HK1219950A1 - 作爲激酶抑制劑的吡咯並吡啶 - Google Patents

作爲激酶抑制劑的吡咯並吡啶

Info

Publication number: HK1219950A1
Authority: HK; Hong Kong
Prior art keywords: pyrrolopyridines; kinase inhibitors; kinase; inhibitors
Prior art date: 2008-05-13

Application number

HK16107983.6A

Other languages

English (en)

Inventor

Huerou Yvan Le

James F Blake

Indrani W Gunwardana

Peter J Mohr

Eli M Wallace

Bin Wang

Mark Chicarelli

Michael Lyon

Original Assignee

Array Biopharma Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-05-13

Filing date

2016-07-08

Publication date

2017-04-21

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40810786&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1219950(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2016-07-08 Application filed by Array Biopharma Inc filed Critical Array Biopharma Inc

2017-04-21 Publication of HK1219950A1 publication Critical patent/HK1219950A1/zh

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

HK16107983.6A 2008-05-13 2016-07-08 作爲激酶抑制劑的吡咯並吡啶 HK1219950A1 (zh)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US5292608P	2008-05-13	2008-05-13

Publications (1)

Publication Number	Publication Date
HK1219950A1 true HK1219950A1 (zh)	2017-04-21

Family

ID=40810786

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
HK11106054.7A HK1152035A1 (zh)	2008-05-13	2011-06-14	作為激酶抑制劑的吡咯並吡啶
HK16107983.6A HK1219950A1 (zh)	2008-05-13	2016-07-08	作爲激酶抑制劑的吡咯並吡啶

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
HK11106054.7A HK1152035A1 (zh)	2008-05-13	2011-06-14	作為激酶抑制劑的吡咯並吡啶

Country Status (30)

Country	Link
US (6)	US8178131B2 (zh)
EP (2)	EP2307409B1 (zh)
JP (2)	JP5703212B2 (zh)
KR (2)	KR101643426B1 (zh)
CN (3)	CN104926810B (zh)
AR (1)	AR071717A1 (zh)
AU (1)	AU2009246402B2 (zh)
BR (1)	BRPI0913580B8 (zh)
CA (1)	CA2724262C (zh)
CL (1)	CL2009001152A1 (zh)
CO (1)	CO6321244A2 (zh)
CR (1)	CR11803A (zh)
CY (1)	CY1116692T1 (zh)
DK (1)	DK2307409T3 (zh)
ES (1)	ES2552643T3 (zh)
HK (2)	HK1152035A1 (zh)
HR (1)	HRP20151018T1 (zh)
HU (1)	HUE026160T2 (zh)
IL (1)	IL209258A (zh)
MX (1)	MX2010012449A (zh)
NZ (1)	NZ589318A (zh)
PH (1)	PH12013501779A1 (zh)
PL (1)	PL2307409T3 (zh)
PT (1)	PT2307409E (zh)
RS (1)	RS54358B1 (zh)
RU (1)	RU2517194C2 (zh)
SI (1)	SI2307409T1 (zh)
TW (2)	TWI458727B (zh)
UA (1)	UA111933C2 (zh)
WO (1)	WO2009140320A1 (zh)

