ES2568899T3
(es)
|
1999-04-09 |
2016-05-05 |
Kyowa Hakko Kirin Co., Ltd. |
Procedimiento para controlar la actividad de una molécula inmunofuncional
|
US6946292B2
(en)
|
2000-10-06 |
2005-09-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
US8093357B2
(en)
|
2002-03-01 |
2012-01-10 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
US7317091B2
(en)
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
US8968730B2
(en)
|
2002-08-14 |
2015-03-03 |
Macrogenics Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US8946387B2
(en)
|
2002-08-14 |
2015-02-03 |
Macrogenics, Inc. |
FcγRIIB specific antibodies and methods of use thereof
|
US7355008B2
(en)
|
2003-01-09 |
2008-04-08 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
US7960512B2
(en)
|
2003-01-09 |
2011-06-14 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
US8388955B2
(en)
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
TWI353991B
(en)
|
2003-05-06 |
2011-12-11 |
Syntonix Pharmaceuticals Inc |
Immunoglobulin chimeric monomer-dimer hybrids
|
AU2004266159A1
(en)
|
2003-08-22 |
2005-03-03 |
Biogen Idec Ma Inc. |
Improved antibodies having altered effector function and methods for making the same
|
US8101720B2
(en)
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
EP2385069A3
(en)
|
2003-11-12 |
2012-05-30 |
Biogen Idec MA Inc. |
Neonatal Fc rReceptor (FcRn)- binding polypeptide variants, dimeric Fc binding proteins and methods related thereto
|
WO2005110474A2
(en)
|
2004-05-10 |
2005-11-24 |
Macrogenics, Inc. |
HUMANIZED FcϜRIIB SPECIFIC ANTIBODIES AND METHODS OF USE THEREOF
|
KR100545720B1
(ko)
*
|
2004-05-31 |
2006-01-24 |
메덱스젠 주식회사 |
당화된 면역글로불린 및 이를 포함하는 면역접합체
|
WO2006085967A2
(en)
*
|
2004-07-09 |
2006-08-17 |
Xencor, Inc. |
OPTIMIZED ANTI-CD20 MONOCONAL ANTIBODIES HAVING Fc VARIANTS
|
WO2006019447A1
(en)
*
|
2004-07-15 |
2006-02-23 |
Xencor, Inc. |
Optimized fc variants
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
US8647625B2
(en)
|
2004-07-26 |
2014-02-11 |
Biogen Idec Ma Inc. |
Anti-CD154 antibodies
|
WO2006020114A2
(en)
*
|
2004-08-04 |
2006-02-23 |
Applied Molecular Evolution, Inc. |
Variant fc regions
|
JP2008510008A
(ja)
|
2004-08-16 |
2008-04-03 |
メディミューン,インコーポレーテッド |
抗体依存性細胞性細胞傷害活性が増強されたインテグリンアンタゴニスト
|
US7632497B2
(en)
|
2004-11-10 |
2009-12-15 |
Macrogenics, Inc. |
Engineering Fc Antibody regions to confer effector function
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
EP2332985A3
(en)
|
2004-11-12 |
2012-01-25 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US8802820B2
(en)
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
CA2602663A1
(en)
*
|
2005-03-31 |
2006-10-05 |
Xencor, Inc. |
Fc variants with optimized properties
|
US9284375B2
(en)
|
2005-04-15 |
2016-03-15 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
US9889197B2
(en)
|
2005-04-15 |
2018-02-13 |
Macrogenics, Inc. |
Covalently-associated diabody complexes that possess charged coil domains and that are capable of enhanced binding to serum albumin
|
US9963510B2
(en)
|
2005-04-15 |
2018-05-08 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
ES2707152T3
(es)
|
2005-04-15 |
2019-04-02 |
Macrogenics Inc |
Diacuerpos covalentes y usos de los mismos
|
US11254748B2
(en)
|
2005-04-15 |
2022-02-22 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
CA2606102C
(en)
|
2005-04-26 |
2014-09-30 |
Medimmune, Inc. |
Modulation of antibody effector function by hinge domain engineering
|
CA2605697A1
(en)
*
|
2005-04-26 |
2006-11-02 |
Bioren, Inc. |
Method of producing human igg antibodies with enhanced effector functions
|
EP1899477A4
(en)
|
2005-07-01 |
2010-01-20 |
Medimmune Inc |
INTEGRATED APPROACH FOR GENERATING MULTIDOMAIN PROTEIN THERAPEUTIC APPLICATIONS
|
SI1919503T1
(sl)
|
2005-08-10 |
2015-02-27 |
Macrogenics, Inc. |
Identifikacija in inĺ˝eniring protiteles z variantnimi fc regijami in postopki za njih uporabo
|
EP1931709B1
(en)
|
2005-10-03 |
2016-12-07 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
CA2625998C
(en)
|
2005-10-06 |
2015-12-01 |
Xencor, Inc. |
Optimized anti-cd30 antibodies
|
JP2009511067A
(ja)
|
2005-10-14 |
2009-03-19 |
メディミューン,エルエルシー |
抗体ライブラリーの細胞提示
|
MY149159A
(en)
|
2005-11-15 |
2013-07-31 |
Hoffmann La Roche |
Method for treating joint damage
|
FR2894983B1
(fr)
*
|
2005-12-16 |
2012-08-17 |
Lab Francais Du Fractionnement |
Test de caracterisation des anticorps.
