ES2092438A1 - Procedimiento para la fabricacion de derivados de fenol orto-isopropilados. - Google Patents
Procedimiento para la fabricacion de derivados de fenol orto-isopropilados.Info
- Publication number
- ES2092438A1 ES2092438A1 ES09401085A ES9401085A ES2092438A1 ES 2092438 A1 ES2092438 A1 ES 2092438A1 ES 09401085 A ES09401085 A ES 09401085A ES 9401085 A ES9401085 A ES 9401085A ES 2092438 A1 ES2092438 A1 ES 2092438A1
- Authority
- ES
- Spain
- Prior art keywords
- phenol derivatives
- viii
- ortho
- producing
- isopropylated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
- C07C39/06—Alkylated phenols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
- C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
- C07D307/83—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
- C07C37/01—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis
- C07C37/055—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by replacing functional groups bound to a six-membered aromatic ring by hydroxy groups, e.g. by hydrolysis the substituted group being bound to oxygen, e.g. ether group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
- C07C39/02—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring monocyclic with no unsaturation outside the aromatic ring
- C07C39/04—Phenol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/16—Preparation of ethers by reaction of esters of mineral or organic acids with hydroxy or O-metal groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
- C07C41/01—Preparation of ethers
- C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/40—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation with ozone; by ozonolysis
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA FABRICACION DE DERIVADOS DE FENOL ORTO-ISOPROPILADOS. ESTA INVENCION SE REFIERE A EL PROCESO PARA LA PRODUCCION DE DERIVADOS DE FENOL ORTO-ISOPROPILADOS DE FORMULA GENERAL (VIII) (EN DICHA FORMULA, R1 ES UN HIDROGENO O UN GRUPO ALQUILO INFERIOR DE C1-C4). EL PROCESO COMPRENDE LA OBTENCION DE LA POSICION ISOMERA DESEADA MEDIANTE TRANSPOSICION DE CLAISEN DE FENIL ALIL ETER SIN CATALIZADOR EN LA ATMOSFERA, Y OBTENIENDO A CONTINUACION SOLAMENTE UN ISOMERO POR OXIDACION Y REDUCCION DEL ISOMERO POSICIONAL OBTENIDO ANTERIORMENTE. DE ACUERDO CON LA PRESENTE INVENCION, LOS DERIVADOS DE FENOL ORTO-ISOPROPILADOS (VIII) CON ELEVADA PUREZA A BAJA TEMPERATURA Y BAJA PRESION PUEDEN SER PREPARADOS SIN GENERAR SUBPRODUCTOS NI REQUERIR COMPLICADOS PROCESOS DE SEPARACION.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019930018007A KR960008645B1 (ko) | 1993-09-08 | 1993-09-08 | 오르토-이소프로필화 페놀 유도체의 제조방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2092438A1 true ES2092438A1 (es) | 1996-11-16 |
ES2092438B1 ES2092438B1 (es) | 1997-08-01 |
Family
ID=19363129
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES09401085A Expired - Lifetime ES2092438B1 (es) | 1993-09-08 | 1994-05-18 | Procedimiento para la fabricacion de derivados de fenol orto-isopropilados. |
Country Status (12)
Country | Link |
---|---|
US (1) | US5414156A (es) |
JP (1) | JPH0782196A (es) |
KR (1) | KR960008645B1 (es) |
CN (1) | CN1100084A (es) |
AU (1) | AU654096B1 (es) |
BR (1) | BR9401308A (es) |
CA (1) | CA2121434A1 (es) |
DE (1) | DE4422814A1 (es) |
ES (1) | ES2092438B1 (es) |
FR (1) | FR2709751A1 (es) |
IT (1) | IT1269961B (es) |
NL (1) | NL9401065A (es) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2470500C (en) * | 2001-12-28 | 2012-05-15 | Guilford Pharmaceuticals, Inc. | Aqueous based pharmaceutical formulations of water-soluble prodrugs of propofol |
