PT1244650E - Derivados arilaminas e sua aplicacao como agentes anti-telomerase - Google Patents
Derivados arilaminas e sua aplicacao como agentes anti-telomeraseInfo
- Publication number
- PT1244650E PT1244650E PT00985339T PT00985339T PT1244650E PT 1244650 E PT1244650 E PT 1244650E PT 00985339 T PT00985339 T PT 00985339T PT 00985339 T PT00985339 T PT 00985339T PT 1244650 E PT1244650 E PT 1244650E
- Authority
- PT
- Portugal
- Prior art keywords
- arillamine
- derivatives
- application
- agents
- telomerase
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D251/00—Heterocyclic compounds containing 1,3,5-triazine rings
- C07D251/02—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
- C07D251/12—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D251/26—Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
- C07D251/40—Nitrogen atoms
- C07D251/54—Three nitrogen atoms
- C07D251/70—Other substituted melamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9915031A FR2801588B1 (fr) | 1999-11-29 | 1999-11-29 | Derives chimiques et leur application comme agent antitelomerase |
| FR0010561 | 2000-08-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT1244650E true PT1244650E (pt) | 2003-11-28 |
Family
ID=26212577
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT00985339T PT1244650E (pt) | 1999-11-29 | 2000-11-27 | Derivados arilaminas e sua aplicacao como agentes anti-telomerase |
Country Status (27)
| Country | Link |
|---|---|
| EP (1) | EP1244650B1 (pt) |
| JP (1) | JP2003515604A (pt) |
| KR (1) | KR20020058043A (pt) |
| CN (1) | CN1402722A (pt) |
| AT (1) | ATE243692T1 (pt) |
| AU (1) | AU2179001A (pt) |
| BG (1) | BG106753A (pt) |
| BR (1) | BR0015992A (pt) |
| CA (1) | CA2392507A1 (pt) |
| CO (1) | CO5251431A1 (pt) |
| CZ (1) | CZ20021849A3 (pt) |
| DE (1) | DE60003583T2 (pt) |
| DK (1) | DK1244650T3 (pt) |
| EA (1) | EA200200616A1 (pt) |
| EE (1) | EE200200263A (pt) |
| ES (1) | ES2202206T3 (pt) |
| HU (1) | HUP0204429A2 (pt) |
| IL (1) | IL149402A0 (pt) |
| MX (1) | MXPA02005276A (pt) |
| NO (1) | NO20022528L (pt) |
| PE (1) | PE20010912A1 (pt) |
| PL (1) | PL355667A1 (pt) |
| PT (1) | PT1244650E (pt) |
| SK (1) | SK7402002A3 (pt) |
| UY (1) | UY26456A1 (pt) |
| WO (1) | WO2001040218A1 (pt) |
| YU (1) | YU38102A (pt) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE396978T1 (de) | 1999-10-07 | 2008-06-15 | Amgen Inc | Triazin-kinase-hemmer |
| JP2003520855A (ja) * | 2000-01-28 | 2003-07-08 | アストラゼネカ アクチボラグ | 化学的化合物 |
| AU3704101A (en) | 2000-02-17 | 2001-08-27 | Amgen Inc | Kinase inhibitors |
| WO2002012194A1 (fr) * | 2000-08-08 | 2002-02-14 | Aventis Pharma S.A. | Derives de phenanthridine et leur application comme agents antitelomerases |
| US7105530B2 (en) * | 2000-12-21 | 2006-09-12 | Smithkline Beecham Corporation | Pyrimidineamines as angiogenesis modulators |
| FR2821355A1 (fr) * | 2001-02-23 | 2002-08-30 | Aventis Pharma Sa | Derives chimiques et leur application comme agent antitelomerase |
| US6887873B2 (en) | 2001-03-23 | 2005-05-03 | Aventis Pharma S.A. | Triazine derivatives and their application as antitelomerase agents |