|
TW200745163A
(en)
*
|
2006-02-17 |
2007-12-16 |
Syntonix Pharmaceuticals Inc |
Peptides that block the binding of IgG to FcRn
|
JP5624276B2
(ja)
|
2006-03-31 |
2014-11-12 |
中外製薬株式会社 |
抗体の血中動態を制御する方法
|
US20100080794A1
(en)
*
|
2006-04-14 |
2010-04-01 |
Takashi Tsuji |
Mutant polypeptide having effector function
|
LT2029173T
(lt)
|
2006-06-26 |
2016-11-10 |
Macrogenics, Inc. |
Fc riib specifiniai antikūnai ir jų panaudojimo būdai
|
EP2032159B1
(en)
|
2006-06-26 |
2015-01-07 |
MacroGenics, Inc. |
Combination of fcgammariib antibodies and cd20-specific antibodies and methods of use thereof
|
WO2008008482A2
(en)
*
|
2006-07-13 |
2008-01-17 |
Genentech, Inc. |
Altered br3-binding polypeptides
|
WO2008022152A2
(en)
|
2006-08-14 |
2008-02-21 |
Xencor, Inc. |
Optimized antibodies that target cd19
|
WO2008032833A1
(fr)
*
|
2006-09-14 |
2008-03-20 |
Medical & Biological Laboratories Co., Ltd. |
Anticorps présentant une activité adcc accrue et son procédé de production
|
AU2007299843B2
(en)
|
2006-09-18 |
2012-03-08 |
Xencor, Inc |
Optimized antibodies that target HM1.24
|
US8652466B2
(en)
|
2006-12-08 |
2014-02-18 |
Macrogenics, Inc. |
Methods for the treatment of disease using immunoglobulins having Fc regions with altered affinities for FcγRactivating and FcγRinhibiting
|
EP2120915B1
(en)
|
2007-01-22 |
2011-09-28 |
Genentech, Inc. |
Polyelectrolyte precipitation and purification of antibodies
|
KR101578940B1
(ko)
*
|
2007-01-24 |
2015-12-18 |
교와 핫꼬 기린 가부시키가이샤 |
이펙터 활성이 증강된 유전자 재조합 항체 조성물
|
US20080279851A1
(en)
|
2007-05-07 |
2008-11-13 |
Medlmmune, Llc |
Anti-icos antibodies and their use in treatment of oncology, transplantation and autoimmune disease
|
JP2010535032A
(ja)
|
2007-07-31 |
2010-11-18 |
メディミューン,エルエルシー |
多重特異性エピトープ結合性タンパク質およびその用途
|
JP5334319B2
(ja)
|
2007-09-26 |
2013-11-06 |
中外製薬株式会社 |
Cdrのアミノ酸置換により抗体の等電点を改変する方法
|
JP5427348B2
(ja)
*
|
2007-10-12 |
2014-02-26 |
株式会社医学生物学研究所 |
エフェクター機能が向上した抗体
|
US20120047586A9
(en)
|
2007-10-24 |
2012-02-23 |
Otsuka Chemical Co., Ltd |
Polypeptide having enhanced effector function
|
WO2009117030A2
(en)
|
2007-12-19 |
2009-09-24 |
Macrogenics, Inc. |
Improved compositions for the prevention and treatment of smallpox
|
DK2245064T3
(da)
|
2007-12-21 |
2014-10-27 |
Medimmune Ltd |
BINDINGSELEMENTER TIL INTERLEUKIN-4-RECEPTOR-ALFA (IL-4Ralfa)
|
US8092804B2
(en)
|
2007-12-21 |
2012-01-10 |
Medimmune Limited |
Binding members for interleukin-4 receptor alpha (IL-4Rα)-173
|
SI2235059T1
(sl)
|
2007-12-26 |
2015-06-30 |
Xencor, Inc. |
Fc variante s spremenjeno vezjo na fcrn
|
CN102083460A
(zh)
|
2008-01-18 |
2011-06-01 |
米迪缪尼有限公司 |
用于位点特异性偶联的半胱氨酸工程化抗体
|
CN106349390B
(zh)
|
2008-04-02 |
2019-12-10 |
宏观基因有限公司 |
Bcr-复合体-特异性抗体和其使用方法
|
BRPI0906309A2
(pt)
|
2008-04-02 |
2020-05-26 |
Macrogenics, Inc |
Imunoglobulina, anticorpo, uso do anticorpo e composição farmacêutica
|
KR20220162801A
(ko)
|
2008-04-11 |
2022-12-08 |
추가이 세이야쿠 가부시키가이샤 |
복수 분자의 항원에 반복 결합하는 항원 결합 분자
|
WO2010001908A1
(ja)
|
2008-06-30 |
2010-01-07 |
協和発酵キリン株式会社 |
抗cd27抗体
|
AR073295A1
(es)
|
2008-09-16 |
2010-10-28 |
Genentech Inc |
Metodos para tratar la esclerosis multiple progresiva. articulo de fabricacion.
|
EP2358392B1
(en)
|
2008-11-12 |
2019-01-09 |
MedImmune, LLC |
Antibody formulation
|
WO2010075249A2
(en)
|
2008-12-22 |
2010-07-01 |
Genentech, Inc. |
A method for treating rheumatoid arthritis with b-cell antagonists
|
ES2602459T3
(es)
|
2008-12-26 |
2017-02-21 |
Kyowa Hakko Kirin Co., Ltd. |
Anticuerpo anti-CD4
|
AU2009334498A1
(en)
|
2008-12-31 |
2011-07-21 |
Biogen Idec Ma Inc. |
Anti-lymphotoxin antibodies
|
US20120213705A1
(en)
|
2009-06-22 |
2012-08-23 |
Medimmune, Llc |
ENGINEERED Fc REGIONS FOR SITE-SPECIFIC CONJUGATION
|
US20120263701A1
(en)
|
2009-08-24 |
2012-10-18 |
Volker Schellenberger |
Coagulation factor vii compositions and methods of making and using same
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
CA2776385C
(en)
|
2009-10-07 |
2019-04-09 |
Macrogenics, Inc. |
Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use
|
CN106399276B
(zh)
|
2009-11-02 |
2021-08-10 |
华盛顿大学 |
治疗性核酸酶组合物和方法
|
AU2010339863B2
(en)
*
|
2009-12-21 |
2014-07-17 |
Regeneron Pharmaceuticals, Inc. |
Humanized FcyR mice
|
US8362210B2
(en)
|
2010-01-19 |
2013-01-29 |
Xencor, Inc. |
Antibody variants with enhanced complement activity
|
MX341687B
(es)
|
2010-02-10 |
2016-08-30 |
Immunogen Inc |
"anticuerpos cd20 y su utilización".
