MX370489B - Anticuerpos contra madcam. - Google Patents

Anticuerpos contra madcam.

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Publication number
MX370489B
MX370489B MX2017011253A MX2017011253A MX370489B MX 370489 B MX370489 B MX 370489B MX 2017011253 A MX2017011253 A MX 2017011253A MX 2017011253 A MX2017011253 A MX 2017011253A MX 370489 B MX370489 B MX 370489B
Authority
MX
Mexico
Prior art keywords
antibodies
madcam
relates
human anti
nucleic acid
Prior art date
Application number
MX2017011253A
Other languages
English (en)
Inventor
L Green Larry
Kellermann Sirid-Aimee
Haak-Frendscho Mary
Pullen Nicholas
Molloy Elizabeth
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34794356&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX370489(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer filed Critical Pfizer
Publication of MX370489B publication Critical patent/MX370489B/es

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    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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Abstract

La presente invención se refiere a anticuerpos que incluyen anticuerpos humanos y porciones que ligan antígeno de los mismos que se ligan específicamente a MAdCAM, preferentemente a MAdCAM humano y que funcionan para inhibir MAdCAM. La invención también se refiere a anticuerpos antiMAdCAN humanos y porciones que ligan antígeno de los mismos. La invención también se refiere a anticuerpos que son quiméricos, biespecificos, derivatizados, anticuerpos de cadena simple o porciones de proteínas de fusión. La invención también se refiere a inmunoglobulinas aisladas de cadena pesada y liviana derivadas de anticuerpos anti-MAdCAM humanos y a moléculas de ácido nucleico que codifican tales inmunoglobulinas. la presente invención también se refiere a métodos para fabricar anticuerpos anti-MAdCAM humanos, a composiciones que comprenden estos anticuerpos y a métodos para usar los anticuerpos y composiciones para diagnóstico y tratamiento. La invención también provee métodos de terapia con genes que usan moléculas de ácido nucleico que codifican la cadena pesada y/o liviana de moléculas de inmunoglobulina que comprenden los anticuerpos anti-MAdCAM humanos. La invención también se refiere a plantas o animales transgénicos que comprenden moléculas de ácido nucleico de la invención.
MX2017011253A 2004-01-09 2005-01-07 Anticuerpos contra madcam. MX370489B (es)

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