YU46758B - Genomna modifikacija kvasca roda pichia koja je selektivna po lokaciji - Google Patents

Genomna modifikacija kvasca roda pichia koja je selektivna po lokaciji

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Publication number
YU46758B
YU46758B YU180386A YU180386A YU46758B YU 46758 B YU46758 B YU 46758B YU 180386 A YU180386 A YU 180386A YU 180386 A YU180386 A YU 180386A YU 46758 B YU46758 B YU 46758B
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YU
Yugoslavia
Prior art keywords
pichia
gene
alcohol oxidase
dna sequences
disrupted
Prior art date
Application number
YU180386A
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English (en)
Other versions
YU180386A (sh
Inventor
J.M. Cregg
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Phillips Petroleum Company
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Filing date
Publication date
Application filed by Phillips Petroleum Company filed Critical Phillips Petroleum Company
Publication of YU180386A publication Critical patent/YU180386A/sh
Publication of YU46758B publication Critical patent/YU46758B/sh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/90—Stable introduction of foreign DNA into chromosome
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

Abstract

GENOMNA MODIFIKACIJA KVASCA RODA PICHIA KOJA JE SELEKTIVNA PO LOKACIJI, naznačen time, što obuhvata transformisanje soja domaćih roda Pichia sa serijski postavljenim linearnim DNA fragmentom koji obuhvata prvi umetajući DNA fragment, selektirajući markerski gen i drugi umetajući DNA fragment; pri čemu su pomenuti prvi i drugi umetajući DNA fragmenti svaki dužine najmanje oko 200 nukleotida i imaju nukleotifne sekvence koje su homologe sa posebnim delovima nativnog Pichia genomsnog mesta na kojem treba da se javi genomna modifikacija; i pri čemu su pomenuti prvi i drugi umetajući DNA fragmenti orijentisani jedan u odnosu na drugi u pomenutom linearnom fragmentu kao što su orijentisani u genomu Pichia; i pri čemu je pomenuti markerski gen postavljen izmedju prvog umetajućeg DNA fragmenta i drugog umetajućeg DNA fragmenta. Prijava sadrži još 3 nezavisna i 25 zavisnih zahteva.
YU180386A 1985-10-25 1986-10-23 Genomna modifikacija kvasca roda pichia koja je selektivna po lokaciji YU46758B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/791,013 US4882279A (en) 1985-10-25 1985-10-25 Site selective genomic modification of yeast of the genus pichia

Publications (2)

Publication Number Publication Date
YU180386A YU180386A (sh) 1992-12-21
YU46758B true YU46758B (sh) 1994-05-10

Family

ID=25152397

Family Applications (1)

Application Number Title Priority Date Filing Date
YU180386A YU46758B (sh) 1985-10-25 1986-10-23 Genomna modifikacija kvasca roda pichia koja je selektivna po lokaciji

Country Status (26)

Country Link
US (1) US4882279A (sh)
EP (2) EP0226752B1 (sh)
JP (1) JP2614215B2 (sh)
KR (1) KR930002738B1 (sh)
CN (1) CN86107108A (sh)
AT (2) ATE197962T1 (sh)
AU (2) AU581107B2 (sh)
CA (1) CA1339209C (sh)
DD (1) DD255544A5 (sh)
DE (2) DE3689411T2 (sh)
DK (1) DK510786A (sh)
EG (1) EG17985A (sh)
ES (2) ES2061433T3 (sh)
FI (1) FI98931C (sh)
HU (1) HU208552B (sh)
IE (1) IE68454B1 (sh)
IL (1) IL80286A (sh)
IN (1) IN166443B (sh)
MX (1) MX168390B (sh)
NO (1) NO176923C (sh)
NZ (1) NZ217809A (sh)
PH (1) PH25990A (sh)
PL (1) PL154843B1 (sh)
PT (1) PT83618B (sh)
YU (1) YU46758B (sh)
ZA (1) ZA867650B (sh)

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