EA201891024A1 - Соединения-ингибиторы tank-связывающей киназы - Google Patents

Соединения-ингибиторы tank-связывающей киназы

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Publication number
EA201891024A1
EA201891024A1 EA201891024A EA201891024A EA201891024A1 EA 201891024 A1 EA201891024 A1 EA 201891024A1 EA 201891024 A EA201891024 A EA 201891024A EA 201891024 A EA201891024 A EA 201891024A EA 201891024 A1 EA201891024 A1 EA 201891024A1
Authority
EA
Eurasian Patent Office
Prior art keywords
tank
kinase inhibitor
inhibitor compounds
binding kinase
binding
Prior art date
Application number
EA201891024A
Other languages
English (en)
Inventor
Чжиминь Ду
Дэвид ДОРНАН
Хуан А. Герреро
Джошуа А. Каплан
Джон Э. Нокс
Деван Надутхамби
Бартон В. Филлипс
Сюзанна И. Стинсон
Чандрасекар Венкатарамани
Пейюань Ван
Уильям Дж. Уоткинс
Original Assignee
Джилид Сайэнс, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Джилид Сайэнс, Инк. filed Critical Джилид Сайэнс, Инк.
Publication of EA201891024A1 publication Critical patent/EA201891024A1/ru

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    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
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Abstract

Описаны соединения, имеющие следующую формулу (I), и способы их применения и получения.
EA201891024A 2015-12-17 2016-12-15 Соединения-ингибиторы tank-связывающей киназы EA201891024A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562268846P 2015-12-17 2015-12-17
US201662425396P 2016-11-22 2016-11-22
PCT/US2016/067022 WO2017106556A1 (en) 2015-12-17 2016-12-15 Tank-binding kinase inhibitor compounds

Publications (1)

Publication Number Publication Date
EA201891024A1 true EA201891024A1 (ru) 2018-12-28

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Family Applications (1)

Application Number Title Priority Date Filing Date
EA201891024A EA201891024A1 (ru) 2015-12-17 2016-12-15 Соединения-ингибиторы tank-связывающей киназы

Country Status (24)

Country Link
US (1) US10316049B2 (ru)
EP (1) EP3394044A1 (ru)
JP (1) JP2019500368A (ru)
KR (1) KR20180094976A (ru)
CN (1) CN108430993A (ru)
AU (1) AU2016370916A1 (ru)
BR (1) BR112017002594A2 (ru)
CA (2) CA3006772A1 (ru)
CL (1) CL2018001586A1 (ru)
CO (1) CO2018006051A2 (ru)
CR (1) CR20180320A (ru)
CU (1) CU20180059A7 (ru)
DO (1) DOP2018000147A (ru)
EA (1) EA201891024A1 (ru)
EC (1) ECSP18044917A (ru)
IL (1) IL259719A (ru)
MA (1) MA44112A (ru)
MX (1) MX2018007421A (ru)
PE (1) PE20181073A1 (ru)
PH (1) PH12018501151A1 (ru)
SG (1) SG11201804294WA (ru)
TW (1) TWI639427B (ru)
UY (1) UY37036A (ru)
WO (1) WO2017106556A1 (ru)

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