HK1009807A1 - Intermediates and process for preparing olanzapine - Google Patents

Intermediates and process for preparing olanzapine

Info

Publication number
HK1009807A1
HK1009807A1 HK98110796A HK98110796A HK1009807A1 HK 1009807 A1 HK1009807 A1 HK 1009807A1 HK 98110796 A HK98110796 A HK 98110796A HK 98110796 A HK98110796 A HK 98110796A HK 1009807 A1 HK1009807 A1 HK 1009807A1
Authority
HK
Hong Kong
Prior art keywords
intermediates
preparing olanzapine
olanzapine
preparing
Prior art date
Application number
HK98110796A
Other languages
English (en)
Inventor
Charles Arthur Bunnell
Samuel Dean Larsen
John Richard Nichols
Susan Marie Reutzel
Gregory Alan Stephenson
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21832120&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1009807(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of HK1009807A1 publication Critical patent/HK1009807A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
HK98110796A 1996-09-23 1998-09-21 Intermediates and process for preparing olanzapine HK1009807A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US2648796P 1996-09-23 1996-09-23

Publications (1)

Publication Number Publication Date
HK1009807A1 true HK1009807A1 (en) 1999-06-11

Family

ID=21832120

Family Applications (1)

Application Number Title Priority Date Filing Date
HK98110796A HK1009807A1 (en) 1996-09-23 1998-09-21 Intermediates and process for preparing olanzapine

Country Status (36)

