NO20072142L - Mellomprodukter for fremstilling av heterocyklylalkylpiperidinderivater og forbindelser for fremstilling av disse - Google Patents

Mellomprodukter for fremstilling av heterocyklylalkylpiperidinderivater og forbindelser for fremstilling av disse

Info

Publication number
NO20072142L
NO20072142L NO20072142A NO20072142A NO20072142L NO 20072142 L NO20072142 L NO 20072142L NO 20072142 A NO20072142 A NO 20072142A NO 20072142 A NO20072142 A NO 20072142A NO 20072142 L NO20072142 L NO 20072142L
Authority
NO
Norway
Prior art keywords
preparation
intermediates
compounds
methoxyquinoline
chloro
Prior art date
Application number
NO20072142A
Other languages
English (en)
Inventor
Jean-Luc Malleron
Serge Mignani
Michel Evers
Guy Pantel
Michel Tabart
Fabrice Viviani
Eric Bacque
Jean-Christophe Carry
Youssef El-Ahmad
Philippe Hubert
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of NO20072142L publication Critical patent/NO20072142L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Abstract

Det beskrives en hvilken som helst fiorbindelse valgt blant 4-klor-3 -fluor-6-metoksykinolin, 4-brom-3 -fluor-6-metoksykinolin, 4-j od-3 -fluor-6-metoksykinolin, 4-brom-3 -klor-6-metoksykinolin, 4-j od-3 -klor-6-metoksykinolin, 4-hydroksy-3 -klor-6-metoksykinolin og 3-fluor-6-metoksykinolin.
NO20072142A 2000-11-15 2007-04-25 Mellomprodukter for fremstilling av heterocyklylalkylpiperidinderivater og forbindelser for fremstilling av disse NO20072142L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0014738A FR2816618B1 (fr) 2000-11-15 2000-11-15 Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
PCT/FR2001/003559 WO2002040474A2 (fr) 2000-11-15 2001-11-14 Derives heterocyclylalcoyl piperidine et leur application comme antimicrobiens

Publications (1)

Publication Number Publication Date
NO20072142L true NO20072142L (no) 2007-04-25

Family

ID=8856503

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20032187A NO20032187L (no) 2000-11-15 2003-05-14 Heterocyklylalkylpiperidinderivater, deres fremstilling samt preparater inneholdende forbindelsene
NO20072142A NO20072142L (no) 2000-11-15 2007-04-25 Mellomprodukter for fremstilling av heterocyklylalkylpiperidinderivater og forbindelser for fremstilling av disse

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20032187A NO20032187L (no) 2000-11-15 2003-05-14 Heterocyklylalkylpiperidinderivater, deres fremstilling samt preparater inneholdende forbindelsene

Country Status (28)

Country Link
EP (2) EP1695964A1 (no)
JP (1) JP2004514661A (no)
KR (1) KR100849608B1 (no)
CN (1) CN1483031A (no)
AR (1) AR034006A1 (no)
AT (1) ATE337311T1 (no)
AU (2) AU2002218365B2 (no)
BG (1) BG107793A (no)
BR (1) BR0115312A (no)
CA (1) CA2429311A1 (no)
CZ (1) CZ20031316A3 (no)
DE (1) DE60122567T2 (no)
DK (1) DK1337529T3 (no)
EA (1) EA200300568A1 (no)
EE (1) EE200300207A (no)
ES (1) ES2271119T3 (no)
FR (1) FR2816618B1 (no)
HR (1) HRP20030379A2 (no)
HU (1) HUP0303758A3 (no)
IL (1) IL155841A0 (no)
NO (2) NO20032187L (no)
PL (1) PL363004A1 (no)
PT (1) PT1337529E (no)
SK (1) SK5822003A3 (no)
TN (1) TNSN01160A1 (no)
WO (1) WO2002040474A2 (no)
YU (1) YU46803A (no)
ZA (1) ZA200303794B (no)

