DE69819519D1 - Bergamottin enthaltende zusammensetzungen zur erhöhung der oralen bioverfügbarkeit von pharmazeutika - Google Patents

Bergamottin enthaltende zusammensetzungen zur erhöhung der oralen bioverfügbarkeit von pharmazeutika

Info

Publication number
DE69819519D1
DE69819519D1 DE69819519T DE69819519T DE69819519D1 DE 69819519 D1 DE69819519 D1 DE 69819519D1 DE 69819519 T DE69819519 T DE 69819519T DE 69819519 T DE69819519 T DE 69819519T DE 69819519 D1 DE69819519 D1 DE 69819519D1
Authority
DE
Germany
Prior art keywords
bergamottin
pharmaceuticals
availability
increasing
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69819519T
Other languages
English (en)
Other versions
DE69819519T2 (de
Inventor
Kan He
Paul Hollenberg
F Woolf
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of DE69819519D1 publication Critical patent/DE69819519D1/de
Application granted granted Critical
Publication of DE69819519T2 publication Critical patent/DE69819519T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A61K31/37—Coumarins, e.g. psoralen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE69819519T 1997-08-19 1998-08-11 Bergamottin enthaltende zusammensetzungen zur erhöhung der oralen bioverfügbarkeit von pharmazeutika Expired - Fee Related DE69819519T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US5612997P 1997-08-19 1997-08-19
US56129P 1997-08-19
PCT/US1998/016579 WO1999008676A1 (en) 1997-08-19 1998-08-11 Compositions containing bergamottin for increasing the oral bioavailability of pharmaceutical agents

Publications (2)

Publication Number Publication Date
DE69819519D1 true DE69819519D1 (de) 2003-12-11
DE69819519T2 DE69819519T2 (de) 2004-09-23

Family

ID=22002350

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69819519T Expired - Fee Related DE69819519T2 (de) 1997-08-19 1998-08-11 Bergamottin enthaltende zusammensetzungen zur erhöhung der oralen bioverfügbarkeit von pharmazeutika

Country Status (15)

Country Link
US (1) US6509371B1 (de)
EP (1) EP1007034B1 (de)
JP (1) JP2001515035A (de)
KR (1) KR100510809B1 (de)
AT (1) ATE253357T1 (de)
AU (1) AU747051B2 (de)
BR (1) BR9812131A (de)
CA (1) CA2291233C (de)
DE (1) DE69819519T2 (de)
DK (1) DK1007034T3 (de)
ES (1) ES2209184T3 (de)
NZ (1) NZ502668A (de)
PT (1) PT1007034E (de)
WO (1) WO1999008676A1 (de)
ZA (1) ZA987436B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1014575A3 (fr) * 2002-01-16 2004-01-13 Chapelle Andre Composition a base de 5,7 dmc et/ou de bergamottine.
US7169763B2 (en) * 2002-02-22 2007-01-30 Oliver Yoa-Pu Hu Cytochrome P450 3A inhibitors and enhancers
WO2006077975A1 (ja) 2005-01-21 2006-07-27 Arkray, Inc. メタボリックシンドローム改善剤、ならびにそれを含む医薬、サプリメント、機能性食品および食品添加物
JP4902964B2 (ja) * 2005-03-30 2012-03-21 株式会社ファンケル 薬物の代謝阻害剤とその使用
KR102245421B1 (ko) 2013-05-30 2021-04-29 큐라디즘 약학적 조성물, 이의 제조방법 및 이의 용도
FI3229776T3 (fi) 2014-11-25 2023-08-15 Curadigm Sas Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt
AR102780A1 (es) * 2014-11-25 2017-03-22 Nanobiotix Composiciones farmacéuticas, su preparación y sus usos
KR101729494B1 (ko) 2015-06-29 2017-04-25 제주대학교 산학협력단 6,7-디하이드록시 베르가모틴을 함유한 화장료 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2996838B2 (ja) * 1993-07-12 2000-01-11 株式会社ポッカコーポレーション 抗菌剤
US5567592A (en) 1994-02-02 1996-10-22 Regents Of The University Of California Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal
US5916566A (en) * 1995-06-07 1999-06-29 Avmax, Inc. Use of benzoin gum to inhibit P-glycoprotein-mediated resistance of pharmaceutical compounds
US5665386A (en) 1995-06-07 1997-09-09 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
US5716928A (en) 1995-06-07 1998-02-10 Avmax, Inc. Use of essential oils to increase bioavailability of oral pharmaceutical compounds
US6160006A (en) * 1996-10-18 2000-12-12 Wayne State University 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor in grapefruit

Also Published As

Publication number Publication date
WO1999008676A1 (en) 1999-02-25
KR20010023034A (ko) 2001-03-26
AU8777098A (en) 1999-03-08
DK1007034T3 (da) 2004-03-22
CA2291233A1 (en) 1999-02-25
AU747051B2 (en) 2002-05-09
US6509371B1 (en) 2003-01-21
ATE253357T1 (de) 2003-11-15
EP1007034A1 (de) 2000-06-14
BR9812131A (pt) 2000-07-18
ES2209184T3 (es) 2004-06-16
JP2001515035A (ja) 2001-09-18
KR100510809B1 (ko) 2005-08-31
ZA987436B (en) 1999-02-22
DE69819519T2 (de) 2004-09-23
EP1007034B1 (de) 2003-11-05
NZ502668A (en) 2001-10-26
PT1007034E (pt) 2004-03-31
CA2291233C (en) 2006-10-10

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee