MX2015009383A - Enfermedades relacionadas con aldehido toxico y tratamiento. - Google Patents

Enfermedades relacionadas con aldehido toxico y tratamiento.

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Publication number
MX2015009383A
MX2015009383A MX2015009383A MX2015009383A MX2015009383A MX 2015009383 A MX2015009383 A MX 2015009383A MX 2015009383 A MX2015009383 A MX 2015009383A MX 2015009383 A MX2015009383 A MX 2015009383A MX 2015009383 A MX2015009383 A MX 2015009383A
Authority
MX
Mexico
Prior art keywords
treatment
related diseases
toxic aldehyde
aldehyde related
toxic
Prior art date
Application number
MX2015009383A
Other languages
English (en)
Inventor
William A Kinney
Todd Brady
Scott Young
Kenneth J Mandell
Original Assignee
Aldeyra Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aldeyra Therapeutics Inc filed Critical Aldeyra Therapeutics Inc
Publication of MX2015009383A publication Critical patent/MX2015009383A/es

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    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00Use of organic ingredients
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    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08KUse of inorganic or non-macromolecular organic substances as compounding ingredients
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    • C08K5/08Quinones
    • CCHEMISTRY; METALLURGY
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    • C08K5/18Amines; Quaternary ammonium compounds with aromatically bound amino groups

Abstract

La presente invención proporciona tratamiento, prevención, y/o reducción de un riesgo de una enfermedad, trastorno o condición en los cuales la toxicidad del aldehído está implicada en la patogénesis, incluyendo trastornos oculares, trastornos de la piel, condiciones asociadas con efectos dañinos de agentes vesicantes, y enfermedades autoinmune, inflamatoria, neurológica y cardiovascular con el uso de aminas primarias para atrapar aldehídos tóxicos, tales como MDA y HNE.
MX2015009383A 2013-01-23 2014-01-23 Enfermedades relacionadas con aldehido toxico y tratamiento. MX2015009383A (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361755613P 2013-01-23 2013-01-23
US201361901796P 2013-11-08 2013-11-08
PCT/US2014/012762 WO2014116836A2 (en) 2013-01-23 2014-01-23 Toxic aldehyde related diseases and treatment

Publications (1)

Publication Number Publication Date
MX2015009383A true MX2015009383A (es) 2016-03-17

Family

ID=51228191

Family Applications (2)

Application Number Title Priority Date Filing Date
MX2015009383A MX2015009383A (es) 2013-01-23 2014-01-23 Enfermedades relacionadas con aldehido toxico y tratamiento.
MX2019012878A MX2019012878A (es) 2013-01-23 2015-07-21 Terapias para el tratamiento de enfermedades asociadas con la toxicidad del aldehido.

Family Applications After (1)

Application Number Title Priority Date Filing Date
MX2019012878A MX2019012878A (es) 2013-01-23 2015-07-21 Terapias para el tratamiento de enfermedades asociadas con la toxicidad del aldehido.

Country Status (13)

Country Link
US (7) US9687481B2 (es)
EP (1) EP2948149A4 (es)
JP (4) JP6514114B2 (es)
KR (2) KR102243169B1 (es)
CN (3) CN111135171B (es)
AU (2) AU2014209387B2 (es)
CA (2) CA2898631C (es)
HK (1) HK1217439A1 (es)
IL (1) IL239735B (es)
MX (2) MX2015009383A (es)
RU (2) RU2676694C9 (es)
SG (1) SG11201505587YA (es)
WO (1) WO2014116836A2 (es)

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CN112714762A (zh) 2018-08-06 2021-04-27 奥尔德拉医疗公司 多晶型化合物及其用途
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CN113784954A (zh) 2019-05-02 2021-12-10 奥尔德拉医疗公司 多晶型化合物和其用途
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JP2023507900A (ja) * 2019-12-30 2023-02-28 中国医▲薬▼研究▲開▼▲発▼中心有限公司 三環式化合物、及びその調製方法、及びその医薬的使用
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JP2024503325A (ja) * 2020-12-29 2024-01-25 中国医▲薬▼研究▲開▼▲発▼中心有限公司 三環式化合物、及びその調製方法、及びその医薬的使用
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