ATA414478A - Verfahren zur herstellung neuer 3-(pyrazol-1- yl)-pyridazin-derivate und der physiologisch vertraeglichen saeureadditions-salze dieser verbindungen - Google Patents

Verfahren zur herstellung neuer 3-(pyrazol-1- yl)-pyridazin-derivate und der physiologisch vertraeglichen saeureadditions-salze dieser verbindungen

Info

Publication number
ATA414478A
ATA414478A AT414478A AT414478A ATA414478A AT A414478 A ATA414478 A AT A414478A AT 414478 A AT414478 A AT 414478A AT 414478 A AT414478 A AT 414478A AT A414478 A ATA414478 A AT A414478A
Authority
AT
Austria
Prior art keywords
pyrazol
compounds
preparation
new
acid addition
Prior art date
Application number
AT414478A
Other languages
English (en)
Other versions
AT357548B (de
Inventor
Geza Dr Szilagyi
Endre Dr Kasztreiner
Laszlo Dr Tadros
Edit Dr Kosa
Laszlo Jaszlits
Gyoergy Dr Cseh
Andras Divald
Pal Dr Tolnay
Sandor Dr Elek
Istvan Dr Elekes
Istvan Dr Polgari
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ATA414478A publication Critical patent/ATA414478A/de
Application granted granted Critical
Publication of AT357548B publication Critical patent/AT357548B/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT414478A 1977-06-13 1978-06-07 Verfahren zur herstellung neuer 3-(pyrazol-1- yl)-pyridazin-derivate und der physiologisch vertraeglichen saeureadditions-salze dieser verbindungen AT357548B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU77GO1373A HU175471B (hu) 1977-06-13 1977-06-13 Sposob poluchenija novykh proizvodnykh 3-skobka-1-pirazolil-skobka zakryta-piridazina

Publications (2)

Publication Number Publication Date
ATA414478A true ATA414478A (de) 1979-12-15
AT357548B AT357548B (de) 1980-07-10

Family

ID=10996834

Family Applications (1)

Application Number Title Priority Date Filing Date
AT414478A AT357548B (de) 1977-06-13 1978-06-07 Verfahren zur herstellung neuer 3-(pyrazol-1- yl)-pyridazin-derivate und der physiologisch vertraeglichen saeureadditions-salze dieser verbindungen

Country Status (25)

Country Link
US (1) US4251658A (de)
JP (1) JPS5416487A (de)
AT (1) AT357548B (de)
AU (1) AU521394B2 (de)
BE (1) BE867967A (de)
BG (1) BG28709A3 (de)
CA (1) CA1095912A (de)
CH (1) CH638202A5 (de)
CS (1) CS204029B2 (de)
DD (1) DD140043A5 (de)
DE (1) DE2825906A1 (de)
DK (1) DK263078A (de)
ES (1) ES470750A1 (de)
FI (1) FI64156C (de)
FR (1) FR2394542A1 (de)
GB (1) GB1603958A (de)
HU (1) HU175471B (de)
IL (1) IL54816A (de)
IT (1) IT1098216B (de)
NL (1) NL7806380A (de)
NO (1) NO149210C (de)
PL (1) PL111252B1 (de)
SE (1) SE437517B (de)
SU (2) SU797577A3 (de)
YU (1) YU140078A (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU176100B (en) * 1977-10-25 1980-12-28 Gyogyszerkutato Intezet Process for preparing new 3-/1-pyrazolyl/-pyridazine derivatives
DE2935359A1 (de) * 1979-09-01 1981-03-26 Basf Ag, 67063 Ludwigshafen 6-imidazolyl-3-hydrazino-pyridazine
DE3130251A1 (de) * 1981-07-31 1983-02-17 A. Nattermann & Cie GmbH, 5000 Köln 6-(4-((omega)-(1-imidazolyl)-alkyl)-phenyl)-3-oxo -2,3,4,5-tetrahydro-pyridazine und deren saeureadditionssalze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4353905A (en) * 1981-09-17 1982-10-12 Warner-Lambert Company Substituted 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and 6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones
US4590194A (en) * 1981-10-05 1986-05-20 Sterling Drug Inc. 3-[methyl or dimethyl)amino]-6-(pyridinyl)pyridazines and their cardiotonic use
US4503056A (en) * 1982-03-02 1985-03-05 Abbott Laboratories 1-(Pyridazinyl)pyrazoline derivatives
DE3825867A1 (de) * 1988-03-04 1989-09-14 Bayer Ag Heterocyclisch substituierte sulfonylaminoazole und ihre verwendung als herbizide
US5536701A (en) * 1994-10-11 1996-07-16 Monsanto Company 3-pyrazolyloxypyridazines, herbicidal compositions and uses thereof
EP1565150A1 (de) * 2002-11-20 2005-08-24 L'oreal Verwendung eines pyrazolcarboxamidderivates zur stimulation von keratinischem faserwachstum und/oder zur verhinderung von dessen verlust
FR2847160A1 (fr) * 2002-11-20 2004-05-21 Oreal Composition capillaire contenant un compose pyrasol-carboxamide, son utilisation pour stimuler la pousse des cheveux et/ou freiner leur chute
RU2442775C2 (ru) * 2005-07-04 2012-02-20 Хай Пойнт Фармасьютикалс, ЛЛС Антагонисты гистаминовых н3-рецепторов
CN103110635A (zh) 2005-07-04 2013-05-22 海波因特制药有限责任公司 组胺h3受体拮抗剂
EP2038256A1 (de) * 2006-05-23 2009-03-25 TransTech Pharma, Inc 6-(4-cyclopropylpiperazin-1-yl)-2'-methyl-[3,4']-bipyridin und seine verwendung als arzneimittel
EA016026B1 (ru) * 2006-05-29 2012-01-30 ХАЙ ПОЙНТ ФАРМАСЬЮТИКАЛЗ, ЭлЭлСи 3-(1,3-бензодиоксол-5-ил)-6-(4-циклопропилпиперазин-1-ил)пиридазин, его соли и сольваты и его применение в качестве антагониста н3 рецептора гистамина
EP2014656A3 (de) * 2007-06-11 2011-08-24 High Point Pharmaceuticals, LLC Neue heterocyclische H3-Antagonisten
AR081331A1 (es) 2010-04-23 2012-08-08 Cytokinetics Inc Amino- pirimidinas composiciones de las mismas y metodos para el uso de los mismos
EP2560488B1 (de) 2010-04-23 2015-10-28 Cytokinetics, Inc. Bestimmte aminopyrimidine und aminotriazine, zusammensetzungen daraus und verfahren zu ihrer verwendung
AR081626A1 (es) * 2010-04-23 2012-10-10 Cytokinetics Inc Compuestos amino-piridazinicos, composiciones farmaceuticas que los contienen y uso de los mismos para tratar trastornos musculares cardiacos y esqueleticos

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1595920B2 (de) * 1964-11-04 1978-08-10 Merck Patent Gmbh, 6100 Darmstadt 4-(co-Piperazinoalkyl)-pyrazole, ihre Salze und Verfahren zu ihrer Herstellung
JPS5831347B2 (ja) * 1975-09-05 1983-07-05 中外製薬株式会社 ピラゾリルピリダジンユウドウタイノ セイホウ