Country Link
US (1) US6020487A (zh)
EP (1) EP0831098B1 (zh)
JP (2) JP2001500877A (zh)
KR (1) KR100560015B1 (zh)
CN (1) CN1122036C (zh)
AR (1) AR013838A1 (zh)
AT (1) ATE209208T1 (zh)
AU (1) AU719441B2 (zh)
BR (1) BR9712100A (zh)
CA (1) CA2265712C (zh)
CO (1) CO4910140A1 (zh)
CZ (1) CZ299248B6 (zh)
DE (1) DE69708428T2 (zh)
DK (1) DK0831098T3 (zh)
EA (1) EA001642B1 (zh)
EG (1) EG23861A (zh)
ES (1) ES2166051T3 (zh)
HK (1) HK1009807A1 (zh)
HU (1) HU226484B1 (zh)
ID (1) ID27275A (zh)
IL (1) IL128962A (zh)
IN (1) IN187156B (zh)
MY (1) MY125565A (zh)
NO (1) NO323980B1 (zh)
NZ (1) NZ334448A (zh)
PE (1) PE110398A1 (zh)
PL (3) PL196068B1 (zh)
PT (1) PT831098E (zh)
RS (1) RS49598B (zh)
SI (1) SI0831098T1 (zh)
SV (1) SV1997000081A (zh)
TR (1) TR199900640T2 (zh)
TW (1) TW470746B (zh)
UA (1) UA59371C2 (zh)
WO (1) WO1998012199A1 (zh)
ZA (1) ZA978515B (zh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL154688A0 (en) * 2000-08-31 2003-09-17 Reddys Lab Ltd Dr Hydrates of olanzapine and processes for the preparation thereof
US6740753B2 (en) * 2001-01-04 2004-05-25 Geneva Pharmaceuticals, Inc. Olanzapine crystal modification
WO2003037903A1 (en) * 2001-10-29 2003-05-08 Dr. Reddy's Laboratories Ltd. Olanzapine dihydrate-ii a process for its preparation and use thereof
WO2003055438A2 (en) 2001-12-24 2003-07-10 Sun Pharmaceutical Industries Limited Crystalline form i of 2-methyl-4-(4-methyl-1-piperazinyl) 10h thieno [2,3-b][1,5]benzodiazepine
AU2003243153A1 (en) * 2002-04-23 2003-11-10 Dr. Reddy's Laboratories Limited Novel crystalline polymorph form-vi of olanzapine and a process for preparation thereof
EP1513846B1 (en) 2002-05-31 2011-03-02 Sandoz Ag Process of preparation of olanzapine form i
SI21270A (sl) 2002-07-15 2004-02-29 Krka, Tovarna Zdravil, D.D., Novo Mesto Kristalne oblike olanzapina in postopki za njihovo pripravo
WO2004058773A1 (en) * 2002-12-24 2004-07-15 Teva Pharmaceutical Industries Ltd. Novel crystal forms of olanzapine, methods for their preparation and method for the preparation of known olanzapine crystal forms
JP2007511605A (ja) * 2003-11-18 2007-05-10 スリーエム イノベイティブ プロパティズ カンパニー オランザピン含有経皮薬物送達組成物
DE602004014264D1 (de) * 2003-12-22 2008-07-17 Teva Pharma Verfahren zur herstellung von olanzapin
WO2005070938A1 (en) 2004-01-27 2005-08-04 Synthon B.V. Stable salts of olanzapine
EP1716154A1 (en) * 2004-02-19 2006-11-02 Neuland Laboratories Ltd Process for the preparation of olanzapine form 1 useful as antipsychotic drug
WO2006006185A1 (en) * 2004-07-14 2006-01-19 Shasun Chemicals And Drugs Limited Improved process for making form i of olanzapine.
ES2253091B1 (es) 2004-07-27 2007-02-01 Inke, S.A. Solvato mixto de olanzapina, procedimiento para su obtencion y procedimiento de obtencion de la forma i de olanzapina a partir del mismo.
DE112005000641T5 (de) 2004-09-06 2007-09-06 Shasun Chemicals and Drugs Ltd., Chennai Neues Verfahren zur Herstellung einer pharmazeutisch reinen polymorphen Form I von Olanzapin
CA2587710C (en) * 2004-11-16 2014-10-21 Elan Pharma International Ltd. Injectable nanoparticulate olanzapine formulations
US7834176B2 (en) 2006-01-26 2010-11-16 Sandoz Ag Polymorph E of Olanzapine and preparation of anhydrous non-solvated crystalline polymorphic Form I of 2-methyl-4(4-methyl-1-piperazinyl)-10H-thieno[2,3-b][1,5] benzodiazepine (Olanzapine Form I) from the polymorphic Olanzapine Form E
CA2591644A1 (en) * 2007-06-14 2008-12-14 Apotex Pharmachem Inc. Novel processes to form-i of olanzapine
EP2486913A1 (en) 2011-02-14 2012-08-15 Labtec GmbH Rapidly disintegrating oral film formulation for Olanzapin
JP6008734B2 (ja) * 2012-12-20 2016-10-19 株式会社トクヤマ オランザピンｉｉ型結晶の製造方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302716A (en) * 1986-01-16 1994-04-12 Schering Corporation Fused benzazepines
CA2002596A1 (en) * 1988-11-14 1990-05-14 Thomas M. Eckrich Hydrates of b-lactam antibiotic
GB9009229D0 (en) * 1990-04-25 1990-06-20 Lilly Industries Ltd Pharmaceutical compounds
US5229382A (en) * 1990-04-25 1993-07-20 Lilly Industries Limited 2-methyl-thieno-benzodiazepine
AU668159B2 (en) * 1992-05-29 1996-04-26 Lilly Industries Limited Pharmaceutical compounds
US5550231A (en) * 1993-06-15 1996-08-27 Eli Lilly And Company Loracarbef hydrochloride C1-C3 alcohol solvates and uses thereof
US5602124A (en) * 1994-12-12 1997-02-11 Allelix Biopharmaceuticals, Inc. 5-HT2 receptor ligands
US5637584A (en) * 1995-03-24 1997-06-10 Eli Lilly And Company Solvate of olanzapine
US5631250A (en) * 1995-03-24 1997-05-20 Eli Lilly And Company Process and solvate of 2-methyl-thieno-benzodiazepine
EG24221A (en) * 1995-03-24 2008-11-10 Lilly Co Eli Process for preparing olanzapine
EG23659A (en) * 1995-03-24 2007-03-26 Lilly Co Eli Process and crystal forms of methyl-thieno-benzodiazepine
RS49597B (sr) * 1996-09-23 2007-06-04 Eli Lilly And Company, Olanzapin dihidrat d

