BR112012013305A2 - processos para a preparação de ácido poliglutâmico - Google Patents

processos para a preparação de ácido poliglutâmico

Info

Publication number
BR112012013305A2
BR112012013305A2 BR112012013305A BR112012013305A BR112012013305A2 BR 112012013305 A2 BR112012013305 A2 BR 112012013305A2 BR 112012013305 A BR112012013305 A BR 112012013305A BR 112012013305 A BR112012013305 A BR 112012013305A BR 112012013305 A2 BR112012013305 A2 BR 112012013305A2
Authority
BR
Brazil
Prior art keywords
processes
polyglutamic acid
preparation
disclosed
obtaining
Prior art date
Application number
BR112012013305A
Other languages
English (en)
Inventor
Hai Wang
Wendy Dianne Taylor
Original Assignee
Nitto Denko Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nitto Denko Corp filed Critical Nitto Denko Corp
Publication of BR112012013305A2 publication Critical patent/BR112012013305A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/12—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by hydrolysis, i.e. solvolysis in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polyamides (AREA)

Abstract

processos para a preparação de ácido poliglutâmico. são divulgados aqui processos para a obtenção de ácido poliglutâmico. os processos divulgados aqui são processos controlados para a obtenção de ácido poliglutâmico, com um peso molecular médio ponderal desejado.
BR112012013305A 2009-12-16 2010-12-14 processos para a preparação de ácido poliglutâmico BR112012013305A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28712909P 2009-12-16 2009-12-16
PCT/US2010/060327 WO2011075483A1 (en) 2009-12-16 2010-12-14 Controlled synthesis of polyglutamic acid

Publications (1)

Publication Number Publication Date
BR112012013305A2 true BR112012013305A2 (pt) 2016-03-01

Family

ID=44143670

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112012013305A BR112012013305A2 (pt) 2009-12-16 2010-12-14 processos para a preparação de ácido poliglutâmico

Country Status (11)

Country Link
US (1) US20110144315A1 (pt)
EP (1) EP2513133A4 (pt)
JP (1) JP2013514443A (pt)
KR (1) KR20120094061A (pt)
CN (1) CN102666566A (pt)
AU (1) AU2010331986A1 (pt)
BR (1) BR112012013305A2 (pt)
CA (1) CA2782410A1 (pt)
MX (1) MX2012006834A (pt)
TW (1) TW201124447A (pt)
WO (1) WO2011075483A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602006007177D1 (de) 2005-12-05 2009-07-16 Nitto Denko Corp Polyglutamat-aminosäure-konjugate und verfahren
EP2155255B1 (en) 2007-05-09 2013-08-14 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
RU2011117935A (ru) * 2008-10-15 2012-11-27 Нитто Денко Корпорейшн Способ получения конъюгатов полиглутаматов
JP6262201B2 (ja) 2012-04-12 2018-01-17 日東電工株式会社 コポリマー結合体
WO2013169337A1 (en) 2012-05-07 2013-11-14 Nitto Denko Corporation Polymer conjugates with a linker
CN105296558B (zh) * 2015-11-18 2018-11-20 广东迪美生物技术有限公司 一种基于分段发酵生产低分子量γ-聚谷氨酸的方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1253863B (de) * 1962-03-27 1967-11-09 Ajinomoto Kk Verfahren zum Herstellen von Fasern, bestehend aus einem Gemisch von Regeneratcellulose und einer polymeren Aminosaeure
SE8304361D0 (sv) * 1983-08-10 1983-08-10 Ferrosan Ab Novel 1-acylpiperazine derivatives novel 1-acylpiperazine derivatives
DE3575130D1 (de) * 1984-05-12 1990-02-08 Fisons Plc Antiinflammatorische 1,n-diarylpyrazol-3-amine, deren zusammensetzungen und verfahren zu deren herstellung.
JP2759716B2 (ja) * 1991-03-28 1998-05-28 明治製菓株式会社 ポリ−γ−グルタミン酸の分子量制御法
US5981507A (en) * 1995-12-14 1999-11-09 Advanced Magnetics, Inc. Polymeric carriers linked to nucleotide analogues via a phosphoramide bond
SE9703379D0 (sv) * 1997-09-18 1997-09-18 Astra Ab New compounds
US7090845B2 (en) * 1998-05-13 2006-08-15 Genentech, Inc. Diagnosis and treatment of hepatic disorders
RU2002128610A (ru) * 2000-03-17 2004-03-27 Селл Терапьютикс, Инк. (Us) Композиция конъюгатов полиглутаминовой кислоты с камптотецином (варианты) и способ ее получения (варианты), фармацевтическая композиция (варианты) и способ лечения лейкоза или плотной опухоли
WO2004028548A2 (en) * 2002-09-26 2004-04-08 Carbomer, Inc. Inhibitors of the nitrix oxide synthase iii (nos iii) as neuroprotective agents
US20050276783A1 (en) * 2004-06-10 2005-12-15 Ernest Giralt Lledo Polypeptides with the capacity to entrap drugs and release them in a controlled way
TWI317291B (en) * 2005-01-12 2009-11-21 Tung Hai Biotechnology Corp Polyglutamic acid (gamma;-pga, h form), y-polyglutamates and gamma-polyglutamate hydrogels for use as super moisturizers in cosmetic and personal care products
US20080051603A1 (en) * 2006-06-15 2008-02-28 Cell Therapeutics, Inc. Process for the preparation of poly-alpha-glutamic acid and derivatives thereof
CA2656077C (en) * 2006-06-15 2014-12-09 Marc Mckennon A process for the preparation of poly-alpha-glutamic acid and derivatives thereof
EP1867657A1 (en) * 2006-06-15 2007-12-19 Cell Therapeutics Europe S.R.L. Process for the preparation of poly-a-glutamic acid and derivatives thereof
US20080181852A1 (en) * 2007-01-29 2008-07-31 Nitto Denko Corporation Multi-functional Drug Carriers
EP2144631A2 (en) * 2007-04-10 2010-01-20 Nitto Denko Corporation Multi-functional polyglutamate drug carriers
EP2155255B1 (en) * 2007-05-09 2013-08-14 Nitto Denko Corporation Compositions that include a hydrophobic compound and a polyamino acid conjugate
CN101730549B (zh) * 2007-05-09 2015-12-09 日东电工株式会社 与铂类药物结合的聚合物
CN101707869A (zh) * 2007-05-09 2010-05-12 日东电工株式会社 具有多种药物的聚谷氨酸盐结合物和聚谷氨酸盐-氨基酸结合物
CN104096236A (zh) * 2008-03-06 2014-10-15 日东电工株式会社 用于治疗癌症的聚合物紫杉醇结合物和方法
RU2011117935A (ru) * 2008-10-15 2012-11-27 Нитто Денко Корпорейшн Способ получения конъюгатов полиглутаматов

Also Published As

Publication number Publication date
EP2513133A4 (en) 2014-07-02
EP2513133A1 (en) 2012-10-24
JP2013514443A (ja) 2013-04-25
TW201124447A (en) 2011-07-16
AU2010331986A1 (en) 2012-05-31
CN102666566A (zh) 2012-09-12
US20110144315A1 (en) 2011-06-16
CA2782410A1 (en) 2011-06-23
MX2012006834A (es) 2012-07-10
WO2011075483A1 (en) 2011-06-23
KR20120094061A (ko) 2012-08-23

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]
B350 Update of information on the portal [chapter 15.35 patent gazette]