MX2015009383A - Enfermedades relacionadas con aldehido toxico y tratamiento. - Google Patents
Enfermedades relacionadas con aldehido toxico y tratamiento.Info
- Publication number
- MX2015009383A MX2015009383A MX2015009383A MX2015009383A MX2015009383A MX 2015009383 A MX2015009383 A MX 2015009383A MX 2015009383 A MX2015009383 A MX 2015009383A MX 2015009383 A MX2015009383 A MX 2015009383A MX 2015009383 A MX2015009383 A MX 2015009383A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- related diseases
- toxic aldehyde
- aldehyde related
- toxic
- Prior art date
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/423—Oxazoles condensed with carbocyclic rings
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- A61K31/438—The ring being spiro-condensed with carbocyclic or heterocyclic ring systems
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- A61K31/47—Quinolines; Isoquinolines
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- C—CHEMISTRY; METALLURGY
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Abstract
La presente invención proporciona tratamiento, prevención, y/o reducción de un riesgo de una enfermedad, trastorno o condición en los cuales la toxicidad del aldehído está implicada en la patogénesis, incluyendo trastornos oculares, trastornos de la piel, condiciones asociadas con efectos dañinos de agentes vesicantes, y enfermedades autoinmune, inflamatoria, neurológica y cardiovascular con el uso de aminas primarias para atrapar aldehídos tóxicos, tales como MDA y HNE.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361755613P | 2013-01-23 | 2013-01-23 | |
US201361901796P | 2013-11-08 | 2013-11-08 | |
PCT/US2014/012762 WO2014116836A2 (en) | 2013-01-23 | 2014-01-23 | Toxic aldehyde related diseases and treatment |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2015009383A true MX2015009383A (es) | 2016-03-17 |
Family
ID=51228191
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2015009383A MX2015009383A (es) | 2013-01-23 | 2014-01-23 | Enfermedades relacionadas con aldehido toxico y tratamiento. |
MX2019012878A MX2019012878A (es) | 2013-01-23 | 2015-07-21 | Terapias para el tratamiento de enfermedades asociadas con la toxicidad del aldehido. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2019012878A MX2019012878A (es) | 2013-01-23 | 2015-07-21 | Terapias para el tratamiento de enfermedades asociadas con la toxicidad del aldehido. |
Country Status (13)
Country | Link |
---|---|
US (7) | US9687481B2 (es) |
EP (1) | EP2948149A4 (es) |
JP (4) | JP6514114B2 (es) |
KR (2) | KR102243169B1 (es) |
CN (3) | CN111135171B (es) |
AU (2) | AU2014209387B2 (es) |
CA (2) | CA2898631C (es) |
HK (1) | HK1217439A1 (es) |
IL (1) | IL239735B (es) |
MX (2) | MX2015009383A (es) |
RU (2) | RU2676694C9 (es) |
SG (1) | SG11201505587YA (es) |
WO (1) | WO2014116836A2 (es) |
Families Citing this family (27)
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US8940764B2 (en) | 2005-05-26 | 2015-01-27 | Aldexa Therapeutics, Inc. | Compositions and methods of treating retinal disease |
CA2782015C (en) | 2009-12-11 | 2020-08-25 | Neuron Systems, Inc. | Topical ophthalmic compositions and methods for the treatment of macular degeneration |
AU2013361314A1 (en) | 2012-12-20 | 2015-07-02 | Aldeyra Therapeutics, Inc. | Peri-carbinols |
CN111135171B (zh) | 2013-01-23 | 2023-09-08 | 奥尔德拉医疗公司 | 与毒性醛相关的疾病和治疗 |
AU2014209585A1 (en) | 2013-01-25 | 2015-07-23 | Aldeyra Therapeutics, Inc. | Novel traps in the treatment of macular degeneration |
EP3178810A4 (en) * | 2014-08-08 | 2018-07-04 | Kasuma Partners Inc. | Condensed heterocyclic compound |
BR112018003264A2 (pt) * | 2015-08-21 | 2018-09-25 | Aldeyra Therapeutics Inc | conjugados de aldeído e usos dos mesmos |
CN105085427B (zh) * | 2015-08-21 | 2018-06-05 | 中国科学院广州生物医药与健康研究院 | 一类苯并[d]异恶唑类化合物及其应用 |
WO2017035077A1 (en) * | 2015-08-21 | 2017-03-02 | Aldeyra Therapeutics, Inc. | Deuterated compounds and uses thereof |
CA3016759A1 (en) | 2016-02-28 | 2017-08-31 | Aldeyra Therapeutics, Inc. | Treatment of allergic eye conditions with cyclodextrins |
CA3022665A1 (en) * | 2016-05-09 | 2017-11-16 | Aldeyra Therapeutics, Inc. | Combination treatment of ocular inflammatory disorders and diseases |
CA3032521A1 (en) * | 2016-08-22 | 2018-03-01 | Aldeyra Therapeutics, Inc. | Aldehyde trapping compounds and uses thereof |
CA3054811A1 (en) * | 2017-03-16 | 2018-09-20 | Aldeyra Therapeutics, Inc. | Polymorphic compounds and uses thereof |
CN111356451A (zh) | 2017-10-10 | 2020-06-30 | 奥尔德拉医疗公司 | 炎性病症的治疗 |
TWI685338B (zh) | 2017-12-14 | 2020-02-21 | 柯瑞 伊里阿斯 J | 使用非可吸收性口服投予之化合物之包括第2型糖尿病、脂肪肝炎及相關病況之人類代謝症候群之預防及治療 |
WO2020028820A1 (en) | 2018-08-03 | 2020-02-06 | Aldeyra Therapeutics, Inc. | Topical compositions and methods of preparation and use |
CN112714762A (zh) | 2018-08-06 | 2021-04-27 | 奥尔德拉医疗公司 | 多晶型化合物及其用途 |
US11197821B2 (en) | 2018-09-25 | 2021-12-14 | Aldeyra Therapeutics, Inc. | Formulations for treatment of dry eye disease |
US11786518B2 (en) | 2019-03-26 | 2023-10-17 | Aldeyra Therapeutics, Inc. | Ophthalmic formulations and uses thereof |
CN113784954A (zh) | 2019-05-02 | 2021-12-10 | 奥尔德拉医疗公司 | 多晶型化合物和其用途 |
EP3785694A1 (en) * | 2019-08-30 | 2021-03-03 | Hangzhou Ocean Pearl Industrial Co., Ltd. | Eyeliner product and method thereof |
JP2023507900A (ja) * | 2019-12-30 | 2023-02-28 | 中国医▲薬▼研究▲開▼▲発▼中心有限公司 | 三環式化合物、及びその調製方法、及びその医薬的使用 |
EP4135697A1 (en) * | 2020-04-13 | 2023-02-22 | Aldeyra Therapeutics, Inc. | Quinoline compounds for treating lung, liver, and kidney diseases, disorders, or conditions |
JP2022053772A (ja) * | 2020-09-25 | 2022-04-06 | Jswアフティ株式会社 | ターゲットおよび成膜装置 |
JP2024503325A (ja) * | 2020-12-29 | 2024-01-25 | 中国医▲薬▼研究▲開▼▲発▼中心有限公司 | 三環式化合物、及びその調製方法、及びその医薬的使用 |
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