HN1998000118A - 2 - aminopiridinas que contienen sustituyentes de anillos condensados. - Google Patents

2 - aminopiridinas que contienen sustituyentes de anillos condensados.

Info

Publication number
HN1998000118A
HN1998000118A HN1998000118A HN1998000118A HN1998000118A HN 1998000118 A HN1998000118 A HN 1998000118A HN 1998000118 A HN1998000118 A HN 1998000118A HN 1998000118 A HN1998000118 A HN 1998000118A HN 1998000118 A HN1998000118 A HN 1998000118A
Authority
HN
Honduras
Prior art keywords
condensed rings
containing substitutes
aminopyridines containing
aminopyridines
substitutes
Prior art date
Application number
HN1998000118A
Other languages
English (en)
Inventor
Pfizer Products Inc
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of HN1998000118A publication Critical patent/HN1998000118A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems

Abstract

LA PRESENTE INVENCION SE REFIERE A 2 - AMINOPIRIDINAS QUE CONTIENEN SUSTITUYENTES DE ANILLOS CONDENSADOS..
HN1998000118A 1997-08-27 1998-07-29 2 - aminopiridinas que contienen sustituyentes de anillos condensados. HN1998000118A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5709497P 1997-08-27 1997-08-27

Publications (1)

Publication Number Publication Date
HN1998000118A true HN1998000118A (es) 1999-02-09

Family

ID=22008463

Family Applications (1)

Application Number Title Priority Date Filing Date
HN1998000118A HN1998000118A (es) 1997-08-27 1998-07-29 2 - aminopiridinas que contienen sustituyentes de anillos condensados.

Country Status (40)