Also Published As

Publication number Publication date
DE69708428T2 (de) 2002-07-04
SI0831098T1 (en) 2002-04-30
ATE209208T1 (de) 2001-12-15
NZ334448A (en) 2000-08-25
WO1998012199A1 (en) 1998-03-26
CZ299248B6 (cs) 2008-05-28
DK0831098T3 (da) 2002-05-21
SV1997000081A (es) 1999-01-14
NO323980B1 (no) 2007-07-30
TR199900640T2 (xx) 1999-06-21
ID27275A (id) 2001-03-22
CN1122036C (zh) 2003-09-24
EP0831098B1 (en) 2001-11-21
KR100560015B1 (ko) 2006-03-15
PL194565B1 (pl) 2007-06-29
EP0831098A2 (en) 1998-03-25
YU15599A (sh) 2001-12-26
EA001642B1 (ru) 2001-06-25
IN187156B (zh) 2002-02-16
NO991382D0 (no) 1999-03-22
NO991382L (no) 1999-03-22
IL128962A0 (en) 2000-02-17
ES2166051T3 (es) 2002-04-01
CO4910140A1 (es) 2000-04-24
EP0831098A3 (en) 1998-04-29
CZ99099A3 (cs) 1999-11-17
HU226484B1 (en) 2009-03-02
PE110398A1 (es) 1999-01-14
AR013838A1 (es) 2001-01-31
PL332482A1 (en) 1999-09-13
EG23861A (en) 2007-11-18
UA59371C2 (uk) 2003-09-15
ZA978515B (en) 1999-03-23
DE69708428D1 (de) 2002-01-03
BR9712100A (pt) 1999-08-31
HUP0000066A2 (hu) 2000-06-28
RS49598B (sr) 2007-06-04
AU4484197A (en) 1998-04-14
CA2265712C (en) 2006-10-31
PL196068B1 (pl) 2007-12-31
CA2265712A1 (en) 1998-03-26
MY125565A (en) 2006-08-30
PT831098E (pt) 2002-04-29
HUP0000066A3 (en) 2000-11-28
AU719441B2 (en) 2000-05-11
PL196069B1 (pl) 2007-12-31
CN1234802A (zh) 1999-11-10
JP2009242407A (ja) 2009-10-22
EA199900326A1 (ru) 1999-08-26
JP2001500877A (ja) 2001-01-23
IL128962A (en) 2003-01-12
KR20000048520A (ko) 2000-07-25
TW470746B (en) 2002-01-01
US6020487A (en) 2000-02-01

Similar Documents

Publication Publication Date Title
AP9901444A0 (en) Erythrommycins and process for their preparation
HUP9800208A3 (en) Omega-cycloalkyl-prostaglandin e2-derivatives and process for preparing them
GB9609441D0 (en) Process
EG23861A (en) Intermediates and process for preparing olanzapine
HU9702508D0 (en) Vitronectin-receptor-antagonists and process for producing them
EP0880388A4 (en) RETURNING HYDRATION PROCESS
HU9702509D0 (en) Vitronectin-receptor-antagonists and process for producing them
ZA9711523B (en) Continuous fermentation process
HU9602105D0 (en) Intermediate and process for making
IL118992A0 (en) Process and intermediates for preparing norbenzomorphan derivatives
HUP0001813A3 (en) Process for preparing eprosartan and intermediates
HUP0003019A3 (en) Process for preparing 4-substituted-1h-indole-3-glyoxamides and their intermediates
PL321699A1 (en) Tempering process
GB9602046D0 (en) Process
HUP0001444A3 (en) Process for preparing carboxamido-4-azasteroids and their intermediates
GB2319771B (en) Process
GB9626570D0 (en) Process for making benzisothiazolin-3-ones
EP0990639A4 (en) PROCESS FOR PRODUCING N-CYCLOPROPYLANILINES AND INTERMEDIATES USED IN THIS PROCESS
HUP9904112A3 (en) Process for preparing amidines
GB2316403B (en) Process
GB9610666D0 (en) Milk-shakes and process for making them
HUP9801594A3 (en) Novel seco-azalides and process for preparing them
IL141354A0 (en) Hydroxyphenyl-hydroximinomethyl-dioxazines and process for preparing them
GB9610470D0 (en) Article making method
HUP9903692A3 (en) Process for making dihydropyrimidinones

Legal Events

Date Code Title Description
PF Patent in force
PC Patent ceased (i.e. patent has lapsed due to the failure to pay the renewal fee)

Effective date: 20050922