IN2012DN02751A - - Google Patents

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Publication number
IN2012DN02751A
IN2012DN02751A IN2751DEN2012A IN2012DN02751A IN 2012DN02751 A IN2012DN02751 A IN 2012DN02751A IN 2751DEN2012 A IN2751DEN2012 A IN 2751DEN2012A IN 2012DN02751 A IN2012DN02751 A IN 2012DN02751A
Authority
IN
India
Prior art keywords
glucopyranosyi
preparing
processes
general formula
formula iii
Prior art date
Application number
Other languages
English (en)
Inventor
Weber Dirk
Fiedler Tobias
Filser Christian
Hamm Rainer
Orlich Simone
Post Matthias
Renner Svenja
Wang Xiao-Jun
Wirth Thomas
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IN2012DN02751A publication Critical patent/IN2012DN02751A/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C07H1/06—Separation; Purification
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H7/00—Compounds containing non-saccharide radicals linked to saccharide radicals by a carbon-to-carbon bond
    • C07H7/04—Carbocyclic radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Packaging Of Annular Or Rod-Shaped Articles, Wearing Apparel, Cassettes, Or The Like (AREA)
  • Wrapping Of Specific Fragile Articles (AREA)
IN2751DEN2012 2009-09-30 2010-09-24 IN2012DN02751A (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US24714409P 2009-09-30 2009-09-30
PCT/EP2010/064120 WO2011039108A2 (en) 2009-09-30 2010-09-24 Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives

Publications (1)

Publication Number Publication Date
IN2012DN02751A true IN2012DN02751A (uk) 2015-09-18

Family

ID=43736212

Family Applications (1)

Application Number Title Priority Date Filing Date
IN2751DEN2012 IN2012DN02751A (uk) 2009-09-30 2010-09-24

Country Status (24)

Country Link
US (2) US9024010B2 (uk)
EP (1) EP2486029B1 (uk)
JP (1) JP5758900B2 (uk)
KR (1) KR101813025B1 (uk)
CN (1) CN102574829B (uk)
AR (1) AR078193A1 (uk)
AU (1) AU2010303124B2 (uk)
BR (1) BR112012007085B8 (uk)
CA (1) CA2775962C (uk)
CL (1) CL2012000581A1 (uk)
DK (1) DK2486029T3 (uk)
EA (1) EA022032B1 (uk)
ES (1) ES2546762T3 (uk)
HR (1) HRP20150945T1 (uk)
HU (1) HUE026133T2 (uk)
IL (1) IL218101A0 (uk)
IN (1) IN2012DN02751A (uk)
MX (1) MX2012003048A (uk)
NZ (1) NZ598366A (uk)
PL (1) PL2486029T3 (uk)
PT (1) PT2486029E (uk)
SI (1) SI2486029T1 (uk)
TW (1) TWI465458B (uk)
WO (1) WO2011039108A2 (uk)

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* Cited by examiner, † Cited by third party
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US10610489B2 (en) 2009-10-02 2020-04-07 Boehringer Ingelheim International Gmbh Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
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US20130035298A1 (en) 2011-07-08 2013-02-07 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
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US9193751B2 (en) 2012-04-10 2015-11-24 Theracos, Inc. Process for the preparation of benzylbenzene SGLT2 inhibitors
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US20140303098A1 (en) 2013-04-05 2014-10-09 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
US11813275B2 (en) 2013-04-05 2023-11-14 Boehringer Ingelheim International Gmbh Pharmaceutical composition, methods for treating and uses thereof
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CN108794548B (zh) * 2017-04-28 2023-06-16 正大天晴药业集团股份有限公司 制备恩格列净及其中间体的方法
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CN110872216A (zh) * 2019-12-06 2020-03-10 南京恒道医药科技有限公司 一种反应分离耦合生产(2-氯-5-碘苯基)-4-氟苯甲基酮的方法及装置
CN110903315A (zh) * 2019-12-16 2020-03-24 上海网义化工有限公司 一种D-葡萄糖酸-γ-内酯中间体的制备方法
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CN111410639B (zh) * 2020-04-14 2021-02-26 天津法莫西医药科技有限公司 一种恩格列净中间体杂质的制备方法
CN112194655B (zh) * 2020-10-15 2022-08-09 通化东宝药业股份有限公司 一种恩格列净的制备方法
KR20220068805A (ko) 2020-11-19 2022-05-26 한미약품 주식회사 신규한 글루코스 유도체
CN113480497B (zh) * 2021-07-27 2023-02-28 山东铂源药业股份有限公司 一种恩格列净关键中间体的合成方法
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CN114716425B (zh) * 2022-04-11 2023-09-01 沧州那瑞化学科技有限公司 芳香杂环取代亚甲基的化合物的合成方法
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