DE69712332T2 - Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung - Google Patents

Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung

Info

Publication number
DE69712332T2
DE69712332T2 DE69712332T DE69712332T DE69712332T2 DE 69712332 T2 DE69712332 T2 DE 69712332T2 DE 69712332 T DE69712332 T DE 69712332T DE 69712332 T DE69712332 T DE 69712332T DE 69712332 T2 DE69712332 T2 DE 69712332T2
Authority
DE
Germany
Prior art keywords
production
tablets containing
lactam antibiotic
containing beta
beta lactam
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69712332T
Other languages
English (en)
Other versions
DE69712332D1 (de
Inventor
Hisami Yamaguchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Astellas Pharma Inc
Original Assignee
Fujisawa Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co Ltd filed Critical Fujisawa Pharmaceutical Co Ltd
Publication of DE69712332D1 publication Critical patent/DE69712332D1/de
Application granted granted Critical
Publication of DE69712332T2 publication Critical patent/DE69712332T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Seasonings (AREA)
DE69712332T 1996-02-29 1997-02-21 Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung Expired - Lifetime DE69712332T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP4274396 1996-02-29
JP32026496 1996-11-29
PCT/JP1997/000509 WO1997031639A1 (fr) 1996-02-29 1997-02-21 COMPRIMES CONTENANT UN ANTIBIOTIQUE AU β-LACTAME ET PROCEDE POUR LEUR PRODUCTION

Publications (2)

Publication Number Publication Date
DE69712332D1 DE69712332D1 (de) 2002-06-06
DE69712332T2 true DE69712332T2 (de) 2002-10-02

Family

ID=26382481

Family Applications (2)

Application Number Title Priority Date Filing Date
DE69712332T Expired - Lifetime DE69712332T2 (de) 1996-02-29 1997-02-21 Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung
DE69732312T Active DE69732312T8 (de) 1996-02-29 1997-02-21 Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69732312T Active DE69732312T8 (de) 1996-02-29 1997-02-21 Schnellzerfallendes Granulate von einem synthetischen Süssstoff enthaltend Kieselsäure und/oder Siliciumdioxid

Country Status (24)