|
ES2602971T3
(es)
|
2010-03-02 |
2017-02-23 |
Kyowa Hakko Kirin Co., Ltd. |
Composición de anticuerpo modificado
|
PH12018501083A1
(en)
|
2010-03-04 |
2019-02-18 |
Macrogenics Inc |
Antibodies reactive with b7-h3, immunologically active fragments thereof and uses thereof
|
US8802091B2
(en)
|
2010-03-04 |
2014-08-12 |
Macrogenics, Inc. |
Antibodies reactive with B7-H3 and uses thereof
|
TWI667257B
(zh)
|
2010-03-30 |
2019-08-01 |
中外製藥股份有限公司 |
促進抗原消失之具有經修飾的FcRn親和力之抗體
|
DK2591099T3
(da)
|
2010-07-09 |
2021-02-15 |
Bioverativ Therapeutics Inc |
Kimære koagulationsfaktorer
|
US20130287763A1
(en)
*
|
2010-07-28 |
2013-10-31 |
Merck Sharp & Dohme Corp. |
Combination therapy for treating cancer comprising an igf-1r inhibitor and an akt inhibitor
|
BR112013002535A2
(pt)
|
2010-08-03 |
2019-09-24 |
Hoffmann La Roche |
biomarcadores de leucemia linfocítica crônica (cll)
|
US20130177555A1
(en)
|
2010-08-13 |
2013-07-11 |
Medimmune Limited |
Monomeric Polypeptides Comprising Variant FC Regions And Methods Of Use
|
WO2012022734A2
(en)
|
2010-08-16 |
2012-02-23 |
Medimmune Limited |
Anti-icam-1 antibodies and methods of use
|
EP3351559A3
(en)
|
2010-11-08 |
2018-10-31 |
F. Hoffmann-La Roche AG |
Subcutaneously administered anti-il-6 receptor antibody
|
EP2647706B1
(en)
|
2010-11-30 |
2023-05-17 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly
|
EP2679681B2
(en)
|
2011-02-25 |
2023-11-15 |
Chugai Seiyaku Kabushiki Kaisha |
FcgammaRIIB-specific FC antibody
|
CA2830254C
(en)
*
|
2011-03-16 |
2019-09-10 |
Amgen Inc. |
Fc variants
|
ES2876421T3
(es)
|
2011-04-13 |
2021-11-12 |
Bristol Myers Squibb Co |
Proteínas de fusión Fc que comprenden enlazadores o disposiciones nuevos
|
CA2832389A1
(en)
*
|
2011-04-20 |
2012-10-26 |
Genmab A/S |
Bispecific antibodies against her2 and cd3
|
KR102596953B1
(ko)
|
2011-04-29 |
2023-11-02 |
유니버시티 오브 워싱톤 스루 이츠 센터 포 커머셜리제이션 |
치료적 뉴클레아제 조성물 및 방법
|
EA201391753A1
(ru)
|
2011-05-21 |
2014-08-29 |
Макродженикс, Инк. |
Домены, связывающиеся с деиммунизованной сывороткой, и их применение для увеличения времени полужизни в сыворотке
|
EP2717898B1
(en)
|
2011-06-10 |
2018-12-19 |
Bioverativ Therapeutics Inc. |
Pro-coagulant compounds and methods of use thereof
|
KR20140033152A
(ko)
|
2011-06-20 |
2014-03-17 |
교와 핫꼬 기린 가부시키가이샤 |
항erbB3 항체
|
UA117901C2
(uk)
*
|
2011-07-06 |
2018-10-25 |
Ґенмаб Б.В. |
Спосіб посилення ефекторної функції вихідного поліпептиду, його варіанти та їх застосування
|
KR20200120743A
(ko)
*
|
2011-07-06 |
2020-10-21 |
젠맵 비. 브이 |
항체 변이체 및 그의 용도
|
US9738707B2
(en)
|
2011-07-15 |
2017-08-22 |
Biogen Ma Inc. |
Heterodimeric Fc regions, binding molecules comprising same, and methods relating thereto
|
UY34317A
(es)
|
2011-09-12 |
2013-02-28 |
Genzyme Corp |
Anticuerpo antireceptor de célula T (alfa)/ß
|
US20130108641A1
(en)
|
2011-09-14 |
2013-05-02 |
Sanofi |
Anti-gitr antibodies
|
US20140335089A1
(en)
|
2011-09-30 |
2014-11-13 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule for promoting elimination of antigens
|
CN110655578A
(zh)
|
2011-09-30 |
2020-01-07 |
中外制药株式会社 |
诱导针对靶抗原的免疫应答的抗原结合分子
|
WO2013047748A1
(ja)
|
2011-09-30 |
2013-04-04 |
中外製薬株式会社 |
複数の生理活性を有する抗原の消失を促進する抗原結合分子
|
TW201817744A
(zh)
*
|
2011-09-30 |
2018-05-16 |
日商中外製藥股份有限公司 |
具有促進抗原清除之FcRn結合域的治療性抗原結合分子
|
RS55822B1
(sr)
|
2011-09-30 |
2017-08-31 |
Dana-Farber Cancer Institute Inc |
Terapijski peptidi
|
CA2854806A1
(en)
|
2011-11-07 |
2013-05-16 |
Medimmune, Llc |
Multispecific and multivalent binding proteins and uses thereof
|
WO2013081143A1
(ja)
|
2011-11-30 |
2013-06-06 |
中外製薬株式会社 |
免疫複合体を形成する細胞内への運搬体(キャリア)を含む医薬
|
JP6483442B2
(ja)
|
2011-12-05 |
2019-03-13 |
エックス−ボディ インコーポレイテッド |
Pdgf受容体ベータ結合ポリペプチド
|
CA3111357A1
(en)
|
2011-12-23 |
2013-06-27 |
Pfizer Inc. |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
TWI593705B
(zh)
|
2011-12-28 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Humanized anti-epiregulin antibody and cancer therapeutic agent containing the antibody as an active ingredient
|
KR102212098B1
(ko)
|
2012-01-12 |
2021-02-03 |
바이오버라티브 테라퓨틱스 인크. |
키메라 인자 viii 폴리펩티드들과 이의 용도
|
US10370430B2
(en)
|
2012-02-15 |
2019-08-06 |
Bioverativ Therapeutics Inc. |
Recombinant factor VIII proteins
|
SG11201404885RA
(en)
|
2012-02-15 |
2014-09-26 |
Amunix Operating Inc |
Factor viii compositions and methods of making and using same
|
SG10201702396QA
(en)
|
2012-03-28 |
2017-04-27 |
Sanofi Sa |
Antibodies to bradykinin b1 receptor ligands
|
EP2832856A4
(en)
|
2012-03-29 |
2016-01-27 |
Chugai Pharmaceutical Co Ltd |
ANTI-LAMP5 ANTIBODIES AND USE THEREOF
|
MX2014013637A
(es)
|
2012-05-07 |
2015-02-05 |
Sanofi Sa |
Metodos para prevencion de la formacion de biopelicula.
