AR228851A1 - Procedimiento para preparar 9-hidroxi-9-aminoalquilflourenos y sus sales - Google Patents

Procedimiento para preparar 9-hidroxi-9-aminoalquilflourenos y sus sales

Info

Publication number
AR228851A1
AR228851A1 AR280279A AR28027980A AR228851A1 AR 228851 A1 AR228851 A1 AR 228851A1 AR 280279 A AR280279 A AR 280279A AR 28027980 A AR28027980 A AR 28027980A AR 228851 A1 AR228851 A1 AR 228851A1
Authority
AR
Argentina
Prior art keywords
alkylflourenes
hydroxy
salts
amino
preparing
Prior art date
Application number
AR280279A
Other languages
English (en)
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of AR228851A1 publication Critical patent/AR228851A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00Materials specially adapted for outerwear
    • A41D31/04Materials specially adapted for outerwear characterised by special function or use
    • A41D31/10Impermeable to liquids, e.g. waterproof; Liquid-repellent
    • A41D31/102Waterproof and breathable
    • AHUMAN NECESSITIES
    • A41WEARING APPAREL
    • A41DOUTERWEAR; PROTECTIVE GARMENTS; ACCESSORIES
    • A41D31/00Materials specially adapted for outerwear
    • A41D31/04Materials specially adapted for outerwear characterised by special function or use
    • A41D31/18Elastic
    • A41D31/185Elastic using layered materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/04Ortho- or ortho- and peri-condensed systems containing three rings
    • C07C2603/06Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
    • C07C2603/10Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
    • C07C2603/12Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
    • C07C2603/18Fluorenes; Hydrogenated fluorenes

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Textile Engineering (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AR280279A 1979-03-12 1980-03-12 Procedimiento para preparar 9-hidroxi-9-aminoalquilflourenos y sus sales AR228851A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US1953379A 1979-03-12 1979-03-12

Publications (1)

Publication Number Publication Date
AR228851A1 true AR228851A1 (es) 1983-04-29

Family

ID=21793707

Family Applications (6)

Application Number Title Priority Date Filing Date
AR280279A AR228851A1 (es) 1979-03-12 1980-03-12 Procedimiento para preparar 9-hidroxi-9-aminoalquilflourenos y sus sales
AR285806A AR228059A1 (es) 1979-03-12 1981-06-22 Un procedimiento para preparar 9-carboxamida-9-aminoalquil fluorenos y sus sales
AR285805A AR227318A1 (es) 1979-03-12 1981-06-22 Un procedimiento para preparar 9-ciano-9-aminoalquil-fluorenos v sus sales
AR285807A AR230983A1 (es) 1979-03-12 1981-06-22 Un procedimiento para preparar 9-carbamoil-9-aminoi-alquil fluorenos y sus sales
AR285808A AR229402A1 (es) 1979-03-12 1981-06-22 9-aminoalquilfluorenos utiles como intermediarios para preparar farmacos antiarritmicos,desprovistos de aplicaciones terapeuticas y sus sales
AR285804A AR225526A1 (es) 1979-03-12 1981-06-22 Un procedimiento para preparar 9-hidroxi-o-aminoalquilfluorenos y sus sales

Family Applications After (5)

Application Number Title Priority Date Filing Date
AR285806A AR228059A1 (es) 1979-03-12 1981-06-22 Un procedimiento para preparar 9-carboxamida-9-aminoalquil fluorenos y sus sales
AR285805A AR227318A1 (es) 1979-03-12 1981-06-22 Un procedimiento para preparar 9-ciano-9-aminoalquil-fluorenos v sus sales
AR285807A AR230983A1 (es) 1979-03-12 1981-06-22 Un procedimiento para preparar 9-carbamoil-9-aminoi-alquil fluorenos y sus sales
AR285808A AR229402A1 (es) 1979-03-12 1981-06-22 9-aminoalquilfluorenos utiles como intermediarios para preparar farmacos antiarritmicos,desprovistos de aplicaciones terapeuticas y sus sales
AR285804A AR225526A1 (es) 1979-03-12 1981-06-22 Un procedimiento para preparar 9-hidroxi-o-aminoalquilfluorenos y sus sales

Country Status (40)

