ATE259796T1 - Respiratorisches syncytialvirus replikation inhibitoren - Google Patents

Respiratorisches syncytialvirus replikation inhibitoren

Info

Publication number: ATE259796T1
Authority: AT; Austria
Prior art keywords: replication inhibitors; syncytialvirus; respiratory; respiratory syncytialvirus; replication
Prior art date: 1999-06-28

Application number

AT00936899T

Other languages

English (en)

Inventor

Frans Eduard Janssens

Jean Fernand Armand Lacrampe

Jerome Emile G Jans Guillemont

Marc Gaston Venet

Koenraad Jozef Lodewij Andries

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-06-28

Filing date

2000-06-20

Publication date

2004-03-15

2000-06-20 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2004-03-15 Application granted granted Critical

2004-03-15 Publication of ATE259796T1 publication Critical patent/ATE259796T1/de

Links

241000725643 Respiratory syncytial virus Species 0.000 title 1
239000003112 inhibitor Substances 0.000 title 1
230000010076 replication Effects 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

AT00936899T 1999-06-28 2000-06-20 Respiratorisches syncytialvirus replikation inhibitoren ATE259796T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99202089		1999-06-28
PCT/EP2000/005677 WO2001000615A1 (en)	1999-06-28	2000-06-20	Respiratory syncytial virus replication inhibitors

Publications (1)

Publication Number	Publication Date
ATE259796T1 true ATE259796T1 (de)	2004-03-15

Family

ID=8240374

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
AT03102464T ATE356121T1 (de)	1999-06-28	2000-06-20	Hemmer des respiratorischen syncytial virus
AT00936899T ATE259796T1 (de)	1999-06-28	2000-06-20	Respiratorisches syncytialvirus replikation inhibitoren

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT03102464T ATE356121T1 (de)	1999-06-28	2000-06-20	Hemmer des respiratorischen syncytial virus

Country Status (34)

Country	Link
US (2)	US7071192B1 (de)
EP (2)	EP1196410B1 (de)
JP (1)	JP2003503403A (de)
KR (1)	KR100731273B1 (de)
CN (1)	CN1171887C (de)
AR (1)	AR024495A1 (de)
AT (2)	ATE356121T1 (de)
AU (1)	AU774829B2 (de)
BG (1)	BG65373B1 (de)
BR (1)	BR0011997A (de)
CA (1)	CA2376785A1 (de)
CZ (1)	CZ20014573A3 (de)
DE (2)	DE60033859T2 (de)
DK (1)	DK1196410T3 (de)
EA (1)	EA004746B1 (de)
EE (1)	EE04592B1 (de)
ES (2)	ES2283716T3 (de)
HK (1)	HK1045998B (de)
HR (2)	HRP20010934A2 (de)
HU (1)	HUP0201789A3 (de)
IL (2)	IL147328A0 (de)
MX (1)	MXPA02000117A (de)
MY (1)	MY129810A (de)
NO (1)	NO321599B1 (de)
NZ (1)	NZ515392A (de)
PL (1)	PL200694B1 (de)
PT (1)	PT1196410E (de)
SI (1)	SI1196410T1 (de)
SK (1)	SK18952001A3 (de)
TR (2)	TR200103805T2 (de)
TW (1)	TWI267513B (de)
UA (1)	UA75866C2 (de)
WO (1)	WO2001000615A1 (de)
ZA (1)	ZA200110473B (de)

