SE9402510D0 - Process for synthesis of substituted 2-(2-pyridinylmethylsulphinyl)-1H-benzimidazoles - Google Patents

Process for synthesis of substituted 2-(2-pyridinylmethylsulphinyl)-1H-benzimidazoles

Info

Publication number
SE9402510D0
SE9402510D0 SE9402510A SE9402510A SE9402510D0 SE 9402510 D0 SE9402510 D0 SE 9402510D0 SE 9402510 A SE9402510 A SE 9402510A SE 9402510 A SE9402510 A SE 9402510A SE 9402510 D0 SE9402510 D0 SE 9402510D0
Authority
SE
Sweden
Prior art keywords
pct
benzimidazoles
date
sec
substituted
Prior art date
Application number
SE9402510A
Other languages
English (en)
Other versions
SE9402510L (sv
SE504459C2 (sv
Inventor
Magnus Larsson
Henrik Soerensen
Urban Stenhede
Unge Sverker Von
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=20394753&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SE9402510(D0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE9402510A priority Critical patent/SE504459C2/sv
Publication of SE9402510D0 publication Critical patent/SE9402510D0/sv
Priority to UA97020638A priority patent/UA47409C2/uk
Priority to EE9700006A priority patent/EE03354B1/xx
Priority to SK48-97A priority patent/SK284059B6/sk
Priority to AT95926068T priority patent/ATE242233T1/de
Priority to PCT/SE1995/000818 priority patent/WO1996002535A1/en
Priority to DE69530987T priority patent/DE69530987T3/de
Priority to ES95926068T priority patent/ES2199998T5/es
Priority to CA002193994A priority patent/CA2193994C/en
Priority to US08/492,087 priority patent/US5948789A/en
Priority to KR1019970700221A priority patent/KR100356252B1/ko
Priority to MX9700358D priority patent/MX9700358A/es
Priority to BR9508292A priority patent/BR9508292A/pt
Priority to PT95926068T priority patent/PT773940E/pt
Priority to DK95926068.8T priority patent/DK0773940T4/da
Priority to AU29948/95A priority patent/AU688074B2/en
Priority to JP50493896A priority patent/JP3795917B2/ja
Priority to RU97102162/04A priority patent/RU2157806C2/ru
Priority to SI9530676T priority patent/SI0773940T2/sl
Priority to EP95926068A priority patent/EP0773940B2/en
Priority to TW084106875A priority patent/TW372971B/zh
Priority to CN95194956A priority patent/CN1070489C/zh
Priority to CZ0006497A priority patent/CZ297987B6/cs
Priority to NZ289959A priority patent/NZ289959A/en
Priority to HU9700108A priority patent/HU226361B1/hu
Priority to PL95318165A priority patent/PL186342B1/pl
Priority to IL11447795A priority patent/IL114477A/en
Priority to MA23950A priority patent/MA23611A1/fr
Priority to ZA955724A priority patent/ZA955724B/xx
Priority to DZ950088A priority patent/DZ1911A1/fr
Priority to EG57195A priority patent/EG24534A/xx
Priority to HR950401A priority patent/HRP950401B1/xx
Priority to TNTNSN95081A priority patent/TNSN95081A1/fr
Priority to YU47695A priority patent/YU49475B/sh
Priority to TR95/00861A priority patent/TR199500861A2/xx
Priority to MYPI95001998A priority patent/MY113180A/en
Priority to SA95160294A priority patent/SA95160294B1/ar
Publication of SE9402510L publication Critical patent/SE9402510L/sv
Priority to ARP960103398A priority patent/AR003443A1/es
Priority to IS4406A priority patent/IS1772B/is
Priority to FI970102A priority patent/FI117672B/sv
Priority to FI970102D priority patent/FI117830B/sv
Priority to NO19970153A priority patent/NO312101B1/no
Publication of SE504459C2 publication Critical patent/SE504459C2/sv
Priority to HK98109230A priority patent/HK1008331A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/28—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SE9402510A 1994-07-15 1994-07-15 Förfarande för framställning av substituerade sulfoxider SE504459C2 (sv)

Priority Applications (43)