Country Link
US (1) US4277495A (es)
EP (1) EP0018076B1 (es)
JP (1) JPS55124743A (es)
KR (2) KR840000279B1 (es)
AR (6) AR228851A1 (es)
AT (4) AT370407B (es)
AU (1) AU527992B2 (es)
BE (1) BE882166A (es)
CA (1) CA1136624A (es)
CH (1) CH643234A5 (es)
CS (4) CS214698B2 (es)
CY (1) CY1345A (es)
DD (1) DD149511A5 (es)
DE (1) DE3064872D1 (es)
DK (1) DK158658C (es)
EG (1) EG14592A (es)
ES (5) ES489470A0 (es)
FI (3) FI67211C (es)
FR (2) FR2460287A1 (es)
GB (1) GB2046257B (es)
GR (1) GR68035B (es)
GT (1) GT198062477A (es)
HK (1) HK101086A (es)
HU (1) HU179837B (es)
IE (1) IE49553B1 (es)
IL (1) IL59558A (es)
IT (1) IT1140772B (es)
LU (1) LU82236A1 (es)
MA (1) MA18763A1 (es)
MY (1) MY8700080A (es)
NZ (1) NZ193078A (es)
OA (1) OA06486A (es)
PH (1) PH15594A (es)
PL (1) PL122643B1 (es)
PT (1) PT70927A (es)
RO (2) RO79822A (es)
SG (1) SG72286G (es)
SU (2) SU1022656A3 (es)
YU (1) YU65680A (es)
ZA (1) ZA801422B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4212337A (en) * 1978-03-31 1980-07-15 Union Carbide Corporation Closure fastening device
US4452745A (en) * 1981-02-06 1984-06-05 Eli Lilly And Company 9-Aminoalkylfluorenes
US4484352A (en) * 1983-02-07 1984-11-20 Katzin Lawrence F Reclosable plastic bag
US4552982A (en) * 1983-08-01 1985-11-12 Eli Lilly And Company Synthesis of 9-carbamoyl-9-(3-aminopropyl)fluorenes
US4508735A (en) * 1983-09-21 1985-04-02 Eli Lilly And Company Anti-arrhythmic N-alkanoylaminoalkyl fluorenes
FI844067L (fi) * 1983-10-19 1985-04-20 Lilly Co Eli Foerfarande foer framstaellning av 9-karbamoylfluorenderivat.
US4585894A (en) * 1983-10-19 1986-04-29 Eli Lilly And Company Process for producing 9-carbamoyl fluorene derivatives
US4486592A (en) * 1983-10-19 1984-12-04 Eli Lilly And Company 9-Carbamoylfluorene derivatives
DE3444837A1 (de) * 1984-12-08 1986-06-12 Basf Ag, 6700 Ludwigshafen 10,11-dihydro-5h-dibenzo(a,d)cycloheptadien- derivate, ihre herstellung und verwendung
GB9304189D0 (en) * 1993-03-02 1993-04-21 Sturmey Archer Ltd Epicyclic change speed gear hubs
US5739135A (en) * 1993-09-03 1998-04-14 Bristol-Myers Squibb Company Inhibitors of microsomal triglyceride transfer protein and method
US5631203A (en) * 1995-05-04 1997-05-20 Phillips Petroleum Company Metallocene compounds and preparation thereof containing terminal alkynes
ATE264833T1 (de) * 1996-01-16 2004-05-15 Bristol Myers Squibb Co Konformationseingeschränkte aromatische inhibitoren des microsomalen triglyceridtransferproteins und verfahren
US5760246A (en) 1996-12-17 1998-06-02 Biller; Scott A. Conformationally restricted aromatic inhibitors of microsomal triglyceride transfer protein and method

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB736372A (en) * 1953-05-06 1955-09-07 Miles Lab Fluorene derivatives
FR1345419A (fr) * 1962-12-21 1963-12-06 Boehringer & Soehne Gmbh Procédé pour la préparation de dérivés basiques du fluorène et des sels de ces dérivés
NL287095A (es) 1962-12-21 1965-02-25
DE1203253B (de) * 1963-02-09 1965-10-21 Boehringer & Soehne Gmbh Verfahren zur Herstellung basischer Fluorenderivate und ihrer Salze
FR1482727A (fr) * 1965-06-10 1967-05-26 Upjohn Co 9-(2-amino-1-méthyléthyl) fluoren-9-ols et leur procédé de fabrication
GB1211459A (en) * 1967-05-10 1970-11-04 Abbott Lab Hydroxy amines
US3660485A (en) * 1970-10-05 1972-05-02 Searle & Co Fluorene-9-carboxylic acid hydrazides
US3843657A (en) * 1972-12-08 1974-10-22 Searle & Co 9-dialkylamin oalkyl-n-substituted fluorene-9-carboxamides

