NO319132B1 - Okt produksjon av utsondrede proteiner fra rekombinante eukaryote-celler - Google Patents

Okt produksjon av utsondrede proteiner fra rekombinante eukaryote-celler Download PDF

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Publication number
NO319132B1
NO319132B1 NO19951315A NO951315A NO319132B1 NO 319132 B1 NO319132 B1 NO 319132B1 NO 19951315 A NO19951315 A NO 19951315A NO 951315 A NO951315 A NO 951315A NO 319132 B1 NO319132 B1 NO 319132B1
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NO
Norway
Prior art keywords
gene
protein
sso
vector
cells
Prior art date
Application number
NO19951315A
Other languages
English (en)
Norwegian (no)
Other versions
NO951315L (no
NO951315D0 (no
Inventor
Merja Penttila
Sirkka Keranen
Markku Aalto
Mika Outola
Hans Ronne
Original Assignee
Valtion Teknillinen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Valtion Teknillinen filed Critical Valtion Teknillinen
Publication of NO951315D0 publication Critical patent/NO951315D0/no
Publication of NO951315L publication Critical patent/NO951315L/no
Publication of NO319132B1 publication Critical patent/NO319132B1/no

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2414Alpha-amylase (3.2.1.1.)
    • C12N9/2417Alpha-amylase (3.2.1.1.) from microbiological source
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67General methods for enhancing the expression
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
NO19951315A 1992-10-06 1995-04-05 Okt produksjon av utsondrede proteiner fra rekombinante eukaryote-celler NO319132B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI924494A FI924494A0 (fi) 1992-10-06 1992-10-06 Oekad produktion av avsoendrarde proteiner i eukaryotiska rekombinantceller
PCT/FI1993/000402 WO1994008024A1 (en) 1992-10-06 1993-10-06 Increased production of secreted proteins by recombinant eukaryotic cells

Publications (3)

Publication Number Publication Date
NO951315D0 NO951315D0 (no) 1995-04-05
NO951315L NO951315L (no) 1995-06-06
NO319132B1 true NO319132B1 (no) 2005-06-20

Family

ID=8535988

Family Applications (1)

Application Number Title Priority Date Filing Date
NO19951315A NO319132B1 (no) 1992-10-06 1995-04-05 Okt produksjon av utsondrede proteiner fra rekombinante eukaryote-celler

Country Status (14)

Country Link
US (1) US5789193A (da)
EP (1) EP0665890B1 (da)
JP (1) JP3638599B2 (da)
AT (1) ATE254663T1 (da)
AU (1) AU678402B2 (da)
CA (1) CA2146240C (da)
DE (1) DE69333304T2 (da)
DK (1) DK0665890T3 (da)
EE (1) EE03074B1 (da)
ES (1) ES2211870T3 (da)
FI (2) FI924494A0 (da)
NO (1) NO319132B1 (da)
NZ (1) NZ256425A (da)
WO (1) WO1994008024A1 (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5922561A (en) * 1994-10-03 1999-07-13 Novo Nordisk Biotech, Inc. Genes encoding signal recognition particle of Aspergillus niger
DE19920712A1 (de) * 1999-05-05 2000-11-09 Rhein Biotech Proz & Prod Gmbh Verfahren zum Herstellen eines rekombinanten Proteines
US7678570B2 (en) 2004-03-01 2010-03-16 Kitakyushu Foundation For The Advancement Of Industry, Science And Technology Human cell strains for protein production, provided by selecting strains with high intracellular protein and mutating with carcinogens
US20090247609A1 (en) * 2007-12-20 2009-10-01 Hitto Kaufmann Sm-protein based secretion engineering
EP3020273B1 (en) * 2014-11-17 2018-07-04 Competence Centre on Health Technologies A method of producing biotechnological drugs using transgenic bovine animals
EP3784791A1 (en) 2018-04-23 2021-03-03 DuPont Nutrition Biosciences ApS Increasing export of 2' fucosyllactose from microbial cells through the expression of a heterologous nucleic acid
EP4194560A1 (en) 2021-12-08 2023-06-14 European Molecular Biology Laboratory Improved production of secreted proteins in fungal cells
CN114717124B (zh) * 2022-04-19 2024-07-12 天津科技大学 一株高产麦角甾醇的酿酒酵母工程菌株、构建方法及应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0284044B1 (en) * 1987-03-23 1994-03-23 Zymogenetics, Inc. High level expression in yeast

Also Published As

Publication number Publication date
US5789193A (en) 1998-08-04
DE69333304T2 (de) 2004-08-26
NO951315L (no) 1995-06-06
EP0665890B1 (en) 2003-11-19
JP3638599B2 (ja) 2005-04-13
ES2211870T3 (es) 2004-07-16
FI951633A0 (fi) 1995-04-05
EP0665890A1 (en) 1995-08-09
FI114482B (fi) 2004-10-29
FI924494A0 (fi) 1992-10-06
ATE254663T1 (de) 2003-12-15
JPH08501695A (ja) 1996-02-27
WO1994008024A1 (en) 1994-04-14
FI951633A (fi) 1995-04-05
CA2146240C (en) 2007-05-01
DK0665890T3 (da) 2004-03-08
NZ256425A (en) 1996-08-27
DE69333304D1 (de) 2003-12-24
EE03074B1 (et) 1998-02-16
AU678402B2 (en) 1997-05-29
AU5112793A (en) 1994-04-26
CA2146240A1 (en) 1994-04-14
NO951315D0 (no) 1995-04-05

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