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DE60125373T2 (de) 2000-07-26 2007-10-18 Smithkline Beecham P.L.C., Brentford Aminopiperidin chinoline und ihre azaisosteren analoga mit antibakterieller wirkung
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
WO2003064431A2 (en) 2002-01-29 2003-08-07 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
EP2181996A1 (en) 2002-01-29 2010-05-05 Glaxo Group Limited Aminopiperidine derivatives
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
AR040335A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de ciclohexano o ciclohexeno, uso del mismo para preparar un medicamento, composicion farmaceutica que lo comprende, procedimiento y compuestos intermediarios de utilidad para preparar dicho compuesto
FR2842807A1 (fr) * 2002-07-23 2004-01-30 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, procede et intermediaires de preparation et compositions les renfermant
GB0217294D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicaments
FR2844270B1 (fr) 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
FR2844268B1 (fr) 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
DE10256405A1 (de) * 2002-12-02 2004-06-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen, die Topoisomerase IV inhibieren
JP4704755B2 (ja) 2002-11-05 2011-06-22 グラクソスミスクライン・リミテッド・ライアビリティ・カンパニー 抗菌剤
EP1567520B1 (en) 2002-12-04 2008-10-15 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
FR2852954B1 (fr) * 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
US7232833B2 (en) 2003-03-28 2007-06-19 Novexel 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
FR2862301B1 (fr) * 2003-11-17 2007-12-21 Aventis Pharma Sa Nouveau procede de preparation de quinoleines 3-fluorees
FR2867472B1 (fr) * 2004-03-12 2008-07-18 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
WO2006081178A2 (en) 2005-01-25 2006-08-03 Glaxo Group Limited Antibacterial agents
US7605169B2 (en) 2005-01-25 2009-10-20 Glaxo Group Limited Antibacterial agents
JP2008528587A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
EP1846418A4 (en) 2005-01-25 2009-12-23 Glaxo Group Ltd ANTIBACTERIAL ACTIVE SUBSTANCES
JP2008531709A (ja) 2005-03-01 2008-08-14 ワイス シンノリン化合物および肝臓ｘ受容体調節物質としてのそれらの使用
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
CA2635126A1 (en) 2006-01-26 2007-08-02 Actelion Pharmaceuticals Ltd Tetrahydropyrane antibiotics
WO2007115947A1 (en) 2006-04-06 2007-10-18 Glaxo Group Limited Pyrrolo-quinoxalinone derivatives as antibacterials
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
ATE520687T1 (de) 2007-06-15 2011-09-15 Actelion Pharmaceuticals Ltd 3-amino-6-(1-amino-ethyl)-tetrahydropyranderiva e
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
EP2379554B1 (en) 2009-01-15 2015-11-11 Glaxo Group Limited Naphthyridin-2(1h)-one compounds useful as antibacterials
JP6389174B2 (ja) * 2012-08-15 2018-09-12 グラクソ グループ リミテッドＧｌａｘｏ Ｇｒｏｕｐ Ｌｉｍｉｔｅｄ 化学的方法
EA031589B1 (ru) 2014-08-22 2019-01-31 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Трициклические азотсодержащие соединения для лечения инфекции, вызываемой neisseria gonorrhoeae
WO2016138988A1 (en) * 2015-03-02 2016-09-09 University Of Copenhagen Piperazine inhibitors of bacterial gyrase and topoisomerase iv
UY36851A (es) 2015-08-16 2017-03-31 Glaxosmithkline Ip Dev Ltd Compuestos para uso en aplicaciones antibacterianas

Family Cites Families (6)

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Publication number Priority date Publication date Assignee Title
NL7908031A (nl) 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
JPH0239546A (ja) 1988-07-29 1990-02-08 Origin Electric Co Ltd 混成集積回路の製造方法
AU623474B2 (en) 1989-01-16 1992-05-14 Laboratoire Roger Bellon New benzo(1,8)naphthyridine derivatives, their preparation and compositions containing them
ES2201674T3 (es) * 1998-01-26 2004-03-16 Smithkline Beecham Plc Derivados de quinolina con propiedades antibacterianas.
AU2437900A (en) * 1999-01-20 2000-08-07 Smithkline Beecham Plc Piperidinylquinolines as protein tyrosine kinase inhibitors
FR2852954B1 (fr) * 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
WO2002040474A3 (fr) 2002-10-31
BR0115312A (pt) 2003-09-23
EA200300568A1 (ru) 2003-12-25
FR2816618A1 (fr) 2002-05-17
SK5822003A3 (en) 2004-06-08
BG107793A (bg) 2004-08-31
EP1337529A2 (fr) 2003-08-27
HRP20030379A2 (en) 2005-04-30
PT1337529E (pt) 2006-12-29
ZA200303794B (en) 2004-06-29
KR20030060934A (ko) 2003-07-16
KR100849608B1 (ko) 2008-07-31
DE60122567T2 (de) 2007-08-23
CA2429311A1 (en) 2002-05-23
ES2271119T3 (es) 2007-04-16
CZ20031316A3 (cs) 2003-10-15
EP1337529B1 (fr) 2006-08-23
AU1836502A (en) 2002-05-27
DK1337529T3 (da) 2006-12-18
WO2002040474A2 (fr) 2002-05-23
PL363004A1 (en) 2004-11-15
YU46803A (sh) 2006-05-25
JP2004514661A (ja) 2004-05-20
AU2002218365B2 (en) 2007-07-05
EE200300207A (et) 2003-08-15
FR2816618B1 (fr) 2002-12-27
HUP0303758A3 (en) 2009-08-28
HUP0303758A2 (hu) 2004-03-01
IL155841A0 (en) 2003-12-23
NO20032187L (no) 2003-06-26
AR034006A1 (es) 2004-01-21
NO20032187D0 (no) 2003-05-14
EP1695964A1 (fr) 2006-08-30
CN1483031A (zh) 2004-03-17
TNSN01160A1 (fr) 2005-11-10
ATE337311T1 (de) 2006-09-15
DE60122567D1 (de) 2006-10-05

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Legal Events

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