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JP2009256298A (ja) *	2008-03-26	2009-11-05	Sumitomo Chemical Co Ltd	ピペリジン−３−イルカーバメート化合物の光学分割方法およびその中間体
CL2009001152A1 (es) *	2008-05-13	2009-10-16	Array Biopharma Inc	Compuestos derivados de n-(4-(cicloalquilo nitrogenado-1-il)-1h-pirrolo[2,3-b]piridin-3-il)amida, inhibidores de cinasa; proceso de preparacion; composicion farmaceutica; y su uso para el tratamiento de una enfermedad proliferativa.
US8481557B2 (en)	2009-04-11	2013-07-09	Array Biopharma Inc.	Method of treatment using checkpoint kinase 1 inhibitors
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US9370567B2 (en) *	2010-11-16	2016-06-21	Array Biopharma Inc.	Combination of checkpoint kinase 1 inhibitors and WEE 1 kinase inhibitors
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CN105722838B (zh)	2013-09-25	2017-10-24	沃泰克斯药物股份有限公司	磷脂酰肌醇3‑激酶‑γ的选择性抑制剂
CA2946538A1 (en)	2014-04-04	2015-10-08	Del Mar Pharmaceuticals	Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
TW201613919A (en)	2014-07-02	2016-04-16	Pharmacyclics Llc	Inhibitors of Bruton's tyrosine kinase
MA41599A (fr) *	2015-02-26	2018-01-02	Array Biopharma Inc	Formes cristallines d'un composé pyrrolopyridine
WO2017003090A1 (ko)	2015-06-30	2017-01-05	서울바이오시스 주식회사	Uv led가 적용된 포충기
KR20180073599A (ko)	2015-11-04	2018-07-02	메르크 파텐트 게엠베하	Btk 억제 활성을 갖는 피리미딘 및 피리딘 화합물을 사용하여 암 치료하는 방법
US20190010167A1 (en) *	2015-12-22	2019-01-10	Vitae Pharmaceuticals, Inc.	Inhibitors of the menin-mll interaction
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EP3461480A1 (en)	2017-09-27	2019-04-03	Onxeo	Combination of a dna damage response cell cycle checkpoint inhibitors and belinostat for treating cancer
CN112823036A (zh)	2018-07-03	2021-05-18	艾福姆德尤股份有限公司	用于治疗与sting活性有关的疾病的化合物和组合物
CN109053526A (zh) *	2018-08-13	2018-12-21	南通大学	一种（3r，4s）-4-甲基吡咯烷-3-基氨基甲酸叔丁酯盐酸盐的化学合成方法
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TW202043198A (zh)	2019-01-17	2020-12-01	美商ＩｆｍＤｕｅ有限公司	用於治療與sting活性相關之病況的化合物及組合物
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CL2009001152A1 (es)	2008-05-13	2009-10-16	Array Biopharma Inc	Compuestos derivados de n-(4-(cicloalquilo nitrogenado-1-il)-1h-pirrolo[2,3-b]piridin-3-il)amida, inhibidores de cinasa; proceso de preparacion; composicion farmaceutica; y su uso para el tratamiento de una enfermedad proliferativa.
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2009
- 2009-05-12 CL CL2009001152A patent/CL2009001152A1/es unknown
- 2009-05-12 AR ARP090101708A patent/AR071717A1/es active IP Right Grant
- 2009-05-13 ES ES09747404.3T patent/ES2552643T3/es active Active
- 2009-05-13 TW TW098115906A patent/TWI458727B/zh active
- 2009-05-13 DK DK09747404.3T patent/DK2307409T3/en active
- 2009-05-13 AU AU2009246402A patent/AU2009246402B2/en not_active Ceased
- 2009-05-13 HU HUE09747404A patent/HUE026160T2/en unknown
- 2009-05-13 RS RS20150711A patent/RS54358B1/en unknown
- 2009-05-13 PL PL09747404T patent/PL2307409T3/pl unknown
- 2009-05-13 CN CN201510289964.7A patent/CN104926810B/zh active Active
- 2009-05-13 KR KR1020107027941A patent/KR101643426B1/ko active IP Right Grant
- 2009-05-13 TW TW103133772A patent/TWI554512B/zh active
- 2009-05-13 WO PCT/US2009/043691 patent/WO2009140320A1/en active Application Filing
- 2009-05-13 RU RU2010150786/04A patent/RU2517194C2/ru active
- 2009-05-13 CN CN201910068067.1A patent/CN109942575A/zh active Pending
- 2009-05-13 US US12/992,468 patent/US8178131B2/en active Active
- 2009-05-13 MX MX2010012449A patent/MX2010012449A/es active IP Right Grant
- 2009-05-13 BR BRPI0913580A patent/BRPI0913580B8/pt not_active IP Right Cessation
- 2009-05-13 EP EP09747404.3A patent/EP2307409B1/en active Active
- 2009-05-13 KR KR1020147015705A patent/KR101657856B1/ko active IP Right Grant
- 2009-05-13 UA UAA201015012A patent/UA111933C2/uk unknown
- 2009-05-13 EP EP15175131.0A patent/EP2990407B1/en active Active
- 2009-05-13 PT PT97474043T patent/PT2307409E/pt unknown
- 2009-05-13 CN CN200980127299.4A patent/CN102089307B/zh active Active
- 2009-05-13 NZ NZ589318A patent/NZ589318A/en not_active IP Right Cessation
- 2009-05-13 CA CA2724262A patent/CA2724262C/en active Active
- 2009-05-13 JP JP2011509628A patent/JP5703212B2/ja not_active Expired - Fee Related
- 2009-05-13 SI SI200931284T patent/SI2307409T1/sl unknown
2010
- 2010-11-11 IL IL209258A patent/IL209258A/en active IP Right Grant
- 2010-11-19 CR CR11803A patent/CR11803A/es unknown
- 2010-11-30 CO CO10150963A patent/CO6321244A2/es active IP Right Grant
2011
- 2011-06-14 HK HK11106054.7A patent/HK1152035A1/zh not_active IP Right Cessation
2012
- 2012-03-20 US US13/425,186 patent/US8545897B2/en active Active
2013
- 2013-08-23 US US13/974,895 patent/US8758830B2/en active Active
- 2013-08-28 PH PH12013501779A patent/PH12013501779A1/en unknown
2014
- 2014-05-06 US US14/271,129 patent/US8981085B2/en active Active
2015
- 2015-01-07 US US14/591,691 patent/US9365568B2/en active Active
- 2015-02-23 JP JP2015032474A patent/JP2015098482A/ja not_active Withdrawn
- 2015-09-16 CY CY20151100812T patent/CY1116692T1/el unknown
- 2015-09-28 HR HRP20151018TT patent/HRP20151018T1/hr unknown
2016
- 2016-01-05 US US14/988,521 patent/US9969727B2/en active Active
- 2016-07-08 HK HK16107983.6A patent/HK1219950A1/zh unknown

