GB0607953D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607948D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607950D0 (en) 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607945D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
GB0607954D0 (en) * 2006-04-21 2006-05-31 Novartis Ag Organic compounds
EP1889846A1 (fr) 2006-07-13 2008-02-20 Novartis AG Dérivés de purine comme agonistes du recepteur A2a
EP1903044A1 (fr) * 2006-09-14 2008-03-26 Novartis AG Derivés de l'adénosine en tant qu' agonistes du récepteur A2A
JP2010508835A (ja) * 2006-11-10 2010-03-25 ノバルティス アーゲー シクロペンテンジオールモノアセテート誘導体
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US20090181934A1 (en) * 2007-10-17 2009-07-16 Novartis Ag Organic Compounds
JP2011500631A (ja) * 2007-10-17 2011-01-06 ノバルティス アーゲー アデノシンａ１受容体リガンドとしてのプリン誘導体
CA2766073A1 (fr) 2009-06-30 2011-01-06 Forest Laboratories Holdings Limited Composes alcoxy-carbonyl-amino-alcynyle-adenosine et derives de ceux-ci en tant qu'agonistes de a2a r
EP3039126B1 (fr) 2013-08-26 2019-10-09 The J. David Gladstone Institutes, A Testamentary Trust Established under The Will of J. David Gladstone Reprogrammation cellulaire par petites molécules pour générer des cellules neuronales

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