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US6489338B2 (en)	2000-06-13	2002-12-03	Bristol-Myers Squibb Company	Imidazopyridine and imidazopyrimidine antiviral agents
US6506738B1 (en)	2000-09-27	2003-01-14	Bristol-Myers Squibb Company	Benzimidazolone antiviral agents
WO2002048147A2 (en)	2000-12-15	2002-06-20	Glaxo Group Limited	Pyrazolopyridines
AU2002239348A1 (en)	2000-12-15	2002-06-24	Glaxo Group Limited	Pyrazolopyridine derivatives
US6774134B2 (en)	2000-12-20	2004-08-10	Bristol-Myers Squibb Company	Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
AU2002248531A1 (en)	2001-03-08	2002-09-24	Smithkline Beecham Corporation	Pyrazolopyriadine derivatives
US7034030B2 (en)	2001-03-30	2006-04-25	Smithkline Beecham Corporation	Pyralopyridines, process for their preparation and use as therapeutic compounds
ATE332301T1 (de)	2001-04-10	2006-07-15	Smithkline Beecham Corp	Antivirale pyrazolopyridin verbindungen
ES2242028T3 (es)	2001-04-27	2005-11-01	Smithkline Beecham Corporation	Derivados de pirazolo(1,5-a)piridina.
US7030150B2 (en) *	2001-05-11	2006-04-18	Trimeris, Inc.	Benzimidazole compounds and antiviral uses thereof
HUP0400266A2 (hu)	2001-06-21	2004-08-30	Smithkline Beecham Corp.	Imidazo[1,2-a]piridin-származékok, ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk herpeszvírus-fertőzések megelőzésére vagy kezelésére
JP2005508955A (ja)	2001-10-05	2005-04-07	スミスクラインビーチャムコーポレーション	ヘルペスウイルス感染の治療で使用されるためのイミダゾ−ピリジン誘導体
US6919331B2 (en)	2001-12-10	2005-07-19	Bristol-Myers Squibb Company	Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
AU2002357740A1 (en)	2001-12-11	2003-06-23	Smithkline Beecham Corporation	Pyrazolo-pyridine derivatives as antiherpes agents
US7244847B2 (en) *	2002-02-06	2007-07-17	Isis Pharmaceuticals, Inc.	Benzimidazole compounds
WO2004014316A2 (en)	2002-08-09	2004-02-19	Viropharma Incorporated	Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
AU2003258177A1 (en)	2002-08-09	2004-02-25	Viropharma Incorporated	Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
WO2004033454A1 (en)	2002-10-03	2004-04-22	Smithkline Beecham Corporation	Therapeutic compounds based on pyrazolopyridine derivatives
CA2541618C (en) *	2003-10-30	2011-12-13	Boehringer Ingelheim (Canada) Ltd.	Rsv polymerase inhibitors
WO2005058874A1 (en) *	2003-12-18	2005-06-30	Tibotec Pharmaceuticals Ltd.	5- or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication
AR046771A1 (es) *	2003-12-18	2005-12-21	Tibotec Pharm Ltd	Derivados piperidina-amino-bencimidazol como inhibidores de la replicacion del virus sincitial respiratorio
CN1894236B (zh) *	2003-12-18	2011-08-17	泰博特克药品有限公司	作为呼吸道合胞病毒复制抑制剂的氨基-苯并咪唑类衍生物
ES2326813T3 (es) *	2003-12-18	2009-10-20	Tibotec Pharmaceuticals Ltd.	Derivados de amino-bencimidazoles como inhibidores de la replicacion del virus respiratorio sincitial.
US8044073B2 (en)	2003-12-18	2011-10-25	Tibotec Pharmaceuticals	Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication
AR046959A1 (es)	2003-12-18	2006-01-04	Tibotec Pharm Ltd	Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
CA2600507C (en) *	2005-03-17	2013-10-22	Tibotec Pharmaceuticals Ltd.	1,3-dihydro-benzimidazol-2-ylidene amines as inhibitors of respiratory syncytial virus replication
CA2612263C (en)	2005-06-20	2015-04-14	Tibotec Pharmaceuticals Ltd.	1-(2-amino-3-(substituted alkyl)-3h-benzimidazolylmethyl)-3-subtituted-1,3-dihydro-benzoimidazol-2-ones with activity on respiratory syncytial virus
AU2006260970B2 (en) *	2005-06-20	2012-07-05	Janssen Sciences Ireland Uc	Heterocyclylaminoalkyl substituted benzimidazoles
CL2008001003A1 (es)	2007-04-11	2008-10-17	Actelion Pharmaceuticals Ltd	Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
WO2010045276A2 (en) *	2008-10-16	2010-04-22	Cara Therapeutics, Inc.	Azabenzimidazolones
JP5487692B2 (ja)	2009-04-10	2014-05-07	国立大学法人京都大学	複素環骨格を有する化合物および該化合物を不斉触媒として用いる光学活性化合物の製造方法
US8993604B2 (en)	2009-06-30	2015-03-31	Siga Technologies, Inc.	Treatment and prevention of dengue virus infections
AU2010266570A1 (en) *	2009-06-30	2012-01-19	Siga Technologies, Inc.	Treatment and prevention of Dengue virus infections
BR112014001018A2 (pt)	2011-07-15	2017-01-10	Shionogi & Co	derivado de azabenzimidazol tendo atividade de ativação de ampk
AU2013305759C1 (en)	2012-08-23	2018-01-18	Janssen Biopharma, Inc.	Compounds for the treatment of paramoxyvirus viral infections
JP2016079168A (ja)	2014-10-17	2016-05-16	塩野義製薬株式会社	９員縮合環誘導体

