JPH05507475A - ロイコトリエン関連疾患治療用安息香酸誘導体 - Google Patents
ロイコトリエン関連疾患治療用安息香酸誘導体Info
- Publication number
- JPH05507475A JPH05507475A JP91509448A JP50944891A JPH05507475A JP H05507475 A JPH05507475 A JP H05507475A JP 91509448 A JP91509448 A JP 91509448A JP 50944891 A JP50944891 A JP 50944891A JP H05507475 A JPH05507475 A JP H05507475A
- Authority
- JP
- Japan
- Prior art keywords
- aliphatic group
- compound according
- group
- aryl
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/64—One oxygen atom attached in position 2 or 6
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53438890A | 1990-06-07 | 1990-06-07 | |
| US534.388 | 1990-06-07 | ||
| PCT/US1991/003399 WO1991018880A1 (en) | 1990-06-07 | 1991-05-15 | Benzoic acid derivatives for treating leukotriene-related diseases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH05507475A true JPH05507475A (ja) | 1993-10-28 |
Family
ID=24129833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP91509448A Pending JPH05507475A (ja) | 1990-06-07 | 1991-05-15 | ロイコトリエン関連疾患治療用安息香酸誘導体 |
Country Status (16)
| Country | Link |
|---|---|
| EP (1) | EP0532550A1 (fi) |
| JP (1) | JPH05507475A (fi) |
| KR (1) | KR930700445A (fi) |
| CN (1) | CN1058016A (fi) |
| AU (1) | AU7901791A (fi) |
| CA (1) | CA2083958A1 (fi) |
| FI (1) | FI925544A (fi) |
| HU (1) | HUT64748A (fi) |
| IE (2) | IE911913A1 (fi) |
| IL (1) | IL98388A0 (fi) |
| MA (1) | MA22196A1 (fi) |
| MX (1) | MX26142A (fi) |
| PL (1) | PL290586A1 (fi) |
| PT (1) | PT97912A (fi) |
| WO (1) | WO1991018880A1 (fi) |
| ZA (1) | ZA914323B (fi) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU4226493A (en) * | 1992-05-01 | 1993-11-29 | Smithkline Beecham Corporation | Leukotriene antagonists |
| WO1995015950A1 (en) * | 1993-12-08 | 1995-06-15 | Smithkline Beecham Corporation | Compounds |
| IL106156A0 (en) * | 1992-06-30 | 1993-10-20 | Smithkline Beecham Corp | Pyridinyl compounds |
| WO1994014442A1 (en) * | 1992-12-23 | 1994-07-07 | Smithkline Beecham Corporation | Substituted pyridyl compounds useful as leukotriene antagonists |
| BR9507459A (pt) * | 1994-04-13 | 1997-11-11 | Hoffmann La Roche | Antagonistas á base de piridino-leucotrieno b4 substituído |
| US7297357B2 (en) * | 2001-03-27 | 2007-11-20 | Meiji Seika Kaisha, Ltd. | Process for producing puffed snack and production apparatus therefor |
| ES2622522T3 (es) | 2003-08-26 | 2017-07-06 | The Regents Of The University Of Colorado, A Body Corporate | Inhibidores de la actividad proteasa de serina y su uso en métodos y composiciones para el tratamiento de infecciones bacterianas |
| US8093253B2 (en) | 2008-03-06 | 2012-01-10 | Hoffmann-La Roche Inc. | Leukotriene B4 inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4563446A (en) * | 1983-07-27 | 1986-01-07 | Takeda Chemical Industries, Ltd. | Thromboxane synthetase inhibiting 3-(1-alkenyl) pyridines |
| GB8505285D0 (en) * | 1985-03-01 | 1985-04-03 | Beecham Group Plc | Compounds |
-
1991
- 1991-05-15 HU HU9203866A patent/HUT64748A/hu unknown
- 1991-05-15 AU AU79017/91A patent/AU7901791A/en not_active Abandoned
- 1991-05-15 CA CA002083958A patent/CA2083958A1/en not_active Abandoned
- 1991-05-15 JP JP91509448A patent/JPH05507475A/ja active Pending
- 1991-05-15 EP EP91909997A patent/EP0532550A1/en not_active Withdrawn
- 1991-05-15 KR KR1019920703090A patent/KR930700445A/ko not_active Application Discontinuation
