HUP0004701A2 - Új dezloratadin sók, az ezeket tartalmazó gyógyászati készítmények és eljárás azok előállítására - Google Patents

Új dezloratadin sók, az ezeket tartalmazó gyógyászati készítmények és eljárás azok előállítására

Info

Publication number
HUP0004701A2
HUP0004701A2 HU0004701A HUP0004701A HUP0004701A2 HU P0004701 A2 HUP0004701 A2 HU P0004701A2 HU 0004701 A HU0004701 A HU 0004701A HU P0004701 A HUP0004701 A HU P0004701A HU P0004701 A2 HUP0004701 A2 HU P0004701A2
Authority
HU
Hungary
Prior art keywords
preparation
desloratadine
pharmaceutical compositions
compositions containing
new salts
Prior art date
Application number
HU0004701A
Other languages
English (en)
Inventor
János Fischer
Tamás Fodor
Sándor Lévai
Endréné Petényi
Ferenc Trischler
Original Assignee
Richter Gedeon Vegyészeti Gyár Rt.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyészeti Gyár Rt. filed Critical Richter Gedeon Vegyészeti Gyár Rt.
Priority to HU0004701A priority Critical patent/HU226998B1/hu
Publication of HU0004701D0 publication Critical patent/HU0004701D0/hu
Priority to CZ2003-1321A priority patent/CZ304694B6/cs
Priority to CNB018193382A priority patent/CN1199968C/zh
Priority to AU2002218422A priority patent/AU2002218422A1/en
Priority to UA2003065756A priority patent/UA74858C2/uk
Priority to DE60116902T priority patent/DE60116902T2/de
Priority to US10/432,387 priority patent/US7196195B2/en
Priority to PL362126A priority patent/PL206973B1/pl
Priority to ES01997485T priority patent/ES2257467T3/es
Priority to DK01997485T priority patent/DK1347965T3/da
Priority to CA002425422A priority patent/CA2425422C/en
Priority to AT01997485T priority patent/ATE316525T1/de
Priority to PCT/HU2001/000111 priority patent/WO2002042290A1/en
Priority to RU2003118425/04A priority patent/RU2285001C2/ru
Priority to SK566-2003A priority patent/SK285715B6/sk
Priority to EP01997485A priority patent/EP1347965B1/en
Priority to SI200130510T priority patent/SI1347965T1/sl
Priority to JP2002544424A priority patent/JP4427249B2/ja
Publication of HUP0004701A2 publication Critical patent/HUP0004701A2/hu
Priority to NO20032314A priority patent/NO325155B1/no
Priority to CY20061100435T priority patent/CY1105595T1/el
Publication of HU226998B1 publication Critical patent/HU226998B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A találmány tárgya (I) vagy (II) képletű savaddíciós sók - ahol aképletben X jelentése savmaradék és n jelentése 1 vagy 2. A találmánya fenti vegyületek előállítására is vonatkozik. A találmány tárgyatovábbá allergiaellenes gyógyászati készítmény, amely 0,1-99,9 tömeg%(I) vagy (II) képletű hatóanyagot és 0,1-99,9 tömeg%gyógyszerkészítésben szokásos segéd- vagy formulálásra alkalmasanyagot tartalmaz. Ó
HU0004701A 2000-11-23 2000-11-23 Desloratadine hemisulphate, process for the preparation thereof and pharmaceutical compositions containing the same HU226998B1 (en)

Priority Applications (20)