|
WO2013175276A1
(en)
|
2012-05-23 |
2013-11-28 |
Argen-X B.V |
Il-6 binding molecules
|
CA2874721A1
(en)
|
2012-05-30 |
2013-12-05 |
Tomoyuki Igawa |
Target tissue-specific antigen-binding molecule
|
DK2857419T3
(da)
|
2012-05-30 |
2021-03-29 |
Chugai Pharmaceutical Co Ltd |
Antigen-bindende molekyle til eliminering af aggregerede antigener
|
CA2875247A1
(en)
|
2012-06-08 |
2013-12-12 |
Biogen Idec Ma Inc. |
Chimeric clotting factors
|
AU2013270682A1
(en)
|
2012-06-08 |
2014-12-11 |
Biogen Ma Inc. |
Procoagulant compounds
|
EP3632462A1
(en)
*
|
2012-07-06 |
2020-04-08 |
Genmab B.V. |
Dimeric protein with triple mutations
|
EP2870250B2
(en)
|
2012-07-06 |
2022-06-29 |
Bioverativ Therapeutics Inc. |
Cell line expressing single chain factor viii polypeptides and uses thereof
|
CA2877848C
(en)
|
2012-07-06 |
2021-11-02 |
St. Marianna University School Of Medicine |
Therapeutic method and medicament for htlv-1 associated myelopathy (ham)
|
EP2869845B1
(en)
|
2012-07-06 |
2019-08-28 |
Genmab B.V. |
Dimeric protein with triple mutations
|
SG11201500045RA
(en)
|
2012-07-11 |
2015-02-27 |
Amunix Operating Inc |
Factor viii complex with xten and von willebrand factor protein, and uses thereof
|
BR112015001955A2
(pt)
|
2012-08-24 |
2017-11-07 |
Chugai Pharmaceutical Co Ltd |
variante de região fc específica de fcgamariib
|
US9790268B2
(en)
|
2012-09-12 |
2017-10-17 |
Genzyme Corporation |
Fc containing polypeptides with altered glycosylation and reduced effector function
|
HRP20230623T1
(hr)
|
2012-09-12 |
2023-09-29 |
Genzyme Corporation |
Polipeptidi koji sadrže fc domenu s promijenjenom glikozilacijom i smanjenom efektorskom funkcijom
|
PT2925350T
(pt)
|
2012-12-03 |
2019-03-25 |
Bristol Myers Squibb Co |
Melhoria da atividade anticancerosa de proteínas de fusão de fc imunomoduladoras
|
WO2014088040A1
(ja)
|
2012-12-06 |
2014-06-12 |
国立大学法人 金沢大学 |
中皮腫の治療方法
|
EP3557260B1
(en)
|
2012-12-21 |
2022-05-18 |
Chugai Seiyaku Kabushiki Kaisha |
Gpc3-targeting drug which is administered to patient responsive to gpc3-targeting drug therapy
|
TWI693073B
(zh)
|
2012-12-21 |
2020-05-11 |
日商中外製藥股份有限公司 |
對gpc3標的治療劑療法為有效之患者投與的gpc3標的治療劑
|
AU2013372331A1
(en)
*
|
2013-01-10 |
2015-07-23 |
Genmab B.V. |
Human IgG1 Fc region variants and uses thereof
|
WO2014126871A1
(en)
|
2013-02-12 |
2014-08-21 |
Bristol-Myers Squibb Company |
Tangential flow filtration based protein refolding methods
|
EP3617220B1
(en)
|
2013-02-12 |
2021-03-24 |
Bristol-Myers Squibb Company |
High ph protein refolding methods
|
DK3889173T3
(da)
|
2013-02-15 |
2023-10-09 |
Bioverativ Therapeutics Inc |
Optimeret faktor viii-gen
|
US9487587B2
(en)
|
2013-03-05 |
2016-11-08 |
Macrogenics, Inc. |
Bispecific molecules that are immunoreactive with immune effector cells of a companion animal that express an activating receptor and cells that express B7-H3 and uses thereof
|
EP4063389A3
(en)
|
2013-03-11 |
2022-12-28 |
Genzyme Corporation |
Site-specific antibody-drug conjugation through glycoengineering
|
AU2014244286B2
(en)
|
2013-03-14 |
2018-11-08 |
Duke University |
Bispecific molecules that are immunoreactive with immune effector cells that express an activating receptor
|
EP2968498A4
(en)
|
2013-03-15 |
2016-09-07 |
Biogen Ma Inc |
PREPARATIONS CONTAINING FACTOR IX POLYPEPTIDE
|
US10745483B2
(en)
|
2013-03-15 |
2020-08-18 |
Dana-Farber Cancer Institute, Inc. |
Therapeutic peptides
|
WO2014163101A1
(ja)
|
2013-04-02 |
2014-10-09 |
中外製薬株式会社 |
Fc領域改変体
|
CN105517571A
(zh)
|
2013-06-24 |
2016-04-20 |
中外制药株式会社 |
含有人源化抗上皮调节蛋白抗体作为有效成分的腺癌以外的非小细胞肺癌的治疗药
|
EP3875106A1
(en)
|
2013-08-08 |
2021-09-08 |
Bioverativ Therapeutics Inc. |
Purification of chimeric fviii molecules
|
US11384149B2
(en)
|
2013-08-09 |
2022-07-12 |
Macrogenics, Inc. |
Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof
|
UA116479C2
(uk)
|
2013-08-09 |
2018-03-26 |
Макродженікс, Інк. |
БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
|
EA033403B1
(ru)
|
2013-08-13 |
2019-10-31 |
Sanofi Sa |
Антитела к ингибитору активатора плазминогена 1 (pai-1) и пути их применения
|
TW201734054A
(zh)
|
2013-08-13 |
2017-10-01 |
賽諾菲公司 |
胞漿素原活化素抑制劑-1(pai-1)之抗體及其用途
|
US10548953B2
(en)
|
2013-08-14 |
2020-02-04 |
Bioverativ Therapeutics Inc. |
Factor VIII-XTEN fusions and uses thereof
|
EP2840091A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof
|
EP2839842A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
|
EP3903599A1
(en)
|
2013-09-25 |
2021-11-03 |
Bioverativ Therapeutics Inc. |
On-column viral inactivation methods
|
AU2014329609B2
(en)
|
2013-10-02 |
2019-09-12 |
Humabs Biomed Sa |
Neutralizing anti-influenza A antibodies and uses thereof
|
GEP20237496B
(en)
|
2013-10-18 |
2023-04-10 |
Deutsches Krebsforsch |
Labeled inhibitors of prostate specific membrane antigen (psma), their use as imaging agents and pharmaceutical agents for the treatment of prostate cancer
|
WO2015066550A1
(en)
|
2013-10-31 |
2015-05-07 |
Resolve Therapeutics, Llc |
Therapeutic nuclease-albumin fusions and methods
|
US10584147B2
(en)
|
2013-11-08 |
2020-03-10 |
Biovertiv Therapeutics Inc. |
Procoagulant fusion compound
|
EP3070168A4
(en)
|
2013-11-11 |
2017-06-28 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule containing modified antibody variable region
|
KR20220142539A
(ko)
|
2013-12-04 |
2022-10-21 |
추가이 세이야쿠 가부시키가이샤 |
화합물의 농도에 따라 항원 결합능이 변화되는 항원 결합 분자 및 그의 라이브러리
|
MX371187B
(es)
|
2013-12-06 |
2020-01-22 |
Dana Farber Cancer Inst Inc |
Péptidos terapéuticos.
