BR9912303A - Processo para a preparação de 2-isocianatopirimidinas 4,5-dissubstituìdas e seu emprego como produtos intermediários para sìnteses de substâncias ativas - Google Patents
Processo para a preparação de 2-isocianatopirimidinas 4,5-dissubstituìdas e seu emprego como produtos intermediários para sìnteses de substâncias ativasInfo
- Publication number
- BR9912303A BR9912303A BR9912303-7A BR9912303A BR9912303A BR 9912303 A BR9912303 A BR 9912303A BR 9912303 A BR9912303 A BR 9912303A BR 9912303 A BR9912303 A BR 9912303A
- Authority
- BR
- Brazil
- Prior art keywords
- formula
- preparation
- active substances
- synthesis
- intermediate products
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/32—One oxygen, sulfur or nitrogen atom
- C07D239/42—One nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/30—Halogen atoms or nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
Patente de Invenção: <B>''PROCESSO PARA A PREPARAçãO DE 2-ISOCIANATOPIRIMIDINAS 4,6-DISSUBSTITUìDAS E SEU EMPREGO COMO PRODUTOS INTERMEDIáRIOS PARA SìNTESES DE SUBSTâNCIAS ATIVAS''<D>. Isocianatos da fórmula (I), na qual X e Y são definidos tal como na fórmula (I) de acordo com a reivindicação (1), podem ser preparados, reagindo-se um composto da fórmula (II) ou seus sais, em que X e Y são definidos tal como na fórmula (I), com 1 até 6 moles de fosgênio para 1 mol de composto da fórmula (II), na presença de 2 até 3,5 equivalentes em mol de uma base por mol de composto da fórmula (II) e na presença de um solvente orgânico aprótico em uma temperatura de reação de -30 até +60°C para a formação do composto da fórmula (I). Os compostos (I) podem ser transformados pela reação com nucleófilos em produtos de adição, tais como carbamatos, uréias e sulfoniluréias e produtos correspondentes, por exemplo, sulfoniluréias herbicidas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19833007A DE19833007A1 (de) | 1998-07-23 | 1998-07-23 | Verfahren zur Herstellung von 4,6-disubstituierten 2-Isocyanatopyrimidinen und ihre Verwendung als Zwischenprodukte für Wirkstoffsynthesen |
PCT/EP1999/004910 WO2000005220A1 (de) | 1998-07-23 | 1999-07-13 | Verfahren zur herstellung von 4,6-disubstituierten 2-isocyanatopyrimidinen und ihre verwendung als zwischenprodukte für wirkstoffsynthesen |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9912303A true BR9912303A (pt) | 2001-04-17 |
Family
ID=7874943
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9912303-7A BR9912303A (pt) | 1998-07-23 | 1999-07-13 | Processo para a preparação de 2-isocianatopirimidinas 4,5-dissubstituìdas e seu emprego como produtos intermediários para sìnteses de substâncias ativas |
Country Status (23)
Country | Link |
---|---|
US (1) | US6365739B1 (pt) |
EP (1) | EP1097144B1 (pt) |
JP (1) | JP2002521372A (pt) |
KR (1) | KR20010092263A (pt) |
CN (1) | CN1187339C (pt) |
AR (1) | AR019441A1 (pt) |
AT (1) | ATE389639T1 (pt) |
AU (1) | AU751943B2 (pt) |
BR (1) | BR9912303A (pt) |
CA (1) | CA2338349A1 (pt) |
CO (1) | CO5090922A1 (pt) |
CZ (1) | CZ2001248A3 (pt) |
DE (2) | DE19833007A1 (pt) |
HU (1) | HUP0103106A3 (pt) |
ID (1) | ID28958A (pt) |
IL (1) | IL140786A0 (pt) |
MX (1) | MXPA01000820A (pt) |
PL (1) | PL345698A1 (pt) |
RU (1) | RU2224750C2 (pt) |
TR (1) | TR200100184T2 (pt) |
TW (1) | TW520363B (pt) |
WO (1) | WO2000005220A1 (pt) |
ZA (1) | ZA200100519B (pt) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP5468289B2 (ja) * | 2008-04-18 | 2014-04-09 | 石原産業株式会社 | ピリミジン系化合物の製造方法 |
CN106349168A (zh) * | 2016-08-12 | 2017-01-25 | 淮安国瑞化工有限公司 | 磺酰脲类除草剂甲酰胺磺隆中间体的制备方法 |
CN111423385B (zh) * | 2020-05-22 | 2022-02-18 | 北京英力精化技术发展有限公司 | 4,6-二甲氧基-2-((苯氧基羰基)氨基)-嘧啶的精制方法 |
CN114539165A (zh) * | 2022-02-21 | 2022-05-27 | 江苏瑞邦农化股份有限公司 | 一种甲基二磺隆的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1233854B (de) * | 1965-03-03 | 1967-02-09 | Bayer Ag | Verfahren zum Herstellen von Isocyanaten |