KR100725582B1 (ko) * | 2004-06-29 | 2007-06-08 | 주식회사 동부하이텍 | 식물병원균의 생장억제활성을 갖는 알킬페놀 유도체 |
CN103086846B (zh) * | 2011-10-28 | 2015-08-19 | 中国石油化工股份有限公司 | 一种连续分离异丙基苯酚的装置及方法 |
WO2013114987A1 (ja) * | 2012-01-30 | 2013-08-08 | 小西化学工業株式会社 | ジアリルビスフェノール類の一貫製造方法 |
CN102731265B (zh) * | 2012-06-12 | 2014-12-10 | 四川百利药业有限责任公司 | 一种高纯度丙泊酚的制备方法 |
CN105384608B (zh) * | 2014-08-22 | 2019-08-16 | 四川海思科制药有限公司 | 一种异丙基苯酚衍生物及其制备方法 |
WO2016140978A1 (en) * | 2015-03-03 | 2016-09-09 | Arizona Board Of Regents On Behalf Of Arizona State University | Therapeutic compounds |
US10238626B2 (en) | 2017-01-23 | 2019-03-26 | Arizona Board Of Regents On Behalf Of Arizona State University | Therapeutic compounds |
US10238655B2 (en) | 2017-01-23 | 2019-03-26 | Arizona Board Of Regents On Behalf Of Arizona State University | Dihydroindene and tetrahydronaphthalene compounds |
US10231947B2 (en) | 2017-01-23 | 2019-03-19 | Arizona Board Of Regents On Behalf Of Arizona State University | Isochroman compounds and methods of use thereof |
CN114621103A (zh) * | 2022-04-02 | 2022-06-14 | 河南普瑞制药有限公司 | 一种硫酸沙丁胺醇的制备方法 |
CN116023238A (zh) * | 2023-03-30 | 2023-04-28 | 山东新华莎罗雅生物技术有限公司 | 具有杀菌清洁功效的4-氯-2-苄基苯酚衍生物的制备方法 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950236A (en) * | 1974-07-24 | 1976-04-13 | The United States Of America As Represented By The Secretary Of Health, Education And Welfare | Production of angular alkylated polycyclides by electrochemical annelation |
FR2303010A1 (fr) * | 1974-04-17 | 1976-10-01 | Isf Spa | Procede de preparation de derives du chromene et composes ainsi obtenus |
EP0058906A1 (en) * | 1981-02-20 | 1982-09-01 | Takasago Perfumery Co., Ltd. | 5-Methyl-2-(2'-oxo-3'-butyl) phenol and perfume compositions comprising same |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2831898A (en) * | 1954-04-29 | 1958-04-22 | Ethyl Corp | Phenol alkylation process |
US3367981A (en) * | 1963-05-10 | 1968-02-06 | Ethyl Corp | Phenol alkylation process |
US4447657A (en) * | 1982-11-10 | 1984-05-08 | Uop Inc. | Preparation of ortho-alkylated phenols |
JPS60258133A (ja) * | 1984-06-05 | 1985-12-20 | Mitsubishi Chem Ind Ltd | o−アルキルフエノ−ルの製法 |
US5175375A (en) * | 1991-10-11 | 1992-12-29 | Mobil Oil Corporation | Selective ortho propylation of phenol over large pore zeolite |
-
1993
- 1993-09-08 KR KR1019930018007A patent/KR960008645B1/ko not_active IP Right Cessation
- 1993-12-20 CN CN93112920A patent/CN1100084A/zh active Pending
- 1993-12-24 JP JP5328863A patent/JPH0782196A/ja active Pending
-
1994
- 1994-02-28 AU AU56467/94A patent/AU654096B1/en not_active Ceased
- 1994-03-28 BR BR9401308A patent/BR9401308A/pt not_active Application Discontinuation
- 1994-04-15 CA CA002121434A patent/CA2121434A1/en not_active Abandoned
- 1994-05-10 US US08/245,091 patent/US5414156A/en not_active Expired - Fee Related
- 1994-05-13 FR FR9405913A patent/FR2709751A1/fr active Pending
- 1994-05-18 ES ES09401085A patent/ES2092438B1/es not_active Expired - Lifetime
- 1994-06-27 NL NL9401065A patent/NL9401065A/nl not_active Application Discontinuation
- 1994-06-28 IT ITMI941347A patent/IT1269961B/it active IP Right Grant
- 1994-06-29 DE DE4422814A patent/DE4422814A1/de not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2303010A1 (fr) * | 1974-04-17 | 1976-10-01 | Isf Spa | Procede de preparation de derives du chromene et composes ainsi obtenus |