Country Link
US (4) US6423341B1 (de)
EP (2) EP1166651B1 (de)
JP (1) JP3180350B2 (de)
KR (1) KR20040058360A (de)
CN (2) CN1136853C (de)
AR (1) AR006012A1 (de)
AT (2) ATE287218T1 (de)
AU (1) AU724946B2 (de)
BR (1) BR9707780A (de)
CA (1) CA2248179C (de)
DE (2) DE69712332T2 (de)
DK (2) DK1166651T3 (de)
EA (1) EA001089B1 (de)
ES (2) ES2173420T3 (de)
HK (1) HK1015684A1 (de)
HU (1) HU227821B1 (de)
IL (1) IL125214A0 (de)
MX (1) MX9806265A (de)
NZ (2) NZ330864A (de)
PT (2) PT1166651E (de)
TR (1) TR199801680T2 (de)
TW (1) TW473393B (de)
WO (1) WO1997031639A1 (de)
ZA (1) ZA971584B (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746105B2 (en) 1997-07-15 2004-06-08 Silverbrook Research Pty. Ltd. Thermally actuated ink jet printing mechanism having a series of thermal actuator units
US5948440A (en) * 1997-12-17 1999-09-07 Ranbaxy Laboratories Limited Modified release matrix formulation of cefaclor and cephalexin
DK1736144T3 (en) 1998-05-18 2015-12-07 Takeda Pharmaceutical Orally disintegrating tablets.
EP1561458B1 (de) * 1998-07-28 2010-09-15 Takeda Pharmaceutical Company Limited Leicht zerfallende feste Zubereitung
US20080113025A1 (en) * 1998-11-02 2008-05-15 Elan Pharma International Limited Compositions comprising nanoparticulate naproxen and controlled release hydrocodone
US20070160675A1 (en) * 1998-11-02 2007-07-12 Elan Corporation, Plc Nanoparticulate and controlled release compositions comprising a cephalosporin
WO2001027103A1 (en) 1999-10-08 2001-04-19 Smithkline Beecham Corporation Fab i inhibitors
CA2311734C (en) * 2000-04-12 2011-03-08 Bristol-Myers Squibb Company Flash-melt oral dosage formulation
FR2814679B1 (fr) * 2000-09-29 2003-04-11 Cll Pharma Compositions pharmaceutiques dispersibles a base de cephalosporines, leur procede de preparation et leur utilisation
JP4387804B2 (ja) * 2001-04-06 2009-12-24 アフィニアム・ファーマシューティカルズ・インコーポレイテッド ＦａｂＩ阻害剤
GB0123400D0 (en) * 2001-09-28 2001-11-21 Novartis Ag Organic compounds
GB0209265D0 (en) 2002-04-23 2002-06-05 Novartis Ag Organic compounds
TW200404550A (en) * 2002-07-08 2004-04-01 Sankyo Co Cepharospolin formulation for oral use
JP4526247B2 (ja) * 2002-07-08 2010-08-18 第一三共株式会社 経口用セファロスポリン製剤
EP1842852A1 (de) * 2002-08-13 2007-10-10 Sandoz AG Ein cefdinir-zwischenprodukt
SI1575951T1 (sl) 2002-12-06 2014-10-30 Debiopharm International Sa Forum "Apres-Demain" Heterociklične spojine, postopki za njihovo izdelavo in njihova uporaba v terapiji
DE602004016831D1 (de) * 2003-03-17 2008-11-13 Affinium Pharm Inc Pharmazeutische zusammensetzungen inhibitoren von fab i und weitere antibiotika enthaltend
AU2004224045A1 (en) * 2003-03-24 2004-10-07 Sandoz Ag Novel crystal of 7-[2-(2-aminothiazole-4-yl)-2-hydroxyiminoacetamido-3-vinyl-3-cephem-4-carboxylic acid (syn isomer) and method for preparation thereof
KR100882156B1 (ko) * 2003-08-08 2009-02-06 아지노모토 가부시키가이샤 나테글리니드 함유 제제
US20050113355A1 (en) * 2003-09-12 2005-05-26 Duerst Richard W. Cefdinir pyridine salt
US20050059818A1 (en) * 2003-09-12 2005-03-17 Duerst Richard W. Polymorph of a pharmaceutical
US20050059819A1 (en) * 2003-09-12 2005-03-17 Duerst Richard W. Cefdinir pyridine salt
JP2005162696A (ja) * 2003-12-04 2005-06-23 Nichiko Pharmaceutical Co Ltd 溶出性に優れたセフジトレンピボキシル製剤
US20050131079A1 (en) * 2003-12-10 2005-06-16 Pujara Chetan P. Cefdinir oral suspension
US20080139528A1 (en) * 2003-12-10 2008-06-12 Pujara Chetan P Cefdinir oral suspension
US20060211676A1 (en) * 2004-03-16 2006-09-21 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060142563A1 (en) * 2004-03-16 2006-06-29 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060142261A1 (en) * 2004-03-16 2006-06-29 Devalina Law Crystalline anhydrous cefdinir and crystalline cefdinir hydrates
US20060069079A1 (en) * 2004-09-27 2006-03-30 Sever Nancy E Stable amorphous cefdinir
JP2007536378A (ja) * 2004-05-10 2007-12-13 ルピン・リミテッド 生体利用性が強化されている新規セフィキシム医薬製剤