Country Link
EP (1) EP1007520B1 (es)
JP (1) JP3411271B2 (es)
KR (1) KR100367277B1 (es)
CN (1) CN1268133A (es)
AP (1) AP1213A (es)
AR (1) AR014110A1 (es)
AT (1) ATE248161T1 (es)
AU (1) AU8458898A (es)
BG (1) BG104138A (es)
BR (1) BR9811555A (es)
CA (1) CA2296313C (es)
CO (1) CO4970728A1 (es)
DE (1) DE69817584T2 (es)
DK (1) DK1007520T3 (es)
DZ (1) DZ2594A1 (es)
EA (1) EA003839B1 (es)
ES (1) ES2203976T3 (es)
GT (1) GT199800128A (es)
HN (1) HN1998000118A (es)
HR (1) HRP980470A2 (es)
HU (1) HUP0003700A3 (es)
ID (1) ID24087A (es)
IL (1) IL133958A0 (es)
IS (1) IS5344A (es)
MA (1) MA26537A1 (es)
NO (1) NO20000958L (es)
NZ (1) NZ502281A (es)
OA (1) OA11288A (es)
PA (1) PA8456901A1 (es)
PE (1) PE106599A1 (es)
PL (1) PL338987A1 (es)
PT (1) PT1007520E (es)
SK (1) SK1402000A3 (es)
TN (1) TNSN98154A1 (es)
TR (1) TR200000535T2 (es)
UA (1) UA55461C2 (es)
UY (1) UY25158A1 (es)
WO (1) WO1999010339A1 (es)
YU (1) YU10900A (es)
ZA (1) ZA987726B (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20010049379A1 (en) 1997-08-27 2001-12-06 Lowe John Adams 2-aminopyridines containing fused ring substituents
PL343424A1 (en) 1998-04-10 2001-08-13 Japan Tobacco Inc Amidine compounds
OA11557A (en) * 1998-06-03 2004-05-24 Pfizer Prod Inc 2-Aminopyridines containing fused ring substituents as nitric oxide synthase inhibitors.
AU749439B2 (en) * 1998-08-11 2002-06-27 Pfizer Products Inc. New pharmaceutical uses for nos inhibitors
YU58301A (sh) 1999-02-25 2004-05-12 Pfizer Products Inc. 2-aminopiridini koji sadrže supstituente sa kondenzovanim prstenom
GB0004153D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004151D0 (en) 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel use
GB0004149D0 (en) * 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
GB0004152D0 (en) * 2000-02-23 2000-04-12 Astrazeneca Uk Ltd Novel compounds
FR2805818B1 (fr) * 2000-03-03 2002-04-26 Aventis Pharma Sa Derives d'azetidine, leur preparation et les compositions pharmaceutiques les contenant
CZ200380A3 (cs) * 2000-08-16 2004-01-14 Pharmacia & Upjohn Company Sloučeniny pro léčbu poruch spojených se závislostmi
EP1392295B1 (en) 2001-05-15 2006-05-31 F. Hoffmann-La Roche AG Carboxylic acid substituted oxazole derivatives for use as ppar-alpha and -gamma activators in the treatment of diabetes
SE0102640D0 (sv) 2001-07-31 2001-07-31 Astrazeneca Ab Novel compounds
US20030045449A1 (en) * 2001-08-15 2003-03-06 Pfizer, Inc. Pharmaceutical combinations for the treatment of neurodegenerative diseases
DE10159922A1 (de) * 2001-12-06 2003-06-26 Gruenenthal Gmbh Substituierte 2-Pyrrolidin-2-yl-1H-indol-Derivate
CA2490152C (en) 2002-07-03 2009-04-07 F. Hoffmann-La Roche Ag Oxazole derivatives and their use as insulin sensitizers
WO2004016608A1 (en) * 2002-08-14 2004-02-26 Neurosearch A/S Novel quinuclidine derivatives and their use
PL375779A1 (en) 2002-08-30 2005-12-12 F.Hoffmann-La Roche Ag Novel 2-arylthiazole compounds as pparalpha and ppargamma agonists
EP1539746B1 (en) 2002-09-12 2006-11-15 F. Hoffmann-La Roche Ag N-substituted-1h-indol-5-propionic acid compounds as ppar agonists useful for the treatment of diabetes
US20040092741A1 (en) * 2002-11-08 2004-05-13 Pfizer Inc Substituted pyridines via boronic acid coupling
ES2312819T3 (es) 2002-11-25 2009-03-01 F. Hoffmann-La Roche Ag Derivados de indolilo.
US7655657B2 (en) 2003-12-22 2010-02-02 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
US7160876B2 (en) * 2003-12-22 2007-01-09 Abbott Laboratories Fused bicycloheterocycle substituted quinuclidine derivatives
JP2008505926A (ja) * 2004-07-09 2008-02-28 グラクソ　グループ　リミテッド 抗細菌剤
CN1922176A (zh) * 2004-12-10 2007-02-28 艾博特公司 稠合的双环杂环取代的奎宁环衍生物
WO2009029617A1 (en) * 2007-08-27 2009-03-05 Kalypsys, Inc. Diarylamine-substituted quinolones useful as inducible nitric oxide synthase inhibitors
TW200924772A (en) * 2007-08-27 2009-06-16 Kalypsys Inc Heterobicyclic-substituted quinolones useful as nitric oxide synthase inhibitors
UA105182C2 (ru) 2008-07-03 2014-04-25 Ньюрексон, Інк. Бензоксазины, бензотиазины и родственные соединения, которые имеют ингибирующую nos активность
DE102008054141A1 (de) 2008-10-31 2010-05-06 Merck Patent Gmbh Neue Materialien für organische Elektrolumineszenzvorrichtungen
DE102009033371A1 (de) 2009-07-16 2011-05-12 Merck Patent Gmbh Materialien für elektronische Vorrichtungen
US9120750B2 (en) 2013-03-07 2015-09-01 Northwestern University 2-Aminopyridine-based selective neuronal nitric oxide synthase inhibitors
CN104725249B (zh) * 2013-12-20 2019-02-12 广东东阳光药业有限公司 苄胺类衍生物及其在药物上的应用
US10759791B2 (en) 2014-11-04 2020-09-01 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
US9951014B2 (en) 2014-11-04 2018-04-24 Northwestern University Mammalian and bacterial nitric oxide synthase inhibitors
CN106478376A (zh) * 2016-10-08 2017-03-08 贵州大学 一种4‑氟萘‑1‑醇的制备工艺
CN114560779A (zh) * 2022-01-25 2022-05-31 杭州华东医药集团浙江华义制药有限公司 一种米拉贝隆关键中间体的合成方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT400845B (de) * 1993-12-06 1996-03-25 Chem Pharm Forsch Gmbh Neue thienothiazinderivate, ein verfahren zu ihrer herstellung und ihre verwendung
AU4515696A (en) * 1994-12-12 1996-07-03 Merck & Co., Inc. Substituted 2-aminopyridines as inhibitors of nitric oxide synthase
JPH08311028A (ja) * 1995-05-17 1996-11-26 Japan Tobacco Inc ２−アミノピリジン誘導体及びそれら化合物を含有してなる一酸化窒素合成酵素阻害剤
JPH09132529A (ja) * 1995-11-09 1997-05-20 Ono Pharmaceut Co Ltd 一酸化窒素合成酵素阻害剤
JP3455229B2 (ja) * 1996-03-29 2003-10-14 ファイザー インク． ６―フェニルピリジル―２―アミン誘導体
HN1997000027A (es) * 1996-12-06 1997-06-05 Pfizer Prod Inc Derivados de 6-fenil piridil - 2 amina

