CO5640150A2 - Tratamiento con anticuerpos anti-vegf - Google Patents

Tratamiento con anticuerpos anti-vegf

Info

Publication number
CO5640150A2
CO5640150A2 CO05121509A CO05121509A CO5640150A2 CO 5640150 A2 CO5640150 A2 CO 5640150A2 CO 05121509 A CO05121509 A CO 05121509A CO 05121509 A CO05121509 A CO 05121509A CO 5640150 A2 CO5640150 A2 CO 5640150A2
Authority
CO
Colombia
Prior art keywords
cancer
patient
neoplastic composition
treatment
vegf antibodies
Prior art date
Application number
CO05121509A
Other languages
English (en)
Inventor
Gwendolyn Fyfe
Eric Holmgren
Robert D Mass
William Novotny
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=33551495&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO5640150(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of CO5640150A2 publication Critical patent/CO5640150A2/es

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
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    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
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    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
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    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7068—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines having oxo groups directly attached to the pyrimidine ring, e.g. cytidine, cytidylic acid
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    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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Abstract

1.- Un método para tratar cáncer en un paciente humano, caracterizado porque comprende administrar al paciente cantidades efectivas de un anticuerpo anti-VEGF y una composición anti-neoplásica, en donde la composición anti-neoplásica comprende cuando menos un agente quimioterapéutico.2.- El método de conformidad con la reivindicación 1, caracterizado porque el cáncer se elige del grupo que consiste de cáncer de pecho, cáncer colorectal, cáncer rectal, cáncer pulmonar de células no pequeñas, linfoma no-Hodgkins (NHL), cáncer de células renales, cáncer de próstata, cáncer de hígado, cáncer pancreático, sarcoma de tejido suave, sarcoma de kaposi, carcinoma carcinoide, cáncer de cabeza y cuello, melanoma, cáncer de ovarios, mesotelioma y mieloma múltiple.3.- El método de conformidad con la reivindicación 1, caracterizado porque el cáncer es metastásico.4.- El método de conformidad con la reivindicación 1, caracterizado porque el paciente está sin tratamiento previo.
CO05121509A 2003-05-30 2005-11-30 Tratamiento con anticuerpos anti-vegf CO5640150A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US47448003P 2003-05-30 2003-05-30

Publications (1)

Publication Number Publication Date
CO5640150A2 true CO5640150A2 (es) 2006-05-31

Family

ID=33551495

Family Applications (1)

Application Number Title Priority Date Filing Date
CO05121509A CO5640150A2 (es) 2003-05-30 2005-11-30 Tratamiento con anticuerpos anti-vegf

Country Status (23)

Country Link
US (41) US20050186208A1 (es)
EP (4) EP2251355A1 (es)
JP (8) JP2007525466A (es)
KR (11) KR20060006975A (es)
CN (2) CN101274098A (es)
AU (2) AU2004251168A1 (es)
BR (1) BRPI0411200A (es)
CA (1) CA2526085A1 (es)
CO (1) CO5640150A2 (es)
CR (1) CR8108A (es)
EC (1) ECSP056187A (es)
IL (4) IL171833A (es)
MA (1) MA27854A1 (es)
ME (1) ME00425B (es)
MX (1) MXPA05012723A (es)
NO (1) NO20056236L (es)
NZ (1) NZ621449A (es)
RS (5) RS20050885A (es)
RU (4) RU2005136988A (es)
TN (1) TNSN05300A1 (es)
UA (1) UA101945C2 (es)
WO (1) WO2005000900A1 (es)
ZA (1) ZA200509059B (es)

Families Citing this family (249)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6582959B2 (en) * 1991-03-29 2003-06-24 Genentech, Inc. Antibodies to vascular endothelial cell growth factor
US7183387B1 (en) 1999-01-15 2007-02-27 Genentech, Inc. Polypeptide variants with altered effector function
DK1399484T3 (da) * 2001-06-28 2010-11-08 Domantis Ltd Dobbelt-specifik ligand og anvendelse af denne
US20050271663A1 (en) * 2001-06-28 2005-12-08 Domantis Limited Compositions and methods for treating inflammatory disorders
US9321832B2 (en) * 2002-06-28 2016-04-26 Domantis Limited Ligand
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