UY30220A1 - Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo - Google Patents

Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo

Info

Publication number
UY30220A1
UY30220A1 UY30220A UY30220A UY30220A1 UY 30220 A1 UY30220 A1 UY 30220A1 UY 30220 A UY30220 A UY 30220A UY 30220 A UY30220 A UY 30220A UY 30220 A1 UY30220 A1 UY 30220A1
Authority
UY
Uruguay
Prior art keywords
compounds
methods
tetrahydropiridotienopirimidina
pharmaceutical compositions
disorders
Prior art date
Application number
UY30220A
Other languages
English (en)
Inventor
Chetan Darne
Kristin Allegue
Kanwar Sidhu
Zheng Liu
Jason Newcom
Dr Mario Lobell
Qian Zhao
Gaetan H Ladouceur
Chengzhi Zhang
Original Assignee
Bayer Pharmaceuticals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Pharmaceuticals Corp filed Critical Bayer Pharmaceuticals Corp
Publication of UY30220A1 publication Critical patent/UY30220A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

La presente invencion se relaciona con compuestos de la formula (I) en la cual las variables son las descriptas en la memoria descriptiva, con composiciones farmacéuticas que los contienen, con métodos para la preparacion de los compuestos y composiciones farmacéuticas para el tratamiento o prevencion de trastornos, en particular el cáncer.
UY30220A 2006-03-20 2007-03-19 Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo UY30220A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78414606P 2006-03-20 2006-03-20

Publications (1)

Publication Number Publication Date
UY30220A1 true UY30220A1 (es) 2007-10-31

Family

ID=38523058

Family Applications (1)

Application Number Title Priority Date Filing Date
UY30220A UY30220A1 (es) 2006-03-20 2007-03-19 Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo

Country Status (29)

Country Link
US (1) US8501755B2 (es)
EP (1) EP2001890B1 (es)
JP (1) JP5282026B2 (es)
KR (1) KR20080110834A (es)
CN (1) CN101448840B (es)
AR (1) AR059901A1 (es)
AT (1) ATE495179T1 (es)
AU (1) AU2007227317A1 (es)
BR (1) BRPI0711045A2 (es)
CA (1) CA2647036C (es)
CR (1) CR10304A (es)
DE (1) DE602007011906D1 (es)
DO (1) DOP2007000053A (es)
EC (1) ECSP088749A (es)
ES (1) ES2357654T3 (es)
GT (1) GT200800187A (es)
IL (1) IL194028A0 (es)
MA (1) MA30351B1 (es)
MX (1) MX2008012006A (es)
NZ (1) NZ571326A (es)
PA (1) PA8719401A1 (es)
PE (1) PE20080144A1 (es)
RU (1) RU2008141239A (es)
SV (1) SV2008003032A (es)
TN (1) TNSN08370A1 (es)
TW (1) TW200804397A (es)
UY (1) UY30220A1 (es)
WO (1) WO2007109279A2 (es)
ZA (1) ZA200808017B (es)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8399666B2 (en) 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
GB2431927B (en) 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
JP5461402B2 (ja) * 2007-09-14 2014-04-02 バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング 置換三環式化合物およびその使用方法
MX2010012814A (es) 2008-05-23 2010-12-20 Amira Pharmaceuticals Inc Inhibidor de proteina activadora de 5-lipoxigenasa.
WO2010054285A2 (en) * 2008-11-10 2010-05-14 National Health Research Institutes Fused bicyclic and tricyclic pyrimidine compounds as tyrosine kinase inhibitors
WO2013112699A2 (en) * 2012-01-25 2013-08-01 Proteostasis Therapeutics, Inc. Proteasome activity enhancing compounds
US20170107229A1 (en) * 2014-05-26 2017-04-20 Bayer Pharma Aktiengesellschaft Substituted tetrahydropyridothienopyrimidines
US10561749B2 (en) 2015-07-03 2020-02-18 Kyoto University Nuclear medicine diagnostic imaging agent
KR102474326B1 (ko) 2016-06-22 2022-12-05 반더빌트유니버시티 무스카린성 아세틸콜린 수용체 m4의 양성 알로스테릭 조절제
US11008335B2 (en) 2016-11-07 2021-05-18 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor M4
EP3558309B1 (en) 2016-11-07 2023-07-26 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor m4
WO2018085813A1 (en) 2016-11-07 2018-05-11 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor m4
TW201930311A (zh) 2017-12-05 2019-08-01 泛德比爾特大學 蕈毒鹼型乙醯膽鹼受體m4之正向別構調節劑
WO2019113174A1 (en) 2017-12-05 2019-06-13 Vanderbilt University Positive allosteric modulators of the muscarinic acetylcholine receptor m4
WO2020191151A1 (en) * 2019-03-19 2020-09-24 Oncovalent Therapeutics Inc. Sumo inhibitor compounds and uses thereof
WO2023015240A1 (en) * 2021-08-05 2023-02-09 Bristol-Myers Squibb Company Tricyclic fused pyrimidine compounds for use as her2 inhibitors
CN114736154B (zh) * 2022-03-15 2023-07-21 安庆朗坤药业有限公司 N-（3-氯-4-（2-吡啶甲氧基）苯基）-2-氰基乙酰胺的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3453900A (en) * 1999-03-30 2000-10-23 Nippon Soda Co., Ltd. Thienopyrimidine compounds and salts thereof and process for the preparation of the same
DE19944604A1 (de) * 1999-09-17 2001-03-22 Merck Patent Gmbh Aminderivate
US6608053B2 (en) 2000-04-27 2003-08-19 Yamanouchi Pharmaceutical Co., Ltd. Fused heteroaryl derivatives
WO2003035653A1 (fr) * 2001-10-26 2003-05-01 Nippon Soda Co.,Ltd. Compose pyridothienopyrimidine et son sel
CA2530281C (en) 2003-07-24 2013-02-12 Bayer Pharmaceuticals Corporation Substituted tetrahydrobenzothienopyrimidinamine compounds useful for treating hyper-proliferative disorders