| FR2822468B1 (fr) * | 2001-03-23 | 2008-06-20 | Aventis Pharma Sa | Derives chimiques et leur application comme agent anti-telomerase |
| CO5380035A1 (es) * | 2001-03-23 | 2004-03-31 | Aventis Pharma Sa | Derivados quimicos y su aplicacion como agente antitelomerasa |
| EP1401833A2 (fr) | 2001-05-28 | 2004-03-31 | Aventis Pharma S.A. | Derives chimiques et leur application comme agent antitelomerase |
| US7115617B2 (en) * | 2001-08-22 | 2006-10-03 | Amgen Inc. | Amino-substituted pyrimidinyl derivatives and methods of use |
| US6939874B2 (en) * | 2001-08-22 | 2005-09-06 | Amgen Inc. | Substituted pyrimidinyl derivatives and methods of use |
| US7169785B2 (en) | 2001-09-21 | 2007-01-30 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| US7132423B2 (en) | 2001-09-21 | 2006-11-07 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| US7173032B2 (en) | 2001-09-21 | 2007-02-06 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| US7112587B2 (en) | 2001-09-21 | 2006-09-26 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| US7163943B2 (en) | 2001-09-21 | 2007-01-16 | Reddy Us Therapeutics, Inc. | Methods and compositions of novel triazine compounds |
| JP2005519876A (ja) | 2001-11-27 | 2005-07-07 | メルク エンド カムパニー インコーポレーテッド | ２−アミノキノリン化合物 |
| BR0314195A (pt) * | 2002-09-10 | 2005-07-26 | Pharmacia Italia Spa | Derivados de piridina substituìda como agentes antitumorais |
| AU2003275726A1 (en) * | 2002-10-24 | 2004-05-13 | Chong Kun Dang Pharmaceutical Corp. | 2 - substituted heterocyclic compounds and antitumor composition comprising the same |
| FR2850970B1 (fr) * | 2003-02-07 | 2006-07-07 | Aventis Pharma Sa | Derives chimiques se liant de maniere tres specifique aux structures d'adn en g-quadruplexe et leur application comme agent anticancereux specifique |
| EP1691812A4 (en) * | 2003-11-20 | 2010-01-13 | Childrens Hosp Medical Center | GTPASE INHIBITORS AND METHOD OF USE |
| US7335770B2 (en) | 2004-03-24 | 2008-02-26 | Reddy U5 Therapeutics, Inc. | Triazine compounds and their analogs, compositions, and methods |
| WO2007049057A2 (en) * | 2005-10-28 | 2007-05-03 | Iti Scotland Limited | Novel fluorescent dyes and uses thereof |
| US7713987B2 (en) | 2005-12-06 | 2010-05-11 | Rigel Pharmaceuticals, Inc. | Pyrimidine-2,4-diamines and their uses |
| KR100761869B1 (ko) * | 2006-07-07 | 2007-10-04 | 김현기 | 트리아진 유도체 화합물 및 이를 포함하는 암 치료용조성물 |
| EP2046763A2 (en) * | 2006-07-31 | 2009-04-15 | Praecis Pharmaceuticals Incorporated | Aurora kinase inhibitors from an encoded small molecule library |
| JP5325517B2 (ja) * | 2007-10-12 | 2013-10-23 | 住友化学株式会社 | ジベンゾオキセピン化合物の精製方法 |
| JP2009102249A (ja) * | 2007-10-22 | 2009-05-14 | Sumitomo Chemical Co Ltd | ジベンゾオキセピン化合物の結晶の製造方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9206768D0 (en) * | 1992-03-27 | 1992-05-13 | Jarman Michael | New compounds for use in the treatment of cancer |
| US5770613A (en) * | 1995-09-29 | 1998-06-23 | Geron Corporation | Telomerase inhibitors |
| JPH1160573A (ja) * | 1997-08-22 | 1999-03-02 | Nippon Kayaku Co Ltd | トリアジン誘導体及びテロメラーゼ阻害剤 |
| ATE244241T1 (de) * | 1998-02-04 | 2003-07-15 | Univ Texas | Hemmung der menschlichen telomerase durch g- quadruplex interaktionverbindung |