Also Published As

Publication number Publication date
KR100367277B1 (ko) 2003-01-09
HRP980470A2 (en) 1999-06-30
CA2296313A1 (en) 1999-03-04
GT199800128A (es) 2000-02-01
HUP0003700A2 (hu) 2001-10-28
JP2001514176A (ja) 2001-09-11
WO1999010339A1 (en) 1999-03-04
DE69817584D1 (de) 2003-10-02
CA2296313C (en) 2004-11-02
KR20010022433A (ko) 2001-03-15
IS5344A (is) 2000-01-14
SK1402000A3 (en) 2000-07-11
EA200000171A1 (ru) 2000-10-30
AR014110A1 (es) 2001-02-07
HUP0003700A3 (en) 2002-09-30
EP1007520B1 (en) 2003-08-27
PA8456901A1 (es) 2000-05-24
ID24087A (id) 2000-07-06
AP1213A (en) 2003-10-07
MA26537A1 (fr) 2004-12-20
YU10900A (sh) 2002-12-10
EP1007520A1 (en) 2000-06-14
BR9811555A (pt) 2000-09-12
DE69817584T2 (de) 2004-04-01
BG104138A (en) 2000-11-30
NO20000958D0 (no) 2000-02-25
PE106599A1 (es) 1999-11-02
DK1007520T3 (da) 2003-11-24
PL338987A1 (en) 2000-12-04
PT1007520E (pt) 2003-12-31
EA003839B1 (ru) 2003-10-30
NZ502281A (en) 2002-09-27
CN1268133A (zh) 2000-09-27
AU8458898A (en) 1999-03-16
TNSN98154A1 (fr) 2005-03-15
TR200000535T2 (tr) 2000-11-21
UY25158A1 (es) 2000-12-29
DZ2594A1 (fr) 2003-02-22
IL133958A0 (en) 2001-04-30
CO4970728A1 (es) 2000-11-07
ATE248161T1 (de) 2003-09-15
OA11288A (en) 2003-08-22
ZA987726B (en) 2000-02-28
JP3411271B2 (ja) 2003-05-26
NO20000958L (no) 2000-04-14
UA55461C2 (uk) 2003-04-15
ES2203976T3 (es) 2004-04-16
AP9801330A0 (en) 1998-09-30

Similar Documents

Publication Publication Date Title
HN1998000118A (es) 2 - aminopiridinas que contienen sustituyentes de anillos condensados.
HN1997000097A (es) Piridinas condensadas con heterociclicos
HN1997000090A (es) Compuestos de piridilpirrol
HN1998000086A (es) Derivados de 9 - desofo - 9 aza - 9a - homoeritromicina a - c - 4 sustituidos.
HN1998000175A (es) Imidazotriazininas
HN1997000023A (es) Derivados de lactama
HN1998000036A (es) Compuesto de pirazina
HN1999000155A (es) 4-carboxiamino-2-metil-1,2,3,4-tetrahidroquinolinas
HN1997000126A (es) Derivados de indazol
HN1997000166A (es) 1-arilpirazoles plaguicidas
HN1998000011A (es) Derivados de acidos arilsulfonilaminohidroxamicos
HN1998000177A (es) Compuestos azopoliciclicos condensados con arilo
HN1999000066A (es) Formulaciones farmaceuticas
HN1999000154A (es) 1,2,3,4 tetrahidroquinolinas 2 sustituidas 4 - carboxiamino sustituidas.
HN1997000099A (es) Inhibidores de metaloproteasas matriciales basados en
HN1998000124A (es) Terapia de combinacion
HN1996000101A (es) Terapia combinada para la osteoporosis
HN1998003689A (es) Azetidinas
HN1998000030A (es) 2-amino-6-(4fenoxi-2-sustituido)-piridinas sustituidas
SV1999000060A (es) Procedimiento para la preparacion de (s,s)-bencil-2,8-diazabiciclo 4.3.0 nonano ref. 32965-sv
HN1998000106A (es) Composiciones parenterales de alatroflaxacino
HN1998000028A (es) Otropisomeros de 3 heteroaril - 4 (3h) - quinazolinonas.
HN1998000045A (es) Composiciones farmaceuticas
HN1998000193A (es) Compuestos de triazina
HN1997000138A (es) Caramelo juguete