NO20034660D0 - Spiropyrazolforbindelser - Google Patents

Spiropyrazolforbindelser

Info

Publication number
NO20034660D0
NO20034660D0 NO20034660A NO20034660A NO20034660D0 NO 20034660 D0 NO20034660 D0 NO 20034660D0 NO 20034660 A NO20034660 A NO 20034660A NO 20034660 A NO20034660 A NO 20034660A NO 20034660 D0 NO20034660 D0 NO 20034660D0
Authority
NO
Norway
Prior art keywords
spiropyrazolforbindelser
whereinz
compound
formula
disclosed
Prior art date
Application number
NO20034660A
Other languages
English (en)
Other versions
NO20034660L (no
Inventor
R Richard Goehring
Donald J Kyle
Gary Lee
Parviz Gharagozloo
Sam F Victory
Original Assignee
Euro Celtique Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euro Celtique Sa filed Critical Euro Celtique Sa
Publication of NO20034660D0 publication Critical patent/NO20034660D0/no
Publication of NO20034660L publication Critical patent/NO20034660L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
NO20034660A 2001-04-18 2003-10-17 Spiropyrazolforbindelser, farmasoytiske preparater som omfatter en slik forbindelse, og anvendelse av forbindelsene for fremstilling av farmasoytiske preparater NO20034660L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28467501P 2001-04-18 2001-04-18
PCT/US2002/012376 WO2002085355A1 (en) 2001-04-18 2002-04-18 Spiropyrazole compounds

Publications (2)

Publication Number Publication Date
NO20034660D0 true NO20034660D0 (no) 2003-10-17
NO20034660L NO20034660L (no) 2003-12-17

Family

ID=23091099

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20034660A NO20034660L (no) 2001-04-18 2003-10-17 Spiropyrazolforbindelser, farmasoytiske preparater som omfatter en slik forbindelse, og anvendelse av forbindelsene for fremstilling av farmasoytiske preparater

Country Status (28)

Country Link
US (2) US6635653B2 (no)
EP (1) EP1385515B1 (no)
JP (1) JP4342181B2 (no)
KR (1) KR100628292B1 (no)
CN (1) CN1516584A (no)
AT (1) ATE403429T1 (no)
AU (1) AU2002311833B2 (no)
BR (1) BR0209127A (no)
CA (1) CA2444634C (no)
CY (1) CY1108454T1 (no)
CZ (1) CZ20032849A3 (no)
DE (1) DE60228071D1 (no)
DK (1) DK1385515T3 (no)
ES (1) ES2312584T3 (no)
HK (1) HK1062885A1 (no)
HU (1) HUP0401333A3 (no)
IL (2) IL158485A0 (no)
MX (1) MXPA03009604A (no)
NO (1) NO20034660L (no)
NZ (1) NZ528978A (no)
PL (1) PL367263A1 (no)
PT (1) PT1385515E (no)
RU (1) RU2299883C2 (no)
SI (1) SI1385515T1 (no)
UA (1) UA74439C2 (no)
WO (1) WO2002085355A1 (no)
YU (1) YU82403A (no)
ZA (1) ZA200308103B (no)

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WO2004034983A2 (en) * 2002-10-17 2004-04-29 Euro-Celtique, S.A. Preparation of triazospiro compounds
US20040242583A1 (en) * 2003-01-20 2004-12-02 Aventis Pharma Deutschland Gmbh Pyrimido[5,4-e][1,2,4]triazine-5,7-diones, processes for preparing them and their use
WO2004103305A2 (en) * 2003-05-16 2004-12-02 Euroceltique S.A. Spiropyrazole compound
WO2005011665A1 (en) * 2003-07-22 2005-02-10 Arakis Ltd. The use of proglumide for the treatment of emesis
US20110008327A1 (en) 2004-03-29 2011-01-13 Cheng Jin Q Compositions including triciribine and epidermal growth factor receptor inhibitor compounds or salts thereof and methods of use thereof
US20100009929A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and bortezomib and derivatives thereof and methods of use thereof
US20100028339A1 (en) * 2004-03-29 2010-02-04 Cheng Jin Q Compositions including triciribine and trastuzumab and methods of use thereof
MXPA06011219A (es) 2004-03-29 2007-05-08 Univ South Florida Tratamiento efectivo de tumores y cancer con triciribina y compuestos relacionados.
US20100009928A1 (en) 2004-03-29 2010-01-14 Cheng Jin Q Compositions including triciribine and taxanes and methods of use thereof
US20100173864A1 (en) 2004-03-29 2010-07-08 Cheng Jin Q Compositions including triciribine and one or more platinum compounds and methods of use thereof
ES2350647T3 (es) 2005-03-08 2011-01-25 Janssen Pharmaceutica Nv Derivados de diaza-espiro-[4.4]-nonano como antagonistas de neuroquininas (nk1).
CN1870631B (zh) * 2005-11-11 2010-04-14 华为技术有限公司 媒体网关的门控方法
US20080051380A1 (en) 2006-08-25 2008-02-28 Auerbach Alan H Methods and compositions for treating cancer
AU2007325355A1 (en) 2006-11-28 2008-06-05 Janssen Pharmaceutica N.V. Salts of 3-(3-amino-2-(R)-hydroxy-propyl)-1-(4-fluoro-phenyl)-8-(8-methyl-naphthalen-1-ylmethyl) -1,3,8-triaza-spiro[4.5]decan-4-one
CN101595100B (zh) 2007-01-16 2014-06-11 普渡制药公司 作为orl-1配体的杂环取代的哌啶
US8741916B2 (en) 2007-04-09 2014-06-03 Janssen Pharmaceutica Nv 1,3,8-trisubstituted-1,3,8-triaza-spiro[4.5]decan-4-one derivatives as ligands of the ORL-1 receptor
EP3564240B1 (en) * 2007-08-31 2022-04-06 Purdue Pharma L.P. Piperidine intermediates
AU2009275218C1 (en) 2008-07-21 2015-02-05 Purdue Pharma L.P. Substituted-Quinoxaline-Type Bridged-Piperidine Compounds and the uses thereof
UA107943C2 (en) * 2009-11-16 2015-03-10 Lilly Co Eli Compounds of spiropiperidines as antagonists of the orl-1 receptors
AU2011346749A1 (en) 2010-12-22 2013-05-02 Purdue Pharma L.P. Phosphorus-substituted quinoxaline-type piperidine compounds and uses thereof
ES2583146T3 (es) 2011-12-01 2016-09-19 Purdue Pharma L.P. Compuestos de piperidina de tipo quinoxalina sustituidos con azetidina y usos de éstos
US9085561B2 (en) 2012-07-30 2015-07-21 Purdue Pharma L.P. Cyclic urea- or lactam-substituted quinoxaline-type piperidines as ORL-1 modulators
WO2014102588A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Indole and indoline-type piperidine compounds and uses thereof
US10118927B2 (en) 2012-12-27 2018-11-06 Purdue Pharma L.P. Substituted piperidin-4-amino-type compounds and uses thereof
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
US9090618B2 (en) 2012-12-27 2015-07-28 Purdue Pharma L.P. Substituted benzimidazole-type piperidine compounds and uses thereof
WO2014102589A1 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Quinazolin-4(3h)-one-type piperidine compounds and uses thereof
CN111825681A (zh) * 2020-07-07 2020-10-27 扬州大学 一种合成(e)-亚苄基螺吡唑吡咯嗪酮类化合物的方法