| DE19812879A1 (de) * | 1998-03-24 | 1999-09-30 | Bayer Ag | Substituierte 2,4-Diamino-1,3,5-triazine |
-
2000
- 2000-11-27 CA CA002392507A patent/CA2392507A1/fr not_active Abandoned
- 2000-11-27 MX MXPA02005276A patent/MXPA02005276A/es unknown
- 2000-11-27 YU YU38102A patent/YU38102A/sh unknown
- 2000-11-27 ES ES00985339T patent/ES2202206T3/es not_active Expired - Lifetime
- 2000-11-27 EE EEP200200263A patent/EE200200263A/xx unknown
- 2000-11-27 SK SK740-2002A patent/SK7402002A3/sk unknown
- 2000-11-27 EA EA200200616A patent/EA200200616A1/ru unknown
- 2000-11-27 KR KR1020027006786A patent/KR20020058043A/ko not_active Application Discontinuation
- 2000-11-27 AU AU21790/01A patent/AU2179001A/en not_active Abandoned
- 2000-11-27 BR BR0015992-1A patent/BR0015992A/pt not_active IP Right Cessation
- 2000-11-27 DK DK00985339T patent/DK1244650T3/da active
- 2000-11-27 IL IL14940200A patent/IL149402A0/xx unknown
- 2000-11-27 EP EP00985339A patent/EP1244650B1/fr not_active Expired - Lifetime
- 2000-11-27 DE DE60003583T patent/DE60003583T2/de not_active Expired - Fee Related
- 2000-11-27 JP JP2001541902A patent/JP2003515604A/ja not_active Withdrawn
- 2000-11-27 CZ CZ20021849A patent/CZ20021849A3/cs unknown
- 2000-11-27 CN CN00816440A patent/CN1402722A/zh active Pending
- 2000-11-27 AT AT00985339T patent/ATE243692T1/de not_active IP Right Cessation
- 2000-11-27 PL PL00355667A patent/PL355667A1/xx not_active Application Discontinuation
- 2000-11-27 WO PCT/FR2000/003310 patent/WO2001040218A1/fr not_active Application Discontinuation
- 2000-11-27 HU HU0204429A patent/HUP0204429A2/hu unknown
- 2000-11-27 PT PT00985339T patent/PT1244650E/pt unknown
- 2000-11-28 CO CO00090981A patent/CO5251431A1/es not_active Application Discontinuation
- 2000-11-28 PE PE2000001265A patent/PE20010912A1/es not_active Application Discontinuation
- 2000-11-28 UY UY26456A patent/UY26456A1/es not_active Application Discontinuation
-
2002
- 2002-05-28 NO NO20022528A patent/NO20022528L/no not_active Application Discontinuation
- 2002-05-29 BG BG106753A patent/BG106753A/bg unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2179001A (en) | 2001-06-12 |
| EA200200616A1 (ru) | 2002-10-31 |
| PL355667A1 (en) | 2004-05-04 |
| CZ20021849A3 (cs) | 2002-08-14 |
| DE60003583D1 (de) | 2003-07-31 |
| EP1244650B1 (fr) | 2003-06-25 |
| CO5251431A1 (es) | 2003-02-28 |
| BR0015992A (pt) | 2002-08-06 |
| HUP0204429A2 (hu) | 2003-04-28 |
| NO20022528D0 (no) | 2002-05-28 |
| SK7402002A3 (en) | 2002-11-06 |
| CA2392507A1 (fr) | 2001-06-07 |
| WO2001040218A1 (fr) | 2001-06-07 |
| EE200200263A (et) | 2003-06-16 |
| CN1402722A (zh) | 2003-03-12 |
| KR20020058043A (ko) | 2002-07-12 |
| MXPA02005276A (es) | 2002-11-07 |
| DE60003583T2 (de) | 2004-05-13 |
| UY26456A1 (es) | 2001-06-29 |
| ATE243692T1 (de) | 2003-07-15 |
| IL149402A0 (en) | 2002-11-10 |
| YU38102A (sh) | 2004-12-31 |
| NO20022528L (no) | 2002-05-28 |
| JP2003515604A (ja) | 2003-05-07 |
| ES2202206T3 (es) | 2004-04-01 |
| DK1244650T3 (da) | 2003-10-20 |
| BG106753A (bg) | 2003-02-28 |
| PE20010912A1 (es) | 2001-09-01 |
| EP1244650A1 (fr) | 2002-10-02 |
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