Also Published As

Publication number Publication date
CS214699B2 (en) 1982-05-28
AU527992B2 (en) 1983-03-31
AR230983A1 (es) 1984-08-31
FR2457278A1 (fr) 1980-12-19
KR840001836B1 (ko) 1984-10-22
AR228059A1 (es) 1983-01-14
ES8104186A1 (es) 1981-04-16
PL122643B1 (en) 1982-08-31
JPS55124743A (en) 1980-09-26
FI69299C (fi) 1986-01-10
AU5630180A (en) 1980-09-18
IE800494L (en) 1980-09-12
SU1015820A3 (ru) 1983-04-30
AT368130B (de) 1982-09-10
FI840921A0 (fi) 1984-03-07
ATA114081A (de) 1982-01-15
CH643234A5 (fr) 1984-05-30
ES497303A0 (es) 1982-01-01
AT368125B (de) 1982-09-10
DE3064872D1 (en) 1983-10-27
EP0018076B1 (en) 1983-09-21
DK103380A (da) 1980-09-13
OA06486A (fr) 1981-07-31
FI67211B (fi) 1984-10-31
GR68035B (es) 1981-10-27
IT1140772B (it) 1986-10-10
GT198062477A (es) 1981-09-02
ES8201947A1 (es) 1982-01-01
CS214698B2 (en) 1982-05-28
FI840920A0 (fi) 1984-03-07
ATA113981A (de) 1982-01-15
CA1136624A (en) 1982-11-30
AT370407B (de) 1983-03-25
SG72286G (en) 1987-03-27
EG14592A (en) 1985-03-31
ES8201946A1 (es) 1982-01-01
SU1022656A3 (ru) 1983-06-07
HK101086A (en) 1987-01-02
ES8201945A1 (es) 1982-01-01
DK158658C (da) 1990-12-31
FR2460287B1 (es) 1983-03-11
BE882166A (fr) 1980-09-11
GB2046257B (en) 1983-10-19
GB2046257A (en) 1980-11-12
FI840920A (fi) 1984-03-07
JPS6314702B2 (es) 1988-04-01
IL59558A (en) 1984-05-31
CY1345A (en) 1987-01-16
NZ193078A (en) 1981-11-19
CS214700B2 (en) 1982-05-28
IE49553B1 (en) 1985-10-30
ES8201943A1 (es) 1982-01-01
HU179837B (en) 1982-12-28
FI800735A (fi) 1980-09-13
AR227318A1 (es) 1982-10-15
EP0018076A1 (en) 1980-10-29
MY8700080A (en) 1987-12-31
FI67211C (fi) 1985-02-11
DD149511A5 (de) 1981-07-15
KR830001860A (ko) 1983-05-19
ES497301A0 (es) 1982-01-01
RO79822A (ro) 1983-02-01
FI840921A (fi) 1984-03-07
ATA114181A (de) 1982-01-15
AR225526A1 (es) 1982-03-31
MA18763A1 (fr) 1980-10-01
DK158658B (da) 1990-07-02
ES489470A0 (es) 1981-04-16
ATA134480A (de) 1982-08-15
PH15594A (en) 1983-02-28
IL59558A0 (en) 1980-06-30
FI70006B (fi) 1986-01-31
FI69299B (fi) 1985-09-30
US4277495A (en) 1981-07-07
CS214696B2 (en) 1982-05-28
LU82236A1 (fr) 1980-06-06
PL222600A1 (es) 1980-12-15
PT70927A (en) 1980-04-01
IT8020502A0 (it) 1980-03-11
FR2457278B1 (es) 1984-06-29
ES497300A0 (es) 1982-01-01
FR2460287A1 (fr) 1981-01-23
RO85074A (ro) 1984-08-17
KR840000279B1 (ko) 1984-03-13
AR229402A1 (es) 1983-08-15
FI70006C (fi) 1986-09-12
ES497302A0 (es) 1982-01-01
YU65680A (en) 1983-02-28
ZA801422B (en) 1981-10-28
AT368131B (de) 1982-09-10

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