- 1991-05-15 WO PCT/US1991/003399 patent/WO1991018880A1/en not_active Application Discontinuation
- 1991-06-03 MA MA22442A patent/MA22196A1/fr unknown
- 1991-06-05 IE IE191391A patent/IE911913A1/en unknown
- 1991-06-05 IL IL98388A patent/IL98388A0/xx unknown
- 1991-06-05 IE IE191291A patent/IE911912A1/en unknown
- 1991-06-06 MX MX2614291A patent/MX26142A/es unknown
- 1991-06-06 ZA ZA914323A patent/ZA914323B/xx unknown
- 1991-06-07 PL PL29058691A patent/PL290586A1/xx unknown
- 1991-06-07 PT PT97912A patent/PT97912A/pt not_active Application Discontinuation
- 1991-06-07 CN CN91104564A patent/CN1058016A/zh active Pending
-
1992
- 1992-12-07 FI FI925544A patent/FI925544A/fi not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0532550A1 (en) | 1993-03-24 |
| FI925544A0 (fi) | 1992-12-07 |
| HUT64748A (en) | 1994-02-28 |
| CA2083958A1 (en) | 1991-12-08 |
| AU7901791A (en) | 1991-12-31 |
| MA22196A1 (fr) | 1992-04-01 |
| ZA914323B (en) | 1992-06-24 |
| IE911912A1 (en) | 1991-12-18 |
| IE911913A1 (en) | 1991-12-18 |
| HU9203866D0 (en) | 1993-03-29 |
| FI925544A (fi) | 1992-12-07 |
| MX26142A (es) | 1994-02-28 |
| WO1991018880A1 (en) | 1991-12-12 |
| CN1058016A (zh) | 1992-01-22 |
| IL98388A0 (en) | 1992-07-15 |
| PT97912A (pt) | 1992-03-31 |
| PL290586A1 (en) | 1992-04-06 |
| KR930700445A (ko) | 1993-03-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE602004006631T2 (de) | Matrix metalloprotease inhibitoren | |
| DE60309598T2 (de) | Als histamin-h3-antagonisten geeignete indolderivate | |
| DE69732966T2 (de) | Substituierte indazolderivate und ihre verwendung als inhibitoren des phosphodiesterase (pde) des typs iv und der produktion des tumor nekrosis faktors (tnf) | |
| DE69926542T2 (de) | Aminopyrazolderivate | |
| US4038396A (en) | Anti-inflammatory oxazole[4,5-b]pyridines | |
| DE60201859T2 (de) | Pharmazeutische Verwendung von N-Carbamoylazol-Derivate | |
| JP2007524682A (ja) | 代謝調節型グルタミン酸受容体−５の調節物質としてのビピリジルアミド | |
| JPH05507713A (ja) | 置換ベンズイミダゾール、その製造方法およびその薬学的使用 | |
| JPH11505236A (ja) | フェニルジヒドロベンゾフラン | |
| DE3522579C2 (de) | Neue 1,4-Dihydropyridin-Derivate und Salze derselben, Verfahren zur Herstellung derselben und pharmazeutische Mittel mit einem Gehalt derselben | |
| JPH05507475A (ja) | ロイコトリエン関連疾患治療用安息香酸誘導体 | |
| JPH01301661A (ja) | 新規ピリジル誘導体 | |
| ES2408961T3 (es) | Derivados de amidas del ácido 3-trifluorometil-pirazin-2-carboxílico como agentes para aumentar el colesterol HDL. | |
| DE60024648T2 (de) | Carbonsäuren und acylsulfonamide, diese verbindungen enthaltende zubereitungen und behandlungsmethoden | |
| JPH06510786A (ja) | ロイコトリエン関連疾患治療用ピリジン化合物 | |
| JPH05507492A (ja) | 安息香酸誘導体 | |
| JPS60149576A (ja) | 坑炎症剤として有用な置換ヒドロキシ−２，３−ジヒドロベンゾフランおよびその類似体 | |
| ES2391371T3 (es) | Derivados de la 2-trifluorometilnicotinamida como agentes para aumentar el HDL-colesterol | |
| JPH03163074A (ja) | フラン誘導体 | |
| JPH05507701A (ja) | ロイコトリエン関連疾患治療用フタルアミド酸およびその異性体 | |
| FR2911605A1 (fr) | Derives de pyrrolopyridine-2-carbowamides, leur preparation et leur application en therapeutique | |
| WO1998058930A1 (fr) | Composes de triazolo-1,4-diazepine et composition medicinale les contenant | |
| US4783473A (en) | Geminally substituted cyclic ether carboxylic acids, derivatives thereof, compositions containing same and method of use | |
| JPH05507698A (ja) | ロイコトリエン関連疾患治療用アミド結合ピリジル―安息香酸誘導体 | |
| US4131677A (en) | Anti-inflammatory oxazolo [5,4-b]pyridines |