Also Published As

Publication number Publication date
AR059901A1 (es) 2008-05-07
ZA200808017B (en) 2009-11-25
CA2647036C (en) 2015-06-23
MX2008012006A (es) 2008-10-03
NZ571326A (en) 2011-07-29
CN101448840A (zh) 2009-06-03
WO2007109279A3 (en) 2007-12-21
ATE495179T1 (de) 2011-01-15
JP5282026B2 (ja) 2013-09-04
TW200804397A (en) 2008-01-16
PA8719401A1 (es) 2009-02-09
US8501755B2 (en) 2013-08-06
CA2647036A1 (en) 2007-09-27
CR10304A (es) 2009-01-27
AU2007227317A1 (en) 2007-09-27
EP2001890B1 (en) 2011-01-12
ES2357654T3 (es) 2011-04-28
MA30351B1 (fr) 2009-04-01
CN101448840B (zh) 2011-12-14
US20100298297A1 (en) 2010-11-25
SV2008003032A (es) 2009-11-26
RU2008141239A (ru) 2010-04-27
JP2009530387A (ja) 2009-08-27
TNSN08370A1 (en) 2009-12-29
WO2007109279A2 (en) 2007-09-27
DOP2007000053A (es) 2007-09-30
ECSP088749A (es) 2008-10-31
EP2001890A2 (en) 2008-12-17
IL194028A0 (en) 2009-09-22
DE602007011906D1 (de) 2011-02-24
BRPI0711045A2 (pt) 2012-06-26
PE20080144A1 (es) 2008-04-06
GT200800187A (es) 2009-04-07
KR20080110834A (ko) 2008-12-19

Similar Documents

Publication Publication Date Title
UY30220A1 (es) Compuestos de tetrahidropiridotienopirimidina y metodos para su empleo
GT200900027A (es) Compuestos organicos
DOP2006000061A (es) Derivados de pirimidina para el tratamiento de trastornos hiperproliferativos
GT200800184A (es) Aminotetrahidropiranos como inhibidores de dipeptidil peptidasa-iv para el tratamiento o prevencion de diabetes.
BR112014000792A2 (pt) compostos de piperidinila para uso como inibidores da tanquirase
UA107783C2 (en) Isoindoline compounds for use in treating cancer
EA200901032A1 (ru) Соединения и композиции в качестве модуляторов активности gpr119
EA200870415A1 (ru) Хиназолины для ингибирования pdk 1
ECSP099445A (es) Quinazolinas para la inhibición de pdk1
UY32359A (es) Compuestos de plasmalogenos, composiciones farmaceuticas que los contienen y metodos para tratar enfermedades del envejecimiento
PA8842101A1 (es) Heteroarilos sustituidos
EA200901166A1 (ru) Соединения и композиции в качестве модуляторов активности gpr 119
CL2011000691A1 (es) Compuestos derivados de nicotinamida sustituida; composicion farmaceutica que los comprende; uso para el tratamiento y/o prevencion de cancer, infecciones, enfermedades inflamatorias y autoinmunitarias.
ECSP11010798A (es) 1,2,5-oxadiazoles como inhibidores de indolamina 2,3-dioxigenasa
EA201300242A1 (ru) Фармацевтические композиции, содержащие замещенные ациланилиды
CL2008000789A1 (es) Compuestos derivados de adenina; composicion farmaceutica que comprende a dichos compuestos, utiles para tratar enfermedades alergicas, virales o cancer, entre otras.
ECSP099465A (es) Polimorfos de sal de succinato 2-[6-(3-amino-piperidin-1-ilo)-3-metil-2,4-dioxo-3,4-dihidro-2h-pirimidin-1-ilmetil]-4-fluoro-benzonitrilo y métodos
BRPI0818672A2 (pt) 2'-fluor-2'-desoxitetra-hidrouridinas como inibidores da citidina desaminase
NO20090596L (no) Antivirale fosfinatforbindelser
UY29079A1 (es) Acidos fenoxiacéticos sustituidos, composiciones que los contienen, procedimientos de preparación y aplicaciones
GT200600161A (es) Nuevas combinaciones terapeuticas para el tratamiento o la prevencion de los trastornos psicoticos
UY32937A (es) Compuestos y composiciones como moduladores de la actividad de gpr119
SV2010003650A (es) INHIBIDORES HETEROCICLICOS DE ESTEAROIL-CoA-DESATURASA
CR8636A (es) Compuestos utiles para el tratamiento de enfermedades
UY31322A1 (es) Amidas heterocíclicas y sus métodos de uso-975

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20170608