ZA987436B - Method of increasing oral bioavailability of compounds - Google Patents
Method of increasing oral bioavailability of compoundsInfo
- Publication number
- ZA987436B ZA987436B ZA987436A ZA987436A ZA987436B ZA 987436 B ZA987436 B ZA 987436B ZA 987436 A ZA987436 A ZA 987436A ZA 987436 A ZA987436 A ZA 987436A ZA 987436 B ZA987436 B ZA 987436B
- Authority
- ZA
- South Africa
- Prior art keywords
- oral bioavailability
- compounds
- compound
- increasing oral
- grapefruit juice
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 235000015201 grapefruit juice Nutrition 0.000 abstract 2
- DBMJZOMNXBSRED-UHFFFAOYSA-N Bergamottin Natural products O1C(=O)C=CC2=C1C=C1OC=CC1=C2OCC=C(C)CCC=C(C)C DBMJZOMNXBSRED-UHFFFAOYSA-N 0.000 abstract 1
- 102000002004 Cytochrome P-450 Enzyme System Human genes 0.000 abstract 1
- 108010015742 Cytochrome P-450 Enzyme System Proteins 0.000 abstract 1
- DBMJZOMNXBSRED-OQLLNIDSSA-N bergomottin Chemical compound O1C(=O)C=CC2=C1C=C1OC=CC1=C2OC/C=C(C)/CCC=C(C)C DBMJZOMNXBSRED-OQLLNIDSSA-N 0.000 abstract 1
- 230000005764 inhibitory process Effects 0.000 abstract 1
- 210000000936 intestine Anatomy 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
- A61K31/37—Coumarins, e.g. psoralen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5612997P | 1997-08-19 | 1997-08-19 |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA987436B true ZA987436B (en) | 1999-02-22 |
Family
ID=22002350
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA987436A ZA987436B (en) | 1997-08-19 | 1998-08-18 | Method of increasing oral bioavailability of compounds |
Country Status (15)
Country | Link |
---|---|
US (1) | US6509371B1 (xx) |
EP (1) | EP1007034B1 (xx) |
JP (1) | JP2001515035A (xx) |
KR (1) | KR100510809B1 (xx) |
AT (1) | ATE253357T1 (xx) |
AU (1) | AU747051B2 (xx) |
BR (1) | BR9812131A (xx) |
CA (1) | CA2291233C (xx) |
DE (1) | DE69819519T2 (xx) |
DK (1) | DK1007034T3 (xx) |
ES (1) | ES2209184T3 (xx) |
NZ (1) | NZ502668A (xx) |
PT (1) | PT1007034E (xx) |
WO (1) | WO1999008676A1 (xx) |
ZA (1) | ZA987436B (xx) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE1014575A3 (fr) * | 2002-01-16 | 2004-01-13 | Chapelle Andre | Composition a base de 5,7 dmc et/ou de bergamottine. |
US7169763B2 (en) * | 2002-02-22 | 2007-01-30 | Oliver Yoa-Pu Hu | Cytochrome P450 3A inhibitors and enhancers |
WO2006077975A1 (ja) | 2005-01-21 | 2006-07-27 | Arkray, Inc. | メタボリックシンドローム改善剤、ならびにそれを含む医薬、サプリメント、機能性食品および食品添加物 |
JP4902964B2 (ja) * | 2005-03-30 | 2012-03-21 | 株式会社ファンケル | 薬物の代謝阻害剤とその使用 |
KR102245421B1 (ko) | 2013-05-30 | 2021-04-29 | 큐라디즘 | 약학적 조성물, 이의 제조방법 및 이의 용도 |
FI3229776T3 (fi) | 2014-11-25 | 2023-08-15 | Curadigm Sas | Farmaseuttinen koostumus, joka yhdistää ainakin kaksi erillistä nanopartikkelia ja farmaseuttisen yhdisteen, sen valmistus ja käytöt |
AR102780A1 (es) * | 2014-11-25 | 2017-03-22 | Nanobiotix | Composiciones farmacéuticas, su preparación y sus usos |
KR101729494B1 (ko) | 2015-06-29 | 2017-04-25 | 제주대학교 산학협력단 | 6,7-디하이드록시 베르가모틴을 함유한 화장료 조성물 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2996838B2 (ja) * | 1993-07-12 | 2000-01-11 | 株式会社ポッカコーポレーション | 抗菌剤 |
US5567592A (en) | 1994-02-02 | 1996-10-22 | Regents Of The University Of California | Screening method for the identification of bioenhancers through the inhibition of P-glycoprotein transport in the gut of a mammal |
US5916566A (en) * | 1995-06-07 | 1999-06-29 | Avmax, Inc. | Use of benzoin gum to inhibit P-glycoprotein-mediated resistance of pharmaceutical compounds |
US5665386A (en) | 1995-06-07 | 1997-09-09 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
US5716928A (en) | 1995-06-07 | 1998-02-10 | Avmax, Inc. | Use of essential oils to increase bioavailability of oral pharmaceutical compounds |
US6160006A (en) * | 1996-10-18 | 2000-12-12 | Wayne State University | 6',7'-dihydroxybergamottin, a cytochrome P450 inhibitor in grapefruit |
-
1998
- 1998-08-11 AT AT98939311T patent/ATE253357T1/de not_active IP Right Cessation
- 1998-08-11 US US09/486,117 patent/US6509371B1/en not_active Expired - Fee Related
- 1998-08-11 CA CA002291233A patent/CA2291233C/en not_active Expired - Fee Related