JP2006527064A (ja) * 2004-05-31 2006-11-30 サンア ファーマシューティカルス カンパニー リミテッド β−ラクタム系抗生物質を含む懸濁錠剤及びその製造方法
JP5087406B2 (ja) * 2004-06-04 2012-12-05 アフィニウム ファーマシューティカルズ， インク． 治療薬ならびにその製造方法および使用方法
US20060099253A1 (en) * 2004-10-20 2006-05-11 Wyeth Antibiotic product formulation
IL169678A (en) 2005-07-14 2010-11-30 Innova Sa Sweetener compositions
US20090156578A1 (en) * 2005-12-05 2009-06-18 PAULS Henry 3-Heterocyclylacrylamide Compounds as Fab I Inhibitors and Antibacterial Agents
US20070128268A1 (en) * 2005-12-07 2007-06-07 Herwig Jennewein Pharmaceutical compositions comprising an antibiotic
US20090197855A1 (en) * 2006-05-01 2009-08-06 Makarand Krishnakumar Avachat Pharmaceutical compositions of cefdinir
JP5468899B2 (ja) * 2006-07-20 2014-04-09 アフィニウム ファーマシューティカルズ， インク． Ｆａｂｉインヒビターとしてのアクリルアミド誘導体
JP5274261B2 (ja) * 2006-12-07 2013-08-28 第一三共株式会社 低置換度ヒドロキシプロピルセルロースを含有する医薬組成物
WO2008072533A1 (ja) * 2006-12-07 2008-06-19 Daiichi Sankyo Company, Limited 固形製剤の製造方法
KR101442862B1 (ko) * 2006-12-07 2014-09-22 다이이찌 산쿄 가부시키가이샤 만니톨 또는 유당을 함유하는 고형 제제
US8263613B2 (en) * 2007-02-16 2012-09-11 Affinium Pharmaceuticals, Inc. Salts, prodrugs and polymorphs of fab I inhibitors
WO2011078830A1 (en) * 2009-12-25 2011-06-30 Bilgic Mahmut Rapidly dispersing effervescent formulation
TR200909785A1 (tr) * 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Aktif ajan olarak sefdinir içeren farmasötik kompozisyonlar.
US8614315B2 (en) 2009-12-25 2013-12-24 Mahmut Bilgic Cefdinir and cefixime formulations and uses thereof
TR200909786A1 (tr) * 2009-12-25 2011-07-21 Bi̇lgi̇ç Mahmut Sefiksim içeren efervesan tablet ve granül formülasyonu.
TR201000686A1 (tr) * 2010-01-29 2011-08-22 B�Lg�� Mahmut Bakteriyel enfeksiyonların tedavisinde suda çözünebilir sefdinir ve klavulanik asit formülasyonları.@
TR201000687A1 (tr) * 2010-01-29 2011-08-22 Bi̇lgi̇ç Mahmut Aktif madde olarak sefiksim ve klavulanik asit içeren efervesan formülasyonlar
TR201001417A1 (tr) * 2010-02-25 2011-09-21 Sanovel İlaç San. Ve Ti̇c. A. Ş. Geliştirilmiş çözünme hızına sahip sefdinir formülasyonu
WO2011139249A2 (en) * 2010-05-04 2011-11-10 Mahmut Bilgic Pharmaceutical composition comprising cefdinir
EP2568959A2 (de) * 2010-05-14 2013-03-20 Mahmut Bilgic Formulierungen mit einem cephalosporin der dritten generation und clavulansäure
EA021874B1 (ru) * 2010-09-13 2015-09-30 ЛИМОНОВ, Виктор Львович Фармацевтическая композиция антимикробного действия для парентерального введения и способ ее получения
TR201009166A2 (tr) * 2010-11-05 2012-05-21 Bi̇lgi̇ç Mahmut Sefdinir içeren farmasötik bileşim için üretim yöntemi
TR201010212A2 (tr) * 2010-12-08 2012-06-21 Bi̇lgi̇ç Mahmut Sefdinir içeren katı oral dozaj formu.
CN104684922B (zh) 2012-06-19 2016-10-26 德彪药业国际股份公司 (e)-n-甲基-n-((3-甲基苯并呋喃-2-基)甲基)-3-(7-氧代-5,6,7,8-四氢-1,8-萘啶-3-基)丙烯酰胺的前药衍生物
WO2014051532A1 (en) * 2012-09-28 2014-04-03 Bilgic Mahmut Pharmaceutical tablet formulations comprising cefdinir
WO2014053468A1 (en) * 2012-10-02 2014-04-10 Montero Gida Sanayi Ve Ticaret A.S. Mogroside formulation and a production process thereof
WO2014057059A1 (en) 2012-10-11 2014-04-17 Sanovel Ilac Sanayi Ve Ticaret A.S. Effervescent cefdinir formulation
EP2815743A1 (de) 2013-06-21 2014-12-24 Sanovel Ilac Sanayi ve Ticaret A.S. Formulierungen mit Ceftibuten
US10207004B2 (en) 2014-04-04 2019-02-19 Douxmatok Ltd Method for producing sweetener compositions and sweetener compositions
US20160242439A1 (en) 2014-04-04 2016-08-25 Douxmatok Ltd Method for producing sweetener compositions and sweetener compositions
US10231476B2 (en) 2014-04-04 2019-03-19 Douxmatok Ltd Sweetener compositions and foods, beverages, and consumable products made thereof
JP6998881B2 (ja) 2016-02-26 2022-02-10 デビオファーム・インターナショナル・エス・アー 糖尿病性足感染症の処置のための医薬
CN115607514B (zh) * 2021-07-16 2023-12-12 广州白云山天心制药股份有限公司 一种含有头孢地尼颗粒的制备方法