US3950236A (en) * | 1974-07-24 | 1976-04-13 | The United States Of America As Represented By The Secretary Of Health, Education And Welfare | Production of angular alkylated polycyclides by electrochemical annelation |
EP0058906A1 (en) * | 1981-02-20 | 1982-09-01 | Takasago Perfumery Co., Ltd. | 5-Methyl-2-(2'-oxo-3'-butyl) phenol and perfume compositions comprising same |
Non-Patent Citations (1)
Title |
---|
N. PAWLOWSKI y col. A new route to 3a,8a-DIHYDROFURO[2,3-b]BENZOFURANS. Tetrahedron Letters. Febrero 1974, Vol. 14, pßginas 1321-1323 * |
Also Published As
Publication number | Publication date |
---|---|
KR950008458A (ko) | 1995-04-17 |
DE4422814A1 (de) | 1995-03-09 |
NL9401065A (nl) | 1995-04-03 |
US5414156A (en) | 1995-05-09 |
IT1269961B (it) | 1997-04-16 |
JPH0782196A (ja) | 1995-03-28 |
ITMI941347A1 (it) | 1995-12-28 |
ITMI941347A0 (it) | 1994-06-28 |
FR2709751A1 (fr) | 1995-03-17 |
CN1100084A (zh) | 1995-03-15 |
BR9401308A (pt) | 1995-05-02 |
AU654096B1 (en) | 1994-10-20 |
KR960008645B1 (ko) | 1996-06-28 |
ES2092438B1 (es) | 1997-08-01 |
CA2121434A1 (en) | 1995-03-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2092438A1 (es) | Procedimiento para la fabricacion de derivados de fenol orto-isopropilados. | |
CA2105251A1 (en) | Novel processes for the production of 13-ether derivatives of milbemycins, and novel intermediates therefor | |
AU7116691A (en) | Process for the preparation of oxetanones | |
ES2000603A6 (es) | Un procedimiento para preparar aril-piperidino carbinoles | |
AU4543189A (en) | Chalcone derivatives and process for producing the same | |
PL333422A1 (en) | Method of obtaining benzyl ethers | |
ES440493A1 (es) | Procedimiento para la preparacion de clefinas terciarias. | |
ES2088926T3 (es) | Un procedimiento para reducir la formacion de nitrosaminas. | |
AU1037997A (en) | Process for the production of fluoromethylhexafluoroisopropylether | |
AU8252787A (en) | Process for the preparation of thienylethylamines and novel dithienylethylamines | |
BG107050A (en) | Method for the preparation of citalopram | |
EP0129252A3 (en) | Process for the preparation of optically active hydroquinone derivatives and of d-alpha-tocopherol | |
PH22418A (en) | Triazolyl alcohol derivatives | |
EP1205461A4 (en) | METHOD FOR CLEANING FLUORINATED HYDROXYL COMPOUNDS | |
BG107048A (en) | Method for the preparation of citalopram | |
GB9806409D0 (en) | Processes for preparing intermediates | |
GR3032427T3 (en) | An improved process for preparing side chain derivatives of cyclohexapeptidyl lipopeptides | |
ES2086800T3 (es) | Procedimiento para la preparacion de 6-hidroxi-2,5,7,8-tetraalquil-2-(4-aminofenoximetil)cromanos. | |
MXPA02008693A (es) | Procedimiento para producir simvastatina. | |
IL147728A0 (en) | Method for making debromohymenialdisine and analogs thereof | |
JPS57144299A (en) | Novel manufacture of 17 alpha-hydroxy-17 beta- hydroxyacetylsteroid and corresponding intermediate therefrom | |
JPS6483032A (en) | Manufacture of diene-1-ol, 9-hydroxydodecene- (10)-yl-1 tertiary butyl ether and use | |
AU591114B2 (en) | Process for the synthesis of 2,2,2-trifluoroethanol | |
TH14187EX (th) | ขบวนการผลิตอนุพันธุ์ของ ออร์โท-ไอโซโพรพิลเลเท็ตฟีนอล | |
MY126799A (en) | Process and intermediates for making 4-cyanosubstituted cyclohexanoic acids. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EC2A | Search report published |
Date of ref document: 19961116 Kind code of ref document: A1 Effective date: 19961116 |
|
FA2A | Application withdrawn |
Effective date: 19980807 |