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2000
- 2000-06-20 JP JP2001507023A patent/JP2003503403A/ja not_active Withdrawn
- 2000-06-20 AT AT03102464T patent/ATE356121T1/de not_active IP Right Cessation
- 2000-06-20 KR KR1020017015284A patent/KR100731273B1/ko not_active IP Right Cessation
- 2000-06-20 ES ES03102464T patent/ES2283716T3/es not_active Expired - Lifetime
- 2000-06-20 SI SI200030358T patent/SI1196410T1/xx unknown
- 2000-06-20 AT AT00936899T patent/ATE259796T1/de not_active IP Right Cessation
- 2000-06-20 BR BR0011997-0A patent/BR0011997A/pt not_active Application Discontinuation
- 2000-06-20 WO PCT/EP2000/005677 patent/WO2001000615A1/en active Application Filing
- 2000-06-20 DK DK00936899T patent/DK1196410T3/da active
- 2000-06-20 US US10/019,376 patent/US7071192B1/en not_active Expired - Fee Related
- 2000-06-20 EP EP00936899A patent/EP1196410B1/de not_active Expired - Lifetime
- 2000-06-20 CA CA002376785A patent/CA2376785A1/en not_active Abandoned
- 2000-06-20 TR TR2001/03805T patent/TR200103805T2/xx unknown
- 2000-06-20 HU HU0201789A patent/HUP0201789A3/hu unknown
- 2000-06-20 PL PL352385A patent/PL200694B1/pl not_active IP Right Cessation
- 2000-06-20 EP EP03102464A patent/EP1400519B1/de not_active Expired - Lifetime
- 2000-06-20 PT PT00936899T patent/PT1196410E/pt unknown
- 2000-06-20 DE DE60033859T patent/DE60033859T2/de not_active Expired - Fee Related
- 2000-06-20 AU AU52222/00A patent/AU774829B2/en not_active Ceased
- 2000-06-20 NZ NZ515392A patent/NZ515392A/xx unknown
- 2000-06-20 UA UA2002010361A patent/UA75866C2/uk unknown
- 2000-06-20 EE EEP200100694A patent/EE04592B1/xx not_active IP Right Cessation
- 2000-06-20 SK SK1895-2001A patent/SK18952001A3/sk unknown
- 2000-06-20 TR TR2005/00707T patent/TR200500707T2/xx unknown
- 2000-06-20 DE DE60008382T patent/DE60008382T2/de not_active Expired - Fee Related
- 2000-06-20 ES ES00936899T patent/ES2215670T3/es not_active Expired - Lifetime
- 2000-06-20 EA EA200200086A patent/EA004746B1/ru not_active IP Right Cessation
- 2000-06-20 MX MXPA02000117A patent/MXPA02000117A/es active IP Right Grant
- 2000-06-20 CZ CZ20014573A patent/CZ20014573A3/cs unknown
- 2000-06-20 CN CNB008095302A patent/CN1171887C/zh not_active Expired - Fee Related
- 2000-06-20 IL IL14732800A patent/IL147328A0/xx active IP Right Grant
- 2000-06-26 TW TW089112479A patent/TWI267513B/zh not_active IP Right Cessation
- 2000-06-27 MY MYPI20002914A patent/MY129810A/en unknown
- 2000-06-27 AR ARP000103222A patent/AR024495A1/es unknown
2001
- 2001-12-19 HR HR20010934A patent/HRP20010934A2/hr not_active Application Discontinuation
- 2001-12-20 ZA ZA200110473A patent/ZA200110473B/xx unknown
- 2001-12-26 IL IL147328A patent/IL147328A/en not_active IP Right Cessation
- 2001-12-27 NO NO20016370A patent/NO321599B1/no unknown
2002
- 2002-01-08 BG BG106288A patent/BG65373B1/bg unknown
- 2002-10-21 HK HK02107623.8A patent/HK1045998B/zh not_active IP Right Cessation
2005
- 2005-10-11 US US11/247,392 patent/US7407969B2/en not_active Expired - Fee Related
2008
- 2008-08-12 HR HR20080390A patent/HRP20080390A2/xx not_active Application Discontinuation