Application Number Priority Date Filing Date Title
HU0004701A HU226998B1 (en) 2000-11-23 2000-11-23 Desloratadine hemisulphate, process for the preparation thereof and pharmaceutical compositions containing the same
JP2002544424A JP4427249B2 (ja) 2000-11-23 2001-11-14 新規デスロラタジン塩、その合成方法および医薬組成物
CA002425422A CA2425422C (en) 2000-11-23 2001-11-14 Stable desloratadine salts, process for their synthesis, and pharmaceutical compositions thereof
PCT/HU2001/000111 WO2002042290A1 (en) 2000-11-23 2001-11-14 New desloratadine salts, process for their synthesis and pharmaceutical compositions thereof
AU2002218422A AU2002218422A1 (en) 2000-11-23 2001-11-14 New desloratadine salts, process for their synthesis and pharmaceutical compositions thereof
UA2003065756A UA74858C2 (en) 2000-11-23 2001-11-14 Desloratadine half-sulphate, a method for producing desloratadine salts and a pharmaceutical composition containing it
DE60116902T DE60116902T2 (de) 2000-11-23 2001-11-14 Neue desloratadinsalze, verfahren zu deren synthese und diese enthaltende pharmazeutische zusammensetzungen
US10/432,387 US7196195B2 (en) 2000-11-23 2001-11-14 Desloratadine salts, process for their synthesis and pharmaceutical compositions thereof
PL362126A PL206973B1 (pl) 2000-11-23 2001-11-14 Hemisiarczan desloratadyny, sposób wytwarzania soli desloratadyny i przeciwalergiczny środek farmaceutyczny
ES01997485T ES2257467T3 (es) 2000-11-23 2001-11-14 Nuevas sales de desloratadina, proceso para su sintesis y composiciones farmaceuticas de las mismas.
DK01997485T DK1347965T3 (da) 2000-11-23 2001-11-14 Hidtil ukendte desloratidinsalte, fremgangsmåde til syntese deraf samt farmaceutiske præparater deraf
CZ2003-1321A CZ304694B6 (cs) 2000-11-23 2001-11-14 Soli desloratadinu, způsob jejich přípravy a farmaceutické přípravky je obsahující
AT01997485T ATE316525T1 (de) 2000-11-23 2001-11-14 Neue desloratadinsalze, verfahren zu deren synthese und diese enthaltende pharmazeutische zusammensetzungen
CNB018193382A CN1199968C (zh) 2000-11-23 2001-11-14 新的地洛他定盐、其合成方法及其药物组合物
RU2003118425/04A RU2285001C2 (ru) 2000-11-23 2001-11-14 Деслоратадин-полусульфат, способ его получения, фармацевтическая композиция, его содержащая, и способ получения исходного продукта
SK566-2003A SK285715B6 (sk) 2000-11-23 2001-11-14 Soli desloratadínu, spôsob ich prípravy a farmaceutické prípravky s ich obsahom
EP01997485A EP1347965B1 (en) 2000-11-23 2001-11-14 New desloratadine salts, process for their synthesis and pharmaceutical compositions thereof
SI200130510T SI1347965T1 (sl) 2000-11-23 2001-11-14 Nove soli desloratadina, postopek za njihovo sintezo in njihovi farmacevtski sestavki
NO20032314A NO325155B1 (no) 2000-11-23 2003-05-22 Nye desloratadinhemisulfat, fremgangsmate for deres syntese og farmasoytiske preparater derav
CY20061100435T CY1105595T1 (el) 2000-11-23 2006-03-29 Νεα αλατα δεσλοραταδινης, μεθοδος συνθεσης τους και φαρμακευτικα σκευασματα αυτων

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU0004701A HU226998B1 (en) 2000-11-23 2000-11-23 Desloratadine hemisulphate, process for the preparation thereof and pharmaceutical compositions containing the same

Publications (3)

Publication Number Publication Date
HU0004701D0 HU0004701D0 (hu) 2001-02-28
HUP0004701A2 true HUP0004701A2 (hu) 2002-11-28
HU226998B1 HU226998B1 (en) 2010-04-28

Family

ID=89978790

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0004701A HU226998B1 (en) 2000-11-23 2000-11-23 Desloratadine hemisulphate, process for the preparation thereof and pharmaceutical compositions containing the same

Country Status (19)