Application Number Priority Date Filing Date Title
SE9402510A SE504459C2 (sv) 1994-07-15 1994-07-15 Förfarande för framställning av substituerade sulfoxider
SI9530676T SI0773940T2 (sl) 1994-07-15 1995-07-03 Postopek za sintezo substituiranih sulfoksidov
EP95926068A EP0773940B2 (en) 1994-07-15 1995-07-03 Process for synthesis of substituted sulphoxides
US08/492,087 US5948789A (en) 1994-07-15 1995-07-03 Process for synthesis of substituted sulphoxides
KR1019970700221A KR100356252B1 (ko) 1994-07-15 1995-07-03 치환술폭시드의합성방법
SK48-97A SK284059B6 (sk) 1994-07-15 1995-07-03 Spôsob prípravy substituovaných sulfoxidov
AT95926068T ATE242233T1 (de) 1994-07-15 1995-07-03 Verfahren zur herstellung von substituierten sulfoxiden
PCT/SE1995/000818 WO1996002535A1 (en) 1994-07-15 1995-07-03 Process for synthesis of substituted sulphoxides
DE69530987T DE69530987T3 (de) 1994-07-15 1995-07-03 Verfahren zur herstellung von substituierten sulfoxiden
ES95926068T ES2199998T5 (es) 1994-07-15 1995-07-03 Procedimiento para la síntesis de sulfóxidos sustituidos.
CA002193994A CA2193994C (en) 1994-07-15 1995-07-03 Process for synthesis of substituted sulphoxides
UA97020638A UA47409C2 (uk) 1994-07-15 1995-07-03 Спосіб синтезу заміщених сульфоксидів (варіанти) та сульфоксид
EE9700006A EE03354B1 (et) 1994-07-15 1995-07-03 Asendatud sulfoksiidide sünteesi protsess
MX9700358D MX9700358A (es) 1994-07-15 1995-07-03 Proceso par a la sintesis de sulfoxidos substituidos.
BR9508292A BR9508292A (pt) 1994-07-15 1995-07-03 Processos para a sintese enãncio-seletiva de um composto,(-)-5-metóxi-2[[(4-metóxi-3,5-dimetil-2-piridinil) metil]sulfinil]-1h-benzimidazol,(+)-5-fluoro-2-(((4-ciclopropilmetóxi-2-piridinil) metil) sulfinil)-1h-benzimidazol,(-)-5-fluoro-2-(((4-ciclopropilmetóxi-2-piridinil) metil) sulfinil)-1h-benzimidazol,(-)-5-fluoro-2-(((4-ciclopropilmetóxi-2-piridinil) metil) sulfinil)-1h-benzimidazol,(-)-5-carbometóxi-6-metil-2-[[(3,4-dimetóxi-2-piridinil) metil] sulfinil]-1h-benzimidazol,(+)-5-carbometóxi-6-metil-2-[[(3,4-dimetóxi-2-piridinil) metil] sulfinil]-1h benzimidazol composto e uso dos compostos
PT95926068T PT773940E (pt) 1994-07-15 1995-07-03 Processo de sintese de sulfoxidos substituidos
DK95926068.8T DK0773940T4 (da) 1994-07-15 1995-07-03 Fremgangsmåde til syntese af substituerede sulfoxider
AU29948/95A AU688074B2 (en) 1994-07-15 1995-07-03 Process for synthesis of substituted sulphoxides
JP50493896A JP3795917B2 (ja) 1994-07-15 1995-07-03 置換スルホキシドの合成法
RU97102162/04A RU2157806C2 (ru) 1994-07-15 1995-07-03 Способы синтеза замещенных сульфоксидов
TW084106875A TW372971B (en) 1994-07-15 1995-07-04 Process for synthesis of substituted sulphoxides
HU9700108A HU226361B1 (en) 1994-07-15 1995-07-05 Process for synthesis of substituted sulphoxides
CZ0006497A CZ297987B6 (cs) 1994-07-15 1995-07-05 Zpusob prípravy substituovaných sulfoxidu
CN95194956A CN1070489C (zh) 1994-07-15 1995-07-05 取代的亚砜类化合物的合成方法
PL95318165A PL186342B1 (pl) 1994-07-15 1995-07-05 Sposób enancjoselektywnej syntezy związku sulfotlenkowego
NZ289959A NZ289959A (en) 1994-07-15 1995-07-05 Process for enantioselective synthesis of substituted 2-[(2-pyridinyl(or phenyl)methyl)sulphinyl]-1h-[benzimidazole (or thienoimidazole)] (including omeprazole) and other structurally related suphoxides and salts thereof
IL11447795A IL114477A (en) 1994-07-15 1995-07-06 A process for the enantioselective synthesis of converted sulfoxides, individual enantiomers obtained as a result of the process and their use in the preparation of drugs
MA23950A MA23611A1 (fr) 1994-07-15 1995-07-10 Procede pour la synthese de sulfoxydes substitues
ZA955724A ZA955724B (en) 1994-07-15 1995-07-10 Process for synthesis of substituted sulphoxides
DZ950088A DZ1911A1 (fr) 1994-07-15 1995-07-11 Procédé pour la synthèse de sulfoxydes substitues.
EG57195A EG24534A (en) 1994-07-15 1995-07-11 Process for synthesis of substituted sulfoxides
HR950401A HRP950401B1 (en) 1994-07-15 1995-07-12 Process for synthesis of substituted sulphoxides
TNTNSN95081A TNSN95081A1 (fr) 1994-07-15 1995-07-13 Procede pour la synthese de sulfoxydes substitues
MYPI95001998A MY113180A (en) 1994-07-15 1995-07-14 Process for synthesis of substituted sulfoxides
YU47695A YU49475B (sh) 1994-07-15 1995-07-14 Postupak za sintezu supstituisanih sulfoksida
TR95/00861A TR199500861A2 (tr) 1994-07-15 1995-07-14 Ikame edilmis sulfoksidlerin sentezi icin proses.
SA95160294A SA95160294B1 (ar) 1994-07-15 1995-10-07 عملية لتحضير synthesisمركبات سلفوكسيد مستبدلة substituted sulphoxide
ARP960103398A AR003443A1 (es) 1994-07-15 1996-06-28 Procedimiento para la purificacion optica de preparaciones enantiomericamente enriquecidas de compuestos derivados de 2-sulfinil-bencimidazol
IS4406A IS1772B (is) 1994-07-15 1996-12-27 Aðferð við myndun útskiptra súlfoxíða
FI970102A FI117672B (sv) 1994-07-15 1997-01-10 Förfarande för syntetisering av substituerade sulfoxider
FI970102D FI117830B (sv) 1994-07-15 1997-01-10 Förfarande för syntetisering av substituerade sulfoxider
NO19970153A NO312101B1 (no) 1994-07-15 1997-01-14 Fremgangsmåte for syntese av substituerte sulfoksider, og slike produktforbindelser
HK98109230A HK1008331A1 (en) 1994-07-15 1998-07-17 Process for synthesis of substituted sulphoxides

