NO973198L - Aryl- og heteroarylpurinforbindelser - Google Patents
Aryl- og heteroarylpurinforbindelserInfo
- Publication number
- NO973198L NO973198L NO973198A NO973198A NO973198L NO 973198 L NO973198 L NO 973198L NO 973198 A NO973198 A NO 973198A NO 973198 A NO973198 A NO 973198A NO 973198 L NO973198 L NO 973198L
- Authority
- NO
- Norway
- Prior art keywords
- alkyl
- alkoxy
- halogen
- ring
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/28—Oxygen atom
- C07D473/30—Oxygen atom attached in position 6, e.g. hypoxanthine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
- C07D473/34—Nitrogen atom attached in position 6, e.g. adenine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/36—Sulfur atom
- C07D473/38—Sulfur atom attached in position 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Transplantation (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9523242.7A GB9523242D0 (en) | 1995-11-14 | 1995-11-14 | Aryl and heteroaryl purine compounds |
GBGB9524131.1A GB9524131D0 (en) | 1995-11-24 | 1995-11-24 | Pyrido-pyrimidine compounds as tyrosine kinase inhibitors |
PCT/EP1996/004460 WO1997018212A1 (en) | 1995-11-14 | 1996-10-14 | Aryl and heteroaryl purine compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
NO973198D0 NO973198D0 (no) | 1997-07-09 |
NO973198L true NO973198L (no) | 1997-07-09 |
Family
ID=26308112
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO973198A NO973198L (no) | 1995-11-14 | 1997-07-09 | Aryl- og heteroarylpurinforbindelser |
Country Status (17)
Country | Link |
---|---|
US (1) | US5965563A (es) |
EP (1) | EP0802914B1 (es) |
JP (1) | JPH10512896A (es) |
CN (1) | CN1168138A (es) |
AR (1) | AR004320A1 (es) |
AT (1) | ATE201873T1 (es) |
AU (1) | AU7292096A (es) |
BR (1) | BR9607089A (es) |
CA (1) | CA2209598C (es) |
DE (1) | DE69613211T2 (es) |
EA (1) | EA000072B1 (es) |
ES (1) | ES2159760T3 (es) |
HU (1) | HUP9801177A3 (es) |
IL (1) | IL121090A0 (es) |
NO (1) | NO973198L (es) |
PL (1) | PL321296A1 (es) |
WO (1) | WO1997018212A1 (es) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL112249A (en) | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
TW321649B (es) * | 1994-11-12 | 1997-12-01 | Zeneca Ltd | |
GB9424233D0 (en) * | 1994-11-30 | 1995-01-18 | Zeneca Ltd | Quinazoline derivatives |
GB9508537D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivatives |
DE69613367T2 (de) * | 1995-04-27 | 2002-04-18 | Astrazeneca Ab, Soedertaelje | Chinazolin derivate |
GB9508535D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quinazoline derivative |
GB9508565D0 (en) * | 1995-04-27 | 1995-06-14 | Zeneca Ltd | Quiazoline derivative |
GB9624482D0 (en) * | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
WO1997030035A1 (en) | 1996-02-13 | 1997-08-21 | Zeneca Limited | Quinazoline derivatives as vegf inhibitors |
GB9603097D0 (en) * | 1996-02-14 | 1996-04-10 | Zeneca Ltd | Quinazoline compounds |
WO1997032856A1 (en) | 1996-03-05 | 1997-09-12 | Zeneca Limited | 4-anilinoquinazoline derivatives |