Country Link
US (1) US7196195B2 (hu)
EP (1) EP1347965B1 (hu)
JP (1) JP4427249B2 (hu)
CN (1) CN1199968C (hu)
AT (1) ATE316525T1 (hu)
AU (1) AU2002218422A1 (hu)
CA (1) CA2425422C (hu)
CY (1) CY1105595T1 (hu)
CZ (1) CZ304694B6 (hu)
DE (1) DE60116902T2 (hu)
DK (1) DK1347965T3 (hu)
ES (1) ES2257467T3 (hu)
HU (1) HU226998B1 (hu)
NO (1) NO325155B1 (hu)
PL (1) PL206973B1 (hu)
RU (1) RU2285001C2 (hu)
SK (1) SK285715B6 (hu)
UA (1) UA74858C2 (hu)
WO (1) WO2002042290A1 (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003262141A1 (en) * 2002-04-15 2003-10-27 Sun Pharmaceutical Industries Limited Preperation of desloratatine
AU2003251974C1 (en) * 2002-08-05 2006-09-14 Sandoz Ag Novel salt and polymorphs of desloratadine hemifumarate
JP4501015B2 (ja) 2004-03-17 2010-07-14 味の素株式会社 アミノピリミジン化合物の製造方法
WO2006003479A2 (en) * 2004-07-07 2006-01-12 EGIS Gyógyszergyár Rt. New pseudopolymorph of desloratadine formed with carbon dioxide
CA2541045A1 (en) * 2006-03-24 2007-09-24 Pharmascience Inc. A descarbonylethoxyloratadine containing pharmaceutical composition
EP2837631A1 (en) * 2013-08-14 2015-02-18 Merck & Cie New stable salt of 5,10-methylene-(6R)-tetrahydrofolic acid
KR102567448B1 (ko) * 2019-10-31 2023-08-17 (주)제이디바이오사이언스 삼환식 화합물 및 이의 약학적 용도
CN115785065A (zh) * 2022-12-02 2023-03-14 山东达因海洋生物制药股份有限公司 一种地氯雷他定共晶及其制备方法与应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4282233B1 (en) * 1980-06-19 2000-09-05 Schering Corp Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines
WO1985003707A1 (en) * 1984-02-15 1985-08-29 Schering Corporation 8-CHLORO-6,11-DIHYDRO-11-(4-PIPERIDYLIDENE)-5H-BENZO AD5,6 BDCYCLOHEPTA AD1,2-b BDPYRIDINE AND ITS SALTS, PROCESSES FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS
DE3677842D1 (de) * 1985-05-13 1991-04-11 Schering Corp Verfahren zur herstellung von piperidyliden-dihydrodibenzo(a,d)zykloheptenen und deren azoderivate, so hergestellte verbindungen und ihre anwendung zur vorbereitung von heilmitteln.
PT656348E (pt) * 1993-12-03 2000-10-31 Hoffmann La Roche Derivados do acido acetico como medicamentos
GB9709945D0 (en) * 1997-05-17 1997-07-09 Glaxo Group Ltd A novel salt

Also Published As

Publication number Publication date
PL206973B1 (pl) 2010-10-29
US20050203116A1 (en) 2005-09-15
DK1347965T3 (da) 2006-06-06
JP2004514675A (ja) 2004-05-20
SK285715B6 (sk) 2007-06-07
US7196195B2 (en) 2007-03-27
CA2425422A1 (en) 2002-05-30
EP1347965B1 (en) 2006-01-25
CZ20031321A3 (cs) 2003-08-13
CZ304694B6 (cs) 2014-09-03
CY1105595T1 (el) 2010-07-28
CN1199968C (zh) 2005-05-04
UA74858C2 (en) 2006-02-15
NO325155B1 (no) 2008-02-11
DE60116902T2 (de) 2006-08-24
PL362126A1 (en) 2004-10-18
NO20032314D0 (no) 2003-05-22
RU2285001C2 (ru) 2006-10-10
NO20032314L (no) 2003-07-18
SK5662003A3 (en) 2003-10-07
DE60116902D1 (de) 2006-04-13
AU2002218422A1 (en) 2002-06-03
WO2002042290A1 (en) 2002-05-30
HU0004701D0 (hu) 2001-02-28
EP1347965A1 (en) 2003-10-01
JP4427249B2 (ja) 2010-03-03
ATE316525T1 (de) 2006-02-15
ES2257467T3 (es) 2006-08-01
CN1476443A (zh) 2004-02-18
CA2425422C (en) 2009-11-10
HU226998B1 (en) 2010-04-28

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: RICHTER GEDEON NYRT., HU

Free format text: FORMER OWNER(S): RICHTER GEDEON VEGYESZETI GYAR RT., HU