US4822402A (en) * | 1985-06-07 | 1989-04-18 | Ishihara Sangyo Kaisha Ltd. | Thiophenesulfonamide compounds, and herbicidal compositions containing them |
IN164880B (pt) * | 1986-01-30 | 1989-06-24 | Ishihara Sangyo Kaisha | |
DE4206145A1 (de) * | 1992-02-28 | 1993-09-02 | Basf Ag | Herbizide n-((pyrimidin-2-yl)aminocarbonyl)benzolfulfonamide |
DE4322726A1 (de) * | 1993-07-08 | 1995-01-12 | Basf Ag | Herbizide N-[(Pyrimidin-2-yl bzw. 1,3,5-Triazin-2-yl)aminocarbonyl]-benzolsulfonamide |
-
1998
- 1998-07-23 DE DE19833007A patent/DE19833007A1/de not_active Withdrawn
-
1999
- 1999-07-13 WO PCT/EP1999/004910 patent/WO2000005220A1/de active IP Right Grant
- 1999-07-13 RU RU2001105095/04A patent/RU2224750C2/ru not_active IP Right Cessation
- 1999-07-13 BR BR9912303-7A patent/BR9912303A/pt not_active Application Discontinuation
- 1999-07-13 TR TR2001/00184T patent/TR200100184T2/xx unknown
- 1999-07-13 EP EP99932871A patent/EP1097144B1/de not_active Expired - Lifetime
- 1999-07-13 CA CA002338349A patent/CA2338349A1/en not_active Abandoned
- 1999-07-13 CN CNB998091618A patent/CN1187339C/zh not_active Expired - Fee Related
- 1999-07-13 ID IDW20010142A patent/ID28958A/id unknown
- 1999-07-13 MX MXPA01000820A patent/MXPA01000820A/es unknown
- 1999-07-13 DE DE59914698T patent/DE59914698D1/de not_active Expired - Fee Related
- 1999-07-13 JP JP2000561176A patent/JP2002521372A/ja not_active Abandoned
- 1999-07-13 AT AT99932871T patent/ATE389639T1/de not_active IP Right Cessation
- 1999-07-13 KR KR1020017000843A patent/KR20010092263A/ko not_active Application Discontinuation
- 1999-07-13 CZ CZ2001248A patent/CZ2001248A3/cs unknown
- 1999-07-13 IL IL14078699A patent/IL140786A0/xx not_active IP Right Cessation
- 1999-07-13 PL PL99345698A patent/PL345698A1/xx not_active Application Discontinuation
- 1999-07-13 HU HU0103106A patent/HUP0103106A3/hu unknown
- 1999-07-13 AU AU49099/99A patent/AU751943B2/en not_active Ceased
- 1999-07-21 US US09/358,297 patent/US6365739B1/en not_active Expired - Fee Related
- 1999-07-21 TW TW088112405A patent/TW520363B/zh not_active IP Right Cessation
- 1999-07-21 AR ARP990103578A patent/AR019441A1/es not_active Application Discontinuation
- 1999-07-21 CO CO99045931A patent/CO5090922A1/es unknown
-
2001
- 2001-01-18 ZA ZA200100519A patent/ZA200100519B/en unknown
Also Published As
Publication number | Publication date |
---|---|
CN1311782A (zh) | 2001-09-05 |
AU751943B2 (en) | 2002-09-05 |
EP1097144B1 (de) | 2008-03-19 |
AU4909999A (en) | 2000-02-14 |
ID28958A (id) | 2001-07-19 |
KR20010092263A (ko) | 2001-10-24 |
AR019441A1 (es) | 2002-02-20 |
HUP0103106A2 (hu) | 2001-12-28 |
HUP0103106A3 (en) | 2002-12-28 |
DE59914698D1 (de) | 2008-04-30 |
ZA200100519B (en) | 2001-09-19 |
US6365739B1 (en) | 2002-04-02 |
ATE389639T1 (de) | 2008-04-15 |
DE19833007A1 (de) | 2000-02-03 |
JP2002521372A (ja) | 2002-07-16 |
RU2224750C2 (ru) | 2004-02-27 |
CZ2001248A3 (cs) | 2001-08-15 |
WO2000005220A1 (de) | 2000-02-03 |
CN1187339C (zh) | 2005-02-02 |
CO5090922A1 (es) | 2001-10-30 |
TW520363B (en) | 2003-02-11 |
TR200100184T2 (tr) | 2001-05-21 |
CA2338349A1 (en) | 2000-02-03 |
MXPA01000820A (es) | 2002-04-08 |
IL140786A0 (en) | 2002-02-10 |
PL345698A1 (en) | 2002-01-02 |
EP1097144A1 (de) | 2001-05-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B06A | Patent application procedure suspended [chapter 6.1 patent gazette] | ||
B11B | Dismissal acc. art. 36, par 1 of ipl - no reply within 90 days to fullfil the necessary requirements | ||
B25D | Requested change of name of applicant approved |
Owner name: BAYER CROPSCIENCE GMBH (DE) Free format text: ALTERADO DE: AVENTIS CROPSCIENCE GMBH |
|
B25A | Requested transfer of rights approved |
Owner name: BAYER CROPSCIENCE AG (DE) Free format text: TRANSFERIDO POR FUSAO DE: BAYER CROPSCIENCE GMBH |