EE05644B1 - Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG - Google Patents

Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG

Info

Publication number
EE05644B1
EE05644B1 EEP200200469A EEP200200469A EE05644B1 EE 05644 B1 EE05644 B1 EE 05644B1 EE P200200469 A EEP200200469 A EE P200200469A EE P200200469 A EEP200200469 A EE P200200469A EE 05644 B1 EE05644 B1 EE 05644B1
Authority
EE
Estonia
Prior art keywords
hcg
recombinant
purifying
purified
purification
Prior art date
Application number
EEP200200469A
Other languages
English (en)
Estonian (et)
Inventor
Paradisi Gianfranco
Rossi Mara
Scaglia Laura
Original Assignee
Applied Research Systems Ars Holding N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems Ars Holding N.V. filed Critical Applied Research Systems Ars Holding N.V.
Publication of EE200200469A publication Critical patent/EE200200469A/xx
Publication of EE05644B1 publication Critical patent/EE05644B1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/36Extraction; Separation; Purification by a combination of two or more processes of different types
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/59Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
EEP200200469A 2000-02-22 2001-01-22 Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG EE05644B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP00103690 2000-02-22
PCT/EP2001/000665 WO2001062773A1 (en) 2000-02-22 2001-01-22 PROCESS OF PURIFICATION OF hCG AND RECOMBINANT hCG PURIFIED BY THAT METHOD

Publications (2)

Publication Number Publication Date
EE200200469A EE200200469A (et) 2004-04-15
EE05644B1 true EE05644B1 (et) 2013-04-15

Family

ID=8167925

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200469A EE05644B1 (et) 2000-02-22 2001-01-22 Meetod hCG puhastamiseks ja selle meetodiga puhastatud rekombinantne hCG

Country Status (32)

Country Link
US (2) US7297777B2 (ja)
EP (2) EP1257564B1 (ja)
JP (1) JP4588960B2 (ja)
KR (1) KR100806911B1 (ja)
CN (1) CN100482679C (ja)
AT (1) ATE406378T1 (ja)
AU (2) AU783320B2 (ja)
BG (1) BG65807B1 (ja)
BR (1) BRPI0108556B8 (ja)
CA (1) CA2399020A1 (ja)
CY (1) CY1108460T1 (ja)
CZ (1) CZ303144B6 (ja)
DE (1) DE60135541D1 (ja)
DK (1) DK1257564T3 (ja)
EA (1) EA006605B1 (ja)
EE (1) EE05644B1 (ja)
ES (1) ES2307585T3 (ja)
HK (1) HK1052016A1 (ja)
HR (1) HRP20020650B1 (ja)
HU (2) HU228935B1 (ja)
IL (2) IL151308A0 (ja)
ME (1) ME00296B (ja)
MX (1) MXPA02007871A (ja)
NO (1) NO328694B1 (ja)
PL (1) PL205149B1 (ja)
PT (1) PT1257564E (ja)
RS (1) RS50741B (ja)
SI (1) SI1257564T1 (ja)
SK (1) SK287146B6 (ja)
UA (2) UA86938C2 (ja)
WO (1) WO2001062773A1 (ja)
ZA (1) ZA200206109B (ja)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ME00296B (me) * 2000-02-22 2011-05-10 Applied Res Systems Ars Holding N V PROCES PREČIŠĆAVANJA hCG I REKOMBINANTNOG hCG PREČIŠĆENOG TOM METODOM
EP1709065B1 (en) * 2004-10-04 2010-06-02 Novetide Ltd. A counterion exchange process for peptides
CN1958603B (zh) * 2005-11-04 2010-05-05 上海天伟生物制药有限公司 一种人绒毛膜促性腺素的纯化方法
WO2008007993A1 (fr) * 2006-07-11 2008-01-17 Koval, Anton Alexandrovich Utilisation d'une hormone chorionique ou lutéinisante destinée à la prévention ou au traitement de l'hypogonadisme lié à l'âge
CN101397339B (zh) * 2008-09-24 2012-07-25 上海天伟生物制药有限公司 糖蛋白中去除/灭活病毒的方法
TWI532495B (zh) 2009-10-05 2016-05-11 菲瑞茵國際中心股份有限公司 藥學製劑
CN101792481B (zh) * 2010-03-12 2012-05-30 丽珠医药集团股份有限公司 一种绒毛膜***的纯化方法
WO2012120535A2 (en) * 2011-02-03 2012-09-13 Sanzyme Limited A composition comprising highly purified chorionic gonadotropin, it's formulation and uses of the same
JP6087338B2 (ja) 2011-03-31 2017-03-01 フェリング ベスローテン フェンノートシャップ 医薬製剤
WO2013102921A2 (en) * 2011-11-17 2013-07-11 Sanzyme Limited Hcg - newer treatment modality for type 2 diabetes mellitus (t2dm)
CN103288950A (zh) * 2012-12-28 2013-09-11 青岛九龙生物医药有限公司 改进柱分离工序洗涤液和洗脱液配比去除杂质的方法
CN104101656A (zh) * 2013-04-01 2014-10-15 上海天伟生物制药有限公司 一种***的纯度测定方法
US20150065426A1 (en) * 2013-08-27 2015-03-05 Professional Compounding Centers Of America Testosterone Booster Transdermal Compositions
CN105968185A (zh) * 2016-07-20 2016-09-28 宁波人健药业集团股份有限公司 一种绒促性素纯化方法
CN111233999B (zh) * 2020-03-21 2024-02-23 上海浦东明炎生物技术有限公司 一种从人尿中提取人绒毛膜***的方法
CN113398251B (zh) * 2021-07-30 2022-08-05 宁波人健药业集团股份有限公司 一种重组人绒毛膜***冻干粉针剂及其制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE148171T1 (de) * 1989-02-21 1997-02-15 Univ Washington Modifizierte formen von fortpflanzungshormonen
IT1250075B (it) * 1991-12-18 1995-03-30 Serono Cesare Ist Ricerca Composizioni farmaceutiche contenenti gonadotropine.
IT1254370B (it) * 1992-05-22 1995-09-14 Sorin Biomedica Spa Procedimento per la purificazione di proteine da sistemi cellulari.
UA61053C2 (en) 1995-03-21 2003-11-17 Applied Research Systems Stable liquid pharmaceutical compositions, method for its production and delivery form
US6193972B1 (en) * 1996-02-20 2001-02-27 Applied Research Systems Ars Holding N.V. Hybrid heterodimeric protein hormone
IT1287138B1 (it) * 1996-11-07 1998-08-04 Ibsa Inst Biochimique Sa Procedimento per la separazione e purificazione di fsh e lh
AU8142198A (en) 1997-06-12 1998-12-30 Regents Of The University Of California, The A transcription factor coactivator protein, p/cip
CA2289665C (en) * 1997-06-13 2005-08-09 Genentech, Inc. Protein recovery by chromatography followed by filtration upon a charged layer
US6583109B1 (en) * 1997-06-24 2003-06-24 Robert C. Gallo Therapeutic polypeptides from β-hCG and derivatives
ME00296B (me) * 2000-02-22 2011-05-10 Applied Res Systems Ars Holding N V PROCES PREČIŠĆAVANJA hCG I REKOMBINANTNOG hCG PREČIŠĆENOG TOM METODOM

