ATE418536T1 - Neue immunotherapeutische mittel und deren verwendung in der reduzierung von cytokinenspiegel - Google Patents

Neue immunotherapeutische mittel und deren verwendung in der reduzierung von cytokinenspiegel

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Publication number
ATE418536T1
ATE418536T1 AT03002806T AT03002806T ATE418536T1 AT E418536 T1 ATE418536 T1 AT E418536T1 AT 03002806 T AT03002806 T AT 03002806T AT 03002806 T AT03002806 T AT 03002806T AT E418536 T1 ATE418536 T1 AT E418536T1
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Austria
Prior art keywords
carbon atoms
alkyl
substituted
amino
cyano
Prior art date
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AT03002806T
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English (en)
Inventor
George W Muller
Mary Shire
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Celgene Corp
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Publication of ATE418536T1 publication Critical patent/ATE418536T1/de

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    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
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    • C07C255/32Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/37Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by etherified hydroxy groups
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AT03002806T 1996-08-12 1997-08-11 Neue immunotherapeutische mittel und deren verwendung in der reduzierung von cytokinenspiegel ATE418536T1 (de)

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AT03002806T ATE418536T1 (de) 1996-08-12 1997-08-11 Neue immunotherapeutische mittel und deren verwendung in der reduzierung von cytokinenspiegel
AT97936479T ATE236872T1 (de) 1996-08-12 1997-08-11 Immunotherapeutische mittel und ihre anwendung in der reduzierung der cytokininwerte

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EP (2) EP0918746B1 (de)
JP (2) JP4214537B2 (de)
KR (2) KR100539031B1 (de)
CN (1) CN1263731C (de)
AT (2) ATE418536T1 (de)
AU (1) AU729247B2 (de)
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CZ (1) CZ299810B6 (de)
DE (2) DE69739181D1 (de)
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US6130226A (en) 2000-10-10
DE69739181D1 (de) 2009-02-05
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HUP9904569A2 (hu) 2000-05-28
EP0918746A1 (de) 1999-06-02
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