AR086281A1 - Composiciones y metodos que comprenden variantes de serina proteasas - Google Patents

Composiciones y metodos que comprenden variantes de serina proteasas

Info

Publication number
AR086281A1
AR086281A1 ARP120101585A ARP120101585A AR086281A1 AR 086281 A1 AR086281 A1 AR 086281A1 AR P120101585 A ARP120101585 A AR P120101585A AR P120101585 A ARP120101585 A AR P120101585A AR 086281 A1 AR086281 A1 AR 086281A1
Authority
AR
Argentina
Prior art keywords
variants
subtilisin
amino acid
specifically
serine protease
Prior art date
Application number
ARP120101585A
Other languages
English (en)
Original Assignee
Danisco Us Inc
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Us Inc, Procter & Gamble filed Critical Danisco Us Inc
Publication of AR086281A1 publication Critical patent/AR086281A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Cleaning By Liquid Or Steam (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La presente solicitud proporciona variantes de serina proteasa, más específicamente a las variantes de subtilisina producidas a partir de ella. En forma específica, la presente solicitud proporciona variantes de serina proteasa, más específicamente variantes de subtilisinas que tienen una o más sustituciones en comparación con una serina proteasa de referencia. Además, la presente proporciona composiciones que comprenden estas variantes de serina proteasa, más específicamente variantes de subtilisina. En algunas formas de realización, la presente proporciona composiciones de limpieza que comprenden al menos una de estas variantes de serina proteasa, más específicamente variantes de subtilisina.Reivindicación 1: Una variante de subtilisina aislada, donde dicha variante de subtilisina es una forma madura que tiene actividad proteolítica y comprende una secuencia de aminoácidos que comprende una combinación de sustituciones de aminoácidos en posiciones seleccionadas de T022R + V104I + Q245R, G020R + S024R + S101A, T022R + S103A + V104I, T022R + V104I + A232V, T022R + S103A + Q245R, T022R + A232V + Q245R, T022R + S103A + A232V, T022R + S103A + V104I + A232V, T022R + V104I + A232V + Q245R, T022R + S103A + V104l + Q245R, T022R + S103A + A232V + Q245R, T022R + S103A + V104I + A232V + Q245R, T022A + N076D + S103A + V104I + A232V + Q245R, T022A + N076D + S103A + V104I + A232V, T022A + N076D + V104l + A232V + Q245R, T022A + N076D + S103A + A232V + Q245R, T022A + N076D + S103A + V104I + Q245R, T022A + N076D + V104I + Q245R, T022A + N076D + A232V + Q245R, T022A + N076D + V104I + A232V, T022A + N076D + S103A + Q245R, T022A + N076D + S103A + A232V, T022A + N076D + S103A + V104I, T022A + N076D + S103A, T022A + N076D + V104I, T022A + N076D + A232V, T022A + N076D + Q245R, G020R + S101A + T213A, G020R + R045T + S101A, G020R + S101A + G211Q, S024R + S101A + T213A, G020R + T022W + S101A, S024R + S101A + G211Q, N043R + S101A + T213A, N043R + R045T + S101A, S024R + N043R + S101A, S024R + R045T + S101A, S101A + G211Q + T213A, G020R + N043R + S101A, R045T + S101A + T213A, T022W + S024R + S101A, T022R + S101G + V104I, T022W + S101A + T213A, T022R + S101G + Q245R, T022W + S101A + G211Q, G020R + S024R + Q245R, T022R + S101G + V104l + Q245R, T022R + S101G + A232V, T022R + S101G + S103A, T022R + S101G + S103A + V104I, T022R + S101G + S103A + Q245R, T022R + S101G + A232V + Q245R, T022R + S101G + V104I + A232V, G020R + S024R + S101A + T213A, G020R + S024R + T213A + S101N + V104I + A232V, S101N + S103A + V104I, S101N + S103A + A232V, S101N + S103A + V104l + A232V, G020R + S103A + A232V, G020R + V104I + A232V, G020R + S103A + V104I + A232V, G020R + S103A + V104I, N018R + N076D + N116A, N018R + N076D + T213A, N018R + N076D + S101A, N018R + N076D + A215F, ó N018R + N076D + G211Q, y donde las posiciones de aminoácidos de la variante de subtilisina se numeran de acuerdo con la numeración de las correspondientes posiciones de aminoácidos en la secuencia de aminoácidos de la subtilisina BPN’ de BaciIIus amiloliquefaciens mostradas en la SEQ ID Nº 1.
ARP120101585A 2011-05-05 2012-05-04 Composiciones y metodos que comprenden variantes de serina proteasas AR086281A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161482938P 2011-05-05 2011-05-05

Publications (1)

Publication Number Publication Date
AR086281A1 true AR086281A1 (es) 2013-12-04

Family

ID=46147719

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP120101585A AR086281A1 (es) 2011-05-05 2012-05-04 Composiciones y metodos que comprenden variantes de serina proteasas

Country Status (13)

Country Link
US (1) US9856466B2 (es)
EP (3) EP3486319B1 (es)
JP (2) JP6105560B2 (es)
CN (1) CN103764823B (es)
AR (1) AR086281A1 (es)
BR (1) BR112013027963A2 (es)
CA (3) CA2834865C (es)
DK (1) DK2705146T3 (es)
ES (1) ES2707869T3 (es)
MX (1) MX338925B (es)
RU (1) RU2718648C2 (es)
TR (1) TR201901382T4 (es)
WO (1) WO2012151534A1 (es)

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