|
US8986691B1
(en)
|
2014-07-15 |
2015-03-24 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
US8980273B1
(en)
|
2014-07-15 |
2015-03-17 |
Kymab Limited |
Method of treating atopic dermatitis or asthma using antibody to IL4RA
|
BR112016015512B1
(pt)
|
2014-01-10 |
2023-12-19 |
Bioverativ Therapeutics Inc |
Proteína quimérica, composição farmacêutica e seus usos
|
AU2015229009B2
(en)
|
2014-03-14 |
2019-08-22 |
Dana-Farber Cancer Institute, Inc. |
Vaccine compositions and methods for restoring NKG2D pathway function against cancers
|
US10995148B2
(en)
|
2014-03-19 |
2021-05-04 |
Genzyme Corporation |
Site-specific glycoengineering of targeting moieties
|
CN113150163A
(zh)
|
2014-03-21 |
2021-07-23 |
X博迪公司 |
双特异性抗原结合多肽
|
EP3141603A4
(en)
|
2014-05-08 |
2017-12-27 |
Chugai Seiyaku Kabushiki Kaisha |
Gpc3-targeted therapeutic agent for administration to patients for whom gpc3-targeted therapeutic agent therapy is effective
|
WO2015187835A2
(en)
|
2014-06-06 |
2015-12-10 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
EP3160478A4
(en)
|
2014-06-30 |
2018-05-16 |
Bioverativ Therapeutics Inc. |
Optimized factor ix gene
|
PE20170702A1
(es)
|
2014-09-26 |
2017-06-24 |
Bayer Pharma AG |
Derivados estabilizados de adrenomedulina y uso de los mismos
|
AU2015323860B2
(en)
|
2014-09-29 |
2021-05-27 |
Duke University |
Bispecific molecules comprising an HIV-1 envelope targeting arm
|
ES2838680T3
(es)
|
2014-10-09 |
2021-07-02 |
Genzyme Corp |
Conjugados de anticuerpo-fármaco glucomodificados
|
EA201700181A1
(ru)
|
2014-10-14 |
2017-09-29 |
Галозим, Инк. |
Композиции аденозиндеаминазы-2 (ада-2), их варианты и способы использования
|
US11154615B2
(en)
|
2014-11-11 |
2021-10-26 |
Chugai Seiyaku Kabushiki Kaisha |
Library of antigen-binding molecules including modified antibody variable region
|
BR112017010110A2
(pt)
|
2014-11-21 |
2018-01-30 |
Bristol-Myers Squibb Company |
anticorpos contra cd73 e usos do mesmo
|
SI3221346T1
(sl)
|
2014-11-21 |
2020-11-30 |
Bristol-Myers Squibb Company |
Protitelesa vsebujoča modificirana težko konstantna območja
|
MX2017007209A
(es)
|
2014-12-18 |
2017-08-28 |
Hoffmann La Roche |
Prueba y metodo para determinar anticuerpos de produccion de citotoxicidad dependiente del complemento (cdc).
|
KR20180054923A
(ko)
|
2014-12-19 |
2018-05-24 |
추가이 세이야쿠 가부시키가이샤 |
항-마이오스타틴 항체, 변이체 Fc 영역을 함유하는 폴리펩타이드, 및 사용 방법
|
UY36471A
(es)
|
2014-12-23 |
2016-06-30 |
Bristol Myers Squibb Company Una Corporación Del Estado De Delaware |
Anticuerpos contra el inmunorreceptor (tigit) de linfocitos t con dominios ig y motivos de inhibición del inmunorreceptor basados en tirosina (itim)
|
MX2017008978A
(es)
|
2015-02-05 |
2017-10-25 |
Chugai Pharmaceutical Co Ltd |
Anticuerpos que comprenden un dominio de union al antigeno dependiente de la concentracion ionica, variantes de la region fc, antiocuerpor de union a interleucina 8 (il-8) y usos de los mismos.
|
PE20180926A1
(es)
|
2015-05-29 |
2018-06-08 |
Bristol Myers Squibb Co |
Anticuerpos contra el miembro 4 de la superfamilia del receptor del factor de necrosis tumoral (ox40) y sus usos
|
AU2016301303B2
(en)
|
2015-08-03 |
2021-10-07 |
Bioverativ Therapeutics Inc. |
Factor IX fusion proteins and methods of making and using same
|
US20190022092A1
(en)
|
2015-09-15 |
2019-01-24 |
Acerta Pharma B.V. |
Therapeutic Combinations of a BTK Inhibitor and a GITR Binding Molecule, a 4-1BB Agonist, or an OX40 Agonist
|
KR20230079500A
(ko)
|
2015-09-18 |
2023-06-07 |
추가이 세이야쿠 가부시키가이샤 |
Il-8에 결합하는 항체 및 그의 사용
|
CA3005855A1
(en)
|
2015-11-19 |
2017-05-26 |
Bristol-Myers Squibb Company |
Antibodies against glucocorticoid-induced tumor necrosis factor receptor (gitr) and uses thereof
|
SG10201913278PA
(en)
|
2016-02-01 |
2020-02-27 |
Bioverativ Therapeutics Inc |
Optimized factor viii genes
|
AU2017228470A1
(en)
|
2016-03-04 |
2018-08-30 |
Bristol-Myers Squibb Company |
Combination therapy with anti-CD73 antibodies
|
TWI759287B
(zh)
|
2016-03-15 |
2022-04-01 |
日商中外製藥股份有限公司 |
使用pd-1軸結合拮抗劑和抗gpc3抗體治療癌症的方法
|
JP2019518713A
(ja)
|
2016-03-16 |
2019-07-04 |
メリマック ファーマシューティカルズ インコーポレーティッド |
癌療法のための改変trail
|
US10961311B2
(en)
|