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US4410528A (en) 1980-05-16 1983-10-18 Kyowa Hakko Kogyo Co., Ltd. Hypotensive piperidine derivatives
JPS58180481A (ja) 1982-04-15 1983-10-21 Kyowa Hakko Kogyo Co Ltd 新規なピペリジン誘導体
JPS60120872A (ja) 1983-12-01 1985-06-28 Kyowa Hakko Kogyo Co Ltd 新規なヘテロ環状化合物及び強心剤
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ID29137A (id) 1998-07-27 2001-08-02 Schering Corp Ligan-ligan afinitas tinggi untuk reseptor nosiseptin orl-1
US6262066B1 (en) 1998-07-27 2001-07-17 Schering Corporation High affinity ligands for nociceptin receptor ORL-1
MA26659A1 (fr) 1998-08-06 2004-12-20 Pfizer Dérivés de benzimidazole nouveaux, compositions pharmaceutiques les contenant et procédé pour leur préparation.
SE9904652D0 (sv) 1999-12-17 1999-12-17 Astra Pharma Prod Novel Compounds
CA2421493A1 (en) 2000-09-06 2002-03-14 Ortho-Mcneil Pharmaceutical, Inc. A method for treating allergies using substituted pyrazoles
HUP0401333A3 (en) * 2001-04-18 2004-11-29 Euro Celtique Sa Spiropyrazole compounds and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
WO2002085355A1 (en) 2002-10-31
NZ528978A (en) 2004-06-25
UA74439C2 (uk) 2005-12-15
DK1385515T3 (da) 2008-10-27
HUP0401333A3 (en) 2004-11-29
CA2444634C (en) 2011-06-07
CA2444634A1 (en) 2002-10-31
PT1385515E (pt) 2008-09-15
CZ20032849A3 (en) 2004-03-17
ES2312584T3 (es) 2009-03-01
AU2002311833B2 (en) 2005-04-28
MXPA03009604A (es) 2004-04-02
HUP0401333A2 (hu) 2004-10-28
RU2003133455A (ru) 2005-05-10
IL158485A0 (en) 2004-05-12
PL367263A1 (en) 2005-02-21
US20030027834A1 (en) 2003-02-06
KR20040008159A (ko) 2004-01-28
CY1108454T1 (el) 2014-04-09
IL158485A (en) 2009-09-01
EP1385515B1 (en) 2008-08-06
EP1385515A1 (en) 2004-02-04
US20040087641A1 (en) 2004-05-06
HK1062885A1 (en) 2004-12-03
RU2299883C2 (ru) 2007-05-27
NO20034660L (no) 2003-12-17
JP2004531531A (ja) 2004-10-14
DE60228071D1 (de) 2008-09-18
CN1516584A (zh) 2004-07-28
ATE403429T1 (de) 2008-08-15
KR100628292B1 (ko) 2006-09-27
BR0209127A (pt) 2006-03-21
YU82403A (sh) 2006-08-17
JP4342181B2 (ja) 2009-10-14
US6635653B2 (en) 2003-10-21
SI1385515T1 (sl) 2008-12-31
ZA200308103B (en) 2004-10-18
EP1385515A4 (en) 2004-06-30

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