Also Published As

Publication number Publication date
CA2399020A1 (en) 2001-08-30
CN1404485A (zh) 2003-03-19
BR0108556A (pt) 2003-01-28
PL357508A1 (en) 2004-07-26
NO20023985L (no) 2002-08-21
EP1257564A1 (en) 2002-11-20
JP4588960B2 (ja) 2010-12-01
EE200200469A (et) 2004-04-15
BG65807B1 (bg) 2009-12-31
HU228935B1 (en) 2013-06-28
ZA200206109B (en) 2003-07-31
EA006605B1 (ru) 2006-02-24
AU2680401A (en) 2001-09-03
SK12062002A3 (sk) 2002-12-03
US20030104553A1 (en) 2003-06-05
HUP0204231A3 (en) 2005-09-28
MEP38908A (en) 2011-02-10
KR20030001359A (ko) 2003-01-06
UA78488C2 (en) 2007-04-10
CN100482679C (zh) 2009-04-29
CZ20022855A3 (cs) 2002-11-13
IL151308A0 (en) 2003-04-10
DK1257564T3 (da) 2008-10-06
SK287146B6 (sk) 2010-01-07
NO20023985D0 (no) 2002-08-21
HRP20020650A2 (en) 2004-12-31
HK1052016A1 (en) 2003-08-29
EA200200892A1 (ru) 2003-02-27
AU2006200059A1 (en) 2006-02-02
IL151308A (en) 2009-11-18
RS50741B (sr) 2010-08-31
ME00296B (me) 2011-05-10
CY1108460T1 (el) 2014-04-09
ES2307585T3 (es) 2008-12-01
CZ303144B6 (cs) 2012-05-02
ATE406378T1 (de) 2008-09-15
US7297777B2 (en) 2007-11-20
UA86938C2 (uk) 2009-06-10
EP1752466A3 (en) 2012-10-10
PT1257564E (pt) 2008-09-10
WO2001062773A1 (en) 2001-08-30
US20070299001A1 (en) 2007-12-27
MXPA02007871A (es) 2003-02-10
BRPI0108556B8 (pt) 2021-05-25
JP2003524015A (ja) 2003-08-12
YU60202A (sh) 2005-09-19
DE60135541D1 (de) 2008-10-09
HRP20020650B1 (en) 2011-02-28
HUP0204231A2 (hu) 2003-03-28
AU783320B2 (en) 2005-10-13
PL205149B1 (pl) 2010-03-31
BG107000A (en) 2003-04-30
EP1752466A2 (en) 2007-02-14
BRPI0108556B1 (pt) 2015-04-14
EP1257564B1 (en) 2008-08-27
KR100806911B1 (ko) 2008-02-22
SI1257564T1 (sl) 2008-12-31
HU1300063D0 (hu) 2003-03-28
NO328694B1 (no) 2010-04-26

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