2016-04-15 |
2021-03-30 |
Macrogenics, Inc. |
B7-H3 binding molecules, antibody drug conjugates thereof and methods of use thereof
|
KR102417687B1
(ko)
|
2016-05-09 |
2022-07-07 |
브리스톨-마이어스 스큅 컴퍼니 |
Tl1a 항체 및 그의 용도
|
AU2017290389A1
(en)
|
2016-07-01 |
2019-02-14 |
Resolve Therapeutics, Llc |
Optimized binuclease fusions and methods
|
JP7027401B2
(ja)
|
2016-07-14 |
2022-03-01 |
ブリストル-マイヤーズ スクイブ カンパニー |
Tim3に対する抗体およびその使用
|
JP7464389B2
(ja)
|
2016-08-02 |
2024-04-09 |
ビステラ, インコーポレイテッド |
操作されたポリペプチドおよびその使用
|
WO2018044970A1
(en)
|
2016-08-31 |
2018-03-08 |
University Of Rochester |
Human monoclonal antibodies to human endogenous retrovirus k envelope (herv-k) and uses thereof
|
TWI788307B
(zh)
|
2016-10-31 |
2023-01-01 |
美商艾歐凡斯生物治療公司 |
用於擴增腫瘤浸潤性淋巴細胞之工程化人造抗原呈現細胞
|
EP3545002A2
(en)
|
2016-11-23 |
2019-10-02 |
Bioverativ Therapeutics Inc. |
Mono- and bispecific antibodies binding to coagulation factor ix and coagulation factor x
|
TW201825119A
(zh)
|
2016-11-30 |
2018-07-16 |
日商協和醱酵麒麟有限公司 |
使用抗ccr4抗體及抗pd-1抗體治療癌症之方法
|
CN110520150A
(zh)
|
2016-12-02 |
2019-11-29 |
比奥维拉迪维治疗股份有限公司 |
使用嵌合凝血因子治疗血友病性关节病的方法
|
EP3548063A1
(en)
|
2016-12-02 |
2019-10-09 |
Bioverativ Therapeutics Inc. |
Methods of inducing immune tolerance to clotting factors
|
US20200121719A1
(en)
|
2017-01-06 |
2020-04-23 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes (tils) with tumor necrosis factor receptor superfamily (tnfrsf) agonists and therapeutic combinations of tils and tnfrsf agonists
|
CA3049165A1
(en)
|
2017-01-06 |
2018-07-12 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof
|
EP3574918A4
(en)
|
2017-01-24 |
2021-03-03 |
Kyowa Kirin Co., Ltd. |
THERAPEUTIC OR PROPHYLACTIC AND TREATMENT OR PREVENTION PROCEDURES FOR RADIATION DISEASE
|
CN110945021A
(zh)
*
|
2017-02-10 |
2020-03-31 |
根马布私人有限公司 |
多肽变体及其用途
|
WO2018151821A1
(en)
|
2017-02-17 |
2018-08-23 |
Bristol-Myers Squibb Company |
Antibodies to alpha-synuclein and uses thereof
|
CA3054778A1
(en)
|
2017-03-02 |
2018-09-07 |
Kyowa Kirin Co., Ltd. |
Preventive or therapeutic agent for htlv-1 associated myelopathy using low-dose of anti-ccr4 antibody
|
MX2019013202A
(es)
|
2017-05-10 |
2020-01-21 |
Iovance Biotherapeutics Inc |
Expansion de linfocitos de infiltracion de tumor a partir de tumores liquidos y usos terapeuticos de los mismos.
|
US11168129B2
(en)
|
2017-05-15 |
2021-11-09 |
University Of Rochester |
Broadly neutralizing anti-influenza human monoclonal antibody and uses thereof
|
EP3630833A1
(en)
|
2017-05-25 |
2020-04-08 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
MX2020001593A
(es)
|
2017-08-09 |
2020-07-13 |
Bioverativ Therapeutics Inc |
Moleculas de acido nucleico y usos de las mismas.
|
AU2018321359B2
(en)
|
2017-08-22 |
2023-11-30 |
Sanabio, Llc |
Soluble interferon receptors and uses thereof
|
WO2019059411A1
(en)
|
2017-09-20 |
2019-03-28 |
Chugai Seiyaku Kabushiki Kaisha |
DOSAGE FOR POLYTHERAPY USING PD-1 AXIS BINDING ANTAGONISTS AND GPC3 TARGETING AGENT
|
EP3694552A1
(en)
|
2017-10-10 |
2020-08-19 |
Tilos Therapeutics, Inc. |
Anti-lap antibodies and uses thereof
|
JP2021503885A
(ja)
|
2017-11-22 |
2021-02-15 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
末梢血からの末梢血リンパ球(pbl)の拡大培養
|
EP3720963A4
(en)
|
2017-12-05 |
2021-12-08 |
Chugai Seiyaku Kabushiki Kaisha |
ANTIGEN BINDING MOLECULE INCLUDING A VARIABLE REGION OF MODIFIED ANTIBODIES BINDING TO CD3 AND CD137
|
CA3085765A1
(en)
|
2017-12-15 |
2019-06-20 |
Iovance Biotherapeutics, Inc. |
Systems and methods for determining the beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof and beneficial administration of tumor infiltrating lymphocytes, and methods of use thereof
|
US20210087267A1
(en)
|
2017-12-20 |
2021-03-25 |
Alexion Pharmaceuticals, Inc. |
Liquid formulations of anti-cd200 antibodies
|
WO2019126536A1
(en)
|
2017-12-20 |
2019-06-27 |
Alexion Pharmaceuticals Inc. |
Humanized anti-cd200 antibodies and uses thereof
|
KR20200108870A
(ko)
|
2018-01-12 |
2020-09-21 |
브리스톨-마이어스 스큅 컴퍼니 |
Tim3에 대한 항체 및 그의 용도
|
MX2020008152A
(es)
|
2018-02-01 |
2020-11-24 |
Bioverativ Therapeutics Inc |
Uso de vectores lentivirales que expresan el factor viii.