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9402510A SE504459C2 (sv) 1994-07-15 1994-07-15 Förfarande för framställning av substituerade sulfoxider

Publications (3)

Publication Number Publication Date
SE9402510D0 true SE9402510D0 (sv) 1994-07-15
SE9402510L SE9402510L (sv) 1996-01-16
SE504459C2 SE504459C2 (sv) 1997-02-17

Family

ID=20394753

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9402510A SE504459C2 (sv) 1994-07-15 1994-07-15 Förfarande för framställning av substituerade sulfoxider

Country Status (42)

Country Link
US (1) US5948789A (sv)
EP (1) EP0773940B2 (sv)
JP (1) JP3795917B2 (sv)
KR (1) KR100356252B1 (sv)
CN (1) CN1070489C (sv)
AR (1) AR003443A1 (sv)
AT (1) ATE242233T1 (sv)
AU (1) AU688074B2 (sv)
BR (1) BR9508292A (sv)
CA (1) CA2193994C (sv)
CZ (1) CZ297987B6 (sv)
DE (1) DE69530987T3 (sv)
DK (1) DK0773940T4 (sv)
DZ (1) DZ1911A1 (sv)
EE (1) EE03354B1 (sv)
EG (1) EG24534A (sv)
ES (1) ES2199998T5 (sv)
FI (2) FI117830B (sv)
HK (1) HK1008331A1 (sv)
HR (1) HRP950401B1 (sv)
HU (1) HU226361B1 (sv)
IL (1) IL114477A (sv)
IS (1) IS1772B (sv)
MA (1) MA23611A1 (sv)
MX (1) MX9700358A (sv)
MY (1) MY113180A (sv)
NO (1) NO312101B1 (sv)
NZ (1) NZ289959A (sv)
PL (1) PL186342B1 (sv)
PT (1) PT773940E (sv)
RU (1) RU2157806C2 (sv)
SA (1) SA95160294B1 (sv)
SE (1) SE504459C2 (sv)
SI (1) SI0773940T2 (sv)
SK (1) SK284059B6 (sv)
TN (1) TNSN95081A1 (sv)
TR (1) TR199500861A2 (sv)
TW (1) TW372971B (sv)
UA (1) UA47409C2 (sv)
WO (1) WO1996002535A1 (sv)
YU (1) YU49475B (sv)
ZA (1) ZA955724B (sv)

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US6489346B1 (en) * 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6645988B2 (en) 1996-01-04 2003-11-11 Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
US6699885B2 (en) * 1996-01-04 2004-03-02 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and methods of using same
SE510650C2 (sv) * 1997-05-30 1999-06-14 Astra Ab Ny förening
US6747155B2 (en) 1997-05-30 2004-06-08 Astrazeneca Ab Process
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US6174548B1 (en) 1998-08-28 2001-01-16 Andrx Pharmaceuticals, Inc. Omeprazole formulation
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