ATE213730T1 (de) | 1996-04-12 | 2002-03-15 | Warner Lambert Co | Umkehrbare inhibitoren von tyrosin kinasen |
HRP970371A2 (en) * | 1996-07-13 | 1998-08-31 | Kathryn Jane Smith | Heterocyclic compounds |
US5866702A (en) * | 1996-08-02 | 1999-02-02 | Cv Therapeutics, Incorporation | Purine inhibitors of cyclin dependent kinase 2 |
WO1999002162A1 (en) * | 1997-07-12 | 1999-01-21 | Cancer Research Campaign Technology Limited | Cyclin dependent kinase inhibiting purine derivatives |
RS49779B (sr) | 1998-01-12 | 2008-06-05 | Glaxo Group Limited, | Biciklična heteroaromatična jedinjenja kao inhibitori protein tirozin kinaze |
PA8474101A1 (es) | 1998-06-19 | 2000-09-29 | Pfizer Prod Inc | Compuestos de pirrolo [2,3-d] pirimidina |
TW505646B (en) | 1998-06-19 | 2002-10-11 | Pfizer Prod Inc | Pyrrolo [2,3-d] pyrimidine compounds |
WO2001004111A1 (en) | 1999-07-09 | 2001-01-18 | Glaxo Group Limited | Anilinoquinazolines as protein tyrosine kinase inhibitors |
US6933299B1 (en) | 1999-07-09 | 2005-08-23 | Smithkline Beecham Corporation | Anilinoquinazolines as protein tyrosine kinase inhibitors |
UA72946C2 (uk) | 1999-11-05 | 2005-05-16 | Астразенека Аб | Похідні хіназоліну як інгібітори васкулярного ендотеліального фактора росту (vegf) |
PL218519B1 (pl) | 1999-12-10 | 2014-12-31 | Pfizer Prod Inc | Związki pirolo [2,3-d] pirymidynowe, środek farmaceutyczny zawierający te związki oraz ich zastosowanie |
SK17342002A3 (sk) | 2000-06-26 | 2004-06-08 | Pfizer Products Inc. | Derivát pyrolo[2,3-d]pyrimidínu ako činidlo potlačujúce imunitu |
US7301023B2 (en) | 2001-05-31 | 2007-11-27 | Pfizer Inc. | Chiral salt resolution |
AU2002346729A1 (en) * | 2001-12-20 | 2003-07-09 | Bristol-Myers Squibb Company | Barbituric acid derivatives as inhibitors of tnf-$g(a) converting enzyme (tace) and/or matrix metalloproteinases |
EP1352910A1 (en) * | 2002-04-10 | 2003-10-15 | Grünenthal GmbH | New analogs of nitrobenzylthioinosine |
EP1572213A1 (en) | 2002-11-26 | 2005-09-14 | Pfizer Products Inc. | Method of treatment of transplant rejection |
MXPA06001758A (es) * | 2003-08-15 | 2006-08-11 | Irm Llc | Anilino purinas sustituidas en la posicion 6 utiles como inhibidores de rtk. |
US7626030B2 (en) | 2004-01-23 | 2009-12-01 | Amgen Inc. | Compounds and methods of use |
KR20070026390A (ko) * | 2004-01-23 | 2007-03-08 | 암젠 인코포레이션 | 화합물 및 사용방법 |
ES2294400T3 (es) * | 2004-06-29 | 2008-04-01 | Grunenthal Gmbh | Nuevos analogos de notrobenciltioinosina. |
EP1827434B1 (en) * | 2004-11-30 | 2014-01-15 | Amgen Inc. | Quinolines and quinazoline analogs and their use as medicaments for treating cancer |
JO2787B1 (en) * | 2005-04-27 | 2014-03-15 | امجين إنك, | Alternative amide derivatives and methods of use |
WO2007081517A2 (en) | 2005-12-21 | 2007-07-19 | Abbott Laboratories | Anti-viral compounds |
JP2009521479A (ja) * | 2005-12-21 | 2009-06-04 | アボット・ラボラトリーズ | 抗ウイルス化合物 |
TWI399380B (zh) * | 2006-12-20 | 2013-06-21 | Abbott Lab | 抗病毒化合物 |
ES2417009T3 (es) * | 2007-10-29 | 2013-08-05 | Amgen, Inc | Derivados de benzomorfolina y métodos de uso |