|
JP2021512962A
(ja)
|
2018-02-13 |
2021-05-20 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
アデノシンa2a受容体アンタゴニストによる腫瘍浸潤性リンパ球(til)の拡大培養並びにtil及びアデノシンa2a受容体アンタゴニストの治療的組み合わせ
|
JP2018138022A
(ja)
*
|
2018-02-23 |
2018-09-06 |
ゲンマブ ビー.ブイ. |
ヒトIgG1 Fc領域変異体およびその使用
|
AU2019239747A1
(en)
|
2018-03-21 |
2020-10-08 |
Bristol-Myers Squibb Company |
Antibodies binding to VISTA at acidic pH
|
AU2019236865A1
(en)
|
2018-03-23 |
2020-10-01 |
Bristol-Myers Squibb Company |
Antibodies against MICA and/or MICB and uses thereof
|
CA3094112A1
(en)
|
2018-03-28 |
2019-10-03 |
Bristol-Myers Squibb Company |
Interleukin-2/interleukin-2 receptor alpha fusion proteins and methods of use
|
KR20200139219A
(ko)
|
2018-04-02 |
2020-12-11 |
브리스톨-마이어스 스큅 컴퍼니 |
항-trem-1 항체 및 이의 용도
|
JP7402541B2
(ja)
|
2018-05-03 |
2023-12-21 |
ユニバーシティ オブ ロチェスター |
抗インフルエンザノイラミニダーゼモノクローナル抗体およびその使用
|
SG11202010767SA
(en)
|
2018-05-18 |
2020-11-27 |
Bioverativ Therapeutics Inc |
Methods of treating hemophilia a
|
US20210238289A1
(en)
|
2018-06-04 |
2021-08-05 |
Biogen Ma Inc. |
Anti-vla-4 antibodies having reduced effector function
|
CN114903978A
(zh)
|
2018-07-03 |
2022-08-16 |
百时美施贵宝公司 |
Fgf-21配制品
|
CN113056483A
(zh)
|
2018-07-09 |
2021-06-29 |
戊瑞治疗有限公司 |
结合到ilt4的抗体
|
CN112638948A
(zh)
|
2018-07-11 |
2021-04-09 |
戊瑞治疗有限公司 |
在酸性pH下结合至VISTA的抗体
|
WO2020033863A1
(en)
|
2018-08-09 |
2020-02-13 |
Bioverativ Therapeutics Inc. |
Nucleic acid molecules and uses thereof for non-viral gene therapy
|
TW202031273A
(zh)
|
2018-08-31 |
2020-09-01 |
美商艾歐凡斯生物治療公司 |
抗pd-1抗體難治療性之非小細胞肺癌(nsclc)病患的治療
|
CN113164780A
(zh)
|
2018-10-10 |
2021-07-23 |
泰洛斯治疗公司 |
抗lap抗体变体及其用途
|
EP3876957A1
(en)
|
2018-11-05 |
2021-09-15 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients refractory for anti-pd-1 antibody
|
WO2020112781A1
(en)
|
2018-11-28 |
2020-06-04 |
Bristol-Myers Squibb Company |
Antibodies comprising modified heavy constant regions
|
WO2020116560A1
(ja)
|
2018-12-05 |
2020-06-11 |
株式会社バイカ・セラピュティクス |
抗体のFc領域改変体
|
WO2020118011A1
(en)
|
2018-12-06 |
2020-06-11 |
Alexion Pharmaceuticals, Inc. |
Anti-alk2 antibodies and uses thereof
|
US20220089786A1
(en)
|
2019-01-04 |
2022-03-24 |
Resolve Therapeutics, Llc |
Treatment of sjogren's disease with nuclease fusion proteins
|
BR112021014106A2
(pt)
|
2019-01-22 |
2021-10-13 |
Bristol-Myers Squibb Company |
Anticorpos contra subunidade alfa de il-7r e usos dos mesmos
|
EP3931310A1
(en)
|
2019-03-01 |
2022-01-05 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
CN113613676A
(zh)
|
2019-03-19 |
2021-11-05 |
中外制药株式会社 |
包含对抗原的结合活性因mta而变化的抗原结合结构域的抗原结合分子及用于获得该抗原结合结构域的文库
|
AU2020253455A1
(en)
|
2019-04-03 |
2021-11-04 |
Genzyme Corporation |
Anti-alpha beta TCR binding polypeptides with reduced fragmentation
|
CN111909268B
(zh)
*
|
2019-05-07 |
2022-04-19 |
北京天成新脉生物技术有限公司 |
低免疫原性低ADCC/CDC功能抗TNF-α人源化单克隆抗体TCX060及其应用
|
CN114174326A
(zh)
|
2019-06-18 |
2022-03-11 |
拜耳公司 |
长期稳定的肾上腺髓质素类似物及其用途
|
JP2022540904A
(ja)
|
2019-07-15 |
2022-09-20 |
ブリストル-マイヤーズ スクイブ カンパニー |
ヒトtrem-1に対する抗体およびその使用
|
US20220372139A1
(en)
|
2019-07-15 |
2022-11-24 |
Bristol-Myers Squibb Company |
Anti-trem-1 antibodies and uses thereof
|
GB201910900D0
(en)
|
2019-07-31 |
2019-09-11 |
Scancell Ltd |
Modified fc-regions to enhance functional affinity of antibodies and antigen binding fragments thereof
|
EP4031575A1
(en)
|
2019-09-19 |
2022-07-27 |
Bristol-Myers Squibb Company |
Antibodies binding to vista at acidic ph
|
JP2022549932A
(ja)
|
2019-09-30 |
2022-11-29 |
バイオベラティブ セラピューティクス インコーポレイテッド |
レンチウイルスベクター製剤
|
TW202140553A
(zh)
|
2020-01-13 |
2021-11-01 |
美商威特拉公司 |
C5ar1抗體分子及其用途
|
EP4100426A1
(en)
|
2020-02-06 |
2022-12-14 |
Bristol-Myers Squibb Company |
Il-10 and uses thereof
|
AU2021225962A1
(en)
|
2020-02-28 |
2022-10-20 |
Genzyme Corporation |
Modified binding polypeptides for optimized drug conjugation
|
US20230107644A1
(en)
|
2020-04-01 |
2023-04-06 |
University Of Rochester |
Monoclonal antibodies against the hemagglutinin (ha) and neuraminidase (na) of influenza h3n2 viruses
|
EP4132971A1
(en)
|
2020-04-09 |
2023-02-15 |
Merck Sharp & Dohme LLC |
Affinity matured anti-lap antibodies and uses thereof
|
EP3921034A2
(en)
|
2020-04-28 |
2021-12-15 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies and methods of use thereof
|
US20230192867A1
(en)
|
2020-05-15 |
2023-06-22 |
Bristol-Myers Squibb Company |
Antibodies to garp
|
US20230357341A1
(en)
|
2020-06-10 |
2023-11-09 |
Bica Therapeutics Inc. |
Fusion protein containing erythropoietin polypeptide
|
CA3165342A1
(en)
|
2020-06-29 |
2022-01-06 |
James Arthur Posada |
Treatment of sjogren's syndrome with nuclease fusion proteins
|
WO2022076606A1
(en)
|
2020-10-06 |
2022-04-14 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
EP4225330A1
(en)
|
2020-10-06 |
2023-08-16 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
JP2023548878A
(ja)
|
2020-11-04 |
2023-11-21 |
ザ ロックフェラー ユニバーシティー |
中和抗sars-cov-2抗体
|
US20240131064A1
(en)
|
2020-12-11 |
2024-04-25 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with braf inhibitors and/or mek inhibitors
