JP2022517951A - 骨髄異形成症候群を処置するためのａｌｋ５阻害剤 - Google Patents

骨髄異形成症候群を処置するためのａｌｋ５阻害剤 Download PDF

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Publication number: JP2022517951A
Authority: JP; Japan
Prior art keywords: compound; subject; mds; hemoglobin; predetermined amount
Prior art date: 2019-01-10
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

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JP2021539926A

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English (en)

Japanese (ja)

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JPWO2020146819A5 (ko

Inventor

デイビッドジェイ．ベアス，

スティーブンエル．ワーナー，

Original Assignee

スミトモダイニッポンファーマオンコロジー，インコーポレイテッド

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2019-01-10

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2020-01-10

Publication date

2022-03-11

2020-01-10 Application filed by スミトモダイニッポンファーマオンコロジー，インコーポレイテッド filed Critical スミトモダイニッポンファーマオンコロジー，インコーポレイテッド

2022-03-11 Publication of JP2022517951A publication Critical patent/JP2022517951A/ja

2023-01-20 Publication of JPWO2020146819A5 publication Critical patent/JPWO2020146819A5/ja

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- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
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- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
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JP2021539926A 2019-01-10 2020-01-10 骨髄異形成症候群を処置するためのａｌｋ５阻害剤 Pending JP2022517951A (ja)

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US201962790961P	2019-01-10	2019-01-10
US62/790,961		2019-01-10
PCT/US2020/013214 WO2020146819A1 (en)	2019-01-10	2020-01-10	Alk5 inhibitors for treating myelodysplastic syndrome

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EP (1)	EP3908575A4 (ko)
JP (1)	JP2022517951A (ko)
KR (1)	KR20210113314A (ko)
CN (1)	CN113272281A (ko)
AU (1)	AU2020207391A1 (ko)
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EP3908575A4 (en)	2022-09-14
CA3124714A1 (en)	2020-07-16
US20240075033A1 (en)	2024-03-07
CN113272281A (zh)	2021-08-17
WO2020146819A1 (en)	2020-07-16
US20200323851A1 (en)	2020-10-15
EP3908575A1 (en)	2021-11-17
AU2020207391A1 (en)	2021-06-24
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