WO2010020905A1 (en) | 2008-08-20 | 2010-02-25 | Pfizer Inc. | Pyrrolo[2,3-d]pyrimidine compounds |
DE102011111400A1 (de) * | 2011-08-23 | 2013-02-28 | Merck Patent Gmbh | Bicyclische heteroaromatische Verbindungen |
ES2592404T3 (es) | 2012-05-21 | 2016-11-30 | Bayer Pharma Aktiengesellschaft | Benzotienopirimidinas sustituidas |
TW201412740A (zh) * | 2012-09-20 | 2014-04-01 | Bayer Pharma AG | 經取代之吡咯并嘧啶胺基苯并噻唑酮 |
ES2686909B1 (es) | 2017-03-22 | 2019-08-16 | Consejo Superior Investigacion | Compuestos inhibidores de cdc-7 y su uso para el tratamiento de patologias neurologicas |
FR3066761B1 (fr) * | 2017-05-23 | 2020-10-30 | Centre Nat Rech Scient | Nouveaux composes inhibiteurs des canaux ioniques |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB828522A (en) * | 1956-11-02 | 1960-02-17 | Geigy Ag J R | Purine derivatives and a process for the preparation thereof |
US3112192A (en) * | 1960-09-19 | 1963-11-26 | Shell Oil Co | Preservation of cut flowers |
AU575438B2 (en) * | 1984-10-26 | 1988-07-28 | Warner-Lambert Company | N6 - substituted deoxyribose analogues of adenosines |
US4751292A (en) * | 1985-07-02 | 1988-06-14 | The Plant Cell Research Institute, Inc. | Adamantyl purines |
DE3529497A1 (de) * | 1985-08-17 | 1987-02-26 | Boehringer Mannheim Gmbh | N(pfeil hoch)6(pfeil hoch)-disubstituierte purinderivate, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
EP0457773A4 (en) * | 1989-01-31 | 1993-03-10 | Whitby Research Incorporated | N?6 -substituted 9-methyladenines: a new class of adenosine receptor antagonists |
US5034393A (en) * | 1989-07-27 | 1991-07-23 | Dowelanco | Fungicidal use of pyridopyrimidine, pteridine, pyrimidopyrimidine, pyrimidopyridazine, and pyrimido-1,2,4-triazine derivatives |
UA41297C2 (uk) * | 1991-11-25 | 2001-09-17 | Пфайзер, Інк. | Похідні індолу, фармацевтична композиція і спосіб лікування |
US5670501A (en) * | 1994-09-01 | 1997-09-23 | Discovery Therapeutics, Inc. | N-substituted 9-alkyladenines |
-
1996
- 1996-10-14 AT AT96934673T patent/ATE201873T1/de not_active IP Right Cessation
- 1996-10-14 PL PL96321296A patent/PL321296A1/xx unknown
- 1996-10-14 EP EP96934673A patent/EP0802914B1/en not_active Expired - Lifetime
- 1996-10-14 DE DE69613211T patent/DE69613211T2/de not_active Expired - Fee Related
- 1996-10-14 WO PCT/EP1996/004460 patent/WO1997018212A1/en not_active Application Discontinuation
- 1996-10-14 IL IL12109096A patent/IL121090A0/xx unknown
- 1996-10-14 HU HU9801177A patent/HUP9801177A3/hu unknown
- 1996-10-14 CN CN96191448A patent/CN1168138A/zh active Pending
- 1996-10-14 BR BR9607089A patent/BR9607089A/pt not_active Application Discontinuation
- 1996-10-14 ES ES96934673T patent/ES2159760T3/es not_active Expired - Lifetime
- 1996-10-14 AU AU72920/96A patent/AU7292096A/en not_active Abandoned
- 1996-10-14 US US08/860,717 patent/US5965563A/en not_active Expired - Fee Related
- 1996-10-14 EA EA199700107A patent/EA000072B1/ru not_active IP Right Cessation