|
JP2024500403A
(ja)
|
2020-12-17 |
2024-01-09 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
腫瘍浸潤リンパ球によるがんの治療
|
EP4262811A1
(en)
|
2020-12-17 |
2023-10-25 |
Iovance Biotherapeutics, Inc. |
Treatment with tumor infiltrating lymphocyte therapies in combination with ctla-4 and pd-1 inhibitors
|
JP2023554456A
(ja)
|
2020-12-18 |
2023-12-27 |
チューハイ トリノマブ ファーマシューティカル カンパニー リミテッド |
呼吸器合胞体ウイルスに特異的に結合する分子
|
EP4271791A2
(en)
|
2020-12-31 |
2023-11-08 |
Iovance Biotherapeutics, Inc. |
Devices and processes for automated production of tumor infiltrating lymphocytes
|
TW202246331A
(zh)
|
2021-01-13 |
2022-12-01 |
美商威特拉公司 |
人源化補體5a受體1抗體及其使用方法
|
EP4277926A1
(en)
|
2021-01-15 |
2023-11-22 |
The Rockefeller University |
Neutralizing anti-sars-cov-2 antibodies
|
JP2024506557A
(ja)
|
2021-01-29 |
2024-02-14 |
アイオバンス バイオセラピューティクス,インコーポレイテッド |
修飾された腫瘍浸潤リンパ球を作製する方法及び養子細胞療法におけるそれらの使用
|
CA3210755A1
(en)
|
2021-03-05 |
2022-09-09 |
Kenneth ONIMUS |
Tumor storage and cell culture compositions
|
WO2022198141A1
(en)
|
2021-03-19 |
2022-09-22 |
Iovance Biotherapeutics, Inc. |
Methods for tumor infiltrating lymphocyte (til) expansion related to cd39/cd69 selection and gene knockout in tils
|
CN118019546A
(zh)
|
2021-03-23 |
2024-05-10 |
艾欧凡斯生物治疗公司 |
肿瘤浸润淋巴细胞的cish基因编辑及其在免疫疗法中的用途
|
US20220313806A1
(en)
|
2021-03-25 |
2022-10-06 |
Iovance Biotherapeutics, Inc. |
Methods and compositions for t-cell coculture potency assays and use with cell therapy products
|
EP4314068A1
(en)
|
2021-04-02 |
2024-02-07 |
The Regents Of The University Of California |
Antibodies against cleaved cdcp1 and uses thereof
|
BR112023021665A2
(pt)
|
2021-04-19 |
2023-12-19 |
Iovance Biotherapeutics Inc |
Método para tratar um câncer, e, composição
|
WO2022235867A2
(en)
|
2021-05-06 |
2022-11-10 |
The Rockefeller University |
Neutralizing anti-sars- cov-2 antibodies and methods of use thereof
|
CA3219148A1
(en)
|
2021-05-17 |
2022-11-24 |
Frederick G. Vogt |
Pd-1 gene-edited tumor infiltrating lymphocytes and uses of same in immunotherapy
|
WO2023004074A2
(en)
|
2021-07-22 |
2023-01-26 |
Iovance Biotherapeutics, Inc. |
Method for cryopreservation of solid tumor fragments
|
TW202327631A
(zh)
|
2021-07-28 |
2023-07-16 |
美商艾歐凡斯生物治療公司 |
利用腫瘤浸潤性淋巴球療法與kras抑制劑組合治療癌症患者
|
IL311333A
(en)
|
2021-09-09 |
2024-05-01 |
Iovance Biotherapeutics Inc |
Processes for the production of TIL products using a strong PD-1 TALEN
|
CA3232700A1
(en)
|
2021-09-24 |
2023-03-30 |
Rafael CUBAS |
Expansion processes and agents for tumor infiltrating lymphocytes
|
AR127482A1
(es)
|
2021-10-27 |
2024-01-31 |
Iovance Biotherapeutics Inc |
Sistemas y métodos para coordinar la fabricación de células para inmunoterapia específica de paciente
|
WO2023086803A1
(en)
|
2021-11-10 |
2023-05-19 |
Iovance Biotherapeutics, Inc. |
Methods of expansion treatment utilizing cd8 tumor infiltrating lymphocytes
|
WO2023147399A1
(en)
|
2022-01-27 |
2023-08-03 |
The Rockefeller University |
Broadly neutralizing anti-sars-cov-2 antibodies targeting the n-terminal domain of the spike protein and methods of use thereof
|
WO2023147488A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
Cytokine associated tumor infiltrating lymphocytes compositions and methods
|
WO2023147486A1
(en)
|
2022-01-28 |
2023-08-03 |
Iovance Biotherapeutics, Inc. |
Tumor infiltrating lymphocytes engineered to express payloads
|
WO2023196877A1
(en)
|
2022-04-06 |
2023-10-12 |
Iovance Biotherapeutics, Inc. |
Treatment of nsclc patients with tumor infiltrating lymphocyte therapies
|
WO2023201369A1
(en)
|
2022-04-15 |
2023-10-19 |
Iovance Biotherapeutics, Inc. |
Til expansion processes using specific cytokine combinations and/or akti treatment
|
WO2023220608A1
(en)
|
2022-05-10 |
2023-11-16 |
Iovance Biotherapeutics, Inc. |
Treatment of cancer patients with tumor infiltrating lymphocyte therapies in combination with an il-15r agonist
|
WO2024011114A1
(en)
|
2022-07-06 |
2024-01-11 |
Iovance Biotherapeutics, Inc. |
Devices and processes for automated production of tumor infiltrating lymphocytes
|
US20240132622A1
(en)
|
2022-07-22 |
2024-04-25 |
Bristol-Myers Squibb Company |
Antibodies Binding to Human PAD4 and Uses Thereof
|
WO2024030758A1
(en)
|
2022-08-01 |
2024-02-08 |
Iovance Biotherapeutics, Inc. |
Chimeric costimulatory receptors, chemokine receptors, and the use of same in cellular immunotherapies
|
US20240101691A1
(en)
|
2022-09-21 |
2024-03-28 |
Sanofi Biotechnology |
Humanized anti-il-1r3 antibody and methods of use
|
WO2024089609A1
(en)
|
2022-10-25 |
2024-05-02 |
Ablynx N.V. |
Glycoengineered fc variant polypeptides with enhanced effector function
|
WO2024098024A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Expansion of tumor infiltrating lymphocytes from liquid tumors and therapeutic uses thereof
|
WO2024098027A1
(en)
|
2022-11-04 |
2024-05-10 |
Iovance Biotherapeutics, Inc. |
Methods for tumor infiltrating lymphocyte (til) expansion related to cd39/cd103 selection
|