- 1998-08-11 WO PCT/US1998/016579 patent/WO1999008676A1/en active IP Right Grant
- 1998-08-11 DK DK98939311T patent/DK1007034T3/da active
- 1998-08-11 AU AU87770/98A patent/AU747051B2/en not_active Ceased
- 1998-08-11 KR KR10-2000-7001649A patent/KR100510809B1/ko not_active IP Right Cessation
- 1998-08-11 EP EP98939311A patent/EP1007034B1/en not_active Expired - Lifetime
- 1998-08-11 DE DE69819519T patent/DE69819519T2/de not_active Expired - Fee Related
- 1998-08-11 PT PT98939311T patent/PT1007034E/pt unknown
- 1998-08-11 BR BR9812131-6A patent/BR9812131A/pt not_active Application Discontinuation
- 1998-08-11 JP JP2000509416A patent/JP2001515035A/ja not_active Abandoned
- 1998-08-11 NZ NZ502668A patent/NZ502668A/en unknown
- 1998-08-11 ES ES98939311T patent/ES2209184T3/es not_active Expired - Lifetime
- 1998-08-18 ZA ZA987436A patent/ZA987436B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
WO1999008676A1 (en) | 1999-02-25 |
KR20010023034A (ko) | 2001-03-26 |
AU8777098A (en) | 1999-03-08 |
DK1007034T3 (da) | 2004-03-22 |
CA2291233A1 (en) | 1999-02-25 |
AU747051B2 (en) | 2002-05-09 |
US6509371B1 (en) | 2003-01-21 |
DE69819519D1 (de) | 2003-12-11 |
ATE253357T1 (de) | 2003-11-15 |
EP1007034A1 (en) | 2000-06-14 |
BR9812131A (pt) | 2000-07-18 |
ES2209184T3 (es) | 2004-06-16 |
JP2001515035A (ja) | 2001-09-18 |
KR100510809B1 (ko) | 2005-08-31 |
DE69819519T2 (de) | 2004-09-23 |
EP1007034B1 (en) | 2003-11-05 |
NZ502668A (en) | 2001-10-26 |
PT1007034E (pt) | 2004-03-31 |
CA2291233C (en) | 2006-10-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IL161154A0 (en) | Inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1 | |
WO2001052921A3 (en) | Valve arrangement | |
NZ514574A (en) | Novel method of treatment | |
WO2001024816A3 (en) | Compositions and methods relating to the inhibition of casomorphin and gluteomorphin | |
CA2330128A1 (en) | Food compositions, compositions for oral cavity and medicinal compositions for preventing or treating periodontosis and method for preventing or treating periodontosis | |
WO2001032183A3 (en) | Pharmaceutical compositions comprising oxcarbazepine | |
ATE240103T1 (de) | Intermediaires des produits definitifs de glycosylation avancee et inhibition des produits age post-amadori | |
AU2003202159A1 (en) | Extract of processed panax genus plant, the preparation method thereof, and compositions containing the same | |
CA2312936A1 (en) | Compositions and methods for weight reduction | |
RS44204A (xx) | Inhibitori 11-beta- hidroksistereoidne dehidrogenaze tipa 1 | |
ZA987436B (en) | Method of increasing oral bioavailability of compounds | |
FR2827774B1 (fr) | Preparations pharmaceutiques et/ou dietetiques contenant un extrait vegetal titre en composes actifs et des micro-organismes probiotiques | |
IL149360A0 (en) | Method and compositions for administering taxanes orally to human patients | |
HUP0003546A3 (en) | Compositions for administering taxanes orally to human patients | |
AU5634500A (en) | Dietary calcium as a supplement to vitamin d compound treatment of multiple sclerosis | |
RS44304A (xx) | Inhibitori 11-beta- hidroksistereoidne dehidrogenaze tipa 1 | |
DK1242067T3 (da) | Calciumformiat som et kosttilskud | |
WO2001024803A3 (en) | Pharmaceutical compositions containing copper, salicylic acid and vitamines c | |
MY121604A (en) | Combination therapy for hiv infection using the hiv protease inhibitor indinavir and the reverse transcriptase inhibitor 3tc together with azt | |
HUP0101326A2 (hu) | Paroxetinkompozíciók és eljárás az előállításukra | |
NZ512525A (en) | Skin whitening compositions for oral administration comprising a solvent extract from the plant of the genus Rosaceae Pyracantha | |
HK1075390A1 (en) | Citalopram for the treatment of elevated blood pressure | |
AU4034800A (en) | Novel compositions and methods for prevention and treatment of protozoal disease | |
AU6725300A (en) | Non-hygroscopic salts of active ingredients having therapeutical and/or nutritional activities and orally administrable compositions containing same | |
WO1998056759A3 (de) | Neue pentaerythritderivate, deren herstellung und verwendung sowie intermediate zur synthese derselben |