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3098749A (en) * 1960-11-16 1963-07-23 Abbott Lab Sweetening agent and process of producing the same
US3336199A (en) * 1963-07-03 1967-08-15 Warner Lambert Pharmaceutical Tablet composition
DE2251250C3 (de) * 1972-10-19 1981-06-25 Hoechst Ag, 6230 Frankfurt Verfahren zur Herstellung hochdosierter Antibiotica-Tabletten
US4039673A (en) * 1973-10-30 1977-08-02 Bayer Aktiengesellschaft Penicillins and cephalosporins and their production
JPS5438167B2 (de) * 1974-04-27 1979-11-19
US4248894A (en) * 1979-01-17 1981-02-03 Life Savers, Inc. Long-lasting flavored chewing gum containing non-sugar sweetener codried on chalk or other filler and method
US4384005A (en) * 1980-09-26 1983-05-17 General Foods Corporation Non-friable, readily-soluble, compressed tablets and process for preparing same
JPS57150361A (en) * 1981-03-10 1982-09-17 Ajinomoto Co Inc Granule of dipeptide sweetener
US4352821A (en) * 1981-07-21 1982-10-05 Shaklee Corporation Sweet tableting agent
EP0080862B1 (de) * 1981-12-02 1985-09-25 Beecham Group Plc Pharmazeutische Zubereitung die Beta-Lactam Antibiotika enthält
JPS58198268A (ja) * 1982-05-14 1983-11-18 Ajinomoto Co Inc 甘味料顆粒又はキユ−ブの製造法
US4600579A (en) * 1983-06-07 1986-07-15 Mallinckrodt, Inc. N-acetyl-p-aminophenol compositions containing partially gelatinized starch and method for preparing same
US4752485A (en) * 1984-10-05 1988-06-21 Warner-Lambert Company Novel sweetener delivery systems
US4722845A (en) * 1986-12-23 1988-02-02 Warner-Lambert Company Stable cinnamon-flavored chewing gum composition
EP0281200B1 (de) * 1987-03-02 1994-01-19 Yamanouchi Europe B.V. Pharmazeutische Zusammensetzung, pharmazeutisches Granulat und Verfahren zu ihrer Herstellung
US4915948A (en) * 1987-08-31 1990-04-10 Warner-Lambert Company Tablets having improved bioadhesion to mucous membranes
JPH01206969A (ja) * 1987-10-30 1989-08-21 Takeda Chem Ind Ltd 甘味料顆粒の製造法
JPH01149728A (ja) * 1987-12-04 1989-06-12 Fujisawa Pharmaceut Co Ltd 抗潰瘍剤
FR2634355B1 (fr) * 1988-07-25 1990-09-14 Beghin Say Sa Nouveau produit edulcorant alimentaire a base de saccharose et d'edulcorant intense et son procede de preparation
US5085876A (en) * 1988-11-16 1992-02-04 The Nutrasweet Company Fast dissolving sweetening agent including caramel
US5114929A (en) * 1989-03-21 1992-05-19 Beecham Group P.L.C. Pharmaceutical formulation
FR2669221B1 (fr) * 1990-11-15 1993-01-15 Rhone Poulenc Sante Procede de preparation par compression directe de comprimes de derives de l'acide cephalosporanique.
GB9109862D0 (en) * 1991-05-08 1991-07-03 Beecham Lab Sa Pharmaceutical formulations
DE69331839T2 (de) * 1992-01-29 2002-12-12 Takeda Chemical Industries Ltd Schnellösliche Tablette und ihre Herstellung
ES2059260B1 (es) * 1992-10-06 1995-04-16 Espanola Prod Quimicos Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua.
JP3063438B2 (ja) * 1992-12-24 2000-07-12 田辺製薬株式会社 ドパミン誘導体含有経口投与用製剤
CA2168265C (en) * 1993-07-28 1999-02-23 Kiyoshi Kimura Antidepressant
JP2994956B2 (ja) * 1994-05-31 1999-12-27 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース、その組成物およびその錠剤
DE4418957A1 (de) * 1994-05-31 1995-12-07 Merck Patent Gmbh Cefixim-Zubereitung
ES2082723B1 (es) * 1994-07-20 1996-10-01 Lilly Sa Formulacion farmaceutica de fluoxetina en forma dispersable.
FR2722984B1 (fr) * 1994-07-26 1996-10-18 Effik Lab Procede de preparation de formes pharmaceutiques seches et les compositions pharmaceutiques ainsi realisees
ES2079327B1 (es) * 1994-12-13 1996-08-01 Lilly Sa Formulaciones farmaceuticas de cefaclor.

