DOP2005000002A - "anticuerpos contra madcam" - Google Patents

"anticuerpos contra madcam"

Info

Publication number
DOP2005000002A
DOP2005000002A DO2005000002A DO2005000002A DOP2005000002A DO P2005000002 A DOP2005000002 A DO P2005000002A DO 2005000002 A DO2005000002 A DO 2005000002A DO 2005000002 A DO2005000002 A DO 2005000002A DO P2005000002 A DOP2005000002 A DO P2005000002A
Authority
DO
Dominican Republic
Prior art keywords
antibodies
madcam
relates
human anti
nucleic acid
Prior art date
Application number
DO2005000002A
Other languages
English (en)
Inventor
Nicholas Pullen
Elizabeth Molloy
Sirid-Aimeee Kellermann
Larry L Green
Mary Haak-Frendscho
Original Assignee
Pfizer
Abgenix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34794356&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2005000002(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pfizer, Abgenix Inc filed Critical Pfizer
Publication of DOP2005000002A publication Critical patent/DOP2005000002A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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Abstract

La presente invencion se refiere a anticuerpos que incluyen anticuerpos humanos y porciones que ligan antigeno de los mismos que se ligan especificamente a MAdCAM, preferentemente a MAdCAM human y que funcionan para inhibir MAdCAM. La invencion tambien se refiere a anticuerpos anti-MAdCAM humans y porciones que ligan antigen de los nusmos. La invencion tambien se refiere a anticuerpos que son quimericos, biespecificos, derivatizados, anticuerpos de cadena simple o porciones de proteinas de fusion. La invencion tambien se refiere a inmunoglobulinas aisladas de cadena pesada y liviana derivadas de anticuerpos anti-MAdCAM humanos y a moleculas de acido nucleico que codifican tales inmunoglobulinas. La presente invencion tambien se refiere a metodos para fabricar anficuerpos anti-MAdCAM humanos, a composiciones que comprenden estos anticuerpos y a metodos para usar los anticuerpos y composiciones para diagnostico y tratamiento. La invencion tambien provee metodos de terapia con genes que usan moleculas de acido nucleico que codifican la cadena pesada y/o liviana de moleculas de inmunoglobulina que comprenden los anticuerpos anti-MAdCAM humanos. La invencion tambien se refrere a animales o plantas transgenicos que comprenden moleculas de acido nucleico de la invencion.
DO2005000002A 2004-01-09 2005-01-07 "anticuerpos contra madcam" DOP2005000002A (es)

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Application Number Priority Date Filing Date Title
US53549004P 2004-01-09 2004-01-09

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DOP2005000002A true DOP2005000002A (es) 2005-08-15

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DO2005000002A DOP2005000002A (es) 2004-01-09 2005-01-07 "anticuerpos contra madcam"

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US (6) US9328169B2 (es)
EP (2) EP2177537B1 (es)
JP (7) JP4315982B2 (es)
KR (2) KR20120048644A (es)
CN (1) CN1956738B (es)
AP (1) AP2006003689A0 (es)
AR (1) AR047372A1 (es)
AT (2) ATE522547T1 (es)
AU (1) AU2005204678B2 (es)
BR (2) BR122021007893B1 (es)
CA (1) CA2552523C (es)
CR (1) CR8485A (es)
DE (1) DE602005026779D1 (es)
DK (1) DK2177537T3 (es)
DO (1) DOP2005000002A (es)
EA (1) EA012872B1 (es)
EC (1) ECSP066741A (es)
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