Also Published As

Publication number	Publication date
TW201002707A (en)	2010-01-16
PL2307409T3 (pl)	2016-01-29
US9365568B2 (en)	2016-06-14
KR20110008102A (ko)	2011-01-25
HRP20151018T1 (hr)	2015-10-23
CA2724262C (en)	2017-08-15
US9969727B2 (en)	2018-05-15
US20140243520A1 (en)	2014-08-28
CN104926810B (zh)	2019-02-19
MX2010012449A (es)	2011-05-25
CN104926810A (zh)	2015-09-23
RU2517194C2 (ru)	2014-05-27
CN102089307A (zh)	2011-06-08
SI2307409T1 (sl)	2015-11-30
CN102089307B (zh)	2015-07-01
US8545897B2 (en)	2013-10-01
BRPI0913580B1 (pt)	2020-03-10
UA111933C2 (uk)	2016-07-11
US20160368916A1 (en)	2016-12-22
US20110070317A1 (en)	2011-03-24
US20150322061A1 (en)	2015-11-12
US8758830B2 (en)	2014-06-24
BRPI0913580B8 (pt)	2021-05-25
US20130045286A1 (en)	2013-02-21
KR101643426B1 (ko)	2016-07-27
ES2552643T3 (es)	2015-12-01
JP2015098482A (ja)	2015-05-28
EP2990407B1 (en)	2019-10-16
NZ589318A (en)	2011-06-30
HUE026160T2 (en)	2016-05-30
CY1116692T1 (el)	2017-03-15
AU2009246402A1 (en)	2009-11-19
BRPI0913580A2 (pt)	2015-10-20
IL209258A0 (en)	2011-01-31
JP2011520896A (ja)	2011-07-21
TW201529573A (zh)	2015-08-01
AR071717A1 (es)	2010-07-07
TWI458727B (zh)	2014-11-01
KR101657856B1 (ko)	2016-09-19
US8178131B2 (en)	2012-05-15
CL2009001152A1 (es)	2009-10-16
WO2009140320A1 (en)	2009-11-19
KR20140093266A (ko)	2014-07-25
AU2009246402B2 (en)	2013-05-23
CA2724262A1 (en)	2009-11-19
US20140100369A1 (en)	2014-04-10
IL209258A (en)	2017-01-31
CO6321244A2 (es)	2011-09-20
EP2990407A1 (en)	2016-03-02
US8981085B2 (en)	2015-03-17
RU2010150786A (ru)	2012-06-20
EP2307409B1 (en)	2015-08-12
DK2307409T3 (en)	2015-09-21
EP2307409A1 (en)	2011-04-13
PH12013501779B1 (en)	2014-08-27
JP5703212B2 (ja)	2015-04-15
CN109942575A (zh)	2019-06-28
PT2307409E (pt)	2015-11-04
CR11803A (es)	2011-02-11
HK1152035A1 (zh)	2012-02-17
PH12013501779A1 (en)	2014-08-27
TWI554512B (zh)	2016-10-21
RS54358B1 (en)	2016-04-28

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