Also Published As

Publication number Publication date
ES2231369T3 (es) 2005-05-16
ZA971584B (en) 1997-09-10
ES2173420T3 (es) 2002-10-16
EA001089B1 (ru) 2000-10-30
WO1997031639A1 (fr) 1997-09-04
EP0890359B1 (de) 2002-05-02
CA2248179A1 (en) 1997-09-04
EP0890359A1 (de) 1999-01-13
CN1136853C (zh) 2004-02-04
HUP9901877A1 (hu) 1999-12-28
CN1212626A (zh) 1999-03-31
AU1734797A (en) 1997-09-16
US20070134325A1 (en) 2007-06-14
HU227821B1 (en) 2012-03-28
MX9806265A (es) 1998-12-31
EP1166651A1 (de) 2002-01-02
CN1409995A (zh) 2003-04-16
DE69712332D1 (de) 2002-06-06
DK1166651T3 (da) 2005-05-30
DK0890359T3 (da) 2002-07-01
EP0890359A4 (de) 1999-01-13
US6423341B1 (en) 2002-07-23
ATE216887T1 (de) 2002-05-15
JP3180350B2 (ja) 2001-06-25
PT890359E (pt) 2003-03-31
IL125214A0 (en) 1999-03-12
US20030129227A1 (en) 2003-07-10
HK1015684A1 (en) 1999-10-22
US20020192281A1 (en) 2002-12-19
ATE287218T1 (de) 2005-02-15
HUP9901877A3 (en) 2000-04-28
CA2248179C (en) 2007-09-18
DE69732312T8 (de) 2006-07-27
NZ330864A (en) 2001-07-27
EA199800775A1 (ru) 1999-02-25
EP1166651B1 (de) 2005-01-19
AU724946B2 (en) 2000-10-05
BR9707780A (pt) 1999-07-27
PT1166651E (pt) 2005-04-29
DE69732312D1 (de) 2005-02-24
TR199801680T2 (xx) 1999-02-22
AR006012A1 (es) 1999-07-21
KR20040058360A (ko) 2004-07-03
DE69732312T2 (de) 2006-04-06
US20020051816A1 (en) 2002-05-02
TW473393B (en) 2002-01-21
NZ512609A (en) 2003-03-28

Similar Documents

Publication Publication Date Title
DE69712332D1 (de) Beta-lactam-antibiotikum enthaltende tabletten und verfahren zu deren herstellung
DE69720523D1 (de) Polyolefin-polyethylenoxid-mischungen und verfahren zu deren herstellung
DE69635345D1 (de) Kautschukzusammensetzung und verfahren zu deren herstellung
DE59603890D1 (de) Bürste und verfahren zu deren herstellung
DE69611524D1 (de) Alkalische cellulase und verfahren zu deren herstellung
DE69604218D1 (de) Druckmaterial, Verfahren zu deren Herstellung und Aufzeichnungsverfahren
ATE279506T1 (de) Tabletten und verfahren zu deren herstellung
DE69523596T2 (de) Verbesserte verbundwerkstoffe und verfahren zu deren herstellung
DE69710484T2 (de) Übergezogene süsswaren und verfahren zu deren herstellung
DE69306615D1 (de) Verbundwalze und Verfahren zu ihrer Herstellung
DE69815126D1 (de) Pyrimidinderivate und verfahren zu deren herstellung
DE69810948D1 (de) Fulleren enthaltende struktur und verfahren zu deren herstellung
DE59608456D1 (de) Photodiode und verfahren zu deren herstellung
DE69713845D1 (de) Druckvorrichtung und verfahren zu deren herstellung
DE69721989D1 (de) Trennfolie und verfahren zu deren herstellung
DE69608359D1 (de) Hexaazaisowurtzitan-derivate und verfahren zu deren herstellung
DE69807501D1 (de) Leichtgewicht-flaschen und verfahren zu deren herstellung
DE69410763T2 (de) Microsphäre und Verfahren zu deren Herstellung
DE69620593T2 (de) Hexacyclische camptothecinanaloga und verfahren zu deren herstellung
DE69610481D1 (de) Prostaglandine und verfahren zu deren herstellung
DE69523571T2 (de) Pyridylimidazol-derivate und verfahren zu ihrer herstellung
DE69735099D1 (de) Antibiotika rk-1061 und verfahren zu ihrer herstellung
DE69615197D1 (de) Befestigungsvorrichtung und verfahren zu deren herstellung
DE69527445T2 (de) Aminooligosaccharid-derivate und verfahren zu ihrer herstellung
DE69602044D1 (de) Aufzeichnungsmaterial und Verfahren zu deren Herstellung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: ASTELLAS PHARMA INC., TOKIO/TOKYO, JP