Also Published As

Publication number	Publication date
WO2001000615A1 (en)	2001-01-04
HRP20010934A2 (en)	2003-06-30
HUP0201789A2 (hu)	2002-11-28
IL147328A (en)	2007-06-03
JP2003503403A (ja)	2003-01-28
NO20016370D0 (no)	2001-12-27
DE60033859D1 (de)	2007-04-19
PT1196410E (pt)	2004-07-30
PL352385A1 (en)	2003-08-25
CN1171887C (zh)	2004-10-20
BR0011997A (pt)	2002-03-05
EE200100694A (et)	2003-02-17
HK1045998A1 (en)	2002-12-20
EA200200086A1 (ru)	2002-06-27
DE60008382D1 (en)	2004-03-25
US7071192B1 (en)	2006-07-04
DE60033859T2 (de)	2007-11-08
SK18952001A3 (sk)	2002-11-06
EP1196410A1 (de)	2002-04-17
EP1196410B1 (de)	2004-02-18
TR200500707T2 (tr)	2005-04-21
DE60008382T2 (de)	2004-12-02
NO321599B1 (no)	2006-06-06
ZA200110473B (en)	2003-03-20
CN1358182A (zh)	2002-07-10
IL147328A0 (en)	2002-08-14
US7407969B2 (en)	2008-08-05
EE04592B1 (et)	2006-02-15
TWI267513B (en)	2006-12-01
ES2283716T3 (es)	2007-11-01
CZ20014573A3 (cs)	2002-05-15
CA2376785A1 (en)	2001-01-04
DK1196410T3 (da)	2004-06-28
AR024495A1 (es)	2002-10-02
BG106288A (en)	2002-10-31
MY129810A (en)	2007-05-31
UA75866C2 (en)	2006-06-15
HK1045998B (zh)	2005-06-03
SI1196410T1 (en)	2004-08-31
ES2215670T3 (es)	2004-10-16
AU5222200A (en)	2001-01-31
ATE356121T1 (de)	2007-03-15
TR200103805T2 (tr)	2002-06-21
WO2001000615A8 (en)	2002-01-10
US20060058309A1 (en)	2006-03-16
MXPA02000117A (es)	2002-07-02
EP1400519B1 (de)	2007-03-07
BG65373B1 (bg)	2008-04-30
NZ515392A (en)	2004-03-26
EA004746B1 (ru)	2004-08-26
EP1400519A1 (de)	2004-03-24
HUP0201789A3 (en)	2003-12-29
NO20016370L (no)	2001-12-27
KR20020000815A (ko)	2002-01-05
KR100731273B1 (ko)	2007-06-21
PL200694B1 (pl)	2009-01-30
HRP20080390A2 (en)	2008-12-31
AU774829B2 (en)	2004-07-08

Legal Events

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2004-11-15

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Publication of translation of european patent specification

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2010-03-15

REN

Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
ATE258928T1 (de)	2004-02-15	Respiratorisches syncytialvirus replikation inhibitoren
ATE259796T1 (de)	2004-03-15	Respiratorisches syncytialvirus replikation inhibitoren
PT1196408E (pt)	2005-01-31	Inibidores da replicacao do virus sincicial respiratorio
NO20022922D0 (no)	2002-06-18	Inhalasjonsanordning
PT1226136E (pt)	2005-04-29	Inibidores da tirosina quinase
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DK1272488T3 (da)	2006-07-17	Tri-aryl-substitueret ethan-PDE4-inhibitorer
NO20022921D0 (no)	2002-06-18	Inhalasjonsanordning
DE60117455T8 (de)	2007-02-01	Sicherungseinheit
PT1189929E (pt)	2003-12-31	Inibidores do factor viia
DE60139831D1 (de)	2009-10-22	Sicherung
PT1339695E (pt)	2006-08-31	Inibidores da farnesiltransferase
FR2816398B3 (fr)	2002-10-11	Fronde perfectionnee
ES1046532Y (es)	2001-06-01	Inhalador perfeccionado
DK199900440U3 (da)	2000-02-11	Røggiver
DK199900281U3 (da)	1999-10-22	Røggiver
DK1267974T3 (da)	2005-08-01	Inhalationsapparat
ES1047372Y (es)	2001-09-01	Pararrayos perfeccionado
IT1314780B1 (it)	2003-01-16	Fucile perfezionato
ES1046387Y (es)	2001-06-01	Rodapie perfeccionado
SE9903429D0 (sv)	1999-09-22	Inhalation device
SE9903428D0 (sv)	1999-09-22	Inhalation device
SE9903427D0 (sv)	1999-09-22	Inhalation device
SE9903426D0 (sv)	1999-09-22	Inhalation device
SE9902671D0 (sv)	1999-07-12	Inhalation device