MXPA02011913A - Triazolopirimidinas sustituidas como agentes anticancer. - Google Patents

Triazolopirimidinas sustituidas como agentes anticancer.

Info

Publication number
MXPA02011913A
MXPA02011913A MXPA02011913A MXPA02011913A MXPA02011913A MX PA02011913 A MXPA02011913 A MX PA02011913A MX PA02011913 A MXPA02011913 A MX PA02011913A MX PA02011913 A MXPA02011913 A MX PA02011913A MX PA02011913 A MXPA02011913 A MX PA02011913A
Authority
MX
Mexico
Prior art keywords
mammal
substituted
triazolopyrimidines
anticancer agents
inhibiting
Prior art date
Application number
MXPA02011913A
Other languages
English (en)
Inventor
Mark R Schmitt
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of MXPA02011913A publication Critical patent/MXPA02011913A/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

La invencion proporciona un metodo para tratar o inhibir el crecimiento de celulas tumorales cancerosas y enfermedades asociadas en un mamifero que necesita del mismo, el cual comprende administrar al mamifero una cantidad efectiva de un derivado de triazolopirimidina sustituida o una sal farmaceuticamente aceptable del mismo y ademas proporciona un metodo para tratar o inhibir el crecimiento de celulas tumorales cancerosas y enfermedades asociadas en un mamifero que necesita del mismo al interactuar con tubulina y microtubulos y al promover la polimerizacion de microtubulo el cual comprende administrar al mamifero, una cantidad efectiva de un derivado de triazolopirimidina sustituida o una sal farmaceuticamente aceptable del mismo.
MXPA02011913A 2000-06-30 2001-06-28 Triazolopirimidinas sustituidas como agentes anticancer. MXPA02011913A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21558500P 2000-06-30 2000-06-30
PCT/US2001/020672 WO2002002563A2 (en) 2000-06-30 2001-06-28 Substituted-triazolopyrimidines as anticancer agents

Publications (1)

Publication Number Publication Date
MXPA02011913A true MXPA02011913A (es) 2003-04-22

Family

ID=22803554

Family Applications (1)

Application Number Title Priority Date Filing Date
MXPA02011913A MXPA02011913A (es) 2000-06-30 2001-06-28 Triazolopirimidinas sustituidas como agentes anticancer.

Country Status (24)

Country Link
US (1) US7329663B2 (es)
EP (1) EP1307200A2 (es)
JP (1) JP2004502691A (es)
KR (1) KR20030013475A (es)
CN (1) CN1592624A (es)
AR (1) AR034553A1 (es)
AU (2) AU7306201A (es)
BG (1) BG107277A (es)
BR (1) BR0112038A (es)
CA (1) CA2413802A1 (es)
CZ (1) CZ20024150A3 (es)
EA (1) EA006483B1 (es)
GE (1) GEP20053688B (es)
HK (1) HK1052646A1 (es)
HU (1) HUP0300798A3 (es)
IL (1) IL152869A0 (es)
IN (1) IN2003KO00001A (es)
MX (1) MXPA02011913A (es)
NO (1) NO20026195L (es)
NZ (1) NZ523807A (es)
PL (1) PL360027A1 (es)
SK (1) SK18412002A3 (es)
WO (1) WO2002002563A2 (es)
ZA (1) ZA200300793B (es)

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UA80304C2 (en) * 2002-11-07 2007-09-10 Basf Ag Substituted 6-(2-halogenphenyl)triazolopyrimidines
AU2004226233A1 (en) * 2003-03-31 2004-10-14 Basf Aktiengesellschaft 7-alkenylamino-triazolopyrimidines, method for the production thereof and use thereof in controlling harmful fungi and substances containing said triazolopyrimidines
DE10325133A1 (de) * 2003-06-04 2004-12-23 Bayer Cropscience Ag Triazolopyrimidine
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DE10328173A1 (de) * 2003-06-24 2005-01-13 Bayer Cropscience Ag Triazolopyrimidine
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JP4606015B2 (ja) * 2003-11-25 2011-01-05 日本化薬株式会社 ［１，２，４］トリアゾロ［１，５−ａ］ピリミジン誘導体の新規医薬用途
MY179926A (en) 2003-12-08 2020-11-19 Wyeth Corp Process for the preparation of tubulin inhibitors
CN1894254A (zh) * 2003-12-17 2007-01-10 巴斯福股份公司 用于防治病原性真菌的6－(2,3,6－三氟苯基)***并嘧啶
JP2007514680A (ja) * 2003-12-17 2007-06-07 ビーエーエスエフ　アクチェンゲゼルシャフト ６−（２，４，６−トリハロフェニル）トリアゾロピリミジン、その製造方法、および植物病原性真菌類を防除するためのその使用、ならびにその物質を含有している農薬
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CN103889428A (zh) 2010-10-04 2014-06-25 肝炎与病毒研究所 乙型肝炎病毒抗原分泌的新型抑制剂
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CN103360398B (zh) * 2013-07-22 2015-03-25 山东大学 一种***并嘧啶类hiv-1逆转录酶抑制剂及其制备方法与应用
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KR101995533B1 (ko) * 2017-03-21 2019-07-02 한국화학연구원 [1,2,4]트리아졸로[4,3-a]퀴노잘린 아미노 페닐 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 BET 단백질 관련 질환의 예방 또는 치료용 약학적 조성물
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Also Published As

Publication number Publication date
IN2003KO00001A (es) 2005-12-02
GEP20053688B (en) 2005-12-12
AR034553A1 (es) 2004-03-03
KR20030013475A (ko) 2003-02-14
EA006483B1 (ru) 2005-12-29
EA200300091A1 (ru) 2003-08-28
AU7306201A (en) 2002-01-14
AU2001273062B2 (en) 2005-11-24
SK18412002A3 (sk) 2003-06-03
BG107277A (bg) 2004-01-30
JP2004502691A (ja) 2004-01-29
NO20026195L (no) 2003-02-27
ZA200300793B (en) 2004-07-20
CA2413802A1 (en) 2002-01-10
CN1592624A (zh) 2005-03-09
WO2002002563A2 (en) 2002-01-10
HK1052646A1 (zh) 2003-09-26
US20020068744A1 (en) 2002-06-06
NO20026195D0 (no) 2002-12-23
WO2002002563A3 (en) 2003-01-03
US7329663B2 (en) 2008-02-12
CZ20024150A3 (cs) 2003-09-17
PL360027A1 (en) 2004-09-06
BR0112038A (pt) 2003-04-01
HUP0300798A2 (hu) 2003-07-28
EP1307200A2 (en) 2003-05-07
HUP0300798A3 (en) 2006-02-28
IL152869A0 (en) 2003-06-24
NZ523807A (en) 2004-09-24

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