BR112013024378A2 - novos derivados de pirimidina - Google Patents

novos derivados de pirimidina

Info

Publication number
BR112013024378A2
BR112013024378A2 BR112013024378A BR112013024378A BR112013024378A2 BR 112013024378 A2 BR112013024378 A2 BR 112013024378A2 BR 112013024378 A BR112013024378 A BR 112013024378A BR 112013024378 A BR112013024378 A BR 112013024378A BR 112013024378 A2 BR112013024378 A2 BR 112013024378A2
Authority
BR
Brazil
Prior art keywords
pyrimidine derivatives
new pyrimidine
new
derivatives
pyrimidine
Prior art date
Application number
BR112013024378A
Other languages
English (en)
Inventor
Emma Dahltedt
Marita Hogberg
Olof Smitt
Tommy Johansson
Original Assignee
Chemilia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP11159589A external-priority patent/EP2502924A1/en
Application filed by Chemilia Ab filed Critical Chemilia Ab
Publication of BR112013024378A2 publication Critical patent/BR112013024378A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
BR112013024378A 2011-03-24 2012-03-23 novos derivados de pirimidina BR112013024378A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11159589A EP2502924A1 (en) 2011-03-24 2011-03-24 Novel pyrimidine derivatives
EP11189572 2011-11-17
PCT/EP2012/055216 WO2012127032A1 (en) 2011-03-24 2012-03-23 Novel pyrimidine derivatives

Publications (1)

Publication Number Publication Date
BR112013024378A2 true BR112013024378A2 (pt) 2016-12-13

Family

ID=45876788

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013024378A BR112013024378A2 (pt) 2011-03-24 2012-03-23 novos derivados de pirimidina

Country Status (12)

Country Link
US (1) US9006241B2 (pt)
EP (1) EP2688883B1 (pt)
JP (1) JP5886411B2 (pt)
KR (1) KR20140006048A (pt)
AU (1) AU2012230229A1 (pt)
BR (1) BR112013024378A2 (pt)
CA (1) CA2830129C (pt)
DK (1) DK2688883T3 (pt)
ES (1) ES2587864T3 (pt)
MX (1) MX2013010898A (pt)
RU (1) RU2013147417A (pt)
WO (1) WO2012127032A1 (pt)

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EP2711365A1 (en) * 2012-09-21 2014-03-26 Chemilia AB 4-Indazolylamino-2-(2-(indol-3-yl)ethyl)aminopyrimidines useful for the treatment of cancer
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BR112019024109A2 (pt) 2017-05-18 2020-06-02 Idorsia Pharmaceuticals Ltd Composto, composição farmacêutica, uso de um composto ou um sal farmaceuticamente aceitável do mesmo, método de modulação de uma resposta imune em um indivíduo com um tumor, e, método de profilaxia ou tratamento
PL3625224T3 (pl) 2017-05-18 2022-01-10 Idorsia Pharmaceuticals Ltd Pochodne n-podstawionego indolu
KR102612140B1 (ko) 2017-05-18 2023-12-08 이도르시아 파마슈티컬스 리미티드 피리미딘 유도체
CA3060394A1 (en) 2017-05-18 2018-11-22 Idorsia Pharmaceuticals Ltd Pyrimidine derivatives as pge2 receptor modulators
JP7093791B2 (ja) 2017-05-18 2022-06-30 イドーシア ファーマシューティカルズ リミテッド Ｐｇｅ２レセプター調節剤としてのベンゾフラン及びベンゾチオフェン誘導体
CN109020957B (zh) * 2017-06-12 2023-01-13 南京天印健华医药科技有限公司 作为mnk抑制剂的杂环化合物
EP3773592A4 (en) * 2018-04-05 2022-02-23 Noviga Research AB NOVEL COMBINATIONS OF A TUBULIN POLYMERIZATION INHIBITOR AND A POLY(ADP-RIBOSE)POLYMERASE (PARP) INHIBITOR FOR USE IN THE TREATMENT OF CANCER
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RU2013147417A (ru) 2015-04-27
MX2013010898A (es) 2013-12-06
WO2012127032A1 (en) 2012-09-27
DK2688883T3 (en) 2016-09-05
CN103619835A (zh) 2014-03-05
AU2012230229A1 (en) 2013-10-10
EP2688883B1 (en) 2016-05-18
KR20140006048A (ko) 2014-01-15
CA2830129A1 (en) 2012-09-27
US9006241B2 (en) 2015-04-14
ES2587864T3 (es) 2016-10-27
JP2014508795A (ja) 2014-04-10
EP2688883A1 (en) 2014-01-29
US20140045845A1 (en) 2014-02-13
JP5886411B2 (ja) 2016-03-16

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