- 1996-10-14 CA CA002209598A patent/CA2209598C/en not_active Expired - Fee Related
- 1996-10-14 JP JP9518527A patent/JPH10512896A/ja not_active Ceased
- 1996-11-13 AR ARP960105153A patent/AR004320A1/es unknown
-
1997
- 1997-07-09 NO NO973198A patent/NO973198L/no unknown
Also Published As
Publication number | Publication date |
---|---|
US5965563A (en) | 1999-10-12 |
ES2159760T3 (es) | 2001-10-16 |
NO973198D0 (no) | 1997-07-09 |
IL121090A0 (en) | 1997-11-20 |
ATE201873T1 (de) | 2001-06-15 |
AR004320A1 (es) | 1998-11-04 |
JPH10512896A (ja) | 1998-12-08 |
DE69613211T2 (de) | 2001-11-15 |
CA2209598A1 (en) | 1997-05-22 |
CA2209598C (en) | 2005-06-07 |
DE69613211D1 (de) | 2001-07-12 |
BR9607089A (pt) | 1997-11-11 |
EP0802914B1 (en) | 2001-06-06 |
EP0802914A1 (en) | 1997-10-29 |
HUP9801177A2 (hu) | 1998-09-28 |
MX9705010A (es) | 1997-10-31 |
AU7292096A (en) | 1997-06-05 |
HUP9801177A3 (en) | 1998-11-30 |
CN1168138A (zh) | 1997-12-17 |
PL321296A1 (en) | 1997-12-08 |
EA000072B1 (ru) | 1998-06-25 |
EA199700107A1 (ru) | 1997-12-30 |
WO1997018212A1 (en) | 1997-05-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
NO973198L (no) | Aryl- og heteroarylpurinforbindelser | |
CY1117132T1 (el) | Παραγωγο θειαζολιου | |
LU92113I2 (fr) | Perampanel et ses dérivés pharmaceutiquement acceptables (FYCOMPA) | |
ATE373656T1 (de) | Azaindolderivate, verfahren zu ihrer herstellung und ihre verwendung als antitumormittel | |
KR950008512A (ko) | 이미다조피리딘 유도체의 제조방법 | |
NO20080917L (no) | Nytt heterocyklidenacetamidderivat | |
GB1495526A (en) | Chroman derivatives | |
DE69824332D1 (de) | N-Aryl-piperidinderivate und ihre Verwendung als 5-HT1B-Rezeptorliganden | |
YU19890A (sh) | Derivati tetrahidrobenzimidazola i postupak za njihovo dobijanje | |
AR017189A1 (es) | Antagonistas del receptor de trombina triciclico sustituido, composicion farmaceutica que lo contiene y su uso para la manufactura de un medicamento | |
EA199801013A1 (ru) | Производные дистамицина, способ их получения и применение в качестве противоопухолевых и противовирусных агентов | |
ES2039221T3 (es) | Procedimiento para producir derivados de piridazinona. | |
EP1473295A4 (en) | BICYCLIC FUSIONED PYRIMIDINE DERIVATIVES | |
ATE194982T1 (de) | Benzoxazepin-derivate als cholinesterase- inhibitoren | |
PL91738B1 (es) | ||
AR036734A1 (es) | Derivados de 8-amino-[1,2,4]triazolo[1,5-a]piridina-6-carboxilico | |
IS2282B (is) | Ný lyfefnasambönd með alfa2viðtakavirkni | |
ATE58902T1 (de) | Penem-derivate. | |
ATE279191T1 (de) | Trizyklische dihydrobenzofurane, verfahren zu deren herstellung und mittel | |
YU11494A (sh) | Postupak za dobijanje derivata piperazinilkamforsulfonila kao antagonista oksitocina | |
NO20044331L (no) | Kondenserte bicykliske pyrimidinderivater | |
DE69319900D1 (de) | N,n'-disubstituierte amidderivate | |
EA199800720A1 (ru) | Гетероциклические производные эрголина в качестве лигандов 5-htia рецептора | |
DE69626624D1 (de) | Medikamente gegen trhombocytopenie | |
NO955071L (no) | abeo-Ergolin-derivater som 5HT1A-ligander |