Also Published As

Publication number Publication date
FR2394542B1 (de) 1980-12-05
IT7824490A0 (it) 1978-06-13
CA1095912A (en) 1981-02-17
CS204029B2 (en) 1981-03-31
BE867967A (fr) 1978-12-11
NO149210C (no) 1984-03-07
AT357548B (de) 1980-07-10
DD140043A5 (de) 1980-02-06
IL54816A0 (en) 1978-07-31
BG28709A3 (en) 1980-06-16
US4251658A (en) 1981-02-17
SE7806576L (sv) 1978-12-14
NO149210B (no) 1983-11-28
PL111252B1 (en) 1980-08-30
CH638202A5 (de) 1983-09-15
SU797577A3 (ru) 1981-01-15
FI64156C (fi) 1983-10-10
YU140078A (en) 1983-01-21
HU175471B (hu) 1980-08-28
PL207570A1 (pl) 1979-05-21
FR2394542A1 (fr) 1979-01-12
AU521394B2 (en) 1982-04-01
NL7806380A (nl) 1978-12-15
FI781856A (fi) 1978-12-14
SU860703A1 (ru) 1981-08-30
DK263078A (da) 1978-12-14
FI64156B (fi) 1983-06-30
DE2825906A1 (de) 1979-01-18
NO782043L (no) 1978-12-14
ES470750A1 (es) 1979-01-16
JPS5416487A (en) 1979-02-07
GB1603958A (en) 1981-12-02
JPS569506B2 (de) 1981-03-02
IT1098216B (it) 1985-09-07
SE437517B (sv) 1985-03-04
AU3683678A (en) 1979-12-06
IL54816A (en) 1981-09-13

Similar Documents

Publication Publication Date Title
ATA414478A (de) Verfahren zur herstellung neuer 3-(pyrazol-1- yl)-pyridazin-derivate und der physiologisch vertraeglichen saeureadditions-salze dieser verbindungen
NO802498L (no) Fremgangsmaate for fremstilling av clavulansyresalter
DD137355A5 (de) Verfahren zur herstellung von phthalazin-derivaten
DK151009C (da) Analogifremgangsmaade til fremstilling af benzhydrylsulfinylforbindelser og fysiologisk acceptable syreadditionssalte deraf
SE429961B (sv) Forfarande for framstellning av mjolksyra
DD132869A5 (de) Verfahren zur herstellung neuer aminothiazolylazetamido-derivate
PT68044A (de) Verfahren zur herstellung neuer derivate des alkylendiami
DD134088A5 (de) Verfahren zur herstellung von neuen pyrrolidinderivaten
ATA292078A (de) Verfahren zur herstellung von neuen 9-amino- desoxyclavulansaeurederivaten
DD137438A5 (de) Verfahren zur herstellung von n'-phenyl-n-methylharnstoffderivaten
DD135283A5 (de) Verfahren zur herstellung von neuen aminoalkoxyphenyl-derivaten
AT359076B (de) Verfahren zur herstellung neuer 3-pyrazol-1-yl- pyridazin-derivate und der physiologisch ver- traeglichen saeureadditionssalze dieser ver- bindungen
AT359075B (de) Verfahren zur herstellung neuer pyridazinyl- -hydrazone und der physiologisch vertraeglichen saeureadditions-salze dieser verbindungen
PT65687A (de) Verfahren zu der herstellung und der verwendung des benzimidoylthionothiol-phosphorsaeureester als insektizide und akarizide
AT353286B (de) Verfahren zur herstellung von neuen 9- -hydroxyaethoxymethylguaninderivaten
RO81506A (ro) Procedeu pentru prepararea derivatilor acizilor 1,3,4-tiadiazol-2-carboxilici
PT72140A (de) Verfahren zur herstellung neuer derivate des 2-amino-aethanols
RO78158A (ro) Procedeu pentru prepararea acidului (2,2-dimetil-1,2-dihidrochinolin-4-il)-metilsulfonic
ATA802679A (de) Verfahren zur herstellung neuer pyridaziny -hydrazon-derivate und der physiologischen vertraeglichen saeureadditions-salze dieser verbindungen
DD134522A5 (de) Verfahren zur herstellung von 1,2,4-triazin-5-on-derivaten
LU79271A1 (de) Verfahren zur herstellung von neuen derivaten des 9-fluorprednisolons
ATA483678A (de) Verfahren zur herstellung des neuen 3-(4-brom- phenyl)-3-(3-pyridyl)-3-hydroxyprop-1-en und dessen saeureadditionssalzen
DD134868A5 (de) Verfahren zur herstellung neuer 1-phenyl-2-amino-1,3-propandiol-n-alkyl-derivate
ATA834378A (de) Verfahren zur herstellung von 2,6-pyridincarbon- saeure
SE442748B (sv) Forfarande for framstellning av etrar av klavulansyra

Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee